Alternatives to Pilot access schemes to Technology Infrastructures for European startups, scaleups and innovative SMEs (CSA)

Expected Outcome: This action aims to establish European leadership in neutral-atom quantum simulation and digital quantum computing by delivering: Fully programmable industry-ready quantum simulators based on 10.000 neutral atoms in a scalable architecture, accessible via cloud platforms, and with the possibility of integrating them into high-performance computing environments. Fully programmable platform for neutral-atom quantum computing capable of both analogue quantum operations and gate-based computing with 1.000 physical qubits and a clear path to further scalability to 10.000 physical qubits. Coherence time of the order of hundreds of interaction times and infidelity of operations below 1%. Demonstration of quantum simulation and/or computing operating beyond classical computability, validated through benchmarking with classical methods. New real-world applications across science and industry (at least two) (e.g: in the energy and health sectors) The software stack for these applications, including enhanced software for verification, algorithm implementation, and user programming interfaces. Demonstration of the full quantum stack – including quantum control, electronic…

Expected Impact: This Challenge looks to accelerate the development and uptake of clinically validated interventions that target the root cause of multiple age-related morbidities. It will: Deliver biotechnology-based interventions for healthy ageing Accelerate the implementation of personalised care in ageing based on molecular phenotyping​ Provide recommendations for regulatory pathways addressing ageing as a target to inform developers, regulators, and other decision makers​, and Improve citizen literacy on longevity. Expected Outcome: Ambitious proposals put forward under this call will deliver: Proof-of-concepts (TRL3 completed) of biotechnology-based or pharmaceutical interventions that prevents or delays the onset of, or reverts, an age-related disease in a vertebrate model system, based on the hallmarks of ageing, taking into consideration practical challenges of implementing such an intervention Tools to facilitate development or adoption of the interventions above, such as proof-of-concept validation of biomarker signatures or suitable pre-clinical models​, and Approaches to address the shared regulatory hurdles and societal challenges linked to ageing-related…

Expected Outcome: Proposals are expected to contribute to all of the following expected outcomes: stakeholders are empowered to co-create, deploy and replicate viable ecosystem restoration measures leading to their wider uptake, with solutions to address implementation bottlenecks and financing issues; competent authorities in charge of implementing the EU Nature Restoration Regulation (NRR) can design and reuse effective deployment frameworks, informed by evidence and lessons generated through living labs across different contexts; social, economic and environmental co-benefits, risks and trade-offs of nature restoration activities are demonstrated, addressed and made explicit to support informed decision-making and scaling, including, where appropriate, potential One Health aspects. Scope: The NRR requires Member States to put in place area-based restoration measures, including Nature-based solutions, as highlighted and recommended in both the EU Climate adaptation strategy and in the European Water Resilience Strategy. Notably measures to implement the NRR article 9 on free-flowing rivers support the objectives of the European Water Resilience Strategy to restore and protect…

Expected Outcome: Proposals are expected to contribute to all the following expected outcomes: custom officers, border guards and relevant law enforcement officers and civil servants from competent authorities have improved capacities to detect illegal wildlife trade and prevent invasive alien species introduction, reintroduction and spread; illegal wildlife trade is better detected, contributing to improved protection of endangered species, and the spread of invasive alien species through trade is prevented and identified as early as possible, supporting the EU and global biodiversity objectives. Scope: Wildlife trafficking and invasive alien species pose major threats to biodiversity [1] and present important challenges regarding enforcement, prevention and detection capacities. Invasive alien species also cause significant negative economic impacts, estimated at around €12 billion per year in the EU, and wildlife trafficking is one of the most profitable criminal activities worldwide [2] . Moreover, they pose significant health hazards. The rate of introduction of invasive alien species has been increasing. Wildlife trafficking is also increasing, especially due to increase in…

Expected Outcome: Proposals are expected to contribute to all the following expected outcomes: the mechanistic understanding of PFAS (per- and polyfluoroalkyl substances) effects on biodiversity, on ecosystems and on ecosystem services is improved and evaluations of their extent are available; research needs to close knowledge gaps and to address issues on biodiversity and ecosystem services are better identified; the new knowledge can be integrated by policymakers in their decisions related to biodiversity protection and restoration, environmental protection and protection of human health as well as in socio-economic cost-benefit analysis for policy measures on PFAS. Scope: PFAS pollution significantly impacts human health and the environment. Addressing PFAS is notably a flagship action under the Water Resilience Strategy [1] . There is growing evidence on impacts on biodiversity above and below ground and water, but more evidence is needed to substantiate the effects on different species, populations and entire ecosystems, and their extent. A European Commission study published on 29 January 2026 [2] revealed significant knowledge gaps on the effects of PFAS on biodiversity. In…

Expected Outcome: Increased recovery rates of valuable raw materials, particularly critical raw materials from low grade or complex ores and/or from mining waste; Increased economic performance in terms of higher material-, water-, energy- and cost-efficiency and flexibility in minerals processing and metallurgical processes; and Improved health, safety and environmental performance of the operations throughout the whole life cycle that is considered, including a reduction in waste, wastewater and generation of emissions of air pollutants and a better recovery of resources from generated waste, reducing the environmental footprint and contributing to biodiversity and ecosystems preservation. Scope: Actions should develop and validate / demonstrate pilot scale facility located in the EU integrating relevant processing and refining technologies for improved recovery of raw materials from low grade and/or complex ores from extractive wastes, reduction of waste and water and air pollution, higher energy efficiency and reduction of land and sea-use change, habitat loss, degradation and fragmentation. The action can also focus on reducing the content of toxic elements or compounds in…

Expected Outcome: Proposals are expected to contribute to all the following expected outcomes, in full alignment with the OceanEye initiative: scientists, public authorities and businesses benefit from strengthened and resilient global ocean observing capacities, coordinated under the Intergovernmental Oceanographic Commission’s Global Ocean Observing System (GOOS), [1] through the deployment of ocean observation equipment, in particular for the provision of critical observations for marine biodiversity and ecosystem knowledge; public authorities prioritise investments on infrastructures and capacity building to advance ocean research, protect and restore ocean health and biodiversity and provide critical services through a global ocean observing system and data delivery that is fit-for purpose, cost efficient and designed across all its components; increased EU leadership and strategic autonomy in global ocean observation capabilities, in support of EU climate and biodiversity goals, strengthening the EU’s contribution to and influence within GOOS, and reducing the risk of critical dependencies, notably for key services (i.e. Copernicus Services); enhanced collaboration between…

Expected Outcome: Project results are expected to contribute to some or all of the following outcomes: Critical infrastructure operators and authorities have access to efficient, adaptable, resilient and reliable tools and processes enabling or improving virtual and physical stress tests of their respective assets/ and operations; Critical entities have broader and deeper understanding of their technical and operational vulnerabilities and adaptive capabilities, improving the scenario building and stress tests exercises; Systems allowing notification and collaboration under stress conditions are available for relevant stakeholders; Critical entities are better equipped for post-incident investigations, including data collection, analysis and improved learning, management and sharing in a secure manner; Improved operational procedures including incidents management and training curricula are developed. Scope: The resilience of critical entities is of paramount importance as disruptions to these systems can have significant consequences for the whole economy, public health, security or safety. These systems, responsible for providing essential services for modern society, are…

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes: Housing-led approaches [1] aligned with the NEB are made available to stakeholders involved in tackling homelessness [1] . Robust evidence on NEB-aligned housing-led approaches tackling homelessness (including people temporarily hosted by acquaintances and family) to inform the development and/or update of policies and services for prevention and early intervention in the context of the green transition [1] in neighbourhoods [1] . Scope: Social and affordable housing is being advanced in the EU, including through the Affordable Housing Initiative [5] . Despite efforts, current policies for the green transition are failing to adequately address the housing crisis. Homelessness remains a structural challenge across Europe, with negative impacts on both individuals experiencing it (e.g. physical and mental health, social and economic conditions) and neighbourhood communities [1] (e.g. pressure on public services, erosion of social fabric [1] , etc.). Research and innovation gaps in tackling homelessness range from data collection (i.e. the variety of approaches to defining,…

Expected Outcome: Increased economically viable and functionally equivalent renewable material and sustainable chemical solutions used in large scale textile applications, including apparel, home and technical textiles; A realistic pathway for an absolute reduction of the use of virgin fossil-based materials and chemicals used to produce textile products for the EU market by 2035, contributing to enhance the preservation of human health, biodiversity and ecosystems, whether aquatic or terrestrial ecosystem preservation and emission reduction; Uptake of business models and system approaches that allow for the scale up of sustainable textile material and chemical alternatives as competitive alternatives to conventional approaches. Scope: Innovative renewable textile fibres and sustainable chemical solutions today face almost insurmountable cost disadvantages compared to extremely cost-competitive and industrially entrenched fibres and chemicals based on virgin fossil resources. To allow for the scale up of the use of innovative renewable materials and sustainable chemicals by the textile industry, improved processability of materials, suitable processing technology, deeper technical…

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes: Robust evidence on how inhabitants experience their neighbourhood [1] and the impact of these experiences on their health and well-being. The research informs policies, strategies, neighbourhood planning and procurement for the green transition [1] of neighbourhoods, including their nature-positive [3] transformation and climate resilience. Scope: Neighbourhoods are human-social constructs and environments. They are shaped by complex inter-connections and interdependencies of human and non-human actors in the natural and built environment [1] they comprise. An increasing body of research is looking at the relationship between people and the built environment, from neuro-architectural aspects of space to atmosphere and ambiance aspects in urban design and planning, influencing also the perception of beauty. Digitalisation is also allowing to understand, map and enhance how inhabitants experience the built environment. Yet, more evidence is needed on how inhabitants react to and identify with their neighbourhoods as well as the effects of these experiences on their physical and…

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes: Creation of cutting-edge tools, processes, equipment and technologies to enhance disaster and emergency response capabilities for various practitioners as well as for assets, such as vehicles, aircraft, and heavy equipment; Taking into consideration existing technologies, development of autonomous drones, robotics, and other technologies specifically designed for emergency medical response and search and rescue operations in hazardous conditions such as wildfires, earthquakes and large-scale events; Improvement of response efficiency and safety for survivors and emergency practitioners through the adoption of advanced, technology-driven solutions in disaster scenarios; Consider needs of existing EU-level capacities, emergency reserves, and stockpiling in the deployment of the assets and being able to move them. Scope: The scope of this topic is the development of innovative tools, equipment, and technologies to enhance the capabilities of emergency responders operating in complex and hazardous disaster environments. By leveraging advancements in smart protective…