National Paralysis Resource Center

The overall purpose of the Older Adult Home Modification Program (OAHMP) is to assist experienced nonprofit organizations, state and local governments, and public housing authorities in undertaking comprehensive programs that make safety and functional home modification repairs and renovations to meet the needs of low-income seniors. The goal of the home modification program is to enable low-income elderly persons to remain in their homes through low-cost, low barrier, high impact home modifications to reduce older adults" risk of falling, improve general safety, increase accessibility, and to improve their functional abilities in their home. This will enable older adults to remain in their homes, that is, to "age in place," rather than move to nursing homes or other assisted care facilities.

In response to a longstanding congressional mandate (P.L. 98-619, Departments of Labor, Health and Human Services, and Education and Related Agencies Appropriation Act, 1985), NIMHD invites applications from eligible institutions to establish a national coordinating center (CC) for the Research Centers in Minority Institutions (RCMIs) initiative. The RCMI CC will coordinate activities across funded RCMI U54 Centers, prospectively evaluate the overall RCMI program, and serve as a national resource to help these centers achieve their primary goals. The RCMI CC will be responsive to requests generated by RCMI site key personnel, NIMHD, NIH, the scientific community, and the general public.

The overarching goal of this notice of funding opportunity (NOFO) and its companion opportunities is to establish the Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) Program to support development of innovative, reliable, cost-effective, and sustainable multimodal AI-based clinical decision support (CDS) tools. PRIMED-AI CDS tools are based on the integration of clinical imaging with other types of multimodal health data to enhance care for patients with a wide range of health conditions. The PRIMED-AI Program seeks to catalyze the adoption of AI-based CDS tools into clinical workflows to enable novel personalized medicine strategies that address significant health challenges. The purpose of this NOFO is to solicit applications for the creation of a Validation Center to serve as a dedicated hub for the comprehensive evaluation and characterization of AI-enabled, image-based, multimodal CDS tools developed by the PRIMED-AI Consortium, to ensure these tools are reliable, reproducible, and generalizable. The Validation Center will focus on verification, validation, interoperability, and uncertainty quantification to comprehensively characterize performance of the CDS tools developed by the program. The core functions of the Validation Center will involve the systematic validation of PRIMED-AI Consortium deliverables, including those emerging from award recipients under the Playbook, Data-to-Model Academic-Industrial Partnerships, and Model-to-Clinic NOFOs.

The Medical Student Education (MSE) Program provides support to public medical schools in the top quartile of states with a projected primary care provider shortage to expand or support education for medical students preparing to become physicians.

The purpose of this Notice of Funding Opportunity (NOFO) is to support the next 5-year award period of the Clinician-Scientist Transdisciplinary Aging Research Coordinating Center (Clin-STAR CC), whose mission is to serve as a national resource for clinician-investigators across specialties and disciplines who are focusing their careers on aging research. This NOFO intends to build upon NIA's substantial investments to foster the development of clinician-scientists across specialties and disciplines. The specific goals of this initiative are to convey scientific and research knowledge on aging research; foster networking and collaboration between clinician-scientist leaders in aging research and clinician-investigators across specialties and disciplines who wish to focus on aging research; provide mentoring and career development support for emerging clinician-scientists committed to pursuing aging research in their clinical specialty or discipline; and advance interdisciplinary research projects in aging. Ultimately, the Clin-STAR CC is intended to provide a multi-faceted national research platform leading to improved patient-centered care for older adults across specialties and disciplines.

The NIH Director"s Pioneer Award supports individual scientists of exceptional creativity who propose bold and highly innovative research projects with the potential to produce a major impact on broad, important areas relevant to the mission of NIH. To be considered pioneering, the proposed research must reflect substantially different scientific directions from those already being pursued in the investigator"s research program or elsewhere. Applications in all topics relevant to the broad mission of NIH are welcome. Research may involve basic, translational, or clinical research. The NIH Director"s Pioneer Award is a component of the High-Risk, High-Reward Research (HRHR) program of the NIH Common Fund.

Cooperative agreements under the Alzheimer"s Disease Programs Initiative (ADPI)- State Programs for Dementia-Specific Respite Notice of Funding Opportunity (NOFO) is to expand and strengthen additional supports for family caregivers by providing dementia-specific respite services delivered through the National Aging Services Network (State Units on Aging (SUA), Area Agencies on Aging (AAA), and aging network service providers). The program is designed to provide respite relief in support of unpaid family caregivers of people with a probable diagnosis of Alzheimer"s disease or related dementia (ADRD) who need access or additional access to respite care or related services. The primary goal is to reduce caregiver burden and delay institutionalization of people with a probable diagnosis of ADRD through the availability and delivery of dementia-specific respite services. Through this demonstration grant opportunity, states will partner with Area Agencies on Aging (AAA) to coordinate and provide respite services for caregivers with a focus on dementia-specific respite services comparable to existing services provided under the Older Americans Act (OAA). Grant funds will be awarded to SUAs, which will distribute the funds to AAAs to carry out program implementation.Dementia-specific respite services will be made available to eligible unpaid family caregivers of people with a probable diagnosis of ADRD, as well as those under age 60 with younger-onset dementia of any age who would otherwise meet eligibility requirements under OAA funded programs. Participating SUAs will establish and define the terms and conditions governing the implementation of their dementia-specific respite program. Successful applications will include an independent third-party evaluation to assess and document the program"s impact on participating, community-residing unpaid family caregivers and individuals living with dementia.

The purpose of this Notice of Funding Opportunity is to support one organization through a cooperative agreement to serve as the National Falls Prevention Resource Center. This center will act as a central connector to the aging network for the discretionary and formula funded Falls Prevention grants. It will offer individualized and tiered technical assistance, high-quality education, and a wide range of resources to increase the number of older adults and adults with disabilities who participate in evidence based Falls Prevention Programs. The Resource Center will help the network provide cost-effective services that align with the purposes of the Older Americans Act, Title III-D. They will promote the advancement of the Falls Prevention network through building partnerships, supporting data collection, reporting metrics, highlighting key achievements, and engaging stakeholders to encourage long-term sustainability of the programs.

This grant is funded under the Projects of National Significance (PNS) authorized by the Developmental Disabilities Assistance and Bill of Rights Act. Its purpose is to increase awareness, access, and use of ABLE (Achieving a Better Life Experience) accounts so that individuals with disabilities have the resources needed to better support their health and economic well-being and improve their economic security and mobility. Since 2015, the ABLE Act has authorized states and territories to establish tax-advantaged programs—ABLE accounts—that allow individuals with disabilities to save and invest money. These accounts may be used for qualified disability expenses, including education, food, housing, transportation, employment training, assistive technology, and health care. Beginning in January 2026, ABLE eligibility requirements were expanded to include individuals with an age of disability onset up to 46, increased from the previous limit of 26. As a result, an estimated 14 million people will be eligible for ABLE accounts, including approximately 1.2 million veterans. This expansion presents a significant opportunity to broaden outreach to individuals receiving Medicaid and Supplemental Security Income (SSI), as well as individuals with disabilities who are not enrolled in disability benefit programs, to help overcome barriers to achieving good health and meaningful employment. To advance these goals, the grant will support strategies such as coordinated marketing efforts at the national, state, and community levels; population-specific approaches implemented through partnerships with ACL grantees and community stakeholders; and a strengthened systems approach at the state level. ACL recognizes that ABLE-related supports can play a critical role in increasing economic security and mobility for individuals with disabilities.

The purpose of NIDILRR's Disability and Rehabilitation Research Project (DRRP) grants is to improve the effectiveness of services authorized under the Rehabilitation Act by generating knowledge or developing methods, procedures, and rehabilitation technologies that advance a wide range of independent living and employment outcomes for individuals with disabilities, especially those with the greatest support needs. Under this particular opportunity, a DRRP must conduct knowledge translation and related activities in collaboration with the Burn Model System, Spinal Cord Injury (SCI) Model System, and Traumatic Brain Injury (TBI) Model System grantees. Specifically, the MSKTC will be required to collaborate with the model system centers to produce and promote systematic reviews of existing research and information products for SCI, TBI, and Burn; identify and implement effective strategies for disseminating SCI, TBI, and Burn Model System programs" research findings; serve as the central resource for the Model System programs' knowledge and product dissemination; and provide training and technical assistance in knowledge translation for the Model System grantees. This grant will have a 60-month project period, with five 12-month budget periods.