Pilot Studies of Biological, Behavioral and Social Mechanisms Contributing to HIV Pathogenesis Within the Mission of NIDDK (R21 Clinical Trial Not Allowed)

AMS will award these funds competitively to at least one eligible organization that meets program requirements and whose expertise is consistent with the purpose of the grant program. The selected grant recipient(s) will provide management, oversight, consultation and expertise necessary to advance the purpose and activities of the program, primarily through a subaward program to support cold storage within the middle of the supply chain. These equipment investments will be made through subawards to food banks, faith-based organizations, and other public or private nonprofit organizations that provide nutrition assistance, such as prepared meals or food for use at home, to people with low-income or challenging financial circumstances.

The U.S. Department of Agriculture, Animal and Plant Health Inspection Service announce this funding opportunity to carry out the Plant Protection Act Section 7721 (PPA 7721) National Clean Plant Network (NCPN) program. APHIS will consider project proposals that clearly and directly support the strategic goals and objectives of the National Clean Plant Network as described in the NCPN Strategic Plan . The purpose of the NCPN program is to establish a network of Clean Plant Centers for diagnostic and pathogen elimination services to produce clean propagative plant material and to maintain blocks of pathogen-tested plant material in sites located throughout the United States. The NCPN provides propagative plant material free of targeted plant pathogens to protect the environment and ensure the global competitiveness of U.S. specialty crop producers. Program priorities align with the goals specified in the NCPN Strategic Plan and include: 1) Optimizing the production, maintenance, and distribution of clean plants, 2) Advancing special initiatives by optimizing the adaptation and implementation of novel technologies and new ideas while increasing the awareness of the importance, availability, and use of clean plants, and 3) Optimizing network resources. Applicants should refer to the NCPN Request for Proposals on the USDA APHIS NCPN website for additional details. APHIS is providing at least $10 million in funding for the Plant Protection Act (PPA) National Clean Plant Network (NCPN) program under Section 420 of the PPA (7 USC § 7721). The purpose of the NCPN program is to establish a network of Clean Plant Centers for diagnostic and pathogen elimination services to produce clean propagative plant material and to maintain blocks of pathogen-tested plant material in sites located throughout the United States. Additional details about the program are available on the USDA APHIS NCPN website. Program Goals: The National Clean Plant Network (NCPN) was established under The Food, Conservation and Energy Act of 2008 (Farm Bill) Title X, Sec 10202. Its purpose is to support a network of clean plant centers in the United States for specialty crops to provide reliable sources of propagative material that are free of targeted propagative-borne pathogens. Network clean plant centers conduct diagnostic and pathogen elimination services and establish foundation blocks (nuclear stock) to provide pathogen-tested plant materials to nurseries, growers, and to state certification programs.  Expected Outcomes: Projects funded under this announcement are expected to support programs that provide propagative plant material free of targeted plant pathogens to protect the environment and ensure the global competitiveness of U.S. specialty crop producers. Funding Priorities: APHIS will consider project proposals that clearly and directly support the strategic goals and objectives of the National Clean Plant Network. Program priorities align with the goals specified in the NCPN Strategic Plan and include: 1) Optimizing the production, maintenance, and distribution of clean plants, 2) Advancing special initiatives by optimizing the adaptation and implementation of novel technologies and new ideas while increasing the awareness of the importance, availability, and use of clean plants, and 3) Optimizing network resources. Projects that support one of the current crop groups in NCPN and show coordination with the appropriate NCPN specialty crop governing body are prioritized for funding. Existing Federal or State facilities with demonstrated capacity to provide clean plant material are also prioritized for funding. Applicants can find all application materials on the ezFedGrants website or the Grants.gov website by searching Assistance Listing number 10.031 . Application materials and additional i nformation are also available on the USDA APHIS NCPN website . All application materials are compliant with Section 508 of the Rehabilitation Act of 1973 for accessibility.

The purpose of the Feral Swine Eradication and Control Project (FSCP) is to respond to the threat feral swine pose to agriculture, native ecosystems, and human and animal health. Feral swine are a destructive, non-native, invasive species and their populations have expanded across the United States since the 1980’s. Over an estimated $3.4 billion in damage, including agricultural, is caused by feral swine each year. The species can have significant negative impacts on plant and animal habitats, soils, water quality, as well as other natural and cultural resources. Livestock and humans are also susceptible to diseases carried by feral swine. The Agriculture Improvement Act of 2018 directs the United States Department of Agriculture (USDA) to carry out the pilot program where the Secretary has determined that feral swine have been identified as such a threat and the One Big Beautiful Bill Act extended this authority. FSCP funding will be available for projects identified by USDA in conjunction with State Technical Committees in states determined by the Animal and Plant Health Inspection Service (APHIS) Wildlife Services as having high feral swine densities. Please visit the Feral Swine Eradication and Control Pilot Program webpage (https://www.nrcs.usda.gov/feral-swine-eradication-and-control-pilot-program) to find the proposed pilot projects looking for applicants. Additional information about proposed pilot project activities in the following states Alabama, Arkansas, California, Florida, Georgia, Hawaii, Louisiana, Mississippi, Missouri, North Carolina, Oklahoma, South Carolina, Tennessee, and Texas will also be available on the webpage. Pilot projects will consist broadly of three coordinated components: 1) feral swine removal by APHIS, 2) restoration efforts supported by NRCS or non-federal partner, and 3) assistance to producers for feral swine control provided through grants with non-federal partners. This call for proposals is intended to address component 2 and component 3 described above for non-federal partners to provide landowner assistance for restoration and/or on-farm trapping efforts and provide related services as part of the pilot projects described above. Funding for these services will be provided through grant agreements between partners and NRCS. All projects will be a collaborative and coordinated effort between the selected partner, NRCS, and APHIS. It is required that APHIS maintains operational control of feral swine management activities. A webinar for NRCS' Feral Swine Eradication and Control Pilot Program 2026 is scheduled for July 29, 2026 3-4 p.m. Eastern Time and August 20, 2026 3-4 p.m. Eastern Time.

The Meat and Poultry Processing Expansion Program (MPPEP) provides grants to help eligible meat and poultry processors expand their capacity, which creates new, better and more processing options for meat and poultry producers. The goal for MPPEP Phase 3 Round 2 is to support Processors of Invasive, Wild-Caught Catfish species by increasing Processing capacity and providing greater opportunity in this sector. Strategies that can fulfill the goal of this NOFO and ensure lasting impacts include projects to increase Processing capacity; increase Processing volume; elevate incomes for both fishers and Processors; and to provide fair wages, and new, stable and safe job opportunities at Processing facilities to increase economic development in rural communities.

The U.S. Department of Agriculture (USDA), Agricultural Marketing Service (AMS), requests applications for the fiscal year (FY) 2026 Specialty Crop Multi-State Grant Program (SCMP). The SCMP supports collaborative multi-state partnerships to enhance the competitiveness of specialty crops through competitively funded projects. A multi-state partnership is a project that implements activities with measurable outcomes that benefit two or more U.S. States and/or Territories along with non-profit entities. The focus is to address regional or national level specialty crop issues, including, but not limited to, food safety, plant pests and disease, research, crop-specific projects addressing common issues, and marketing and promotion. Projects must enhance the competitiveness of U.S. or U.S. territory-grown specialty crops in either domestic or foreign markets.

This funding opportunity is provided to carry out the provisions described in Section 7721 of the Plant Protection Act . Through the PPA 7721 program, APHIS provides funds to support projects that protect specialty crops, nursery systems, forestry, other agricultural production systems, and natural resources from harmful and invasive plant pests and pathogens. Additional details about the program are available on the PPDMDPP website. APHIS will make available up to $90,000,000 in funds to support PPA 7721 projects in Fiscal Year 2027 (FY 2027), with at least $73 million anticipated to be available for PPA 7721 PPDMDPP. APHIS will consider suggestions that clearly and directly support the objectives and strategies within the six PPDMDPP goal areas . Suggesters should refer to the FY 2027 PPA 7721 Implementation Plan , for details about the strategies and objectives for each goal area. Program Objectives: PPDMDPP funds projects focused on critical needs and opportunities to prevent against, detect, and mitigate invasive plant pests and diseases. PPDMDPP projects are organized around six goal areas: Plant Pest and Disease Survey and Analysis Domestic Inspection Pest Identification and Diagnostic Technology Protecting Nursery Production Public Outreach and Education Pest Mitigation and Rapid Response Expected Outcomes: Projects funded under this announcement are expected to support activities that will protect U.S. specialty crops, nursery systems, forestry, and other agricultural production and natural resources from harmful and exotic plant pests and pathogens by improving early plant pest detection, threat identification, and mitigation capabilities. Funding Priorities: PPA 7721’s PPDMDPP funds projects focused on critical needs and opportunities to prevent against, detect, and mitigate invasive plant pests and diseases organized around six goal areas. These six goal areas represent the Program’s funding priorities and include: enhancing plant pest and disease survey and analysis; targeting domestic inspection; enhancing and strengthening pest identification and technology; safeguarding nursery production; conducting targeted outreach and education; and enhancing mitigation and rapid response capabilities (see FY 2027 Implementation Plan ). Suggesters must complete a single PPA 7721 ServiceNow Suggestion Submission form per suggestion that provides details on all aspects of the project. The PPA 7721 ServiceNow Suggestion Submission form is available through the PPA 7721 ServiceNow Suggestion Submission portal. Suggesters must include a completed Budget, Survey, or Diagnostic Laboratory template, and Narrative Report (if applicable) as an uploaded document with the form. Refer to the PPA 7721 ServiceNow Suggestion Submission Guidance for more information about submitting suggestions to the PPA 7721 ServiceNow Suggestion Submission portal.

The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. The purpose of this Notice of Funding Opportunity is to establish the GREGoRi Technology Integration Center, which will enable the development of standards and best practices for applying new and emerging molecular methods in rare disease diagnosis. A major deliverable of the Center will be a multidimensional dataset that can be used for the development and benchmarking of novel tools and strategies that facilitate rare disease diagnosis.

The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. The purpose of this Notice of Funding Opportunity is to establish the GREGoRi Data Coordination and Outreach Center. The Data Coordination and Outreach Center will act as the central point of coordination for the GREGoRi Research Program, and will be responsible for ensuring that the protocols, data, metadata, computational tools and other resources developed as part of GREGoRi are made available to the broader research community.

The overarching goal of this notice of funding opportunity (NOFO) and its companion opportunities is to establish the Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) Program to support development of innovative, reliable, cost-effective, and sustainable multimodal AI-based clinical decision support (CDS) tools. PRIMED-AI CDS tools are based on the integration of clinical imaging with other types of multimodal health data to enhance care for patients with a wide range of health conditions. The PRIMED-AI Program seeks to catalyze the adoption of AI-based CDS tools into clinical workflows to enable novel personalized medicine strategies that address significant health challenges. The purpose of this NOFO is to solicit applications for the creation of a Validation Center to serve as a dedicated hub for the comprehensive evaluation and characterization of AI-enabled, image-based, multimodal CDS tools developed by the PRIMED-AI Consortium, to ensure these tools are reliable, reproducible, and generalizable. The Validation Center will focus on verification, validation, interoperability, and uncertainty quantification to comprehensively characterize performance of the CDS tools developed by the program. The core functions of the Validation Center will involve the systematic validation of PRIMED-AI Consortium deliverables, including those emerging from award recipients under the Playbook, Data-to-Model Academic-Industrial Partnerships, and Model-to-Clinic NOFOs.

This Notice of Funding Opportunity (NOFO) invites applications for advanced development and enhancement of emerging informatics technologies to improve the acquisition, analysis, visualization, and interpretation of data across the cancer research continuum including cancer biology, cancer treatment and diagnosis, early cancer detection, risk assessment and prevention, cancer control and epidemiology. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Program, this NOFO is focused on advancing emerging informatics technology, defined as one that has passed the initial prototyping and pilot development stage, has demonstrated potential to have a significant and broader impact, has compelling reasons for further improvement and enhancement, and has not been widely adopted in the cancer research field. To be successful, proposed development plans must have a clear rationale for why the proposed technology is needed and how it will benefit the cancer research field. In addition, mechanisms to solicit feedback from driving cancer research projects as well as the broader user community throughout the development process must be included.This NOFO invites applications for the enhancement and dissemination of emerging, user-friendly informatics technologies that support a wide range of cancer research, including discovery biology, population studies, as well as clinical and translational research. The emphasis is on uniqueness and potential impact on cancer research. In addition, all projects proposed in response to this NOFO must involve the following general attributes:Potential to advance driving cancer research projects and the cancer research field in general;Offers clear advantages over competing technologies in the targeted cancer research domain;Provides compelling plans and processes for supporting and engaging end users to evaluate and apply the tool or resource;Provides plans for advancing use of the tool or resource by the targeted community through collaboration, outreach, and training;Provides a realistic timeline and milestones for technology development.