Research grants & funding

Modification 000002: Updated Appendix A and the definition of “Construction and demolition waste”, also denoted as “C&D Waste”, to align with the programmatic authorizing statute for the Alternative Fuels and Feedstocks Office listed in NOFO Part 1, Section III.G. Statutory Authority. • “Construction and demolition waste,” for the purposes of this NOFO and consistent with the statutory authorities1, refers to waste organic materials from buildings, roads and bridges, and other sectors, but not included in municipal solid waste. It includes wood waste materials, including waste pallets, crates, dunnage, manufacturing and construction wood wastes (other than pressure-treated, chemically-treated, or painted wood wastes), and landscape or right-of-way tree trimmings. Updated Section III.D. Key Requirements and Section III.F. Applications Specifically Not of Interest to specify that target chemicals should have global annual markets or potential markets of at least 1 million metric tons. • Previously this metric was given as U.S. production of at least 1 million metric tons. Modification 000001: Moved the application content requirement for Letter(s) of Commitment (LOCs) from Stage 2 to Stage 1. • Added a clause in Section III.D indicating that LOCs are to be submitted with Stage 1 applications. • Updated the summary table in Section IV.D.2 to reflect the above (added Stage 1 LOC requirement) • Updated the summary table in Section IV.E.1 to reflect the above (added “(as needed, in addition to Stage 1 submittals)”). DOE CMEI is dedicated to securing America’s energy future by reinforcing domestic critical mineral supply chains, driving next-generation energy technology and manufacturing research, and promoting affordable, consumer-friendly solutions. CMEI’s AFFO is issuing this ASPECT NOFO, DE-FOA-0003647, to support research, development, and pre-pilot testing of innovative technologies that produce chemicals from alternative and waste feedstocks, mobilizing America’s abundant alternative feedstocks resources. The goal of this Notice of Funding Opportunity (NOFO) is to advance promising chemical technologies that utilize alternative feedstocks through multiple levels of maturity and, in some cases, to pre-pilot scale. To accomplish this, the NOFO is divided into two topic areas, each divided into two subtopic areas designed to provide different on-ramps for technologies at different stages of development. Topic Area 1 supports the progression of technologies in the R&D phase. Subtopic Area 1a supports advancing early-stage research to bench scale. Subtopic Area 1b is intended to move projects closer to pre-pilot scale, to a point where critical unit operations must be further developed and demonstrated. Topic Area 2 provides an on-ramp for technologies ready to move from R&D to full pre-pilot scale and operations. Projects applying to Topic Area 2 should aim to advance their technology to design, construct, and operate pre-pilot scale facilities. Both subtopic areas have the same goal—to move technologies into integrated pre-pilot systems and operate them—but allow for two different points of entry. Subtopic Area 2a targets preliminary pre-pilot scale testing of critical unit operations before engineering and design can commence for the entire system while Subtopic Area 2b projects will involve technologies that are ready for design and construction of an integrated pre-pilot facility. Please see the full NOFO document at eere-exchange.energy.gov. Questions regarding the NOFO must be submitted to ASPECT@doe.gov. The required Concept Paper due date for this NOFO is 10/09/2026 at 5PM ET. The Full Application due date for this NOFO is 12/01/2026 at 5PM ET. As stated in the Notice of Intent (search DE-FOA-0003646 in eXCHANGE), a Teaming Partner List has been compiled to encourage collaboration and facilitate the formation of new project teams. Visit: TPL-0000073 Teaming Partner List for DE-FOA-0003646 NOI to Publish DE-FOA-0003647 The eXCHANGE system is currently designed to enforce hard deadlines for Concept Paper and Full Application submissions. The APPLY and SUBMIT buttons automatically disable at the defined submission deadlines. The intention of this design is to consistently enforce a standard deadline for all applicants. Applicants that experience issues with submissions PRIOR to the NOFO Deadline: In the event that an Applicant experiences technical difficulties with a submission, the Applicant should contact the eXCHANGE helpdesk for assistance (exchangehelp@hq.doe.gov). The eXCHANGE helpdesk and/or the EERE eXCHANGE System Administrators (eXCHANGE@ee.doe.gov) will assist the Applicant in resolving all issues. Applicants that experience issues with submissions that result in a late submission: In the event that an Applicant experiences technical difficulties with a submission that results in a late submission, the Applicant should contact the eXCHANGE helpdesk for assistance (exchangehelp@hq.doe.gov). The eXCHANGE helpdesk and/or the EERE eXCHANGE System Administrators (eXCHANGE@ee.doe.gov) will assist the Applicant in resolving all issues (including finalizing the submission on behalf of, and with the Applicant's concurrence). DOE will only accept late applications when the Applicant has a) encountered technical difficulties beyond their control; b) has contacted the eXCHANGE helpdesk for assistance; and c) has submitted the application through eXCHANGE within 24 hours of the NOFO's posted deadline.

Expected Outcome: This action aims to establish European leadership in neutral-atom quantum simulation and digital quantum computing by delivering: Fully programmable industry-ready quantum simulators based on 10.000 neutral atoms in a scalable architecture, accessible via cloud platforms, and with the possibility of integrating them into high-performance computing environments. Fully programmable platform for neutral-atom quantum computing capable of both analogue quantum operations and gate-based computing with 1.000 physical qubits and a clear path to further scalability to 10.000 physical qubits. Coherence time of the order of hundreds of interaction times and infidelity of operations below 1%. Demonstration of quantum simulation and/or computing operating beyond classical computability, validated through benchmarking with classical methods. New real-world applications across science and industry (at least two) (e.g: in the energy and health sectors) The software stack for these applications, including enhanced software for verification, algorithm implementation, and user programming interfaces. Demonstration of the full quantum stack – including quantum control, electronic…

Silicon Carbide Cladding Lead Test Rod Development-Phase 1Research, development, and fabrication of Silicon Carbide cladding specimens for research reactor insertion, irradiation, and post-irradiation examinations by 2030. The objective of this program is to advance the scientific and technological maturity of silicon carbide cladding for nuclear fuel rods for future use in commercial light water reactors.

Expected Outcome: This action will advance Europe’s leadership in trapped-ion quantum computing by achieving the following key outcomes: Establishment of a full-stack ion-trap quantum computer aiming at more than 1.000 qubits, fully integrated into high-performance computing (HPC) systems, and accessible via the cloud. Demonstration of quantum advantage for selected real-world applications, validated against benchmarks. Strengthened European capabilities to develop modular, interoperable, and scalable quantum computing architectures. Implementation and demonstration of advanced error correction and fault-tolerant quantum computing techniques. Integration of full-stack hardware-software systems with standardised and certified interfaces. Engagement with industry and academia through open access to quantum computing resources and co-design of applications. Scope: The action should support the scale-up of European trapped-ion quantum computing platforms, aiming at technological maturity and usability for industrial and scientific applications. In particular, the action must address at least two major technical roadblocks defined in the Strategic Research and Industry Agenda (SRIA…

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes: Public authorities, industry, technology providers, energy producers and consumers profit from de-risking of cost-effective essential value chains of those renewable fuel technologies that can contribute to domestic commercial fuel production beyond 2030 customized to their needs, from improved access to better financing exploiting synergies across funding schemes, and from more effective market uptake, business models, increased competitiveness, and commercialization opportunities. Energy producers, clean tech manufacturing industries, researchers and consumers benefit from improved performance, lower environmental impact, security and competitiveness of ad-hoc renewable fuel technologies compared to existing ones, as well as new market opportunities. Community, public authorities and industry benefit from sharing the de-risking cost and reducing it by engaging several competing solution suppliers/technology providers in parallel, boosting transnational public and private investments in de-risking and attracting new players to tackle supplier lock-in issues The implementation…

Expected Outcome: This action will strengthen Europe's strategic autonomy in quantum-secure communications by advancing core QKD technologies and integration capabilities. Expected results include: Development and demonstration of next-generation QKD systems, with a focus on cost-effectiveness and integration, with specific measurable improvements in one of the following parameters or features: (i) key rate (>1 Mbps over metropolitan distances), (ii) operational coverage of a network at the regional scale, >300 km for fibre-based QKD, including e.g. twin field and free-space links also for non-wired segments and for redundancy, (iii) development and demonstration of advanced quantum cryptographic protocols beyond QKD with provable security advantage over classical cryptographic systems. Implementation of hybrid quantum-classical cryptographic frameworks combining QKD and post-quantum cryptography (PQC), tested on clearly defined real-world applications. Integration of quantum communication components with network equipment and orchestration systems (e.g., software-defined networking). Validation of QKD-based security in high-priority use cases beyond EuroQCI infrastructure,…

Expected Outcome: This action will strengthen Europe's leadership and strategic autonomy in quantum technologies by advancing experimental pilot line capacities as a vital stepping stone toward future industrial-scale quantum hardware production. Qu-Pilot serves as the critical intermediary between academic research and the stable pilot lines under the Chips Joint Undertaking, offering a testbed for technological innovation, reproducibility, and manufacturability. Expected outcomes include: Deployment of experimental quantum pilot lines addressing diverse platforms and materials, laying the groundwork for broader integration into Chips JU pilot lines. Establishment of scalable and reproducible quantum fabrication processes, advancing TRL 4–6 technologies and addressing early-stage certification, standardisation, and quality control. Reinforcement of a pan-European quantum hardware ecosystem through shared infrastructure and open-access models, fostering participation from SMEs, startups, and research institutes. Demonstrated ability to accelerate technology maturity and feed critical feedback loops into future Chips JU stability pilot lines. Enhanced synergies with testing…

Expected Outcome: This action will consolidate Europe’s position in superconducting quantum computing through: Establishment of a full-stack superconducting quantum computer aiming at 1.000 physical qubits and QPU architecture based on chiplet technology. The system should feature a scalable and user-adjustable architecture, T1 coherence time above 100 us, gate fidelities (both one- and two-qubit gates, and read-out) of at least 99.9%, read-out speed below 300 ns, two-qubit gate speed below 20 ns. Demonstration of quantum advantage on selected industrial use cases, validated through benchmarking with best-in-class classical methods. Deployment of a cloud-accessible quantum system integrated with high-performance computing environments. Maturation of fault-tolerant quantum computing protocols, including effective quantum error correction and noise mitigation schemes. Delivery of a comprehensive, standardised software stack supporting system bring-up, calibration, control, benchmarking, and user access. Strengthened supply chains and industrial capacity in Europe for superconducting quantum technologies. Scope: The proposal should contribute to the scale-up and practical deployment…

Expected Outcome: This action will establish a pan-European open-access testing and experimentation infrastructure for quantum technologies, enabling systematic validation and certification of quantum components and systems. Expected outcomes include: Deployment of distributed quantum testing facilities accessible across Europe, including remote access and standardized test protocols. Provision of certification services aligned with future standardisation efforts, ensuring trust, quality, and interoperability of quantum technologies. Support for SMEs, start-ups, and research institutions in validating quantum components and sub-systems. Strengthening of Europe’s competitiveness by ensuring robust quality assurance mechanisms and accelerating the time-to-market of emerging quantum products. Scope: The proposal should implement the testing-related part of the action plan established under the Framework Partnership Agreement for Qu-Test. The action must include: Expansion and interconnection of open-access testing facilities in multiple Member States, covering a range of quantum technologies (e.g., processors, sensors, photonics, control systems). Development and deployment of…

Treasury is publishing multiple funding opportunity notices for its RESTORE Act grant programs. This announcement applies only to the Centers of Excellence Research Grants Program.Trust Fund amounts are available to establish one or more Centers of Excellence through competitive subawards to nongovernmental entities and consortia in the Gulf Coast Region, including institutions of higher education. Funds may be used to establish Centers of Excellence, and by those Centers of Excellence for science, technology, and monitoring in one or more of the following disciplines as described in the RESTORE Act and Treasury’s implementing regulations at 31 CFR 34.704: 1) Coastal and deltaic sustainability, restoration, and protection, including solutions and technology that allow citizens to live in a safe and sustainable manner in a coastal delta in the Gulf Coast Region. 2) Coastal fisheries and wildlife ecosystem research and monitoring in the Gulf Coast Region. 3) Offshore energy development, including research and technology to improve the sustainable and safe development of energy resources in the Gulf of Mexico. 4) Sustainable and resilient growth, economic and commercial development in the Gulf Coast Region. 5) Comprehensive observation, monitoring, and mapping of the Gulf of Mexico.Eligible applicants issuing subawards to Center(s) of Excellence must establish and implement a program to monitor compliance with its subaward agreements.

Silcon Carbide Cladding Lead Test Rod Development-Phase 1 Research, development, and fabrication of Silicon Carbide cladding specimens for research reactor insertion, irradiation, and post-irradiation examinations by 2030. The objective of this program is to advance the scientific and technological maturity of silicon carbide cladding for nuclear fuel rods for future use in commercial light water reactors.

NIOSH is encouraging the submission of an application from qualified organizations for a National Center for Construction Safety and Health Research and Translation. Applicants are encouraged to propose multidisciplinary approaches and coordination for impactful applied and intervention research, hazard identification, and controls; develop partnerships for implementing prevention and intervention activities; and serve as a leader in research translation and research-to-practice for the protection of construction workers in the U.S. The Center will accomplish these goals by integrating and advancing research, research translation, best practices, policy and guidance, and capacity building. Center work should consider the NIOSH strategic plan and NORA construction research objectives. Center structure should take advantage of diverse scientific resources and focus on national worker safety and health issues. Centers should emphasize the creation and implementation of evidence-based solutions that address important construction industry safety and health problems. Collaborations with other academic institutions, nonprofit organizations, and other occupational safety and health-focused groups are expected. Applicants must concisely describe the occupational health burden of important safety and health issues in the construction industry and discuss how focused research and outreach activities will help alleviate the burden and reduce numbers. Applicants should also clearly articulate the anticipated impacts of the Center’s proposed work, both during the project period and beyond.

This is a notice of funding opportunity (NOFO) for NIJ FY 2026 Research and Evaluation on School Safety. This opportunity will support rigorous research and evaluation projects to fill key gaps regarding K-12 safety, specifically focusing on the development, deployment, and operation of: • Anonymous reporting systems for threats of school violence, including mobile telephone applications, hotlines, and internet websites • School threat assessment and intervention teams that include coordination with law enforcement agencies and school personnel This NOFO seeks rigorous outcome/impact evaluations paired with process/implementation evaluations to assess the effectiveness of activities supported by STOP1 School Violence Act (SVA) projects administered by the Bureau of Justice Assistance (BJA) and the Office of Community Oriented Policing Services (COPS Office) School Violence Prevention Program (SVPP) or similar programs from other sources that align with STOP SVA's goals. To develop practical recommendations for K-12 school safety, applicants are strongly encouraged to work closely with educators, school stakeholders, and communities to develop questions, identify solutions, collect data, and interpret findings. Applicants should: • Clearly describe complex factors and how they will be measured. • Include letters of support confirming secondary data access and explain how datasets will be matched to support the analyses proposed. • Describe data limitations, how they will be addressed, and their potential impact on findings.

Expected Outcome: Deep sedimentary/basement reservoirs are usually characterized by low permeability, high drilling cost and a scarcity of data, as they are typically ignored by hydrocarbon exploration. Major exploration challenges relate to predicting deep sedimentary and basement reservoir structures and properties to identify suitable locations for reservoir-independent approaches, capable of overcoming the low permeability obstacle, such as Enhanced Geothermal Systems (EGS) or closed-loop geothermal systems. Project results are expected to contribute to all of the following expected outcomes: Increased knowledge base for developers to unlock unexploited geothermal resources, increase drilling success rate, increase geothermal sources performance and reduce the risk of induced seismicity and deploy geothermal energy in a sustainable way in environmental (notably on biodiversity and pollution) and socioeconomic terms. Citizens and local communities are engaged and benefit from local, more secure and affordable renewable energy sources. Scope: Advanced methods, technologies and conceptual models, for different geological settings, to identify suitable conditions for geothermal…

This is a notice of funding opportunity (NOFO) for the NIJ FY 2026 Evaluation of the Effectiveness of the Bureau of Justice Assistance (BJA) Byrne State Crisis Intervention Program (SCIP).1 This opportunity will support research and evaluation to assess the effectiveness of programs funded under FYs 2022-2026 BJA’s Byrne SCIP NOFOs. BJA’s Byrne SCIP provides funding for the creation or enhancement of state crisis intervention court proceedings and related programs or initiatives, including extreme risk protection order (ERPO) programs, as well as mental health courts, drug courts, and veterans treatment courts. Such programs or initiatives can include, but are not limited to: 1) Law enforcement crisis interventions; 2) Court-based programming; 3) Referrals to treatment for people in crisis; and 4) ERPO programs. Applicants may apply to assess multiple program areas where applicable. NIJ anticipates making at least one award per topic area for a total of 4 awards. Applicants should clearly state the program area(s) on the title page. This NOFO invites applications proposing a two-phased evaluation strategy to assess Byrne SCIP. The approach includes: • Phase I: Evaluability Assessments. • Phase II: An Evaluation of the Byrne SCIP’s Effectiveness. Applications to this NOFO should include both phases. Applications that do not meet this requirement would not be considered responsive to this funding opportunity.

The Department of Defense (DoD) announces the Fiscal Year 2027 Defense University Research Instrumentation Program (DURIP). DURIP is designed to improve the capabilities of accredited United States (U.S.) institutions of higher education to conduct research and to educate scientists and engineers in areas important to national defense, by providing funds for the acquisition of research equipment or instrumentation. For-profit organizations are not eligible for DURIP funding.

The opportunities associated with this NOFO are for lands protected through the Wetland Reserve Easements (WRE) component of the Agricultural Conservation Easement Program (ACEP) and the Floodplain Easement (FPE) component of the Emergency Watershed Protection Program (EWPP). The types of work available through this opportunity fall into three primary categories: 1) restoration of wetland and floodplain easements; 2) stewardship of wetland and floodplain easements, and 3) onsite and offsite assessment of easement conditions.  Component 1) Wetland and Floodplain Easement Restoration.  Awardees will work with NRCS personnel, partners and landowners to develop and implement sound easement restoration plans. These plans may include structural practices, such as levees and water control structures, and/or vegetative establishment practices, such as tree planting. Awardees are expected to complete the following easement restoration activities: (A) Coordination- Accept input on restoration planning from NRCS employees, NRCS partners and easement owners. (B) Investigation- Completion of technical surveys such as topographic, hydrological or habitat inventories. (C) Restoration Design- Combine data collected through coordination and technical surveys to develop functional, yet cost-effective restoration plans. (D) Implementation- Application of the easement restoration design using NRCS provided practice standards and specifications.  NRCS wetland and floodplain easements have varying levels of restoration planning completed by NRCS employees or partners. Awardees will receive all relevant planning information for easements included in this agreement. Awardee must be prepared to complete some or all the listed restoration activities.       Component 2) Wetland and Floodplain Easement Stewardship. Awardees are responsible for completing easement stewardship activities on restored wetland and floodplain easements. Easement stewardship includes repair, maintenance, management, and enhancement of properties.   (A) Repair and Enhancement- Awardee will develop repair or enhancement plans. Repair plans will be prepared when installed conservation practices fail or are damaged. Repairs may include structural and/or vegetative restoration practices, such as a dike damaged by flooding or replanting trees damaged or killed by drought. Enhancement plans are developed to improve specific aspects of a restored easement. (B) Maintenance and Management- Awardee will develop easement maintenance and management plans. These plans identify specific activities that will prolong life and improve the function of installed restoration practices. For example, maintenance plans describe how and when an earthen dike should be mowed to prevent the establishment of woody vegetation.      Component 3) Easement Assessments. The Awardee will complete onsite and offsite easement assessments. Assessments will document the habitat condition of easements and determine their compliance with deed terms and conditions. Awardees will use the data collected to determine the ecological condition of easements and, if necessary, develop repair, enhancement and/or maintenance plans to improve the condition of the assessed easements.

Expected Outcome: Projects under this topic will contribute to the following outcomes: Accelerate market expansion for European deep tech startups across EU regions and beyond by fostering collaboration and mutual support among European deep tech startup ecosystem actors; Interconnect top-tier tech startup and scaleup hubs embedded in research, technology and higher education ecosystems; Enable cross-border access to infrastructures, facilities, corporates, investors and talents to deep tech startups and scaleups, including those funded by the European Innovation Council (EIC); Enable more European deep tech startups, including women-led startups and scaleups, to succeed scaling into globally competitive companies; Strengthen less-connected innovation hubs by integrating them into a Europe-wide collaborative network; Boost private and public investment in deep tech ventures established within the participating innovation hubs. Scope: This action builds upon the EU’s strategic vision outlined in the EU Competitiveness Compass [1] , the EIC scaling strategy [2] , and the EU Startup and Scaleup Strategy [3] . It aligns with the objectives of strengthening Europe’s deep tech…

This is a notice of funding opportunity (NOFO) for the NIJ FY 2026 Crime and Justice Research. This opportunity NOFO calls for applications in two categories: Category 1: Crime and Justice Research: Category 1 will support applications for research on new programs, strategies, and technological solutions to improve workforce effectiveness, enhance operational readiness, and support safety in the adult criminal justice system. Category 2: Assessment of the Community Oriented Policing Services (COPS) De-escalation Training Program: Category 2 will support proposals to study the implementation and impact of the Community Oriented Policing Services (COPS) De-Escalation Training Program.

The National Human Genome Research Institute (NHGRI) is publishing a Notice of Funding Opportunity (NOFO) to solicit applications for the Impact of Genomic Variation on Function (IGVF) Data and Coordinating Center (DACC). The DACC will serve as the coordinating center for the IGVF Consortium and will be responsible for expanding and further developing a broadly accessible set of resources, including a data portal and a comprehensive and searchable catalog of measured and predicted variant impacts. The DACC will also seek input on the design of the catalog from the broader research community, organize and facilitate consortium activities, and seek opportunities to work with other programs and consortia. As a member of IGVF, the DACC will work with all consortium members to maximize the consortium's overall scientific impact and contribute to accelerating understanding of genomic variation.

The DOE Office of Science (SC), Office of Critical Minerals and Energy Innovation (CMEI), Office of Environmental Management (EM), Office of Nuclear Energy (NE), Office of Electricity (OE), and Hydrocarbons and Geothermal Office (HGEO) hereby announce interest in receiving applications from interdisciplinary teams addressing the Genesis Mission National Science and Technology Challenges to accelerate scientific discovery and research and development (R&D) workflows using novel artificial intelligence (AI) models and frameworks. By achieving AI advantage, these teams will advance the DOE's mission and ensure America’s security and prosperity by addressing energy, environmental, and nuclear challenges through science and technology. Teams are encouraged to leverage the extensive scientific and data resources of the DOE/National Nuclear Security Administration (NNSA), the National Laboratories, U.S. industry, and academia. The resulting AI models and workflows, if successful, may be integrated into the American Science Cloud.   DOE is soliciting new FY26 Phase I small team and Phase II large team applications in the following topic areas: advanced manufacturing, biotechnology, critical materials, nuclear fission, nuclear fusion, quantum information science, semiconductors and microelectronics, discovery science, and energy (see specific focus areas in Section III Program Descriptions).   In addition, this RFA will remain available to allow the recipients of FY26 Phase I awards to apply for larger team Phase II awards. In a few weeks, DOE plans to amend the RFA to clarify the LOI and application guidelines for FY26 Phase II awards. In FY27, DOE plans to amend the RFA or to issue an alternative funding opportunity to update the topic and focus areas to allow a second competition of Phase I small team applications and Phase II large team applications.

Expected Outcome: Proposals are expected to contribute to all the following expected outcomes: stakeholders involved in biodiversity conservation and restoration activities have an improved understanding of how direct and indirect drivers [1] of biodiversity decline work, considering spatial and temporal scales and dynamics, and their interactions; the implementation at different spatial and temporal scales of the EU biodiversity policies and legislation, notably the Nature Restoration Regulation (NRR) is improved, enabling the prioritisation of actions and the identification of systemic solutions; stakeholders, including primary producers, whose business models rely on ecosystem services are better equipped to take strategic decisions that support biodiversity, thereby increasing opportunities while reducing their exposure to risks linked to the decline of these services. Scope: Biodiversity decline has rippling effects on climate, economy, and human well-being. Focusing on representative groups of invertebrates (including insects, molluscs and crustaceans and, in particular, understudied taxonomic groups) across representative European terrestrial, freshwater and marine…

This is a notice of funding opportunity (NOFO) for the NIJ FY 2026 Research and Evaluation on Justice System Responses to Illegal Immigration. This opportunity supports proposals for rigorous, applied research and evaluations examining the adult criminal justice system (courts, law enforcement, jails, prisons, and community supervision) challenges and responses to illegal immigration and crimes committed by aliens while in the U.S. illegally at the state, local, and tribal levels. This includes, but is not limited to, location and apprehension, court operations, transportation and detention, investigating fraud and other crimes committed by illegal aliens, including creating an accurate profile of their rates of criminal activity, counter gang and criminal activity including drug and human trafficking operations. Criminal justice agencies often develop innovative solutions to local challenges that may provide insight to other jurisdictions. Applicants may propose studies examining single or multiple states and jurisdictions and models of cooperation between federal, state, local and tribal justice systems and other stakeholders. The goal of this NOFO is to identify innovative local strategies, evaluate their effectiveness, and inform practical, data-driven solutions that inform and strengthen the strategies that state, local, and tribal justice systems use to address illegal immigration.

The focus of this notice of funding opportunity (NOFO) is to produce insights into disease detection and prevention strategies, burden, severity, diagnostics, treatment, and outcomes of infectious diseases in international travelers. Timely surveillance and sentinel detection are essential for collecting actionable data. The research should:Address public health questions that improve the speed of outbreak detection.Help develop guidelines and recommendations to improve patient care.Enhance understanding of the natural history of disease.Optimize genomic surveillance as well as diagnostic and treatment strategies.Advance the global health security of the United States.This NOFO will have two components:Component A – Clinic-based sentinel network.Component B – Sentinel detection in international transportation hubs.You may apply for Component A, B, or both. If your application for both Component A and B is ranked top, Component B will be awarded.

The Department of Energy (DOE) recently announced the establishment of the Quantum Genesis initiative to develop and deploy the world’s first fault-tolerant, scientifically relevant quantum computing (SRQC) capability for research and development. The Department seeks to realize this bold ambition through the Quantum Genesis Q Competition (herein, the Q Competition), a first of its kind effort to accelerate the timeline for realizing this novel, transformative capability. The Quantum Genesis initiative will serve as a foundational pillar of the broader Genesis Mission, designed to usher in a new era of computational power for the nation and accelerate scientific discovery and innovation. The announcement of the Quantum Genesis initiative marks a significant step toward the Department’s goals outlined in President Trump’s Executive Order (EO), Ushering in the Next Frontier of Quantum Innovation and its Quantum Computer for Application Development and Discovery Science (QC-ADDS) effort.[1] This request for applications (RFA) invites proposals from domestic commercial entities have a technically viable plan for the Quantum Genesis program and achieving the milestones of the Q Competition. The intent of the Q Competition is to accelerate the development timeline for SRQCs, align successful applicants with the needs of the Department and the scientific community, and to enable the necessary scaling of quantum hardware, software, and enabling technology while developing scientific workflows that ensure SRQCs contribute to national scientific and technological advancement. In addition to the goal of building the first-generation SRQC, these partners may also help to form the technical foundation for DOE’s continued efforts into the 2030s to deploy one or more next-generation SRQCs at National Laboratories. DOE envisions this competition as a first step toward scaling fault-tolerant quantum computers to scientific relevance alongside other ongoing and planned activities. DOE acknowledges that potential vendors may have timelines that do not coincide with this competition, even though they may have a viable path to future platforms of interest to the DOE. Failure to participate or complete the milestones does not disqualify an entity or vendor from future DOE collaborations or procurements. 

Expected Outcome: Proposals are expected to contribute to all of the following expected outcomes: stakeholders are empowered to co-create, deploy and replicate viable ecosystem restoration measures leading to their wider uptake, with solutions to address implementation bottlenecks and financing issues; competent authorities in charge of implementing the EU Nature Restoration Regulation (NRR) can design and reuse effective deployment frameworks, informed by evidence and lessons generated through living labs across different contexts; social, economic and environmental co-benefits, risks and trade-offs of nature restoration activities are demonstrated, addressed and made explicit to support informed decision-making and scaling, including, where appropriate, potential One Health aspects. Scope: The NRR requires Member States to put in place area-based restoration measures, including Nature-based solutions, as highlighted and recommended in both the EU Climate adaptation strategy and in the European Water Resilience Strategy. Notably measures to implement the NRR article 9 on free-flowing rivers support the objectives of the European Water Resilience Strategy to restore and protect…

American scientists and engineers will power the super intelligence (SI) revolution in science and innovation through the Genesis Mission .  DOE SC hereby invites applications from United States (U.S.) Institutions of Higher Education and domestic doctoral-granting institutions to develop and demonstrate the effectiveness of novel four-year doctoral training pilots with dual competency in SI and another scientific discipline.  Two high-impact research experiences are required as part of the pilot, one at a DOE National Laboratory or SC user facility and one in industry.  The purpose of this pilot is to lay the foundation for the first cohort of Genesis Mission Graduate Fellows, representing a new generation of Ph.D.-level scientists and engineers with exceptional training in SI and scientific disciplines along with practical research experiences. All graduate fellowships supported by this NOFO must support research activities related to SC-relevant Genesis Mission National Science and Technology Challenges as detailed in the Request for Applications (RFA), DE-FOA-0003612 .  

Expected Outcome: Proposals are expected to contribute to all of the following expected outcomes: society, end-users, industry and decision makers better understand, anticipate and address biodiversity impacts of Europe’s reindustrialisation and decarbonisation across the value chain, from the demand-side and the design and operational phase to the end-of-life and waste phases, thus preserving biodiversity and ecosystem services by choosing least-harm transition options; society, end-users, industry and decision makers understand the benefits and impacts on biodiversity of societal, political, economic and technological choices, taking into account the direct, indirect and cumulative, and spatial and temporal dimensions, thus avoiding burden-shifting across ecosystems, regions and value chains; clean and digital industries are more resilient and provided with solutions to mitigate their impacts on terrestrial, marine and freshwater ecosystems and work towards a nature-positive economy, in line the EU Taxonomy and the Do No Significant Harm principle. Scope: One of the EU’s biggest priorities is to achieve the sovereign clean transition and digital transition. The Clean Industrial…

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes: Police Authorities in Europe are empowered with modern, accessible and validated tools, methodologies and training curricula to anticipate and cope with the misuse of new and emerging technologies for criminal purposes, with the aim to facilitate prevention, detection, efficient data access and investigation of criminal offences in a lawful manner and with full respect of fundamental rights, including the right to protection of personal data and to privacy; Reinforced interdisciplinary collaboration at the European level through the establishment of partnerships among technologists, policymakers and Police Authorities, resulting in a holistic understanding of the challenges posed by emerging technologies and in sharing of best practices; Clear guidelines and frameworks are created, including on procedures and rules, that ensure lawful access to data, balancing the needs of security with respect for privacy and that foster a European approach to the related challenges for the police and the judiciary. Scope: New and emerging technologies (e.g., new communication technologies,…

Expected Outcome: Proposals are expected to contribute to all the following expected outcomes: the mechanistic understanding of PFAS (per- and polyfluoroalkyl substances) effects on biodiversity, on ecosystems and on ecosystem services is improved and evaluations of their extent are available; research needs to close knowledge gaps and to address issues on biodiversity and ecosystem services are better identified; the new knowledge can be integrated by policymakers in their decisions related to biodiversity protection and restoration, environmental protection and protection of human health as well as in socio-economic cost-benefit analysis for policy measures on PFAS. Scope: PFAS pollution significantly impacts human health and the environment. Addressing PFAS is notably a flagship action under the Water Resilience Strategy [1] . There is growing evidence on impacts on biodiversity above and below ground and water, but more evidence is needed to substantiate the effects on different species, populations and entire ecosystems, and their extent. A European Commission study published on 29 January 2026 [2] revealed significant knowledge gaps on the effects of PFAS on biodiversity. In…

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes: Police Authorities in Europe are equipped with specialised skills and technologies to counter an increase in illegal activities related to the climate change and the emergence of new (opportunistic) criminal patterns; Improved understanding by policymakers of the effects of climate change on law enforcement with a view of developing related effective European policies; improved knowledge of the impacts of climate change phenomena on social dynamics which can raise demands from public authorities to keep public order, moving beyond traditional perspectives about crime and terrorism. Scope: Global climate change is a megatrend expected to affect our societies over the next decade. As stated in “Germany: National interdisciplinary climate risk assessment” [1] , “We are already living in the climate crisis. This brings substantial security risks at global and national levels. (...) Anyone thinking about security needs to think about climate as well”. Climate change will affect European law enforcement in various ways [2] , [3] . Notably, it is likely to create new…

The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications to characterize genomic variation to assess the impact of individual variants on genome function. This will be accomplished by systematically perturbing variants or elements using one or more high-throughput methods; collecting data on the effects of variants in DNA, RNA, or protein-coding elements on molecular, cellular, or organismal phenotypes; and developing robust, reproducible, and portable data processing pipelines. Centers funded through this initiative will become a part of the Impact of Genomic Variation on Function (IGVF) Consortium. As consortium members, centers will work together to ensure all consortium resources are accessible to a wide variety of potential users. Centers are also expected to collaborate with other consortium components to coordinate assays, variants, and cell types, and to develop shared analysis strategies to meet consortium goals.

This is a notice of funding opportunity (NOFO) for the NIJ FY 2026 Research and Evaluation on Human Trafficking. This opportunity supports proposals for rigorous research and evaluation projects to better understand, respond to, and reduce Human Trafficking in the United States in three areas: (1) prevention, including justice system and other initiatives to prevent trafficking in the first place or to prevent further harm after it has occurred, (2) evaluation of federal policies that may have the unintended consequence of perpetuating or increasing human trafficking, and (3) applied research and program evaluations that directly support effective services for American victims. This NOFO is released by the National Institute of Justice (NIJ), in collaboration with the Office for Victims of Crime (OVC).

Expected Outcome: Proposals are expected to contribute to all the following expected outcomes: more precise and more efficient biodiversity monitoring schemes, building on advanced technologies and more abundant data, are available; policymakers and relevant competent authorities have more efficient and user-friendly tools at their disposal to implement and evaluate results of the EU environmental legislation, leading to simplification of policy implementation and better protection and restoration of ecosystems. Scope: The implementation of the EU environmental legislation, in particular the Nature Restoration Regulation (NRR), the Soil Monitoring Law (SML) and the EU Water Framework Directive (WFD), requires precise monitoring of biodiversity to ensure that objectives are met. For instance, under the NRR, Member States are required to monitor annually the abundance and diversity of pollinator species using a specific monitoring method. Under the WFD implementation, the determination of ecological status of freshwater ecosystems is based on biodiversity monitoring. Under the SML, Member States have to monitor mandatorily the diversity of fungi and bacteria in soil through DNA…

Expected Outcome: Project results are expected to contribute to some or all of the following outcomes: Identification and analysis of potential new security risks related to innovative technologies being deployed in the urban and peri-urban environments; Innovative and modern tools to identify and measure changes in urban and peri-urban areas caused by the green transition, insofar as they concern security and possible resilience approaches; Verification of measures countering potential safety and security risks, hazards and challenges arising in areas hosting green technologies; Contribution to building awareness and societal acceptance for the safety and security aspects of the green transition; Impacts of incidents involving new and emerging technologies are examined, including environmental and climate risks; Security, safety and resilience aspects of the supply chains of green technologies are analysed, including the technological and resource dependencies, and their aligning with the European strategic autonomy principle; Authorities and critical infrastructure operators are equipped with efficient evaluation methodologies for safe and secure deployment and integration of…

Expected Outcome: Development of closed-loop scientific experimentation systems that integrate automation with AI-driven, trustworthy decision-making processes in existing laboratory environments; Accelerated scientific discovery with increased efficiency and reproducibility; Improved scientific productivity; Advancement of laboratory automation, including development of best practices, challenges, and opportunities for accelerating R&D; and Prototype functional demonstrators that showcase the integration of automation with AI-driven decision-making, enabling the development of closed-loop scientific experimentation systems. Scope: This topic addresses the development of safe and trustworthy closed loop scientific experimentation systems through the integration of laboratory automation with AI-driven decision-making processes and robust data infrastructures. Funded projects will help scientific labs with an already advanced level of automation and digitalisation to design, develop, and test the intelligence layer that enables scientific instrumentation to semi- or fully autonomously plan, run, and analyse experiments, ideally in coordination/network with other labs and without…

Expected Outcome: Proposals are expected to contribute to all of the following expected outcomes: Living labs working on nature restoration [1] are better connected, they are better involved in policy developments, and they benefit from existing knowledge and experience, leading to scale up of solutions for nature restoration and to address bottlenecks to implementation in particular through strengthened ownership including by local communities, private actors and public authorities; the cooperation between research, practice and policy on nature restoration is increased, with attention to practitioners involved in nature restoration (farmers, foresters, fishers and/or other businesses depending on ecosystem services) and rural/local communities and authorities as well as traditional and local knowledge holders; public authorities, land owners and/or managers, water related stakeholders, food and bioeconomy actors and practitioners have access to shared, validated deployment and governance frameworks that support the scale up of nature restoration actions as well as estimates for demand for certified environmental outcomes supporting restoration objectives (certified carbon…

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes: Increased understanding of European policy makers, research community, biotech companies, and relevant security practitioners of the threat of bioterrorism and of synthetic biology, including a thorough lawful analysis of what needs to be monitored in this context, what needs to be regulated and how; Awareness raised within the related scientific community how research in synthetic biology can be used for malicious purposes. Scope: The rising threat of bioterrorism is driven by recent scientific advancements, notably by growing accessibility of synthetic biology, genetic engineering, related commercial services and public databases, which in turn enhance their obtainability to non-state actors and individuals with malicious intentions. The proliferation of do-it-yourself biohacking and community laboratories, including gene editing and sequencing technology, dropping costs of equipment and increased simplicity of use may inadvertently facilitate knowledge and skills dissemination about biological threats and open new pathways for bioterrorism. Challenges in detection,…

The U.S. Army Corps of Engineers (USACE) Engineer Research and Development Center (ERDC) is issuing this announcement for various research and development topic areas. The ERDC consists of the Coastal and Hydraulics Laboratory (CHL), the Geotechnical and Structures Laboratory (GSL), the Environmental Laboratory (EL) and the Information Technology Laboratory (ITL) in Vicksburg, Mississippi, the Cold Regions Research and Engineering Laboratory (CRREL) in Hanover, New Hampshire, the Construction Engineering Research Laboratory (CERL) in Champaign, Illinois, and the Geospatial Research Laboratory (GRL) in Alexandria, Virginia. The ERDC is responsible for conducting research in the broad fields of hydraulics, dredging, coastal engineering, instrumentation, oceanography, remote sensing, geotechnical engineering, earthquake engineering, soil effects, vehicle mobility, self-contained munitions, military engineering, geophysics, pavements, protective structures, aquatic plants, water quality, dredged material, treatment of hazardous waste, wetlands, physical/mechanical/ chemical properties of snow and other frozen precipitation, infrastructure and environmental issues for installations, computer science, telecommunications management, energy, facilities maintenance, materials and structures, engineering processes, environmental processes, land and heritage conservation, and ecological processes. This announcement is continuously open; pre-proposals may be submitted and will be reviewed at any time throughout the year. The availability of funds may limit the ability of the U.S. Government to make awards in specific areas, nevertheless pre-proposals are sought under this announcement for all research areas identified. For additional details on the research topic areas and how to submit pre-proposals, please go to: https://www.erdcwerx.org/u-s-army-engineer-research-and-development-center-broad-agency-announcement/

This is a notice of funding opportunity (NOFO) for the BJA FY 2026 DNA Capacity Enhancement for Backlog Reduction (CEBR)—Formula Grants Program. This opportunity will support states and units of local government with existing crime laboratories that conduct DNA analysis to process, and/or to increase the capacity to process, more DNA samples for entry into the Combined DNA Index System (CODIS), thereby helping to reduce the number of forensic DNA and DNA database samples awaiting analysis and/or to prevent a backlog of forensic and database DNA samples.

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes: Improved understanding of links between addictions and crime, including drivers of criminality; Innovative and effective solutions, including training curricula, for Police Authorities in Europe and relevant Civil Society Organisations (or Non-Governmental Organisations) to prevent addictions and related crimes, with a special attention to young people at risk; Evidence-based support to modernising European criminal justice system’s approach when dealing with addiction-related offenses; Novel approaches of collaboration between different stakeholders, primarily Police Authorities in Europe and Civil Society Organisations (or Non-Governmental Organisations), to increase communities’ addiction resilience, security and safety. Scope: A close and complex relationship exists between addictions, such as gambling, drug or alcohol use, and crime (e.g., criminals are often under the influence of drugs while committing crimes, gamblers or drug users commit crimes to pay for their debts or drugs). In this topic, successful proposals are expected to analyse the specific nexus…

The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications to study the effects of genetic or environmental interactions on genomic variant impact. To accomplish this, interaction centers will first propose a research framework to investigate whether interactions with effects beyond additive are important modifiers of the impact of variants. Centers will apply their framework to experimentally test combinations for interactions and share their data as well as analyses through the Impact of Genomic Variation on Function (IGVF) portal and catalog. Centers will share their method for predicting the most important combinations for future testing. The rationale for this combination of research and resource work is the identification of a structure within the interaction landscape might result in better predictions of the most important interactions to test, leading to more effective variant testing, better understanding of genome-wide association studies (GWAS), and improved polygenic scores. As IGVF Consortium members, centers will work together to ensure all consortium resources are accessible to a wide variety of potential users. Centers are also expected to collaborate with other consortium components to coordinate assays, variants, and cell types, and to develop shared analysis strategies to meet consortium goals.

Expected Outcome: Proposals are expected to contribute to all of the following expected outcomes: policy and decision makers at relevant levels are better equipped to incorporate educational, cultural, societal and behavioural insights related to biodiversity – such as business dependencies, vulnerabilities and systemic risks – into future policy development, including through participatory and co-designed approaches; institutional, business, financial and economic actors have better awareness on the systemic effects of their interactions and interdependencies with ecosystems, including international trade, across value chains; the understanding and mapping of cross-actor and cross-sectoral relationships and their associated knowledge production and decision-making pathways are improved; transdisciplinary research communities from natural and social sciences and humanities (SSH), as well as cultural and creative sectors, among others, collaborate to improve understanding on the indirect drivers [1] behind biodiversity-harming practices, identify leverage points and test evidence-based interventions – including in relation to governance, incentives, narratives, norms and power…

The U.S. Department of Agriculture (USDA), Agricultural Marketing Service (AMS), requests applications for the fiscal year (FY) 2026 Specialty Crop Multi-State Grant Program (SCMP). The SCMP supports collaborative multi-state partnerships to enhance the competitiveness of specialty crops through competitively funded projects. A multi-state partnership is a project that implements activities with measurable outcomes that benefit two or more U.S. States and/or Territories along with non-profit entities. The focus is to address regional or national level specialty crop issues, including, but not limited to, food safety, plant pests and disease, research, crop-specific projects addressing common issues, and marketing and promotion. Projects must enhance the competitiveness of U.S. or U.S. territory-grown specialty crops in either domestic or foreign markets.

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes: Accelerated adoption of high-TRL (Technology Readiness Level) disaster risk solutions across diverse sectors; Facilitated integration of innovative technologies into existing disaster prevention, preparedness, response, and recovery frameworks; Promoted collaboration among stakeholders to scale proven solutions and enhance resilience; Addressed barriers to deployment, ensuring accessibility and usability of advanced DRS technologies; Strengthened evidence-based decision-making through demonstration and validation of high-TRL solutions in real-world scenarios; Promoted visibility of civil security research results. Scope: This topic aims to foster the widespread adoption and integration of high-TRL (Technology Readiness Level) disaster risk solutions (DRS) across multiple sectors, enhancing societal resilience to various hazards, including climate. The focus is on overcoming barriers to deployment, ensuring accessibility, and strengthening collaboration among stakeholders to drive innovation uptake. Projects should promote the adoption of high-TRL solutions by public and…

This is a notice of funding opportunity (NOFO) for the BJA FY 2026 National Center for Veterans Justice. This opportunity will establish a national center to provide specialized support to state, local, and tribal criminal justice agencies; treatment and service providers; courts; corrections systems; and community supervision agencies to effectively support and respond to the needs of veterans across the justice system, improve outcomes, and strengthen public safety. The Center will serve as a one stop shop to address critical gaps in veteran identification, cross-system coordination, and implementation of evidence-based interventions by providing criminal justice professionals with specialized tools, training, and technical assistance on military culture, combat trauma, military sexual trauma (MST), post-traumatic stress disorder (PTSD), traumatic brain injury (TBI), and other veteran-specific considerations. Providing resources and specialized technical assistance through a centralized location and entity is essential to effectively supporting veterans whose needs require coordination across multiple systems, including criminal justice, Department of Veterans Affairs (VA), behavioral health, and social service systems that operate under distinct legal frameworks and institutional priorities.

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes: Development of innovative tools and methodologies to monitor and improve risk awareness across society, integrating diverse community perspectives and leveraging advanced technologies; Development and uptake solutions and tools for the successful increase of safety culture and societal resilience of communities with concrete material, while considering also the inclusion and protection of marginalized populations in disaster scenarios; Creation of comprehensive, inclusive preparedness plans that involve all societal sectors and governance levels, ensuring coordinated and effective responses to disasters (such as from early warning to early action), including scarcity of resources; Establishment of a resilient, adaptive response framework that enhances collaboration between public authorities, communities, and private sectors, improving overall disaster resilience. Scope: Building on the whole-of-society and whole-of-government approach, this topic should contribute to enhancing risk awareness and disaster preparedness through the development of innovative tools,…

Expected Outcome: Support the adoption of market-ready innovative AI-powered cybersecurity solutions, including solutions developed in the framework of EU-supported research and innovation projects. Provide and deploy up to date AI-powered tools and services to organisations (in particular SMEs) to prepare, protect and respond to cybersecurity threats. Integrate AI technologies into cybersecurity processes to improve the security of ICT solutions, including providing innovative approaches to training employees to use AI solutions for cybersecurity. Deployment of cybersecure tools and technologies relying on trustworthy AI; AI driven cybersecurity tools; Integration of tools to protect and secure AI solutions. Objective: To support the market uptake and dissemination of innovative AI-powered cybersecurity solutions (notably in SMEs, possibly using results stemming from Horizon Europe projects or similar) and improve knowledge and auditing of cybersecurity preparedness. SMEs often lack the resources to assess cyber risks, develop cybersecurity strategies and implement solutions, leaving them vulnerable to cyberattacks. The resilience of organisations that fall into this category is…

This is a notice of funding opportunity (NOFO) for the OJJDP FY 2026 Multistate Mentoring Programs. This opportunity supports the implementation and delivery of mentoring services to youth populations that are at risk or high risk for delinquency, victimization, and going into the juvenile justice system. Mentoring services can be one-on-one, group, peer, or a combination of these types.

Expected Outcome: Proposals are expected to contribute to all the following expected outcomes, in full alignment with the OceanEye initiative: scientists, public authorities and businesses benefit from strengthened and resilient global ocean observing capacities, coordinated under the Intergovernmental Oceanographic Commission’s Global Ocean Observing System (GOOS), [1] through the deployment of ocean observation equipment, in particular for the provision of critical observations for marine biodiversity and ecosystem knowledge; public authorities prioritise investments on infrastructures and capacity building to advance ocean research, protect and restore ocean health and biodiversity and provide critical services through a global ocean observing system and data delivery that is fit-for purpose, cost efficient and designed across all its components; increased EU leadership and strategic autonomy in global ocean observation capabilities, in support of EU climate and biodiversity goals, strengthening the EU’s contribution to and influence within GOOS, and reducing the risk of critical dependencies, notably for key services (i.e. Copernicus Services); enhanced collaboration between…

Expected Outcome: Industrial jobs are transformed through AI-based human-machine interactions (and skills linked to them) which enhance flexibility, inclusion, well-being, up-skilling, career evolution and knowledge sharing; Increased competitiveness and sustainability of advanced manufacturing industries by means of knowledge formalization and adaptability of the machines to workers and markets based on different cultures. Scope: Innovative AI approaches are poised to revolutionise human-machine collaboration in factories by fostering an environment where technology and human expertise synergistically enhance each other. AI can enhance the value of the companies by capturing and formalising the knowledge which is dispersed and not explicit. This allows companies to really own the knowledge and use it to reduce the onboarding time of new employees and support personnel upskilling to adapt to the evolving technological landscape. AI has a great potential to make task simpler by reducing the complexity offering intuitive interfaces and real-time feedback allowing workforce to be more efficient and effective while facilitating access to more complex tasks including those involving…

This is a notice of funding opportunity (NOFO) for the Comprehensive Opioid Stimulant and Substance Use Program (COSSUP) Training and Technical Assistance (TTA). This opportunity will provide training and technical assistance to BJA COSSUP grantees to address technical operational challenges to improve responses to overdose deaths, illicit opioids, stimulants, and other substances.

Expected Outcome: Projects are to contribute to all of the following outcomes: European Union’s, Member States’ and Associated Countries’ policy making is supported with robust evidence and their visibility in deliberations of SRM strengthened. Evidence and new knowledge related to the points below supports the European Union’s, Member States and Associated Countries’ contributions to relevant international review and assessment processes of SRM, notably by the IPCC: Civil society, researchers, public authorities as well as policy and decision makers have access to a solid scientific-technological knowledge foundation concerning the detection, attribution and deterrence of SRM activities as a contribution to an emerging multilateral governance system spanning both SRM-related research and technological development. The development of a global SRM governance framework is supported through advanced knowledge, generated by desk research, modelling, earth observation, the documentation of development pathways of various SRM technologies and their potential impacts on the earth system and its parts (oceans, large-scale atmospheric circulation, regional climate such as monsoons as well…

Expected Outcome: Innovative advanced materials designed for circularity are adopted in products faster, through accelerated production and technology uptake; Business models become available to enhance the use of circular advanced materials in strategic value chains; and Resource efficiency (materials and energy) is increased significantly through a focus on circular advanced materials. Quality standards, harmonisation and regulatory requirements are addressed facilitating simplified market transition. Scope: The focus of this topic is on enabling circularity and resilient supply networks through R&I in advanced materials, in particular recyclable polymers and composites, magnets and metal (alloys) for additive manufacturing, and on accelerating their pathway to market. Proposals should develop new innovative advanced materials (IAMs) with superior or novel functionalities designed for circularity. The scope includes necessary developments of related processes and technologies to ensure integration in industrial manufacturing facilitating uptake of the developed solutions. Proposals should also develop circular business models considering the cost of changes needed along the life…

The U.S. Department of Agriculture, Animal and Plant Health Inspection Service announce this funding opportunity to carry out the Plant Protection Act Section 7721 (PPA 7721) National Clean Plant Network (NCPN) program. APHIS will consider project proposals that clearly and directly support the strategic goals and objectives of the National Clean Plant Network as described in the NCPN Strategic Plan . The purpose of the NCPN program is to establish a network of Clean Plant Centers for diagnostic and pathogen elimination services to produce clean propagative plant material and to maintain blocks of pathogen-tested plant material in sites located throughout the United States. The NCPN provides propagative plant material free of targeted plant pathogens to protect the environment and ensure the global competitiveness of U.S. specialty crop producers. Program priorities align with the goals specified in the NCPN Strategic Plan and include: 1) Optimizing the production, maintenance, and distribution of clean plants, 2) Advancing special initiatives by optimizing the adaptation and implementation of novel technologies and new ideas while increasing the awareness of the importance, availability, and use of clean plants, and 3) Optimizing network resources. Applicants should refer to the NCPN Request for Proposals on the USDA APHIS NCPN website for additional details. APHIS is providing at least $10 million in funding for the Plant Protection Act (PPA) National Clean Plant Network (NCPN) program under Section 420 of the PPA (7 USC § 7721). The purpose of the NCPN program is to establish a network of Clean Plant Centers for diagnostic and pathogen elimination services to produce clean propagative plant material and to maintain blocks of pathogen-tested plant material in sites located throughout the United States. Additional details about the program are available on the USDA APHIS NCPN website. Program Goals: The National Clean Plant Network (NCPN) was established under The Food, Conservation and Energy Act of 2008 (Farm Bill) Title X, Sec 10202. Its purpose is to support a network of clean plant centers in the United States for specialty crops to provide reliable sources of propagative material that are free of targeted propagative-borne pathogens. Network clean plant centers conduct diagnostic and pathogen elimination services and establish foundation blocks (nuclear stock) to provide pathogen-tested plant materials to nurseries, growers, and to state certification programs.  Expected Outcomes: Projects funded under this announcement are expected to support programs that provide propagative plant material free of targeted plant pathogens to protect the environment and ensure the global competitiveness of U.S. specialty crop producers. Funding Priorities: APHIS will consider project proposals that clearly and directly support the strategic goals and objectives of the National Clean Plant Network. Program priorities align with the goals specified in the NCPN Strategic Plan and include: 1) Optimizing the production, maintenance, and distribution of clean plants, 2) Advancing special initiatives by optimizing the adaptation and implementation of novel technologies and new ideas while increasing the awareness of the importance, availability, and use of clean plants, and 3) Optimizing network resources. Projects that support one of the current crop groups in NCPN and show coordination with the appropriate NCPN specialty crop governing body are prioritized for funding. Existing Federal or State facilities with demonstrated capacity to provide clean plant material are also prioritized for funding. Applicants can find all application materials on the ezFedGrants website or the Grants.gov website by searching Assistance Listing number 10.031 . Application materials and additional i nformation are also available on the USDA APHIS NCPN website . All application materials are compliant with Section 508 of the Rehabilitation Act of 1973 for accessibility.

Expected Outcome: A viable industrial ecosystem for circularity in manufacturing industries emerges, enhancing both circularity and resilience; De-manufacturing technologies and practices become available, making decisive contributions to a European remanufacturing industry and market; Functions of products are retained, reused, upgraded or adapted through de-manufacturing and re-manufacturing; and Skills, standards and safety measures relevant to remanufacturing are developed. Scope: Proposals should focus on developing de-manufacturing and re-manufacturing technologies at the factory level, addressing at least three of the following: Technologies to efficiently analyse part condition and support predictive maintenance, including for re-manufactured parts or components of lower value, e.g. by combining multimodal sensor data, AI and human inputs; AI and robotic-assisted technologies, e.g. innovative end-effectors, to de-manufacture products and components, including handling, sorting and extended logistics; Model-based systems, to allow de-manufacturing and re-manufacturing operators to use CAD data and digital twins related to the original parts (and contribute to the…

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes: Housing-led approaches [1] aligned with the NEB are made available to stakeholders involved in tackling homelessness [1] . Robust evidence on NEB-aligned housing-led approaches tackling homelessness (including people temporarily hosted by acquaintances and family) to inform the development and/or update of policies and services for prevention and early intervention in the context of the green transition [1] in neighbourhoods [1] . Scope: Social and affordable housing is being advanced in the EU, including through the Affordable Housing Initiative [5] . Despite efforts, current policies for the green transition are failing to adequately address the housing crisis. Homelessness remains a structural challenge across Europe, with negative impacts on both individuals experiencing it (e.g. physical and mental health, social and economic conditions) and neighbourhood communities [1] (e.g. pressure on public services, erosion of social fabric [1] , etc.). Research and innovation gaps in tackling homelessness range from data collection (i.e. the variety of approaches to defining,…

This is a notice of funding opportunity (NOFO) for the NIJ FY 2026 Research on Gender Dysphoria and Violent Crime. This opportunity will support foundational research on gender dysphoria, its treatment, and the perpetration of violence and violent behavior. Available empirical evidence regarding this topic is limited, particularly in regard to underlying causal mechanisms. To address these gaps, NIJ is interested in retrospective, secondary data analyses that explore gender dysphoria, its treatment, and the perpetration of violence and violent behavior. Examples include, but are not limited to: • Prevalence rates of violent crime and behavior for this population, to include demographic information and crime type characteristics. • Post-conviction analyses, to include analyses based on individuals who have been incarcerated. • Analyses examining the relationship between violence and gender dysphoria diagnosis and/or treatment. • Research on the victim/offender overlap or other contextual factors to interpret trends. • Impact of comorbidities (e.g., substance use disorders and/or mental health disorders) on the relationship between violence and gender dysphoria diagnosis and/or treatment.

The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. The purpose of this Notice of Funding Opportunity is to establish the GREGoRi Technology Integration Center, which will enable the development of standards and best practices for applying new and emerging molecular methods in rare disease diagnosis. A major deliverable of the Center will be a multidimensional dataset that can be used for the development and benchmarking of novel tools and strategies that facilitate rare disease diagnosis.

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes: An increased number of local authorities systematically identify and quantify vacant, obsolete or underutilised spaces for reuse in neighbourhoods [1] in a context-sensitive way to address local community [1] challenges and needs. Increase in renovated, renatured, or converted spaces that address local community challenges and needs. Scope: Europe’s housing needs, inefficient use of the existing building stock, environmental commitments, and the EU’s goal of “no net land take” by 2050 make a compelling case for reusing the significant number of existing spaces, including buildings and infrastructure, that are vacant, obsolete or underutilised. In Europe, there are, for instance, an estimated 19,000 km² of underutilised brownfield land and 300 km² of vacant or underutilised office space [3] . The reuse of vacant, obsolete or underutilised spaces, following circularity [1] and sufficiency principles, can help address community challenges and needs thanks to their typical proximity and connection to essential infrastructure and services. While vacant, obsolete or underutilised…

This is a notice of funding opportunity (NOFO) for the FY26 Students, Teachers, and Officers Prevention (STOP) School Violence Program. This opportunity supports programs to prevent and reduce school violence by implementing training, developing school threat assessment teams and/or intervention teams to identify violence risks, introducing technologies like anonymous reporting tools, or applying other school safety strategies that assist in preventing violence. The Student, Teachers, and Officers Preventing School Violence Act of 2018 (STOP School Violence Act) describes the following allowable uses of funding for school safety projects: • Training to prevent student violence against others and self, including training for local law enforcement officers, school personnel, and students. • The development and operation of technology solutions such as anonymous reporting systems for threats of school violence, including mobile telephone applications, hotlines, and internet websites. • The development and deployment of: o School threat assessment and intervention teams that include coordination with law enforcement agencies and school personnel or o Specialized training for school officials in responding to mental health crises. BJA’s STOP School Violence Program improves school safety and security by providing students and teachers with the tools they need to recognize, respond quickly to, and help prevent acts of violence. Activities that go beyond the allowable uses of funding as described above will not be funded.

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated, early phase, clinical trials of natural products (i.e., botanicals, dietary supplements, and probiotics), which have a strong scientific premise to justify further clinical testing. For this NOFO, natural products include promising nutritional regimens that standardize the amount of a specific naturally occurring nutritional compound (e.g., omega-3 fatty acids, anthocyanidins, or polyphenols) and have compelling preliminary evidence. Under this NOFO, trials must be designed so that results, whether positive or negative, will provide information of high scientific utility and will support decisions about further development or testing of the natural product. This NOFO will provide up to 3 years support for studies to replicate the impact of the natural product on target engagement when used by humans, and assess whether there is an association between the degree of the impact on target engagement and functional or clinical outcomes in a patient population. Applications are encouraged to design studies to determine how to optimize the impact of the natural product on target engagement by optimizing the delivery of the natural product through examination of different doses or formulations. In addition, applications can be designed to combine the natural product with another treatment approach that is known to engage the same target; or study the impact of the natural product in a target population that is more responsive. Clinical trials submitted under this NOFO are expected to be hypothesis based, milestone-driven, and directly related to the research priorities and mission of NCCIH. This R33 funding mechanism is intended to accelerate the translation of emerging basic science findings about natural products into early-stage clinical testing to determine whether continued clinical research is warranted. This NOFO will not support efficacy or effectiveness trials, nor will

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes: Robust evidence on how inhabitants experience their neighbourhood [1] and the impact of these experiences on their health and well-being. The research informs policies, strategies, neighbourhood planning and procurement for the green transition [1] of neighbourhoods, including their nature-positive [3] transformation and climate resilience. Scope: Neighbourhoods are human-social constructs and environments. They are shaped by complex inter-connections and interdependencies of human and non-human actors in the natural and built environment [1] they comprise. An increasing body of research is looking at the relationship between people and the built environment, from neuro-architectural aspects of space to atmosphere and ambiance aspects in urban design and planning, influencing also the perception of beauty. Digitalisation is also allowing to understand, map and enhance how inhabitants experience the built environment. Yet, more evidence is needed on how inhabitants react to and identify with their neighbourhoods as well as the effects of these experiences on their physical and…

The National Parks Business Plan Internship (BPI) goal is to jointly administer a graduate-level internship program focused on improving the business management and operational health of our national parks and NPS programs.  The internship program should: Provide students with in-depth training on NPS business management and operations, exposure to park and/or program level operations, and the opportunity to conduct substantive analysis and evaluation which lead to recommendations that improve strategic planning and management decision-making.  Encourage highly qualified graduate students from professional disciplines underrepresented in the NPS workforce (Master of Business Administration, Master of Public Policy, Master of Environmental Management, and similar degree programs) to explore federal careers with conservation and land management agencies. Cultivate a lifelong stewardship ethic for public lands in graduate students from top universities. Eligible recipients are State, local and tribal governments, other public entities, educational institutions, and private nonprofit organizations. 

Expected Outcome: Depending on the decision of each NCC, one or more of the following should be covered: Network of national initiatives to accelerate the cybersecurity industry and facilitate Access-to-Market. European frameworks for establishing cybersecurity incubators and accelerators. Cybersecurity Community Observatory to inform subsequent policy interventions by the ECCC and NCCs. Matchmaking events to create connections and build trust; platforms and events for Access-to-Finance and Access-to-Market including in the area of dual-use technologies. Strengthened Cybersecurity Community to support the European Cybersecurity Industrial, Technology and Research Competence Centre; Maintained technical registration possibilities for candidates for the Cybersecurity Competence Community; Technical assistance for potential applicants for ECCC calls. Uptake of cybersecurity solutions. Strengthened cybersecurity capacities of stakeholders. Synergetic activities that strengthen the role of NCC. Centralised the many initiatives focusing on raising awareness and work together with other NCCs to support a cross European approach covering education, studies, training courses and awareness…

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes: Demonstrated approaches aligned with NEB allow architects, designers, spatial planners and neighbourhood [1] decision makers to ensure an efficient and effective integration of user perspectives in the spatial design and/or transformation of public spaces. The demonstrated approaches deliver positive climate, environmental, social and cultural impact (such as addressing inequalities and enhancing social cohesion, community [1] resilience, civic engagement and a sense of security, ownership and belonging). Scope: The design of neighbourhood public spaces defines their functionality, but also other aspects such as power dynamics and sense of belonging. A fair green transition [1] calls for neighbourhood public spaces to be designed and managed for diverse users. Integrating new methods (such as research-by-design, security-by-design [4] , or life-centric design) in the architectural design and spatial planning of public space can help reflect on the values, practices and stakeholder relations that underpin the design of public spaces; rethink how public spaces are understood;…

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes: Improved preparedness, evidence-based approaches and response capabilities, along with a strengthened ability to mitigate risks from diverse threats, by integrating validated disruptive technologies into real-world operations; Accelerated adoption of innovative solutions by reducing barriers through rigorous testing and validation, fostering collaboration among public authorities, industry, and researchers to align technologies with real-world needs. Scope: This topic aims to support the integration of disruptive technological innovations [1] into civil security by strengthening research and innovation activities that enhance preparedness, response capabilities, and risk mitigation. A key focus is bridging the gap between early-stage, low Technology Readiness Level (TRL) research and applied security solutions, ensuring that emerging technologies are effectively transitioned into operational use. Proposals should prioritize disruptive solutions that address diverse security threats while improving the efficiency and effectiveness of civil security operations. Emphasis…

The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications to develop, apply, and test predictive models and perform integrative analyses to determine the impact of genomic variation on genome function. Centers funded through this initiative will become a part of the Impact of Genomic Variation on Function (IGVF) Consortium. As consortium members, centers will work together to ensure all consortium resources are accessible to a wide variety of potential users. Centers also will collaborate with other consortium components to guide and optimize IGVF experimental design, to provide analytical expertise and support for consortium-wide efforts, and to develop and execute shared analysis strategies to meet consortium goals.

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes: Integrated single-hazard systems into multi-hazard next generation predictive models to assess cascading effects (e.g., heatwave, floods, droughts, landslides, heavy rain) and interactions across meteorological, geophysical, and technological hazards; Enhanced hazard forecasting and response through research on model integration and platform interoperability; Development of holistic risk and resilience metrics to support multi-hazard prevention strategies, encompassing main physical, economic and social effects; Improvement of analysis models considering evolving vulnerability state, due to cascading and cumulative effects, through numerical simulations and experimental tests, possibly also supported by AI applications; Collected reliable data (same granularity and format) and ways to share and analyse it. The interoperability of all kinds of systems and information sharing is crucial, based on the need-to-know principle; Improved knowledge/experience-sharing from past emergencies to cope with future emergencies, also strengthening trans-national knowledge and data…

This is a notice of funding opportunity (NOFO) for the OJJDP FY 2026 Internet Crimes Against Children (ICAC) Task Force Program Support. This opportunity supports a national network of 61 multiagency, multijurisdictional task forces engaged in investigations, forensic examinations, and prosecutions related to technology-facilitated child sexual exploitation. This is accomplished through the provision of services and support to OJJDP, the ICAC task forces, ICAC National Training providers, and other federal, state, and local law enforcement agencies partnering with the ICAC Task Force program. Funds will support activities that enhance training access, expand prevention and outreach capabilities, advance the National Strategy for Child Exploitation Prevention and Interdiction, and improve collaboration among ICAC task forces.

Expected Outcome: Project results are expected to contribute to the following expected outcomes: Development of closed-loop scientific experimentation systems that integrate automation with AI-driven, trustworthy decision-making processes in existing laboratory environments; Accelerated scientific discovery with increased efficiency and reproducibility; Improved scientific productivity; Advancement of laboratory automation, including development of best practices, challenges, and opportunities for accelerating R&D; Prototype functional demonstrators that showcase the integration of automation with AI-driven decision-making, enabling the development of closed-loop scientific experimentation systems. Scope: This topic addresses the development of safe and trustworthy closed loop scientific experimentation systems through the integration of laboratory automation with AI-driven decision-making processes and robust data infrastructures. The funded project will help scientific labs with an already advanced level of automation and digitalisation to design, develop, and test the intelligence layer that enables scientific instrumentation to semi- or fully autonomously plan, run, and…

This is a notice of funding opportunity (NOFO) for the OJJDP FY 2026 Missing and Exploited Children Training and Technical Assistance program. This opportunity will build the capacity of state, Tribal, and local agencies to effectively investigate and prosecute cases of missing and exploited children. The program provides assistance to multidisciplinary teams of prosecutors, state and local law enforcement, child protection personnel, medical providers, and other child-serving professionals to strengthen multidisciplinary responses to cases of missing and exploited children and improve the investigation and prosecution of perpetrators.

This is a special Notice of Funding Opportunity Announcement (NOFO) sponsored by the Air Force Office of Scientific Research (AFOSR), which will hereafter generally be referred to as “we”, “us”, “our”, or “AFOSR.” The Fiscal Year 2027 Air Force Young Investigator Research Program (YIP) intends to support individual early career scientists and engineers who have received their Ph.D. or equivalent degrees by 01 April 2019 or later showing exceptional ability and promise for conducting basic research. The program objective is to foster creative basic research in science and engineering; enhance early career development of outstanding young investigators; and increase opportunities for the young investigators to recognize the Air Force and Space Force mission and related challenges in science and engineering. Individual awards are made to U.S. institutions of higher education, industrial laboratories, for- profit, or non-profit research organizations where the principal investigator (PI) is employed on a full-time basis and holds a regular, non-contractor position. A YIP PI must be a U.S. citizen, national, or permanent resident. Researchers working at a Federally Funded Research and Development Center (FFRDC), or a Department of War (DoW) Laboratory are not eligible for this competition. YIP awards are funded up to $150,000 per year for three years, for a total of $450,000. No single year may exceed $150,000. Please review the remainder of this announcement for additional information. Under this competition, an anticipated thirty-seven (37) traditionally funded YIPs and three (3) YIPs funded in partnership with the Laboratory for Physical Sciences (LPS) in the Quantum Information Sciences research discipline may be awarded. There may be potential for an additional 37 YIPs funded from other AFOSR research funding. All actions are based on the availability of funds. Proposers are encouraged to confer with the designated AFOSR Program Officer(s) prior to submitting a full proposal. We will evaluate proposals using an internal review panel. AFOSR reserves the right to select and fund all, some, or none of the proposals from any of the topics below. AFOSR provides no funding for direct reimbursement of proposal development costs. Technical and budget proposals (or any other material) submitted in response to this NOFO will not be returned. It is the policy of AFOSR to treat all white papers and proposals submitted under this NOFO as sensitive competitive information and to disclose their contents only for the purposes of evaluation. White papers briefly summarizing the proposed institution’s ideas are required . Submit white papers to our whitepaper portal, which is linked below. The topic points of contact (POCs) will coordinate to provide feedback on the white papers. The proposals will need to include a data management plan, outlining how samples and data collected in the program will be stored and managed. This includes but is not restricted to issues such as standards for data and metadata collection, content and format, data archiving, database management, and data sharing within, outside the awardee and beyond the lifetime of the grant. This precondition is modeled on the National Science Foundation Data Management Plan requirement (e.g., https://www.nsf.gov/eng/data-management-plans). IMPORTANT NOTE: Applicants should be alert for any amendments that may modify the announcement. Amendments to the original Notice of Funding Opportunity (NOFO) will be posted to the Grants.gov Webpage: https://www.grants.gov/. IMPORTANT DATES: Pre-proposal inquiries and questions, regarding white papers and the submission of those white papers, must be received in writing by electronic mail to the address(es) of this NOFO not later than 17 September 2026 at 11:59 PM Eastern Time to be considered. The Government will respond to any pre-proposal inquiries or questions via public posting, or individual responses, no later than COB on 24 September 2026. Whitepapers must be received by 09 October 2026 at 11:59 PM Eastern Time via submission to https://afosr.gov1.qualtrics.com/jfe/form/SV_eKuTqm9qezoDYep to be considered. White paper evaluation is meant to initially assess the capability of a proposed effort. White papers must be no more than five (5) pages in length. References and CV/bios will not count against the page limit. Please review this announcement in its entirety prior to submitting a white paper. The government will respond to the white paper determination before COB on 06 November 2026 . Proposals must be received electronically through Grants.gov by 04 December 2026 at 11:59 PM Eastern Time to be considered. We anticipate that we will notify proposers of selection or non-selection for award no later than 26 April 2027 . We anticipate awards to be made by 01 May 2027 , barring delays. 

The NOFO supports CDC"s efforts to protect U.S. residents traveling internationally. The goal is to help U.S. travelers with pre-travel preparation, access to timely health information while traveling, and timely research on health conditions.The project will:Improve access to high quality travel preparation information for both healthcare providers and travelers.Collect health information before, during, and after travel through innovative electronic medical record (EMR), web, and mobile phone applications.Build on this platform to conduct timely research on emerging health threats.This NOFO will also increase the awareness of travel medicine among primary care providers and provide them with appropriate tools in advising international travelers with up-to-date recommendations.

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes: Project promoters, public authorities, and investors have a better understanding of the capital market demand and supply dynamics that underlie investments in projects fostering the transformation of neighbourhoods [1] in line with the New European Bauhaus (NEB). Increased investments towards NEB-aligned projects for the sustainable [1] and inclusive [1] transformation of neighbourhoods. Scope: Increased investment in projects for the transformation of neighbourhoods in line with the New European Bauhaus (NEB) may be hindered due to a discrepancy between the demand and supply of capital in terms of size, diversity, returns, and risk. Small-scale NEB-aligned projects typically encounter large, short-term oriented, and highly risk-averse investment funds, which seek investment opportunities able to absorb large amounts of funding, driven by present legislation [4] . Place-based impact investing is an approach that can contribute to investments in NEB-aligned neighbourhood projects by providing risk-adjusted financial returns while creating local social, cultural, aesthetic [5] and…

The National Institute for Occupational Safety and Health (NIOSH) supports research projects that address: (1) physical and mental health conditions related to the September 11, 2001, terrorist attacks; (2) diagnosing conditions for which there has been diagnostic uncertainty; and (3) treating conditions for which there has been treatment uncertainty. Conditions may have emerged since the treatment program began or since the WTC Health Program was established. This announcement solicits meritorious and scientifically rigorous applications that will: 1) improve diagnosis and treatment activities of the WTC Health Program; 2) expand knowledge about health effects related to the September 11, 2001, terrorist attacks; 3) answer critical questions about WTC-related physical and mental health conditions; and 4) apply lessons learned to improve response to future disasters. Potential projects may include, but are not limited to: (a) Screening research to evaluate current methods or facilitate the development of new or improved methods to detect disorders or health conditions; (b) Diagnostic research to evaluate current methods or facilitate the development of new or improved methods to identify diseases, disorders, or conditions; (c) Treatment research to evaluate or identify improved treatment interventions or methods, or to promote development of new or novel approaches; (d) Prevention research to identify or evaluate methods and interventions that prevent or mitigate the development or recurrence of diseases or disorders; (e) Quality of life research to identify, develop, or evaluate methods or interventions that improve comfort and quality of life for individuals with chronic illness or multimorbidity; (f) Omics research to improve methods for predicting disorders by identifying and understanding relationships between genes and illness (e.g., phenotypes and biomarkers), including how genetic factors influence disease development or response to treatment; (g) Epidemiologic or clinical research to identify patterns, causes, and control of adverse health effects among the 9/11-exposed population; (h) Health services research to examine access to care, cost of care, and outcomes associated with care delivery; (i) Implementation research to evaluate how research findings are disseminated, adopted, implemented, sustained, and scaled in real-world settings; and (j) Epidemiologic research to investigate emerging conditions where preliminary data suggest, but do not confirm, a causal relationship between 9/11 exposure and the condition. Examples can be found at https://www.cdc.gov/wtc/received.html.

The National Endowment for the Humanities (NEH) Division of Lifelong Learning is accepting applications for the Landmarks of American History and Culture and Summer Institutes program. The purpose of this program is to support humanities education through professional development for K-12 teachers and higher education faculty members.

The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. The purpose of this Notice of Funding Opportunity is to establish the GREGoRi Data Coordination and Outreach Center. The Data Coordination and Outreach Center will act as the central point of coordination for the GREGoRi Research Program, and will be responsible for ensuring that the protocols, data, metadata, computational tools and other resources developed as part of GREGoRi are made available to the broader research community.

This funding opportunity announcement (FOA) encourages applications for institutional research career development (K12) programs that propose to support intensive supervised research training and career development experiences for clinician scientists (Scholars) leading to research independence in the area of substance use and substance use disorder research.

The objective of this funding opportunity is to support investigator-initiated, phase I clinical trials for diagnostic and therapeutic interventions for heart, lung, blood, and sleep (HLBS) disorders in adults and children. The proposed trial can be single or multisite. Applicants applying for funding under this NOFO should be ready to initiate the clinical trial within the first quarter of the project period. Discussion, submission, and attainment of applicable regulatory (FDA, DSMB, IRB) approvals, and establishment of drug (and placebo, if applicable) supplies, and any necessary third-party agreements should be established by the time of award. If time and support for these and other pre-clinical and/or trial readiness activities are desired, applicants should consider the companion NOFO which utilizes an R61/R33 phased approach.

Expected Outcome: The action should contribute to all of the following expected outcomes : The EU climate data and infrastructure sovereignty is strengthened, securing access to essential observation and modelling data for European research community. Effective delivery of climate information relevant for European and global climate policy, including timely contributions to the IPCC assessments and UNFCCC processes. The resilience of the Earth System Grid Federation (ESGF) is strengthened in Europe and globally, and the foundations for an integrated, sustainable long-term operational solution are laid. Scope: The evolution of the geopolitical situation, with the associated changes in science funding priorities and data access policies represent a major threat to evidence-based decision making. The continuity of production, maintenance and open access to climate data, including observations and projections, is fundamental for European and global climate science and policy action. Steps to ensure sustainability and resilience of the strategic resources and infrastructures in Europe needed to deliver these data are imperative. Acting on this offers an opportunity for the EU to…

Supports mathematical research in areas where computation plays a central and essential role, emphasizing analysis, development, and implementation of theoretically justified and efficient algorithms. The combination of these elements resulting in innovative computational methods is a hallmark of the program. Proposals ranging from single investigator to interdisciplinary team projects that not only create and analyze new computational mathematics techniques but also implement them to model, study, and solve important application problems are strongly encouraged, as is providing opportunities for rigorous mathematical training of junior computational mathematicians through research involvement. Conferences Proposals to the Computational Mathematics Program for conferences or workshops must be submitted through the program solicitation "Conferences and Workshops in the Mathematical Sciences" (link below). Principal Investigators should carefully read the solicitation to obtain important information regarding the substance of proposals for conferences, workshops, and similar activities. Unless an exception from the program is granted, to facilitate timely notification of the availability of support, the following requirements are in effect: Proposals for conferences, workshops, etc., to be held in the US must be submitted at least 6 months in advance of the conference start date; Proposals to support group travel to meetings outside the US must be submitted at least 8 months in advance of the meeting start date; Proposals for conferences, workshops, etc., whose budget request exceeds $50,000 must be submitted during the annual Computational Mathematics Program submission window. Conference proposals to the Computational Mathematics Program whose submission dates do not conform with the requirements described above will be returned without review.

Expected Outcome: Proposals should describe a credible pathway from their project results and outcomes towards the expected impact of this Destination; Enable the acceleration of the market uptake of groundbreaking innovations in the decarbonisation of the chemical industries as well as alternatives to substances of concern. Scope: This open topic aims to speed up the adoption of new, groundbreaking innovations (starting TRL 4 ) as part of the Chemical Industry Action Plan, in the areas of decarbonisation of energy intensive industries, circular economy or breakthrough production technologies; as well as development of alternatives (new chemical substances, advanced materials or technologies) to substances of concern. Application of the SSbD Framework should be considered as appropriate.

Expected Outcome: Proposals should demonstrate the following expected outcomes: A sound understanding of the specific needs of industrial users (including but not limited to innovative SMEs, startups and scaleups) for Technology infrastructure services in specific priority areas including but not limited to advanced materials, clean energy, or health and biotechnology; Increased opportunities for industrial users for development, testing, up-scaling and deployment of new technologies via the use of services offered by Technology Infrastructures; Strengthened innovation and technology development capacity of European SMEs, startups and scaleups via improved access to Technology Infrastructures; Attractiveness and effectiveness of the developed access schemes for broadening the range of Technology Infrastructures users, especially for startups and scaleups, including with transnational access. Scope: Startups, scaleups and other innovative SMEs require access to state-of-the-art research and technology facilities, equipment and expertise to test, upscale, validate new products and technologies, shortening the time-to-market and increasing the chances for a successful…

The purpose of this initiative is to: (1) support the efforts by R15-eligible Principal Investigators (PIs) to conduct rigorous basic and/or mechanistic pain research projects; (2) promote integrated, interdisciplinary research partnerships between R15-eligible PIs and additional investigators from U.S. domestic institutions, and (3) enhance the pain research environment at the R15-eligible institution for health professional trainees or undergraduate and/or graduate students by actively engaging them in the proposed pain research projects.

Expected Outcome: Proposals should describe a credible pathway from their project results and outcomes towards the expected impact of this Destination; Proposals should enable open-ended breakthrough innovations in industrial technologies, feeding the pipeline of knowledge. Scope: This is an open topic, intended to cover breakthrough innovations, up to TRL 4, within the scope of the Strategic Research and Innovation Agendas (SRIAs) of the partnerships Made in Europe, Process4Planet, Clean Steel, Innovative Advanced Materials for the EU (IAM4EU) and Textiles for the Future. [1] Proposals should carefully describe their expected contribution to one or more of the R&I objectives of the respective SRIA. [1] https://research-and-innovation.ec.europa.eu/funding/funding-opportunities/funding-programmes-and-open-calls/horizon-europe/european-partnerships-horizon-europe/digital-industry-and-space_en

The World Trade Center (WTC) Health Program supports exploratory and developmental research projects (R21) that address issues related to diagnostic or treatment uncertainty among individuals receiving monitoring and/or treatment under Subtitle C of the James Zadroga 9/11 Health and Compensation Act of 2010, as amended. This R21 Notice of Funding Opportunity (NOFO) is intended to encourage exploratory/developmental research by supporting the early and conceptual stages of project development to assess the feasibility of new areas of investigation with the potential to improve treatment effectiveness and diagnostic practices. These studies may lead to breakthroughs in a particular area or to the development of new interventions, techniques, agents, methodologies, models, or approaches with potential clinical impact. They are expected to break new ground or extend prior discoveries in new directions or applications. Applicants are expected to propose research for which there is likely to be minimal or no preliminary data.

The National Endowment for the Humanities (NEH) Division of Collections & Infrastructure is accepting applications for Collections Stewardship, a program to advance the preservation and availability of physical and digital collections important for research, teaching, and public engagement in the humanities. Planning and implementation projects may include conservation and preservation; digitization and description; enhancement of long-standing digital resources in the humanities; and preservation services or education and training for students and professionals in collections stewardship.

This is a notice of funding opportunity (NOFO) for the OJJDP FY 2026 Strengthening Internet Crimes Against Children (ICAC)Technological Investigative Capacity program. This opportunity will increase the technological investigative capacity and associated training of ICAC task force personnel nationwide through the development, refinement, and advancement of widely used investigative tools, methods, and technologies that address child sexual abuse material (CSAM), exploitation, and sex trafficking.

This notice of funding opportunity (NOFO) invites applications for investigator-initiated clinical trials of complementary and integrative health approaches with physical and/or psychological therapeutic inputs (often called mind and body interventions) in NCCIH-designated areas of high research priority. Applications submitted under this NOFO are expected to propose a multisite feasibility clinical trial that will provide new information that is scientifically necessary for the planning and conduct of a subsequent clinical efficacy or effectiveness study, pragmatic trial, or dissemination and implementation trial within NCCIHs mission. NCCIH expects that applications to this NOFO will describe the planned future clinical trial and in so doing demonstrate that the proposed (R01) research is scientifically necessary to design or plan the subsequent fully powered, full-scale clinical trial. Under this R01, the data collected should be used to fill gaps in scientific knowledge, including, but not limited to the following: assessing whether the intervention can be delivered with fidelity across sites; demonstrating feasibility of recruitment, accrual, and randomization of participants across sites; demonstrating participant adherence to the intervention, as well as retention of participants throughout the study across sites; refining and assessing the feasibility of protocolized multimodal interventions, and/or demonstrating feasibility of data collection across sites in preparation for a future fully powered, multisite efficacy or effectiveness trial. The need for multisite feasibility trials is expected to be justified by sufficient preliminary data from previous single site feasibility or acceptability trial(s) or the published literature. The data collected should be used to fill gaps in scientific knowledge and be necessary to develop a competitive fully powered multisite clinical trial that has the potential to make a significant impact on public health.

This is a notice of funding opportunity (NOFO) for the BJA FY 2026 Upholding the Rule of Law and Preventing Wrongful Convictions Program. This opportunity strengthens the capacity of wrongful conviction review (WCR) entities and their criminal justice and victims’ services partners to more effectively and efficiently identify, assess, and manage post-conviction claims of innocence. Additionally, it aims to enhance public safety by preventing future errors, identifying actual perpetrators of crimes, and delivering justice to victims.

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to stimulate translation of scientific discoveries and engineering developments in imaging, data science and/or spectroscopic technologies into methods or tools that address contemporary problems in understanding the fundamental biology, potential risk of development, diagnosis, treatment, and/or disease status for cancer or other disease.

The John H. Prescott Marine Mammal Rescue and Response Grant Program (Prescott program) provides financial assistance to eligible marine mammal stranding participants and stranding network collaborators to provide (A) the recovery, care, or treatment of sick, injured, or entangled marine mammals; (B) responses to marine mammal stranding events that require emergency assistance; (C) the collection of data and samples from living or dead stranded marine mammals for scientific research or assessments regarding marine mammal health; (D) facility operating costs that are directly related to activities described in (A), (B), or (C); and (E) development of stranding network capacity, including training for emergency response, where facilities do not exist or are sparse. Successful applications will be those aimed at helping support these actions. The U.S. Fish and Wildlife Service’s (FWS) Prescott Grant Program will provide support for response to the stranding of wild populations of species under the Department of the Interior’s management authority per section 3(12) of the Marine Mammal Protection Act (MMPA). Under this Funding Opportunity, FWS will recommend projects for funding based on how well and to what extent they support the species-specific priority activities, which are listed below under Species-Specific Funding Priorities. For the purposes of this program, priority is to be given to applications focusing on marine mammal strandings.

The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. This Notice of Funding Opportunity is intended to stimulate the development and testing of highly innovative experimental or computational approaches for rare disease diagnosis, that have the potential to make transformative improvements to the current state of the art.

Through this Notice of Funding Opportunity, the National Cancer Institute (NCI) seeks research projects that implement early phase (Phase 0, I, and II) investigator-initiated clinical trials focused on cancer-targeted diagnostic and therapeutic interventions of direct relevance to the research mission of DCTD and OHAM. The proposed project must involve at least 1 clinical trial related to the scientific interests of one or more of the following research programs: Cancer Therapy Evaluation Program, Cancer Imaging Program, Cancer Diagnosis Program, Radiation Research Program, Complementary and Alternative Medicine Program and/or the HIV and AIDS Malignancies Research Programs. Applicants may propose to conduct an early phase trial by itself, or in combination with another research aim(s) as appropriate.

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) invites grant applications proposing exploratory research projects focused on further development and technical validation of emerging technologies offering novel capabilities for the molecular or cellular characterization of cancer or for improved handling and quality control of biospecimens used for basic, clinical, or epidemiological cancer research. This NOFO solicits R33 applications where major feasibility gaps for the technology or methodology have been overcome, as demonstrated with supportive preliminary data, but still require further development and rigorous technical validation to encourage adoption by the research community. Well-suited applications must propose the development of technologies that offer the potential to accelerate and/or enhance research in the areas of cancer biology, early detection and screening, clinical diagnosis, treatment, cancer control, epidemiology. Technologies proposed for development may have potential for widespread applicability but must be focused in this proposal on cancer-relevant use cases. Projects proposing to apply or use existing technologies for hypothesis-driven research where the novelty resides in the biological or clinical target/question being pursued are not responsive to this solicitation and will not be reviewed.This funding opportunity is part of a broader NCI-sponsored Innovative Molecular Analysis Technologies (IMAT) Program.

This Notice of Funding Opportunity (NOFO) invites applications from institutions/organizations that propose to establish core centers that are part of an integrated and existing program of nutrition and/or obesity research. The Nutrition Obesity Research Centers (NORC) program is designed to support and enhance the national research effort in nutrition and obesity. NORCs support three primary research-related activities: Research Core services, a Pilot and Feasibility (P and F) program, and a Scientific Catalyst program. All activities pursued by Nutrition Obesity Research Centers are designed to enhance the efficiency, productivity, effectiveness, and multidisciplinary nature of research in nutrition and obesity.

Synopsis of Program: The fields of science, technology, engineering, and mathematics (STEM) hold much promise as sectors of the economy where we can expect to see continuous vigorous growth in the coming decades. STEM job creation is expected to outpace non-STEM job creation significantly, according to the Commerce Department, reflecting the importance of STEM knowledge to the US economy. The National Science Foundation (NSF) plays a leadership role in developing and implementing efforts to enhance and improve STEM education in the United States. Through the NSF  Improving Undergraduate STEM Education  (IUSE) initiative, the agency continues to make a substantial commitment to the highest caliber undergraduate STEM education through a Foundation-wide framework of investments. The IUSE: EDU is a core NSF STEM education program that seeks to promote novel, creative, and transformative approaches to generating and using new knowledge about STEM teaching and learning to improve STEM education for undergraduate students. The program is open to application from all institutions of higher education and associated organizations. NSF places high value on educating students to be leaders and innovators in emerging and rapidly changing STEM fields as well as educating a scientifically literate public. In pursuit of this goal, IUSE: EDU supports projects that seek to bring recent advances in STEM knowledge into undergraduate education, that adapt, improve, and incorporate evidence-based practices into STEM teaching and learning, and that lay the groundwork for institutional improvement in STEM education. In addition to innovative work at the frontier of STEM education, this program also encourages replication of research studies to produce deeper knowledge about the effectiveness and transferability of findings. IIUSE: EDU also seeks to support projects that have high potential for broader societal impacts, including professional development for instructors to ensure adoption of new and effective pedagogical techniques that meet the changing needs of students, and projects that promote institutional partnerships for collaborative research and development. For all the above objectives, the National Science Foundation invests primarily in evidence-based and knowledge-generating approaches to understand and improve STEM learning and learning environments and prepare STEM majors for the workforce. In addition to contributing to STEM education in the host institution(s), proposals should have the promise of adding more broadly to our understanding of effective teaching and learning practices. The IUSE: EDU program features two tracks: (1) Engaged Student Learning and (2) Institutional and Community Transformation. 

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits applications for research on novel therapies for adult glioblastoma (GBM). The goal is to improve the treatment of adult GBM by developing novel effective agents that can cross the blood brain barrier (BBB) and testing them clinically. Successful early-stage trials of new drugs from this NOFO would transition seamlessly to later stage trials using well-established NCI clinical trial mechanisms. To implement this concept, a highly collaborative GBM Therapeutics Network (GTN) of cross-cutting teams will be established, each team capable of driving therapeutic agent(s) from pre-clinical development, through investigational new drugs (IND) studies, into pilot clinical studies in humans. Appropriate therapeutic agents include: (1) novel agents or (2) agents or combinations approved for other indications and repurposed for treatment of GBM following appropriate preclinical studies. The scope of the NOFO, from late pre-clinical through early (Phase 0/1) clinical studies, uniquely spans a gap in the GBM drug development process.

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated, early phase, clinical trials of natural products (i.e., botanicals, probiotics, and products marketed as dietary supplements), which have a strong scientific premise to justify further clinical testing. For this NOFO, natural products include promising nutritional regimens that standardize the amount of a specific naturally occurring nutritional compound (e.g., omega-3 fatty acids, anthocyanidins, or polyphenols) and have compelling preliminary evidence. Under this NOFO, trials must be designed so that results, whether positive or negative, will provide information of high scientific utility and will support decisions about further development or testing of the natural product. This NOFO will provide up to three years (R61 phase) of support for milestone-driven testing of pharmacokinetics, bioavailability, and assessment of the natural products effect (i.e., measure of mechanism of action) when used by humans on a specified target measure. If milestones in the R61 phase are achieved, up to 3 years of additional support (R33 phase) may be awarded to replicate the impact of the natural product on target engagement(s) when used by humans and assess whether there is an association between the degree of the impact on the target engagement and clinical outcomes in a participant population. Applications are encouraged to design R33 studies to determine how to optimize the impact of the natural product on the target engagement by optimizing the delivery of the natural product through examination of different doses or formulations. In addition, applications can be designed to combine the natural product with another treatment approach that is known to impact the same target engagement measure; or study the impact of the natural product in a population that is more responsive,

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) supports a broad-based Alcohol Research Centers program to foster and conduct interdisciplinary, collaborative research on alcohol misuse, Alcohol Use Disorder (AUD), and alcohol-related problems, and other health-related consequences across the lifespan. The NIAAA Centers Program provides leadership in research, and research methodology development on a wide variety of topics relevant to the Institute's mission. The focus of the NIAAA Centers program should be on generating a critical mass of researchers in a given understudied and/or innovative topic area relevant to the NIAAA mission with an emphasis on interdisciplinary coordination and cooperation among independent researchers and development and mentorship of young investigators. A center must contribute more to the alcohol field than the sum of its parts. Topics include but are not limited to, the nature, etiology, genetics, diagnosis, treatment, and prevention of alcohol misuse, AUD, alcohol-related end-organ diseases, and their biomedical, psychosocial, and population health consequences across the lifespan. Centers are also major contributors to the development of research methods, technologies, and approaches that sustain innovative goal-directed research on understanding the chronic disorder of alcohol misuse that is such a personal, social and medical burden to US society.

NOAA/National Marine Fisheries Service’s (NMFS) Marine Mammal Health and Stranding Response Program (MMHSRP) is authorized under the Marine Mammal Protection Act (MMPA) to facilitate collecting and disseminating reference data on stranded marine mammals (cetaceans and pinnipeds, excluding walrus) and the health trends of marine mammal populations in the wild. The John H. Prescott Marine Mammal Rescue Assistance Grant Program is administered by NMFS to provide federal assistance to eligible members of the U.S. National Marine Mammal Stranding Network, the U.S. National Entanglement Response Network, and their collaborators to provide for: (A) the recovery, care, or treatment of sick, injured, or entangled marine mammals; (B) responses to marine mammal stranding events that require emergency assistance; (C) the collection of data and samples from living or dead stranded marine mammals for scientific research or assessments regarding marine mammal health; (D) facility operating costs that are directly related to activities described in (A), (B), or (C); and (E) development of stranding network capacity, including training for emergency response, where facilities do not exist or are sparse. This document describes how to submit proposals for funding under this competition and how NMFS will review and determine which proposals are selected for funding. 

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) along with other participating Institutes encourages submission of applications proposing to conduct secondary data analysis and integration of existing datasets and database resources, with the ultimate aim to elucidate cancer risk and related outcomes (e.g., risk prediction or reduction, survival, or response to treatment, etc.). The goal of this initiative is to address key scientific questions relevant to cancer by supporting the analysis of existing clinical, environmental, surveillance, health services, vital statistics, behavioral, lifestyle, genomic, and molecular profiles data. Applicants are encouraged to leverage and perform innovative analyses of the existing data. Applications may include new research aims that are being addressed with existing data, new or advanced methods of analyses, or novel combinations and integration of datasets that allow the exploration of important scientific questions in cancer research.

Expected Outcome: Excellence Hubs allow innovation ecosystems in Widening countries and beyond, to team up and create better linkages between academia, business, government and society. This will foster a place-based innovation culture in Widening countries based on a strategic agenda aligned with regional or national smart specialisation strategies, and clearly identified expectations for economic and societal impacts. Projects should contribute to the following outcomes: Excellent and sustainable regional R&I ecosystems in Widening countries and beyond in relevant domains of cutting-edge science and innovation; Long term joint R&I strategies underpinned by concrete action plans of European relevance; Common investment plans for R&I, including infrastructures, leveraging national, regional and European funds as well as private capital in a synergetic manner; R&I pilot projects alongside a joint strategy and in line with regional and national strategies, notably regional innovation strategies for smart specialisation (RIS3); New competencies and skills for researchers, entrepreneurs and professionals in R&I intensive domains; Strengthened linkages between science, businesses and…

This Notice of Funding Opportunity (NOFO) invites applications for Diabetes Research Centers (DRCs) that are designed to support and enhance the national research effort in diabetes, its complications, and related endocrine and metabolic diseases. The purpose of this Centers program is to bring together basic and clinical investigators to enhance communication, multidisciplinary collaboration, and effectiveness of ongoing research in Diabetes Research Center topic areas. By providing shared access to specialized technical resources (research cores) and supporting a Pilot and Feasibility Program (P&F), DRCs are intended to create an environment that provides the capability for accomplishments greater than those that would be possible by individual research project grant support alone. New Center programs that bring in diverse perspectives, propose unique scientific themes, or provide innovative resources are encouraged. Emphasis will be placed on Center programs that propose enhanced synergies with other NIDDK-funded programs as well as providing a rich mentoring environment for future diabetes researchers.

Expected Outcome: Projects are expected to contribute to the following outcomes: Raised awareness of venture builders’ roles as part of the ecosystem of startup support in research performing organisations, including universities, Research and Technology Organisations and research and technology infrastructures; Upscaling or establishment of venture builders’ roles in research performing organisations; and Enhanced capacity for sharing resources supporting venture building, exchanging best practices and developing skills needed for successful venture building undertakings in research performing organisations, leading to increased commercialisation of research results (from lab to market). Scope: A variety of organisations across Europe support start up and spin off creation, including incubators, accelerators, innovation hubs, science parks and others. Within this ecosystem, venture builders emerge as playing a double role: on the one hand in building the start-up, drawing on innovative ideas and new technologies at very early stage and bringing together the founding team to create the start up; and on the other hand in providing the support needed to enable the start up to launch…

This Notice of Funding Opportunity (NOFO) invites applications for advanced development and enhancement of emerging informatics technologies to improve the acquisition, analysis, visualization, and interpretation of data across the cancer research continuum including cancer biology, cancer treatment and diagnosis, early cancer detection, risk assessment and prevention, cancer control and epidemiology. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Program, this NOFO is focused on advancing emerging informatics technology, defined as one that has passed the initial prototyping and pilot development stage, has demonstrated potential to have a significant and broader impact, has compelling reasons for further improvement and enhancement, and has not been widely adopted in the cancer research field. To be successful, proposed development plans must have a clear rationale for why the proposed technology is needed and how it will benefit the cancer research field. In addition, mechanisms to solicit feedback from driving cancer research projects as well as the broader user community throughout the development process must be included.This NOFO invites applications for the enhancement and dissemination of emerging, user-friendly informatics technologies that support a wide range of cancer research, including discovery biology, population studies, as well as clinical and translational research. The emphasis is on uniqueness and potential impact on cancer research. In addition, all projects proposed in response to this NOFO must involve the following general attributes:Potential to advance driving cancer research projects and the cancer research field in general;Offers clear advantages over competing technologies in the targeted cancer research domain;Provides compelling plans and processes for supporting and engaging end users to evaluate and apply the tool or resource;Provides plans for advancing use of the tool or resource by the targeted community through collaboration, outreach, and training;Provides a realistic timeline and milestones for technology development.

This Notice of Funding Opportunity (NOFO) solicits applications for the continued development and sustainment of high value informatics research resources to improve the acquisition, management, analysis, and dissemination of data and knowledge across the cancer research continuum including cancer biology, cancer treatment and diagnosis, early cancer detection, risk assessment and prevention, cancer control and epidemiology. As a component of the NCI's Informatics Technology for Cancer Research ( ITCR ) Program, this NOFO is focused on sustaining operations and maintaining and evolving the scientific relevance of existing, widely-adopted informatics tools and resources. This is in contrast to early-stage and advanced development efforts to generate these tools and resources that will be supported by companion ITCR NOFOs. The central mission of ITCR is to promote research-driven informatics technology across the development lifecycle to address priority needs in cancer research. In order to be successful, the application must provide clear justification for why the research resource should be maintained and how it has benefited and will continue to benefit the cancer research field. In addition, mechanisms for assessing and maximizing the value of the resource to researchers and supporting close engagement between the resource and the targeted research community should be described. This NOFO invites applications to support the sustained operations of informatics technology resources that support a wide range of cancer research, including discovery biology, population studies, as well as clinical and translational research. The emphasis is on sustaining resources that have had a demonstrated impact on cancer research. In addition, all projects proposed in response to this NOFO must involve the following general attributes: Evidence that the technology has had significant impact on cancer research to date and the sustainment plan will lead to the continued advancement of cancer research Robust plans for supporting the end-user community including documentation, training, and other outreach activities Clear processes for engaging end users to address emerging needs of the targeted research communities to ensure that the research resource maintains relevance to the research it supports

The primary objective of the program is to provide grants to Agriculture Innovation Centers that will provide technical assistance to agricultural producers to market value-added agricultural products.

The objective of the program is to provide a basis for advancing science-based fisheries management for Atlantic bluefin tuna. Such advancement will depend upon improvements in understanding of the fisheries, total abundance, and biology of bluefin tuna, especially regarding the effects of mixing and movement between the eastern and western Atlantic populations. Contracting Parties to the International Commission for the Conservation of Atlantic Tunas (ICCAT), of which the US is one, and other partners have embarked upon a multi-year research program on bluefin tuna as a step toward improving ICCAT's science-based management of Bluefin fisheries. Research sponsored under this funding opportunity represents a contribution to this partnership. Proposals that demonstrate collaborations with the ICCAT Atlantic Bluefin Tuna Research Program and other ICCAT partners are strongly encouraged.

Expected Outcome: Enhanced valorisation of intellectual assets, including dormant patents, from universities and public research organisations to support the adoption of green and digital technologies by industry, SMEs and start-ups/spinoffs. Development of entrepreneurial skills and increased involvement of students, researchers, and innovators in the valorisation of research results. Uptake of effective models and tools to facilitate valorisation of unused IP and intellectual assets and access by startups, SMEs, and innovative companies to this untapped knowledge in public research organisations. Scope: Aligned with the European Union's policy priorities, this action will contribute to overcoming the innovation paradox by maximising the impact of public spending in R&I through improved knowledge valorisation practices, and facilitating the uptake of green and digital technologies by start-ups, spinoffs, and innovative SMEs. By unlocking the untapped potential of intellectual assets within universities and public research organisations, and leveraging the creativity of students, researchers, and innovators, the action seeks to improve value creation opportunities deriving from…

Expected Outcome: Project are expected to contribute to the following outcomes: a sustainable operational model and reference blueprint for a Data Lab for Science linking with the European Open Science Cloud (EOSC) and the Resource for AI Science in Europe (RAISE), enabling researchers to accelerate the uptake of AI in Science; easier access for researchers to large amounts of AI-ready research data, and to associated high-quality data services to seamlessly develop and train AI models for science; and better alignment, interoperability and scaling across countries and disciplines of AI workflows and related services such as data pooling, anonymisation, curation, or synthetic data generation. Scope: Data Labs are introduced in the Data Union Strategy as a connector between AI factories and the Common European Data Spaces, providing specialised services to enable turning data into useable resources for AI training and the development of AI applications such as data pooling, curation, pseudonymisation, and synthetic data generation. A significant number of tools and services within the scope of the Data Lab concept have been developed by research infrastructures and scientific…

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) along with other participating Institutes encourages submission of applications proposing to conduct secondary data analysis and integration of existing datasets and database resources, with the ultimate aim to elucidate cancer risk and related outcomes (e.g., risk prediction or reduction, survival, or response to treatment, etc.). The goal of this initiative is to address key scientific questions relevant to cancer by supporting the analysis of existing clinical, environmental, surveillance, health services, vital statistics, behavioral, lifestyle, genomic, and molecular profiles data. Applicants are encouraged to leverage and perform innovative analyses of the existing data. Applications may include new research aims that are being addressed with existing data, new or advanced methods of analyses, or novel combinations and integration of datasets that allow the exploration of important scientific questions in cancer research.

Awarded activities will facilitate the translation of novel recording and modulation technologies that can be used to treat and/or diagnose central nervous system (CNS) diseases and disorders and to better understand the human CNS, from proof of concept up to the stage of readiness for first in human (FIH) studies. Technologies may incorporate any signal modality (e.g., electrical, optical, magnetic, acoustic) or a combination thereof. Diverse team-based applications that integrate appropriate domains of expertise are encouraged.

The Human Networks and Data Science program (HNDS) supports research that enhances understanding of human behavior by leveraging data and network science research across a broad range of topics. HNDS research will identify ways in which dynamic, distributed, or heterogeneous data can provide novel answers to fundamental questions about individual or group behavior. HNDS is especially interested in proposals that provide data-rich insights about human networks to support improved health, prosperity, and security. HNDS has two tracks: (1) Human Networks and Data Science – Infrastructure (HNDS-I). Infrastructure proposals will address the development of data resources and relevant analytic techniques that support fundamental Social, Behavioral and Economic (SBE) research. Successful infrastructure proposals will construct, within the financial resources provided by the award, databases or relevant analytic techniques and produce a finished product that will enable previously impossible data-intensive research in the social sciences. The databases or techniques should have significant impacts, either across multiple fields or within broad disciplinary areas, by making possible new types of data-intensive research in the SBE sciences. (2) Human Networks and Data Science – Core Research (HNDS-R). Core research proposals will advance theory in a core SBE discipline by the application of data and network science methods. This includes the leveraging of large data sets with diverse spatio-temporal scales of measurement and linked qualitative and quantitative approaches, as well as multi-scale, multi-level network data and techniques of network analysis. Supported projects are expected to yield results that will enhance, expand, and transform theory and methods, and that generate novel understandings of human behavior – particularly understandings that can lead to significant societal benefits or opportunities. HNDS-R encourages core research proposals that make innovative use of NSF-supported data networks, databases, centers and other forms of scientific infrastructure including those developed by HNDS-I (formerly RIDIR) projects .

Expected Impact: The prize will boost public awareness of the potential, importance and contribution of women to the EU innovation ecosystem and create strong role models, inspiring more women to become innovators themselves. Expected Outcome: The prize will boost public awareness of the potential, importance and contribution of women to the EU innovation ecosystem and create strong role models, inspiring more women to become innovators themselves. Objective: The European Prize for Women Innovators celebrates the women entrepreneurs behind Europe’s game-changing innovations, so that they may inspire other women and girls realise their full potential as the EU’s future scientists, innovators, and tech leaders. This prize supports a culture within research and innovation organisations and companies allowing women to become the innovators and entrepreneurs of tomorrow. The prize is awarded every year to women from across the EU and countries associated to Horizon Europe, who have transformed their ideas into disruptive innovations to benefit people and the planet and who are inspiring leaders. As for the previous edition, the 2027 European Prize for Women Innovators is organised in…

The Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program aims to promote broad participation in the biomedical research ecosystem by supporting resource limited organizations to conduct research, enhance the research environment, and increase sponsored programs administration capacity.This program intends to support eligible, domestic organizations with limited research resources and few biomedical doctoral students.

The National Aeronautics and Space Administration (NASA) Headquarters anticipates release of a solicitation, titled “NASA Innovative Advanced Concepts (NIAC), Phase I,” as an Appendix to the Space Technology Mission Directorate (STMD) NASA Research Announcement (NRA), titled “Space Technology Research, Development, Demonstration, and Infusion - 2026 (SpaceTech-REDDI-2026),” on or about September 28, 2026 . Once the Appendix is posted, complete details (to include due dates) can be accessed via the following steps:   1. Open the NSPIRES homepage at https://nspires.nasaprs.com/ 2. Select "Solicitations" 3. Select "Open” 4. Select "Space Technology Research, Development, Demonstration, and Infusion - 2026 (SpaceTech-REDDI-2026) NNH26ZTR001N” 5. Select “List of Open Program Elements” 6. Select “NASA Innovative Advanced Concepts (NIAC), Phase I- NNH26ZTR001N-27NIAC_A1" 7. Select “NASA Innovative Advanced Concepts (NIAC) Phase I Solicitation Document" under Announcement Documents.   The NASA Innovative Advanced Concepts (NIAC) Program supports innovative research through multiple Phases of awards. Phase I awards are typically a nine-month effort to explore the overall feasibility and viability of visionary concepts. There are two steps to the Phase I proposal process; a brief Step A proposal open to all eligible applicants, and an expanded Step B for those who are invited.   All categories of U.S organizations may apply to Appendix NNH26ZTR001N-27NIAC_A1. NIAC Principal Investigators (PIs), also known as NIAC Fellows, and team members may be affiliated with any type of U.S organization. Non-U.S. organizations may partner in, or lead, NIAC studies on a no-exchange of funds basis, and subject to NASA’s policy on foreign participation (see Section B.3 of SpaceTech-REDDI-2026).   All proposals must be submitted electronically through NSPIRES by an authorized organizational representative (AOR). Detailed submission instructions are provided in the SpaceTech-REDDI-2026 NRA, as well as the NASA Grant and Cooperative Agreement Manual available here:  https://www.nasa.gov/grants-operations-management/ . Potential proposers and their proposing organizations are urged to familiarize themselves with the submission system, ensure they are registered in NSPIRES, and submit the required proposal materials well in advance of the deadline.   Please note that registration in NSPIRES cannot be completed until each applicable institution obtains a Unique Entity Identifier (UEI) (previously Data Universal Number (DUNS)), obtains a Commercial and Government Entity (CAGE) code, and registers in the System for Award Management (SAM). Please provide sufficient time to ensure completion of this step prior to the submission deadlines.   NIAC will host a virtual forum that will address key aspects of this Phase I Appendix. The date and time for this forum is October 7, 2026 from 1-3PM ET. The agenda for the virtual forum and other related information and material, including the link information, will be posted on the NASA Solicitation and Proposal Integrated Review and Evaluation System (NSPIRES) page for this Appendix ( https://nspires.nasaprs.com/external/ ). Offerors are encouraged to regularly refer to this website for updates and other information relative to this Appendix. Proposers are encouraged to submit their questions regarding this Appendix by close of business on October 6, 2026 to https://nasa.cnf.io/sessions/dbmt or hq-niac@mail.nasa.gov .   Interested proposers should monitor the NSPIRES website or subscribe to the electronic notification system there for release of the SpaceTech-REDDI-2026 Appendices.   Technical, programmatic, and procurement comments and questions may be addressed by e-mail to hq-niac@mail.nasa.gov . Responses to inquiries will be answered by e-mail and may also be included in the Frequently Asked Questions (FAQ) document located on the NSPIRES page associated with the Appendix; anonymity of persons/institutions who submit questions will be preserved.

The purpose of this Notice of Funding Opportunity (NOFO) is to advance the development of novel informatics and data science approaches that can help individuals understand and improve their health through actionable insights. NLM seeks applications that further the science of personal health informatics by providing meaningful and actionable insights to individuals through innovative personal health data collection, integration, analysis, and personalized risk assessments and interpretation. Applications seeking to advance the understanding of how informatics tools, systems, and platforms can best present the results, interpretation, and limitations of personalized assessments for the benefit of individuals are encouraged. Applications should include end user engaged approaches and real-world evaluation to inform the design of generalizable, reusable, and scalable personal health informatics tools, systems, and platforms for the benefit of individuals in understanding and improving their health.

This funding opportunity is part of a suite of NOFOs within the NIH HEAL Initiative to support the development of safe, effective, and non-addictive therapeutics to treat pain. The goal is to encourage initial translational efforts that will support a drug discovery program and advance projects to the point where they meet the entry criteria for the Pain Therapeutics Development Program. The scope will therefore be focused on development of assays to support a distinct testing funnel, screening efforts to identify hits, and initial characterization of hits and potential therapeutic agents (including small molecules, biologics, and natural products).

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute invites applications to the Carcinogen Hazard Assessment Monographs Program (CHAMP) Initiative . NCI seeks meritorious proposals to critically and systematically evaluate the scientific evidence on carcinogenic hazards to humans. Identifying potential carcinogens is essential for guiding and advancing cancer research, as well as informing cancer control and prevention efforts. 

This Notice of Funding Opportunity (NOFO) invites applications for Silvio O. Conte Digestive Diseases Research Core Centers (DDRCCs). The DDRCCs are part of an integrated program of digestive and liver diseases research support provided by the NIDDK. The purpose of this Centers program is to bring together basic and clinical investigators to enhance communication, collaboration, and effectiveness of ongoing research related to digestive and/or liver diseases within the NIDDK's mission. DDRCCs are based on the core concept, whereby shared resources aimed at fostering productivity, synergy, and new research ideas among the funded investigators are supported in a cost-effective manner. Each proposed DDRCC must be organized around a central theme that reflects the focus of the digestive or liver diseases research of the Center members. The central theme must be within the primary mission of the NIDDK, and not thematic areas for which other NIH Institutes or Centers are considered the primary source of NIH funding.

The purpose of this Funding Opportunity Announcement (FOA) is to support high priority research at the intersection of HIV and substance use. This FOA invites innovative research projects with the potential to open new areas of HIV/AIDS research and/or lead to new avenues for prevention, treatment and cure of HIV among people who use drugs (PWUD). Applications submitted under this FOA are required to have a detailed research plan, preliminary data, and a clear description of the nexus with substance use. This FOA is open to both individual researchers and research teams and includes all areas of research from basic science to clinical and implementation research. All studies must focus on NIH HIV/AIDS Research Priorities: NOT-OD-20-018: UPDATE: NIH HIV/AIDS Research Priorities and Guidelines for Determining HIV/AIDS Funding.

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits grant applications proposing to develop innovative technologies offering new capabilities for the molecular or cellular characterization of cancer or for improved handling and quality control of biospecimens for basic, clinical, or epidemiological cancer research. The NOFO solicits R61 applications for early-stage projects proposing proof-of-concept/pilot studies to test the technical feasibility of the proposed method, tool, assay, platform, or instrument. Technologies proposed for development may have potential for widespread applicability but must be focused for this program on cancer-relevant use cases. Projects proposing to apply or use existing technologies for hypothesis-driven research where the novelty resides in the biological or clinical target/question being pursued are not responsive to this solicitation and will not be reviewed.This funding opportunity is part of a broader NCI-sponsored Innovative Molecular Analysis Technologies (IMAT) Program.

This Notice of Funding Opportunity requests pre-proposals, and then later full applications, for the implementation of State and Interstate Aquatic Nuisance Species Management Plans (SIANSMP) that have been approved by the Aquatic Nuisance Species Task Force (ANSTF) as per Section 4724 (b)(3)(a) of the Nonindigenous Aquatic Nuisance Prevention and Control Act of 1990 as amended (16 U.S.C. 4701-4741). These plans identify activities needed to prevent introductions and spread, and eliminate or reduce the risks associated with, aquatic nuisance species, as part of the broader objective of moving towards a nationally coordinated aquatic invasive species program.The grant process includes a pre-proposal review that occurs outside GrantSolutions. After receiving approval of pre-proposals, eligible applicants can complete the full application process within GrantSolutions. The grant program includes a 25% cost-share (of total project costs) and a 5% limit on administrative costs.

Invasive surgical procedures in humans offer the unique opportunity to intracranially record and stimulate neuronal activity within precisely localized brain structures, enabling high-impact human neuroscience investigations. This NOFO seeks exploratory research projects, from newly formed or established multi-disciplinary teams, to understand how dynamic activity of single cells and ensembles of neurons in spatially organized networks gives rise to the internal states we experience as sensations, perceptions, emotions, thoughts, and memories, and to observable motor and social behaviors. The research should be proposed as exploratory research and planning activities to establish feasibility and early-stage development that, if successful, would support, enable, and/or lay the groundwork for a potential, subsequent research project grant applications using invasive neural recording and stimulation technologies in the human brain. Projects should maximize opportunities to conduct innovative in vivo human neuroscience research made available by direct access to the brain from invasive surgical procedures. Projects should employ approaches guided by specified theoretical constructs and by quantitative, mechanistic models where appropriate. Recipients will join a consortium working group, coordinated by the NIH, to identify consensus standards of practice, including neuroethical considerations, to collect and provide data for ancillary studies, and to aggregate and standardize data for dissemination among the wider scientific community.

The National Library of Medicine (NLM) invites applications for innovative predoctoral and postdoctoral training programs that prepare the next generation of researchers in biomedical informatics, data science, and artificial intelligence/machine learning (AI/ML). NLM emphasizes cutting-edge, forward-looking training experiences that equip trainees to address complex health and biomedical challenges through advanced computational approaches. Applications may propose the creation of new training programs or the renewal of existing NLM-supported programs. These programs are designed to meet the growing demand for researchers with deep expertise in biomedical computing, data science, and AI/ML, with clear relevance to health and biomedical research. Recognizing the inherently interdisciplinary nature of these fields, NLM seeks programs that integrate methods and perspectives across disciplines to advance biomedical informatics, data science, and AI/ML.

Expected Impact: The prize will boost public awareness of the potential, importance and contribution of women to the EU innovation ecosystem and create strong role models, inspiring more women to become innovators themselves. Expected Outcome: The prize will boost public awareness of the potential, importance and contribution of women to the EU innovation ecosystem and create strong role models, inspiring more women to become innovators themselves. Objective: The European Prize for Women Innovators celebrates the women entrepreneurs behind Europe’s game-changing innovations, so that they may inspire other women and girls realise their full potential as the EU’s future scientists, innovators, and tech leaders. This prize supports a culture within research and innovation organisations and companies allowing women to become the innovators and entrepreneurs of tomorrow. The prize is awarded every year to women from across the EU and countries associated to Horizon Europe, who have transformed their ideas into disruptive innovations to benefit people and the planet and who are inspiring leaders. As for the previous edition, the 2027 European Prize for Women Innovators is organised in…

This grant program provides competitive grants to non-Federal researchers working to benefit U.S. fishermen and fisheries, including aquaculture, through the development of improved fishing practices and innovative gear technologies. The Magnuson-Stevens Fishery Conservation and Management Act, as amended (MSA), 16 U.S.C. 1865, requires that NOAA’s conservation and management measures minimize bycatch to the extent practicable and established the Bycatch Reduction Engineering Program (BREP) to support the development of technological devices and other conservation engineering changes to minimize bycatch and reduce post-release mortality of non-target species in our nation’s fisheries. Bycatch reduction is a priority for the National Marine Fisheries Service (NMFS), as outlined in the NMFS National Bycatch Reduction Strategy (https://www.fisheries.noaa.gov/national/bycatch/national-bycatchreduction-strategy). Fisheries bycatch can contribute to overfishing, population declines for threatened and endangered species, and can result in commercial fishery closures. This Program seeks to support the development and testing of fishing gears and approaches that can be applied in commercial and recreational fisheries to reduce bycatch and post-release mortality and address the MSA requirements to minimize bycatch and habitat impacts.  

The Common Fund Human Virome Program (HVP) aims to extensively and comprehensively characterize the "healthy" human virome (the collection of viruses that normally reside inside the human body without evidence of disease) and create tools, models, and methods that will enable an in-depth study of its variation and composition in relation to host factors and its influence on health and disease. The purpose of this NOFO is to support small pilot projects that extend the goals of the HVP, including further validating, improving, and complementing existing and newly developed tools from the HVP program by leveraging human specimens collected from the cohorts under the program; samples from animals to promote the refinement, utilization, and translation of these tools to better serve the goals of the HVP program; expanding existing cohorts and/or biospecimen sampling sites for virome characterization; developing tools, assays, and methods to study the human virome; and defining functional interactions between the human virome and host. These pilot projects will expand the HVP consortium, and collaboration across the HVP is expected. Applicants outside the current HVP are encouraged to apply and pilot projects should not overlap with existing HVP efforts (visit the Common Fund website for a list of funded research).

Expected Outcome: Integration of quantum computing into data pre-processing pipelines and learning workflows for data-heavy or computationally intensive tasks, demonstrating clear improvements in processing speed, computational complexity, modelling accuracy, and reduced sample requirements at scales achievable with NISQ-era devices, Reliable and scalable Quantum Machine Learning (QML) models and algorithms, integrated with existing AI frameworks and pipelines, enabling faster data processing, improved prediction accuracy, and enhanced computational capabilities, Validated quantum-enhanced AI methods demonstrating measurable improvements over classical baselines in terms of speed, accuracy, data efficiency, complexity, or scalability, supported by rigorous benchmarking and complexity analysis, Robust, noise-aware QML techniques suitable for NISQ hardware , including error-mitigation strategies and algorithmic adaptations that improve reliability, performance, and reproducibility on real quantum processors, Demonstrators or proof-of-concept applications showcasing the relevance of QML for real-world challenges (e.g. climate and environmental modelling, Earth observation, healthcare…

The ROSS Rapid Response Program (RRP) awards one-time assistance via a cost-reimbursable grant for service coordination and limited direct services for residents of HUD-assisted housing. The RRP utilizes a simplified application process to promote local leadership and flexibility in addressing urgent social needs caused by unanticipated emergencies. Examples of these emergencies can include but are not limited to: • Natural disasters (e.g., wildfires or hurricanes) • Public health crises (e.g., gun violence, community-level contamination or environmental hazards) • Economic disruptions (e.g., closure of a major employment center that employs residents at the target site)

The purpose of this Notice of Funding Opportunity (NOFO) is to invite Small Research Grant (R21) applications that propose to study the ethical, legal, and social implications (ELSI) of human genetics and genomics. Applications may propose studies using either single or mixed methods. Direct involvement of key stakeholders where appropriate is encouraged. These applications should be for small research projects, such as those that involve single investigators. Of particular interest are projects that propose normative or conceptual analyses, including focused legal, economic, philosophical, anthropological, or historical analyses of new or emerging issues. This mechanism can also be used for the collection of preliminary data and the secondary analysis of existing data.

This Notice of Funding Opportunity (NOFO) is issued by the Food and Drug Administration (FDA), Center for Veterinary Medicine (CVM), and solicits Research Project (R01) grant applications from institutions or organizations that propose to develop or support the development of designated new animal drugs intended for minor uses in major species or for use in minor species (MUMS).  The FDA is authorized to provide grants to assist in defraying the costs of qualified safety and effectiveness testing that could be used to satisfy the requirements for FDA approval of MUMS-designated drugs. Only entities developing drugs for veterinary use or parties working as research partners with such entities are eligible for grants. The organization (or applicant) seeking approval of the new animal drug under investigation must have opened an Investigational New Animal Drug (INAD) file with FDA/CVM and must hold a minor use or minor species "designation" granted by FDA/CVM's Office of Minor Use and Minor Species Animal Drug Development (OMUMS) for that drug for a specified intended use, in accordance with the provisions of section 573 of the Food, Drug and Cosmetic Act (21 U.S.C. 360ccc-2) and 21 CFR part 516. FDA/CVM's Office of New Animal Drug Evaluation (ONADE) must have reviewed and concurred with the proposed study protocol before an applicant can submit a grant application.

Apply for an early independence fellowship if your research focus is within EPSRC Mathematical Sciences remit. You must have: a PhD evidence of career consolidation and past productivity plans for establishing your own research niche that enables a step-change towards independence

Expected Outcome: The commercial potential of Horizon research results is explored; Results of Horizon projects are valorised, by ensuring a pathway to commercialisation; and Startups and SMEs become involved in valorisation. Scope: The EU must do better in translating the knowledge generated by the Framework Programme into innovations with economic and societal value. The objective of this action is to provide financial support (‘Proof of market’) to small consortia (i.e. spin-offs, startups, SMEs) to explore the exploitation potential, in the EU, of achieved results from ongoing or completed projects funded under Cluster 4 ‘Digital, Industry and Space’ or its predecessor activities under the Leadership in enabling and industrial technologies (LEIT) [1] part of Horizon 2020. The consortia do not necessarily have to be made of former or current beneficiaries but should own or have access to the knowledge assets of projects, including intellectual property, where relevant. Proposals should envisage valorisation activities, such as: demonstrating a technology (e.g. testing); defining a commercialisation process; undertaking: a market and competitiveness analysis; a technology…

The NIH Cardiovascular Repository for Type 1 Diabetes (CaRe-T1D) was created to improve research on type 1 diabetes (T1D) and cardiovascular disease (CVD). Cardiovascular complications remain the top cause of death among people with T1D and greatly shorten lifespan. The mechanisms underlying atherosclerosis, cardiomyopathy, endothelial dysfunction, and cardiac autonomic neuropathy in T1D remain poorly understood. While managing traditional risk factors—such as high blood glucose, high blood pressure, and elevated cholesterol lower cardiovascular risk, a significant residual risk remains even with optimal control. In addition to atherosclerosis, both diastolic and systolic diabetic cardiomyopathy play a major role in morbidity and mortality among these patients. Currently, no therapies are specifically approved to prevent or treat these common and severe cardiovascular issues in T1D. The purpose of this NOFO is to promote collaborative and interdisciplinary research aimed at enhancing the understanding of the development of CVD in individuals with T1D and the differences with CVD in T1D by continuing the efforts of the CaRe-T1D consortium.This NOFO is associated with the Special Diabetes Program (https://www.niddk.nih.gov/about-niddk/research-areas/diabetes/type-1-diabetes-special-statutory-funding-program/about-special-diabetes-program) which funds research on the prevention, treatment, and cure of type 1 diabetes and its complications, including unique, innovative, and collaborative research consortia and clinical trials networks.

The Life Sciences Transformational R&D Investment Fund Pilot offers capital grants to support large-scale R&D projects in the UK life sciences sector (eligible projects must exceed £100 million in total costs). It aims to boost research and development within the UK's Life Sciences sector by supporting large-scale investments focused on innovation and strengthening health resilience, as well as projects with the potential to generate economic benefits. This fund complements the separate Life Sciences Innovative Manufacturing Fund (LSIMF).

The goal of this program is to support collaborative translational research projects aligned with NIH efforts to enhance the translation of basic biological discoveries into clinical applications that improve health. It encourages high quality science demonstrating the potential to result in understanding an important disease process or lead to new therapeutic interventions, diagnostics, or prevention strategies within the research interests and priorities of the participating NIH Institutes/Centers (ICs).Specifically, the program seeks to broaden and strengthen translational research collaborations between basic and clinical researchers both within and outside NIH to accelerate and enhance translational science by promoting partnerships between NIH intramural investigators (e.g., those conducting research within the labs and clinics of the NIH) and extramural investigators (e.g., those conducting research in labs outside the NIH), and by providing support for extramural investigators to take advantage of the unique research opportunities available at the NIH Clinical Center by conducting clinical research projects in collaboration with NIH intramural investigators.

The National Institute for Occupational Safety and Health (NIOSH), Centers for Disease Control and Prevention (CDC), invites grant applications for Education and Research Centers (ERCs) that are focused on occupational safety and health training. NIOSH is mandated to provide an adequate supply of qualified personnel to carry out the purposes of the Occupational Safety and Health Act, and the ERCs are one of the primary means for meeting this mandate. ERCs are academic institutions that provide high-quality interdisciplinary graduate and post-graduate training, research training, continuing education, and outreach in the core occupational safety and health disciplines of industrial hygiene, occupational health nursing, occupational medicine, and occupational safety, as well as allied disciplines. Research and research training are integral components of ERCs, with ERC faculty and NIOSH trainees conducting research on issues related to the NIOSH National Occupational Research Agenda (NORA) and emerging issues to advance the field of occupational safety and health. NIOSH ERCs have regional presence to further diversify the occupational safety and health profession through their core values, mission statements, and outputs. ERCs serve as resources for our nation's workforce through continuing education, outreach and strong collaboration with professional associations, worker advocacy groups, businesses, industries, and public health agencies. ERCs work with other institutions and organizations, including Minority Serving Institutions and other NIOSH supported training programs to have a positive impact on worker health, safety, and well-being.

This NOFO is modified. Changes are made to Step 1: Review the Opportunity. The Office of Refugee Resettlement (ORR) provides temporary housing and care for children who arrive in the United States alone. These are children who are under 18 years old, don't have legal permission to be in the U.S., and don't have a parent or legal guardian in the U.S. who can take care of them. ORR runs the Home Study and Post-Release Services Program to help these children. Before placing a child with a sponsor, ORR carefully checks potential homes to make sure they're safe and appropriate. After placement, ORR provides ongoing support to help children and their sponsors succeed. This support helps children adjust to living with their sponsor, connect with their community, stay safe and healthy, and navigate the immigration court process. The goal is to make sure children are placed in safe homes and have the support they need to thrive while their immigration cases move forward.

The purpose of this modification is to clarify the meaning of the Program Policy Factors in Section V.C. To obtain a copy of the Notice of Funding Opportunity (NOFO) please go to the ARPA-E website at https://arpa-e-foa.energy.gov. To apply to this NOFO, Applicants must register with and submit application materials through ARPA-E eXCHANGE ( https://arpa-e-foa.energy.gov/Registration.aspx ). For detailed guidance on using ARPA-E eXCHANGE, please refer to the ARPA-E eXCHANGE User Guide (https://arpa-e-foa.energy.gov/Manuals.aspx). ARPA-E will not review or consider concept papers submitted through other means. For problems with ARPA-E eXCHANGE, email ExchangeHelp@hq.doe.gov (with NOFO name and number in the subject line). Questions about this NOFO? Check the Frequently Asked Questions available at http://arpa-e.energy.gov/faq . For questions that have not already been answered, email ARPA-E-CO@hq.doe.gov.   AGENCY OVERVIEW The Advanced Research Projects Agency – Energy (ARPA-E), an organization within the Department of Energy (DOE), is chartered by Congress in the America COMPETES Act of 2007 (P.L. 110-69), as amended by the America COMPETES Reauthorization Act of 2010 (P.L. 111-358), as further amended by the Energy Act of 2020 (P.L. 116-260): “(A) to enhance the economic and energy security of the United States through the development of energy technologies that— (i) reduce imports of energy from foreign sources; (ii) reduce energy-related emissions, including greenhouse gases; (iii) improve the energy efficiency of all economic sectors; (iv) provide transformative solutions to improve the management, clean-up, and disposal of radioactive waste and spent nuclear fuel; and (v) improve the resilience, reliability, and security of infrastructure to produce, deliver, and store energy; and (B) to ensure that the United States maintains a technological lead in developing and deploying advanced energy technologies.” ARPA-E issues this Notice of Funding Opportunity (NOFO) under its authorizing statute codified at 42 U.S.C. § 16538. The NOFO and any cooperative agreements or grants made under this NOFO are subject to 2 C.F.R. Part 200 as supplemented by 2 C.F.R. Part 910. ARPA-E funds research on, and the development of, transformative science and technology solutions to address the energy and environmental missions of the Department. The agency focuses on technologies that can be meaningfully advanced with a modest investment over a defined period of time in order to catalyze the translation from scientific discovery to early-stage technology. For the latest news and information about ARPA-E, its programs and the research projects currently supported, see: http://arpa-e.energy.gov/. ARPA-E funds transformational research. Existing energy technologies generally progress on established “learning curves” where refinements to a technology and the economies of scale that accrue as manufacturing and distribution develop drive improvements to the cost/performance metric in a gradual fashion. This continual improvement of a technology is important to its increased commercial deployment and is appropriately the focus of the private sector or the applied technology offices within DOE. In contrast, ARPA-E supports transformative research that has the potential to create fundamentally new learning curves. ARPA-E technology projects typically start with cost/performance estimates well above the level of an incumbent technology. Given the high risk inherent in these projects, many will fail to progress, but some may succeed in generating a new learning curve with a projected cost/performance metric that is significantly better than that of the incumbent technology. ARPA-E will provide support at the highest funding level only for submissions with significant technology risk, aggressive timetables, and careful management and mitigation of the associated risks. ARPA-E funds technology with the potential to be disruptive in the marketplace. The mere creation of a new learning curve does not ensure market penetration. Rather, the ultimate value of a technology is determined by the marketplace, and impactful technologies ultimately become disruptive – that is, they are widely adopted and displace existing technologies from the marketplace or create entirely new markets. ARPA-E understands that definitive proof of market disruption takes time, particularly for energy technologies. Therefore, ARPA-E funds the development of technologies that, if technically successful, have clear disruptive potential, e.g., by demonstrating capability for manufacturing at competitive cost and deployment at scale. ARPA-E funds applied research and development (R&D). The Office of Management and Budget defines “applied research” as an “original investigation undertaken in order to acquire new knowledge…directed primarily towards a specific practical aim or objective” and defines “experimental development” as “creative and systematic work, drawing on knowledge gained from research and practical experience, which is directed at producing new products or processes or improving existing products or processes.”0F1 Applicants interested in receiving financial assistance for basic research (defined by the Office of Management and Budget as “experimental or theoretical work undertaken primarily to acquire new knowledge of the underlying foundations of phenomena and observable facts”)1 should contact the DOE’s Office of Science (http://science.energy.gov/). Office of Science national scientific user facilities (http://science.energy.gov/user-facilities/) are open to all researchers, including ARPA-E Applicants and awardees. These facilities provide advanced tools of modern science including accelerators, colliders, supercomputers, light sources and neutron sources, as well as facilities for studying the nanoworld, the environment, and the atmosphere. Projects focused on early-stage R&D for the improvement of technology along defined roadmaps may be more appropriate for support through the DOE applied energy offices including: the Office of Energy Efficiency and Renewable Energy (http://www.eere.energy.gov/), the Office of Fossil Energy and Carbon Management (https://www.energy.gov/fecm/office-fossil-energy-and-carbon-management), the Office of Nuclear Energy (http://www.energy.gov/ne/office-nuclear-energy), and the Office of Electricity (https://www.energy.gov/oe/office-electricity). ARPA-E encourages submissions stemming from ideas that still require proof-of-concept R&D efforts as well as those for which some proof-of-concept demonstration already exists. Submissions can propose a project with the end deliverable being an extremely creative, but partial solution. PROGRAM OVERVIEW The Seeding Critical Advances for Leading Energy technologies with Untapped Potential (SCALEUP) Ready program provides a vital mechanism for the support of innovative energy R&D that complements ARPA-E’s primary focus on early-stage transformational energy technologies that require proof of concept. Technologies that achieve substantial technical advancement under ARPA-E support may still face significant technical and commercial challenges upon completion of an award's funding period, and thus are at risk of being stranded in their development path once ARPA-E funding ends. Experience across ARPA-E’s diverse energy portfolios, and input from a wide range of investors and industry stakeholders, indicate that pre-commercial scaling projects are critical to establish practical performance and cost parameters. These pre-commercial scaling projects aim to 1) translate the performance achieved at bench scale to commercially scalable versions of the technology, 2) integrate the technology with broader systems, 3) provide extended performance data, and 4) validate the manufacturability and reliability of new energy technologies. Successful scaling projects should enable industry stakeholders to justify the substantial commitments of financial resources, personnel, manufacturing facilities, and materials necessary to subsequently deploy the technologies at a commercial scale. SCALEUP Ready seeks to scale the most promising technologies previously funded by ARPA-E. The possibility of ARPA-E-funded technologies becoming stranded along their development pathways leaves substantial intellectual property developed with American taxpayer dollars vulnerable to adoption by foreign competitors, who capture it for continued development and economic benefit overseas. This harms national competitiveness, as U.S. industries often fall behind on the development, scaling, and manufacturing of technologies necessary to compete in rapidly evolving global energy markets. Thus, projects selected for SCALEUP Ready will meet ARPA-E’s statutory goals by “accelerating transformational technological advances in areas that industry by itself is not likely to undertake because of technical and financial uncertainty."

Apply for funding for a research grant in any area within the remit of the Biotechnology and Biological Sciences Research Council (BBSRC). You must be based at a UK research organisation eligible for BBSRC funding. There is no limit on the value of the grant, the value specified within the summary page is an example.

This Notice of Funding Opportunity (NOFO) solicits applications to develop shared-use research facilities or research-supporting facilities that enable collaborative research and benefit broad research communities at large. The NOFO supports two existing construction programs: the Biomedical Research Facilities (BRF) program and the HIV/AIDS Research Facilities (HRF) program.The BRF program supports the construction or modernization of biomedical research facilities that advance basic, translational, clinical, or behavioral science research in all areas. Intended facilities include shared research spaces, core facilities, biorepositories, or other shared-use resource facilities that serve a broad scientific community with a significant, long-term impact on biomedical research.The HRF program funds the development of HIV/AIDS research or research-supporting resources that the empowered research activities must align with the NIH Office of AIDS Research (OAR) priorities, as outlined at OAR HIV/AIDS Research Priorities, including research focusing on the long-term health consequences of HIV infection.NIH encourages applications from institutions across all geographic regions of the country, including Institutions of Emerging Excellence (IEE) in biomedical research, to strengthen the nation"s research capacity.

Apply for funding for a research grant in any area within the remit of the Biotechnology and Biological Sciences Research Council (BBSRC). You must be based at a UK research organisation eligible for BBSRC funding. There is no limit on the value of the grant, the value specified within the summary page is an example.

This Notice of Funding Opportunity (NOFO) supports transdisciplinary research teams seeking to develop mechanistic, biologically grounded explanations of how neural circuits and their cellular building blocks give rise to central nervous system (CNS) function. Teams must integrate expertise spanning molecular and cellular through systems neuroscience, with strong collaboration between experimental and computational investigators, to bridge cells, circuits, and behavior in a unified framework that yields mechanistic insight.Applications must explicitly connect three core elements: (1) characterization of circuit components (e.g., cell types and/or connectivity); (2) measurement of dynamic circuit activity, incorporating in vivo CNS recordings at cellular and sub-second temporal resolution; and (3) analyses of a tractable behavior or functional output.To address this significant challenge in neuroscience, proposed studies are expected to leverage innovative conceptual or theoretical frameworks, predictive models, and/or cutting-edge approaches that unify these three levels of analysis and bridge experimental and computational components.Recipients are expected to participate in BRAIN consortia activities to identify standards of practice towards multi-level integration.

The purpose of this NOFO is to enhance the capability of NCATS CTSA Program KL2 scholars and recipients of re-entry supplements supported by the CTSA Program to conduct research as they complete the transition to fully independent academic translational scientists. These R03 grants will support different clinical and translational science research projects, including pilot and feasibility studies; secondary data analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. Research proposed in the R03 application may or may not include patient-oriented research. The R03 is, therefore, intended to support research projects that can be carried out in a short period of time with limited resources and that provide preliminary data to support submission of a subsequent R01, or equivalent, application.

The purpose of this Notice of Funding Opportunity (NOFO) is to leverage NICHD clinical research Network infrastructure relevant to infants, children, women, pregnant and lactating women, and persons with disabilities to conduct innovative, multisite, investigator-initiated clinical trials and observational studies. This NOFO will utilize a bi-phasic (UG3/UH3), milestone-driven mechanism consisting of a start-up phase (UG3) and a full enrollment and clinical trial implementation phase (UH3). Applications submitted in response to this NOFO must address specific aims and milestones for both the UG3 and UH3 phases. A UG3 project (phase I) that meets its milestones will be administratively considered by NICHD and prioritized for transition to the UH3 award (phase II). This NOFO provides an opportunity to leverage NICHD clinical research Network infrastructure as a platform for investigator-initiated innovative hypotheses by any investigator in the extramural community. Applications must be submitted as investigator-initiated, multi-Project Director/Principal Investigator (PD/PI) grant applications in conjunction with the respective NICHD-supported Network Data Coordinating Center (DCC), or equivalent as determined by the NICHD.

Under this FY26 grant agreement, academic partners will establish the National Center for Narrative Intelligence (NCNI) by executing RDT&E tasks across the following four pillars: workforce development, applied research infrastructure, collaborative networks, and strategic analysis for DoW leadership.

The National Science Foundation (NSF) and the National Institutes of Health (NIH) are interested in proposals that will propel our understanding of the biomedical research enterprise by drawing from the scientific expertise of the science of science policy research community. NSF promotes the progress of science by maintaining the general health of research and education across all fields of science and engineering. The Social, Behavioral and Economic Sciences (SBE) Directorate within NSF supports basic research on people and society. The SBE sciences focus on human behavior and social organizations; how social, economic, political, cultural and environmental forces affect the lives of people from birth to old age; and how people in turn shape those forces. SBE's Science of Science: Discovery, Communication and Impact Program (SoS:DCI) supports research designed to advance the scientific basis of science and innovation policy. The NIH is the U.S. federal agency charged with supporting biomedical research in the U.S. The National Institute of General Medical Sciences (NIGMS) within the NIH supports basic biomedical research that increases understanding of biological processes and lays the foundation for advances in disease diagnosis, treatment and prevention.  Both NSF and NIH believe that there are opportunities and needs for building and supporting research projects with a focus on the scientific research enterprise. The two agencies also recognize that when programmatic goals are compatible, coordinated management and funding of a research program can have a positive synergistic effect on the level and scope of research and can leverage the investments of both agencies.  Therefore, NIGMS and SBE are partnering to enable collaboration in research between the SoS:DCI program and NIGMS. This partnership will result in a portfolio of high-quality research to provide scientific analysis of important aspects of the biomedical research enterprise and efforts to foster a diverse, innovative, productive and efficient scientific workforce, from which future scientific leaders will emerge.   Prospective investigators are strongly encouraged to discuss their proposals with the program officers before submission to determine project relevance to the priorities of both SBE and NIGMS. Specific questions pertaining to this solicitation can also be directed to the SBE and NIGMS program officers.

The DWFP Program’s mission is to protect deployed military personnel from arthropod vectors of medically relevant disease pathogens, including (but not limited to) arthropod disease vectors of tick-borne pathogens and mosquito-borne arboviruses, as well as nuisance biting arthropods and emerging arthropod threats such as the New World Screwworm fly. The DWFP Program seeks to fund original and innovative research that supports the Advanced Technology Development of new insecticides, or improved formulations of existing insecticides for vector control, new technology or enhanced modalities of personal protection from biting arthropods, or improved efficacy and sustainability of equipment for application of pesticides.

This Notice of Funding Opportunity (NOFO) announces the restructured Shared Instrumentation Grant (SIG) Program that consolidates three existing shared-use instrumentation programs, i.e., the Shared Instrumentation Grant program, the High-End Instrumentation Grant program, and the Basic Instrumentation Grant program. The NOFO invites applications from groups of NIH-supported investigators to purchase or upgrade a single state-of-the-art commercially available instrument or an integrated instrumentation system. The instruments purchased through the SIG Program are required to be optimally shared among the users to ensure efficient and cost-effective research operations, enable rigorous and reproducible measurements, and encourage collaborative research and benefit broad research communities at large. The minimum award is $300,000. There is no cap on the total cost of the instrument; however, the maximum award is $5,000,000. Cost sharing is required for premium instruments or special use instruments.

The FAA hereby announces its continuing interest in receiving applications for aviation research grants and cooperative agreements to pursue the long-term growth and short-term technical needs of civil aviation, under this funding opportunity. Eligibility of applicants for the award of an aviation research grant varies depending on the nature of the proposer's organization, as well as the character of the research being proposed. In general, colleges, universities, and other non- profit research institutions under Section 501(c)(3) of Title 26 of United States Code, are eligible to apply for an aviation research grant.   The FAA Aviation Research Grants Program encourages and supports innovative, advanced research of potential benefit to the long-term growth of civil aviation and commercial space transportation. The pursuit of basic and applied research in scientific and engineering disciplines that have the potential to further knowledge and understanding on a broad front of emerging technologies is crucial to the realization of this goal. The intent is to encourage applied research and development to enhance technology assimilation, transfer, and development in the FAA. The FAA Aviation Research Grants Program does not require the immediate application to Research and Development (R&D) programs, although this may occur in some cases. The FAA encourages the submission of proposals that embrace the entire spectrum of physical, chemical, biological, medical, psychological, mathematical, and engineering sciences.   The following list illustrates topics of interest to those who may consider applying for a grant under this funding opportunity:   1.      Capacity and Air Traffic Control Technology 2.      Communications, Navigation, and Surveillance 3.      Aviation Weather 4.      Airports 5.      Aircraft Safety Technology 6.      Human Factors and Aviation Medicine 7.      Systems Science/Operations Research   For more information, please carefully review FAA Notice of Funding Opportunity 20-01, and any supporting attachments.

The People and Research Scheme offers grants for activities that help people understand and champion the historic environment through, engagement, skills, training, education and heritage project-based posts. It also offers grants for research activities related to the historic environment sector including scientific and technical conservation, surveys and investigations, publication, archiving, toolkits and guidance. https://historicengland.org.uk/advice/grants/what-we-fund/people-activities/ https://historicengland.org.uk/advice/grants/what-we-fund/research-activities/

The FY23 -FY28 Broad Agency Announcement for Extramural Biomedical Research and Development - HT9425-23-S-SOC1.

SC hereby announces its continuing interest in receiving applications for support of work in the following program areas:  ·        Advanced Scientific Computing Research ·        Basic Energy Sciences ·        Biological and Environmental Research ·        Fusion Energy Sciences ·        High Energy and Nuclear Physics ·        Isotope R&D and Production.  On September 3, 1992, DOE published in the Federal Register the Office of Energy Research Financial Assistance Program (now called the Office of Science Financial Assistance Program), 10 C.F.R. part 605, as a Final Rule, which contained a solicitation for this program. Information about submitting applications, eligibility, limitations, evaluation and selection processes and other policies and procedures are specified in 10 C.F.R. part 605. This NOFO is our annual open solicitation that covers all research areas in SC and is open throughout the fiscal year (FY). Any research within SC’s congressionally authorized mission may be proposed under this NOFO. This NOFO will remain open until September 30, 2027, 11:59 PM Eastern Time, or until it is succeeded by another issuance, whichever occurs first.

The purpose of this notice of funding opportunity (NOFO) is to  support multidisciplinary consortia of structural biologists, microbiologists, and associated experts to solve complex biological structures related to the prevention, treatment, and cure of HIV and other infectious diseases. Centers are expected to facilitate new collaborations, leverage shared resources, offer services and resources to the research community, and train the next generation of scientists engaged in structural biology of infectious diseases.

The goal of this NOFO is to fund veterinary diagnostic laboratories in the Vet-LIRN network for grants associated with projects and equipment. Specific objectives include: 1. Supporting the development, adaptation, or verification/validation of new methods associated with animal food issues or antimicrobial resistance. 2. Short-term surveillance or monitoring efforts aligned with the CVM mission. 3. Supporting equipment for testing or developing tests associated with animal food-related issues or antimicrobial resistance, including those for emerging technologies. 4. Developing projects related to antimicrobial stewardship, in alignment with CVM's key initiatives in this area. 5. Contributing as part of Vet-LIRN's AMR monitoring program, including sequencing isolates. 6. Supporting work associated with One Health, including emerging diseases such as COVID-19, when funding is available.

A. STATEMENT OF OBJECTIVES This Funding Opportunity Announcement (FOA) is to award multiple cooperative agreements to accredited United States (U.S.) two- and four-year colleges and universities (Institutions of Higher Education (IHEs)) to receive and administer scholarship and fellowship funding—provided through the University Nuclear Leadership Program (UNLP) and as administered by the Department of Energy, Office of Nuclear Energy (DOE-NE)—on behalf of selected students attending these U.S. IHEs. The selection of students to receive scholarships and fellowships through the program will occur via a separate DOE-NE process. A.1 BACKGROUND AND OBJECTIVES UNLP works to attract qualified nuclear science and engineering students (NS&E) to nuclear energy professions by providing undergraduate level scholarships and graduate level fellowships. The scholarships and fellowships are focused on two-, four-year, and graduate programs in science and engineering disciplines related to nuclear energy such as nuclear engineering, mechanical engineering, electrical engineering, chemistry, health physics, nuclear materials science, radiochemistry, applied nuclear physics, nuclear policy, radiation protection technology, nuclear power technology, nuclear maintenance technology, nuclear engineering technology, computer science, cybersecurity, nuclear safety, nuclear operations, mechanical and electrical maintenance, and radiation protection. NE’s mission is to advance nuclear energy science and technology to meet U.S. energy, environmental, and economic needs. NE has identified the following goals to address challenges in the nuclear energy sector, help realize the potential of advanced technology, and leverage the unique role of the government in spurring innovation: • Keep existing U.S. nuclear reactors operating • Deploy new nuclear reactors • Secure and sustain our nuclear fuel cycle • Expand international nuclear energy cooperation Collectively, all NE-sponsored activities support the Department’s priorities to combat the climate crisis, create clean energy jobs with the free and fair chance to join a union and bargain collectively, and promote equity and environmental justice by delivering innovative clean energy technologies for nuclear energy systems. UNLP supports NE’s Nuclear Energy University Program (NEUP), which enables outstanding, cutting-edge, and innovative research at U.S. IHEs through the following: • Integrating research and development (R&D) at U.S. IHEs, national laboratories, and industry to revitalize nuclear education and support NE’s Programs • Attracting the brightest students to the nuclear professions and supporting the nation’s intellectual capital in science and engineering disciplines • Improving U.S. IHE’s infrastructure for conducting R&D and educating students • Facilitating knowledge transfer to the next generation of workers Educating undergraduate and graduate students in NS&E will: • Support the ongoing need for personnel who can develop and maintain the nation’s nuclear power technology • Enhance the R&D capabilities of U.S. IHEs • Fulfill national demand for highly trained scientists and engineers to work in NS&E areas

The purpose of this Funding Opportunity (NOFO) is to solicit grant applications to support research on the discovery and development of interventions to prevent and/or treat substance use disorders (SUDs) and overdose, including medications and medical devices to treat co-morbid SUDs. This includes preclinical and clinical research studies that will have high impact and quickly yield the necessary results to advance candidate interventions closer to regulatory approval or clinical adoption. This NOFO will utilize the UG3/UH3 activity code.

Apply for funding to work with overseas researchers in the Unites States (US). Submit a collaborative research grant application within the remit of AHRC and US National Science Foundation, Social, Behavioural and Economic Sciences Directorate (NSF-SBE). You must be based at a UK research organisation eligible for AHRC funding. There is no limit on the value of the grant, the value specified within the summary page is an example.

The National Institute of Environmental Health Sciences (NIEHS) is announcing the continuation of the Superfund Hazardous Substance Research and Training Program, referred to as Superfund Research Program (SRP) Centers. SRP Center grants will support problem-based, solution-oriented research Centers that consist of multiple, integrated projects representing both the biomedical and environmental science and engineering disciplines; as well as cores tasked with administrative (which includes Center leadership, data management, and training); translational research and engagement; and research support functions. The scope of the SRP Centers is taken directly from the Superfund Amendments and Reauthorization Act of 1986, which limits competition for this program to accredited institutes of higher education.Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.

PLEASE FIND THE NOFO IN THE 'DOCUMENTS' SECTION OF THIS POST This opportunity has been updated as of May 11, 2026 Program Overview: EDA has authority to provide grants to meet the full range of communities’ and regions’ economic development needs from planning and technical assistance to construction of infrastructure. These grants are made through a series of Notices of Funding Opportunity (NOFOs) that can be found on EDA’s website at https://www.eda.gov/funding/funding-opportunities and are designed to support the economic development activities most useful to a community based on its needs and circumstances. EDA funds community or regionally generated ideas and assists communities to advance to the next level of economic development. This NOFO sets out EDA’s application submission and review procedures for two of EDA’s core economic development programs authorized under the Public Works and Economic Development Act of 1965, as amended (42 U.S.C. § 3121 et seq.) (PWEDA): (1) Public Works and Economic Development Facilities (Public Works) and (2) Economic Adjustment Assistance (EAA). EDA supports bottom-up strategies that build on regional assets to spur economic growth and resiliency. EDA encourages its grantees throughout the country to develop initiatives that present new ideas and creative approaches to advance economic prosperity in distressed communities. Through this NOFO EDA intends to advance general economic development in accordance with EDA’s investment priorities, which can be found on EDA's website here: Investment Priorities | U.S. Economic Development Administration

The USAFA invests in an active research program for three main reasons. First and foremost, research significantly enhances the cadet learning experience. Our research is done by, for and with cadets who work alongside fellow cadets and faculty mentors. Research provides cadets with rich independent learning opportunities as they tackle ill-defined problems and are challenged to apply their knowledge and abilities. Second, our research program provides opportunities essential for faculty development. Research broadens and deepens the experience base of the faculty. This infuses current, relevant, state-of-the-art and cutting-edge applications and examples into the curriculum. This also helps our faculty remain current in their respective fields. Third, at USAFA we strive to conduct research to enhance the ability of the Air Force to perform its mission. There are ongoing research projects spanning topics as diverse as super hypersonics, cyber security, spatial disorientation, athletic performance and homeland defense. This BAA offers a vehicle for research to be performed to satisfy these three objectives, while also meeting research needs of industry counterparts/serve a public purpose. USAFA’s partnerships with non-Government firms enables development in the public arena, stimulating the studies in the greater technical community. All awards issued against this BAA must serve to benefit the objectives identified above.

Through this Disaster NOFO, EDA will award investments in regions experiencing severe economic distress or other economic harm resulting from hurricanes, wildfires, tornadoes, floods, and other natural disasters occurring in calendar years 2023 and 2024. EDA’s goal under this NOFO is to assist communities recovering from a disaster by realizing opportunities to recover and change the economic trajectory of the community for the better. In other words, EDA funding seeks to help communities recover and set them on a path to exceed their previous pre-disaster baseline. EDA seeks projects that are responsive to community needs post-disaster by engaging all aspects of the community, with special focus on private industry partners. This Disaster NOFO provides funding through three pathways: Readiness Path – Standalone non-construction projects designed to increase a community’s readiness to apply for or implement disaster recovery funding from private and public sources including, but not limited to, future EDA NOFOs and the Implementation or Industry Transformation Paths under this NOFO. Projects will fund strategy development, capacity building, and/or predevelopment costs necessary for future recovery projects. Implementation Path – Standalone construction or non-construction projects designed to address the economic challenges faced by a community recovering from a natural disaster and improve economic trajectories beyond pre-disaster economic conditions. Industry Transformation Path – Led by a coalition of regional stakeholders, a portfolio of large-scale, multicomponent construction and non-construction projects designed to fundamentally transform the economic trajectory of a region through the development or acceleration of an industry.

The Air Force Office of Scientific Research manages the basic research investment for the Department of the Air Force. Conferences and workshops constitute key forums for research and technology interchange. We provide partial support for conferences and workshops as defined in the DoW Joint Travel Regulations in special areas of science that bring experts together to discuss recent research or educational findings, or to expose other researchers or advanced graduate students to new research and educational techniques in our areas of research interest. Our research interests are described in the most recent version of our general Broad Agency Announcement titled, “Research Interests of the Air Force Office of Scientific Research” posted on Grants.gov. We can only consider funding requests from U.S. institutions of higher education (IHE) or nonprofit organizations as described in 2 CFR 200.1, including foreign public entities and foreign organizations operated primarily for scientific, educational, service, charitable, or similar purposes in the public interest. We do not award grants to organizations with a for-profit organization type. Our support for a workshop or conference is not an endorsement of any organization.

Responding to the needs of the scientific community to bolster a vibrant and sustainable research workforce, the Division of Kidney, Urologic, and Hematologic Diseases (KUH) at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) has incorporated additional flexibilities for institutional training programs serving the mission interests of non-malignant kidney, urologic, and hematologic diseases, encompassing both adult and pediatric conditions. The purpose of this notice of funding opportunity is to invite applications for Institutional Network Awards (U2C-TL1) to recruit, train, and retain the next generation of researchers and provide them with the coordinated support, resources, and networks they need to succeed and lead. To maximize integration and promote a highly connected trainee community, institutions are invited to submit a single, unified U2C-TL1 application. Representation across all kidney, urologic, and hematologic disciplines is not expected or required. If feasible, applications may include multiple departments within and across institutions. It is expected that each U2C-TL1 award will actively participate in the Kidney, Urology and Hematology Research-Training Network (KUHR-TN), a nationwide coalition of individual U2C-TL1 awards.

Subject to the availability of funds, awards made under this NOFO will help communities and regions devise and implement long-term economic recovery strategies through a variety of non-construction and construction projects, as appropriate, to address economic challenges in areas where a Presidential declaration of a major disaster was issued under the Robert T. Stafford Disaster Relief and Emergency Assistance Act (42 U.S.C. § 5121 et seq.) (Stafford Act) “as a result of Hurricanes Ian and Fiona, and of wildfires, flooding, and other natural disasters occurring in calendar years 2021 and 2022….” EDA is excited to announce the launch of its new grants management platform: the  Economic Development Grants Experience (EDGE).  EDGE was developed to streamline the application and grants management process by implementing a  single platform  with increased transparency, improved user experience, higher data quality, and more efficiency throughout the entire grant lifecycle.    Starting April 6, 2023, applications will no longer be accepted on Grants.gov , and will ONLY be accepted through EDGE ( sfgrants.eda.gov ) . To apply for the FY 2023 Disaster Supplemental NOFO, please access the portal here . More information on how to apply is provided in the full NOFO. 

This cooperative agreement is intended to enhance the capacity and capabilities of state human and animal food testing laboratories in support of an integrated food safety system (IFSS). This is achieved through prioritized sample testing and food defense preparedness in the areas of microbiology, chemistry, and radiochemistry, as well as method development and capacity/capability development projects that support and expand food safety and food defense testing.

The purpose of this Funding Opportunity Announcement (FOA) is to solicit applications for inclusion as Animal and Veterinary Innovation Centers, which are intended to form long-term partnerships to address priority areas for FDA's Center for Veterinary Medicine (CVM). This includes CVM developing cooperative agreement(s) with academic research institutions (public and private) to:  1. Drive research that supports the development of interventions to prevent, control, or eliminate Highly Pathogenic Avian Influenza (HPAI) virus in animals, or interventions that reduce the circulation of the virus in the ecosystem. Work may also include other emerging zoonotic disease threats or One Health issues in future years.  2. Drive research that supports the development of intentional genomic alternations in animals and the advancement of regulatory science in this field, with a focus on intentional genomic alternations that support agricultural resilience, food security, animal health, or public health.  3. Drive research that supports the development of products for minor species, minor uses in major species (dogs, cats, horses, cattle, pigs, chickens, and turkeys) and other unmet veterinary medical needs in major species that create a significant animal or public health burden.

The goal of this Notice of Funding Opportunity (NOFO) is to provide funding support for the pre-clinical and early stage clinical (Phase I) development of novel small-molecule and biologic drug candidates that prevent Alzheimer's disease (AD), slow its progression, or treat its cognitive and behavioral symptoms. Participants in this program will receive funding for therapy development activities such as medicinal chemistry; pharmacokinetics (PK); Absorption, Distribution, Metabolism, Excretion, Toxicology (ADMET); efficacy in animal models; development of biomarkers for target engagement; formulation development; chemical synthesis under Good Manufacturing Practices (GMP); Investigational New Drug (IND) enabling studies; and initial Phase I clinical testing. Applications not responsive to this NOFO include research on basic mechanisms of disease or mechanisms of drug action; development ofrisk, diagnostic, prognostic, predictive, and preventionbiomarkers, devices, non-pharmacological interventions (e.g., exercise, diet, cognitive training), repurposed drugs and combination therapies; discovery activities such as high-throughput screening and hit optimization; and stand-alone clinical trials.

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs. To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on: Courses for Skills Development

NLM wishes to accelerate access to, and availability of, secure, complete datasets and computational models that can serve as the basis for transformative biomedical discoveries. Innovative at-scale computational approaches that increase the speed and scope of curation processes are needed for data mining and knowledge discovery from growing quantities of biomedical data being produced from ongoing data science advances.

The Fishing Safety Research Grant Program established by The Coast Guard Authorization Act of 2010 (P.L. 111-281), as amended by the Howard Coble Coast Guard and Maritime Transportation Act of 2014 (P.L. 113-281), is intended to provide funding to individuals in academia, members of non-profit organizations and businesses involved in fishing and maritime matters, and other persons with expertise in commercial fishing safety. The funding will be used to support research on improving the occupational safety of workers in the commercial fishing industry. This includes: improving vessel design; developing and improving emergency and survival equipment; enhancing vessel monitoring systems; improving communication devices, de-icing technology, and severe weather detection. In order to support and administer the grant program, the Coast Guard and NIOSH signed a Memorandum of Understanding on May 17, 2018. While the Coast Guard, along with the Occupational Safety and Health Administration (OSHA), provides regulatory oversight for safety and health matters within the commercial fishing industry, NIOSH is an agency operating under the Centers for Disease Control and Prevention (CDC) with the mission of generating new knowledge in occupational safety and health and transferring that knowledge into practice to prevent worker injury, illness and death. NIOSH conducts and funds scientific research, develops methods to prevent occupational hazards, develops guidance and authoritative recommendations, translates scientific knowledge into products and services, disseminates information, identifies factors underlying work-related disease and injury and responds to requests for workplace health hazard evaluations. NIOSH has an extensive history of conducting research to understand and to reduce hazards in the commercial fishing industry. This research has largely been conducted in close collaboration with crews, industry and the US Coast Guard. To learn more about NIOSH’s work in commercial fishing safety and health, visit https://www.cdc.gov/niosh/topics/fishing/default.html. Research objectives supported by NIOSH include, but are not limited to, the following: identification and investigation of the relationships between hazardous working conditions and associated occupational injuries and fatalities; development of more sensitive means of evaluating hazards at work sites; development of methods for measuring early markers of injuries and fatalities; development of new protective equipment and engineering control technology to reduce work-related injuries and fatalities; development of work practices that reduce the risks of occupational hazards; and evaluation of the technical feasibility or application of a new or improved occupational safety procedure, method, technique, or system, including assessment of economic and other factors that influence their diffusion and successful adoption in workplaces.

The goal of the training grant program is to enhance the quality and availability of safety training for United States commercial fishermen. Availability includes the frequency, geographic considerations, channels or partners of dissemination, culturally and/or educational appropriate training material, and other characteristics of a successful training program. As a result, the Coast Guard and NIOSH invite applications to support the development and implementation of training and education programs that: develop and deliver training which addresses the needs of commercial fishermen in the United States provide qualified marine safety instructors, or otherwise accepted by the National Maritime Center instructors and faculty to conduct the training evaluate the effectiveness and impact of the training program on reducing injuries among fishermen coordinate with existing training programs and partnerships with industry fishermen, and agencies conform to 46 U.S.C. § 4502 (i) Safety Standards for commercial fishing safety training In order to support and administer the grant program, the Coast Guard and NIOSH signed a Memorandum of Understanding on May 17, 2018. While the Coast Guard, along with the Occupational Safety and Health Administration (OSHA), provides regulatory oversight for safety and health matters within the commercial fishing industry, NIOSH is an agency operating under the Centers for Disease Control and Prevention (CDC) with the mission of generating new knowledge in occupational safety and health and transferring that knowledge into practice to prevent worker injury, illness and death. NIOSH conducts and funds scientific research, develops methods to prevent occupational hazards, develops guidance and authoritative recommendations, translates scientific knowledge into products and services, disseminates information, identifies factors underlying work-related disease and injury and responds to requests for workplace health hazard evaluations.

The  Chemical Oceanography  Program supports research into the chemistry of the oceans and the role of the oceans in global geochemical cycles. Areas of interest include chemical composition, speciation, and transformation; chemical exchanges between the oceans and other components of the Earth system; internal cycling in oceans, seas, and estuaries; and the use of measured chemical distributions as indicators of physical, biological, and geological processes.

This Notice of Funding Opportunity (NOFO) invites applications that propose to use mouse models to conduct rigorous preclinical testing of drugs or drug combinations currently used for other conditions, as well as investigational drugs at various stages of clinical development, predicted to be efficacious in AD/ADRD. This initiative will also support preclinical testing of repurposable or investigational drug candidates in combination with non-pharmacologic interventions leading to robust translational outcomes. The central goal is to establish robust proof of concept that will enable rational drug repurposing and combination therapy development for the treatment and prevention of AD/ADRD.

This funding opportunity announcement (FOA) encourages the development and validation of animal models and human/animal tissue ex vivo systems that recapitulate the phenotypic and physiologic characteristics of a defined neurological or neuromuscular disorder. The goal of this FOA is to promote a significant improvement in the translational relevance of animal models or ex vivo systems that will be utilized to facilitate future development of neurotherapeutics. Ideally, models proposed for this FOA would have the potential to provide feasible and meaningful assessments of efficacy following therapeutic intervention that would be applicable in both preclinical and clinical settings. This FOA is part of a suite of Innovation Grants to Nurture Initial Translational Efforts (IGNITE) Program focused on enabling the exploratory and early stages of drug discovery.

This funding opportunity announcement (FOA) encourages research grant applications to develop in vitro and/or ex vivo assays and conduct iterative screening efforts to identify and characterize potential therapeutic agents for neurological or neuromuscular disorders. This FOA is part of a suite of Innovation Grants to Nurture Initial Translational Efforts (IGNITE) to advance projects to the point where they can meet the entry criteria for the Blueprint Neurotherapeutics Network (BPN) or other translational programs.

The CTSA Collaborative and Innovative Acceleration Award (CCIA) aims to accelerate the pace of translational research by supporting the collaborative development, dissemination, and sustainable implementation of innovative solutions across the CTSA Program Consortium and beyond. This Notice of Funding Opportunity (NOFO) invites investigator-initiated applications to develop, demonstrate, and disseminate innovative new approaches, technologies, resources, or models that increase the impact of research across diseases, transform the field of translational science, and bring more treatments for all people more quickly.

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to stimulate efforts to translate scientific discoveries and engineering developments into methods or tools that address problems in basic research to understand disease, or in applied research to assess risk, detect, prevent, diagnose, treat, and/or manage disease. The rationale is to deliver new capabilities to meet evolving requirements for technologies and methods relevant to the advance of research and delivery of care in pre-clinical, clinical and non-clinical settings, domestic or foreign, for conditions and diseases within the missions of participating institutes.

The overall goal of this program is to accelerate scientific discovery, improve research efficiency, and enhance the translation of research findings into improved health outcomes. Centers funded under this program will also foster multidisciplinary collaboration, support workforce development across career stages, and promote training in emerging areas such as data science, artificial intelligence, and implementation research. The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) requests applications for the NIAMS P30 Centers Program to support integrated research Centers within its mission areas of skin biology and diseases; bone, muscle, and orthopaedic research; and rheumatic diseases. The NIAMS P30 Centers Program supports Centers that provide coordinated research infrastructure, shared resources, and methodological expertise to advance basic, translational, and clinical research. These Centers are expected to integrate state-of-the-art research resources with capabilities that support clinical and translational research, including the development, testing, and dissemination of novel analytical methods, study designs, outcome measures, and data-driven approaches.

This Notice of Funding Opportunity (NOFO) will support, through the cooperative agreement mechanism, investigator-initiated observational studies or biomarker validation studies that require prospective collection of data/biospecimens or continued analysis of data/biospecimens.

The National Institute on Deafness and Other Communication Disorders (NIDCD), with the National Institute of Biomedical Imaging and Bioengineering (NIBIB) aims to support the development and/or adaptation of transformative in vivo high-resolution/high specificity imaging of the human olfactory system. Currently, there are limited non-invasive/minimally invasive technologies available for imaging the living human peripheral and central olfactory system with high spatial and temporal resolution. Imaging the olfactory system in the laboratory and in the clinic is essential to understanding underlying biological mechanisms as well as the etiology of an olfactory disorder. Such imaging has proven challenging due to the olfactory system"s unique anatomical and functional characteristics such as restricted accessibility, multiple cell types, and low signal resolution. Addressing these challenges requires multimodal approaches including leveraging existing advanced tools and technologies and developing new tools tailored for the olfactory system. Recent advances in minimally invasive and non-invasive imaging technologies, such as cell specific biomarkers, fluorescence imaging, specialized endoscopes, optical and acoustic imaging, molecular imaging, and hemodynamic and diffusion imaging have the potential to transform our ability to image and investigate the peripheral and central olfactory system in the living human with superior temporal and spatial resolution and eventually improve diagnostic accuracy of olfactory disorders. Applications must leverage advanced non-invasive/minimally invasive imaging technologies to visualize peripheral (e.g., olfactory- and non-olfactory epithelium) and central olfactory (e.g., olfactory bulb) targets at a level previously unattainable. In addition, projects should engage multidisciplinary teams combining expertise in olfaction, biomedical imaging, biochemistry, bioengineering, and biophysics, as appropriate.

The National Institute for Occupational Safety and Health (NIOSH), Centers for Disease Control and Prevention (CDC), invites grant applications for Training Project Grants (TPGs) that are focused on occupational safety and health training. NIOSH is mandated to provide an adequate supply of qualified personnel to carry out the purposes of the Occupational Safety and Health Act, and the TPGs are one of the principal means for meeting this mandate. The majority of TPGs are in academic institutions that provide high quality undergraduate, graduate, and post graduate academic training in a variety of occupational safety and health (OSH) and allied disciplines. NIOSH also funds a limited number of non-academic TPGs to provide specialized training for target audiences and build or strengthen the Nation's OSH workforce capacity.

The purpose of this Notice of Funding Opportunity (NOFO) is to invite research grant applications (R01) for the development and use of current and emerging molecular imaging methods to gain fundamental insights into cancer inflammation in vivo. The motivation for this initiative is that much of current imaging research into the role of inflammation in cancer is largely based on in vitro and ex vivo methods with limited utilization of imaging approaches that could lead to significant new insights relevant to dynamic cancer and inflammation interactions. Utilization of molecular imaging probes in pre-clinical and clinical investigations for precise temporal resolution at the molecular and cellular level are valuable approaches for identification and characterization of in vivo inflammatory cellular physiology in cancers and of molecular changes in response to treatment. This FOA encourages applications that focus on developing integrated imaging approaches to interrogate the role of inflammation in cancer through strong cross-field collaboration between cancer basic science researchers and imaging scientists. These collaborations are expected to advance science and understanding of cancer inflammation interactions.

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) is soliciting applications for the establishment of the Management and Data Coordination Unit (MDCU), one of the two scientific components of the Pancreatic Cancer Detection Consortium (PCDC). The PCDC will continue to address one of the four research priorities identified in the National Cancer Institute's 2014 Scientific Framework for Pancreatic Ductal Adenocarcinoma and conduct research on early detection of pancreatic ductal adenocarcinoma (PDAC) and characterization of its precursor lesions to identify those patients who are at high risk of progression to cancer. The PCDC-MDCU will provide support towards collaborative efforts such as study design, protocol development, statistical analysis, coordination and data management. Other PCDC-MDCU activities include: coordination and support towards biorepository building; and organizational and logistics support for PCDC activities.

The Division of Mathematical Sciences (DMS) in the Directorate for Mathematical and Physical Sciences (MPS) at the National Science Foundation (NSF) and the National Institute of General Medical Sciences (NIGMS) at the National Institutes of Health (NIH) plan to support fundamental research in mathematics and statistics necessary to answer questions in the biological and biomedical sciences. Both agencies recognize the need to promote research at the interface between mathematical and life sciences. This program is designed to encourage new collaborations, as well as to support innovative activities by existing teams. The joint DMS/NIGMS initiative offers two submission tracks: Track 1 - for projects with a total budget of up to $600,000 for an award duration of 3 years, and Track 2 - for projects with a total budget of up to $1,200,000 for an award duration of 3-4 years.

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) invites applications for support of investigator-initiated studies addressing mechanisms by which bariatric surgery impacts cancer risk, and seeks to draw in talented scientists who study bariatric surgery to investigate its effects on cancer, rather than shorter-term outcomes such as weight loss and diabetes.

This Notice of Funding Opportunity (NOFO) invites applications for innovative research on the factors that cause human behaviors and the oral-systemic health impacts of those behaviors to enhance health, lengthen life, and reduce illness and disability among people with chronic conditions. Causal hypotheses may include biological, biopsychosocial, congenital, environmental, interpersonal, neurological, psychological, and comorbidity factors that individually, sequentially, or in combination trigger human behaviors and oral-systemic health outcomes, with impacts that may be direct or traceably distal. Applications that propose projects to develop or refine causal hypotheses also are encouraged.

Through this Notice of Funding Opportunity (NOFO), NCI solicits applications for the Research Units (RUs), one of the two scientific components of the Pancreatic Cancer Detection Consortium (PCDC), to conduct research on early detection of pancreatic ductal adenocarcinoma (PDAC) and characterization of its precursor lesions to identify patients who are at high risk of progression to cancer. The PCDC will continue to address one of the four research priorities identified in the NCI's 2014 Scientific Framework for Pancreatic Ductal Adenocarcinoma (PDAC). The PCDC will support research for the development and testing of new molecular and imaging biomarkers for detecting PDAC early and for identifying patients at high risk of PDAC (because of genetic factors, family history and/or the presence of precursor lesions) who could be candidates for early intervention. The PCDC-RUs will consist of multi-disciplinary teams and will undertake studies to: identify and test biomarkers measurable in bodily fluids for early detection of PDAC and/or its precursor lesions; develop molecular- and/or imaging-based markers of pancreatic cysts and determine which lesions are likely to progress to cancer; develop molecular- and/or imaging-based approaches for screening populations at high risk of PDAC; use machine learning and computational approaches towards biomarker discovery and/or validation; and conduct biomarker validation studies. The PCDC-RUs will also collect longitudinal biospecimens for building a biorepository. Each PCDC-RU is expected to participate in collaborative activities with other PCDC-RUs and share ideas, biospecimens, and data within the Consortium.

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) seeks research project (R01) grant applications describing projects that integrate imaging and fluid-based tumor monitoring (liquid biopsy) assays during cancer therapy in patients to determine the optimal use of those modalities in the characterization of therapy response and/or emergence of resistance.

The National Cancer Institute's (NCI) Metastasis Research Network (MetNet) is a collection of U54 Research Centers that support using systems-level approaches to understand pressing questions in metastasis. The overall goal of the MetNet is to advance our understanding of metastasis as a whole body, systems-level problem to develop a comprehensive and cohesive picture of the processes involved. Through this Notice of Funding Opportunity (NOFO), the NCI invites applications for MetNet Research Projects. These Research Projects should be defined as discrete entities that use systems-level approaches to address gaps and opportunities in metastasis research to integrate into the MetNet and complement ongoing research across the Network.

This Funding Opportunity Announcement (FOA) is intended to provide an avenue for basic scientists, clinicians and clinical scientists to jointly initiate and conduct translational research projects which translate basic research findings into clinical tools for better human health. The scope of this FOA includes a range of activities to encourage translation of basic research findings which will impact the diagnosis, treatment and prevention of communication disorders. Connection to the clinical condition must be clearly established and the outcomes of the grant must have practical clinical impact.

This Notice of Funding Opportunity Announcement (NOFO) invites R25 applications to support the development and implementation of research education programs for recent baccalaureates from all backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences. It is essential to expand and broaden the skilled Alzheimers Disease (AD) and Alzheimers Disease and Related Dementias (ADRD) research workforce and provide exposure to AD/ADRD research to individuals early in their careers. The proposed research education programs will support intensive research experiences in the AD/ADRD field with the goal of preparing recent baccalaureates to transition into strong, research-focused advanced degree programs or competitive private sector research careers in AD-related disciplines.

The purpose of this Notice of Funding Opportunity (NOFO) is to encourage UG3/UH3 phased cooperative agreement research applications to plan and implement behavioral and social intervention clinical trials. Studies appropriate for this announcement include clinical trials to develop and test behavior change interventions related to dental, oral, or craniofacial conditions. Awards made under this FOA will initially support a milestone-driven planning phase (UG3) for up to 2 years, with possible transition to a clinical trial implementation phase (UH3) of up to five years. Only UG3 projects that have met the scientific milestones and feasibility requirements may transition to the UH3 phase. The UG3/UH3 application must be submitted as a single application, following the instructions described in this FOA. The UG3 phase will permit both scientific and operational planning activities. Scientific planning activities include small-scale data collection to assess the feasibility and/or acceptability of a planned behavioral or social intervention and associated study procedures (e.g., acceptability of study content or mode of delivery; feasibility of proposed data collection procedures; preliminary testing of intervention training and fidelity monitoring procedures). Operational planning activities include, at a minimum, development of: the final clinical protocol; the intervention manual or equivalent; the data management system and other tools for data and quality management, safety and operational oversight plans; recruitment and retention strategies; and other essential documents. The UH3 phase will support the conduct of investigator-initiated intervention research at all stages, from early mechanistic research and intervention development (e.g., Stages 0/ I) through implementation and cost-effectiveness research (Stages IV/V).

The Division of Mathematical Sciences (DMS) in the Directorate for Mathematical and Physical Sciences (MPS) at the National Science Foundation (NSF) and the National Institute of General Medical Sciences (NIGMS) at the National Institutes of Health (NIH) plan to support fundamental research in mathematics and statistics necessary to answer questions in the biological and biomedical sciences. Both agencies recognize the need to promote research at the interface between mathematical and life sciences. This program is designed to encourage new collaborations, as well as to support innovative activities by existing teams. The joint DMS/NIGMS initiative offers two submission tracks: Track 1 - for projects with a total budget of up to $600,000 for an award duration of 3 years, and Track 2 - for projects with a total budget of up to $1,200,000 for an award duration of 3-4 years.

This Notice of Funding Opportunity (NOFO) encourages collaborations between the life and physical sciences that: 1) apply a multidisciplinary bioengineering approach to the solution of a biomedical problem; and 2) integrate, optimize, validate, translate or otherwise accelerate the adoption of promising tools, methods, and techniques for a specific research or clinical problem in basic, translational, or clinical science and practice. An application may propose design-directed, developmental, discovery-driven, or hypothesis-driven research and is appropriate for small teams applying an integrative approach to increase our understanding of and solve problems in biological, clinical, or translational science. This NOFO will support clinical trials that test functionality or validate performance in the chosen setting. This NOFO is not intended to support conventional clinical trials that lack translation as the primary motivation. Applications that propose phase III clinical trials in any area of research are not sought by and will not be supported through this NOFO. This NOFO does not support commercial production.

The purpose of this initiative is to support the development of innovative research centers to foster nursing-led programs that promote community-partnered research to address persistent health challenges. Center applications developed in response to this RFA should propose strategies to strengthen the research infrastructure by establishing or expanding centralized research resources in School or College of Nursing (SON/CON), developing and enhancing nurse-led interdisciplinary teams, and building expertise in community-partnered research through conducting pilot research that applies NINR's research lenses. Center strategies should be informed by NINRs mission and should meaningfully engage the community throughout all activities.

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to stimulate efforts to translate scientific discoveries and engineering developments into methods or tools that address problems in basic research to understand disease, or in applied research to assess risk, detect, prevent, diagnose, treat, and/or manage disease. The rationale is to deliver new capabilities to meet evolving requirements for technologies and methods relevant to the advance of research and delivery of care in pre-clinical, clinical and non-clinical settings, domestic or foreign, for conditions and diseases within the missions of participating institutes.