Grants for individuals

This NOFO is modified. The webinar link was changed and the ECD website address changed. The U.S. Department of Health and Human Services (HHS), Administration for Children and Families (ACF), seeks applications for the Preschool Development Grant Birth through Five (PDG B-5) SMART Grant: Strategic Measurement, Analytics, and Results using Technology. This funding opportunity will support states and territories to make targeted, one-year investments in statewide early care and education (ECE) technology and analytic data infrastructure that advance PDG B-5 purposes, including strengthening coordination across the mixed-delivery system, improving program quality and access, supporting informed family choice, and using data to better understand and address the needs of children from birth through age five. Applicants will propose a focused, feasible investment that strengthens the state's ability to generate actionable information for decision-making and produces a measurable result by the end of the project period.

The Office of Population Affairs (OPA) announces the anticipated availability of funds for Fiscal Year (FY) 2027 grants under the authority of Title X of the Public Health Service Act, Section 1001 (42 U.S.C. §300).This notice solicits applications for projects to provide Title X services throughout the 50 United States, District of Columbia, Guam, the Commonwealth of Puerto Rico, the Northern Mariana Islands, the U.S. Virgin Islands, American Samoa, the U.S. Outlaying Islands (Midway, Wake, et al.), the Republic of the Marshall Islands, the Federated State of Micronesia, and the Republic of Palau (hereafter, States). OPA intends to make available approximately up to $257 million for up to 90 grant awards for a period of up to five (5) years. The actual amount available will not be determined until enactment of the FY 2027 federal budget.OPA"s Title X Family Planning Program funds "voluntary family planning projects [that] offer a broad range of acceptable and effective family planning methods and services (including natural family planning methods, infertility services, and services for adolescents)." (Title X of the Public Health Service Act, 42 U.S.C. 300 et seq., available at https://opa.hhs.gov/sites/default/files/2020-07/title-x-statute-attachment-a_0.pdf). The Title X Program is implemented through competitively awarded grants to a diverse network of public and private nonprofit entities. The program helps millions of low-income and uninsured Americans develop health literacy and access family planning and related health services, empowering individuals and families to make informed decisions and navigate chronic health conditions and pregnancy with confidence. By offering counseling and education to improve individuals" optimal health outcomes, Title X promotes the level of health literacy necessary to support informed consent across the reproductive lifespan. For example, endometriosis often goes undiagnosed for years because symptoms such as severe menstrual pain or irregular bleeding are frequently normalized or minimized. Body literacy counseling helps patients recognize that these experiences are not "normal" features of womanhood, but potential indicators of an underlying condition, prompting earlier discussion with providers, timely diagnosis, appropriate treatment, and improved long-term reproductive and overall health outcomes.Likewise, foundational knowledge of reproductive physiology enables patients and couples to recognize early signs of dysfunction, seek timely evaluation, and participate meaningfully in care decisions. Persistent gaps in reproductive knowledge highlight the need for such education. For example, a survey conducted for OPA in 2020 found that only 50% of women and 38% of men know that a woman"s ovaries do not keep producing new eggs until menopause (https://opa.hhs.gov/sites/default/files/2021-01/fertility-knowledge-survey-findings-exec-summary-2020.pdf). By supporting body literacy education alongside evidence-based evaluation and treatment of chronic disease, Title X services can help patients move beyond symptom-focused care toward informed, preventive, and restorative approaches to reproductive health.These efforts align with HHS"s focus on addressing the root causes of chronic illnesses by targeting conditions that affect reproductive health and fertility. By promoting strategies that support education and counseling on reproductive health goals, reduce chronic disease, and assist individuals seeking to achieve healthy pregnancies, the Title X Program strengthens American families, individuals, and communities.This notice solicits applications from public and private nonprofit entities to establish and operate voluntary Title X projects. These projects include a broad range of effective and acceptable services, including pregnancy testing and counseling, basic infertility services, sexually transmitted infection (STI) services (such as HIV prevention education, counseling, testing, and referral), health literacy, reproductive goals counseling to increase optimal health outcomes, and other preconception health services. Title X services also help address and provide referrals for health conditions that affect fertility, including endometriosis, polycystic ovary syndrome (PCOS), and uterine fibroids in women, as well as low sperm count, low sperm motility, low testosterone, and erectile dysfunction in men. OPA seeks a broad competition for Title X grant awards and are interested in innovative strategies to address chronic disease; reduce overmedicalization by strengthening approaches focused on underlying behavioral and lifestyle factors of health and evidence-based practices such as fertility-awareness based methods; promote health and body literacy; advance reproductive goals counseling for all clients; and support family formation.All activities funded under this announcement must be in compliance with the requirements of the Title X statute, legislative mandates, and regulations. Copies of the Title X statute, regulations, and legislative mandates may be downloaded from the OPA website at https://opa.hhs.gov/grant-programs/title- x-service-grants/title-x-statutes-regulations-and-legislative-mandates.

The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications to characterize genomic variation to assess the impact of individual variants on genome function. This will be accomplished by systematically perturbing variants or elements using one or more high-throughput methods; collecting data on the effects of variants in DNA, RNA, or protein-coding elements on molecular, cellular, or organismal phenotypes; and developing robust, reproducible, and portable data processing pipelines. Centers funded through this initiative will become a part of the Impact of Genomic Variation on Function (IGVF) Consortium. As consortium members, centers will work together to ensure all consortium resources are accessible to a wide variety of potential users. Centers are also expected to collaborate with other consortium components to coordinate assays, variants, and cell types, and to develop shared analysis strategies to meet consortium goals.

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes: Increased understanding of European policy makers, research community, biotech companies, and relevant security practitioners of the threat of bioterrorism and of synthetic biology, including a thorough lawful analysis of what needs to be monitored in this context, what needs to be regulated and how; Awareness raised within the related scientific community how research in synthetic biology can be used for malicious purposes. Scope: The rising threat of bioterrorism is driven by recent scientific advancements, notably by growing accessibility of synthetic biology, genetic engineering, related commercial services and public databases, which in turn enhance their obtainability to non-state actors and individuals with malicious intentions. The proliferation of do-it-yourself biohacking and community laboratories, including gene editing and sequencing technology, dropping costs of equipment and increased simplicity of use may inadvertently facilitate knowledge and skills dissemination about biological threats and open new pathways for bioterrorism. Challenges in detection,…

This is a notice of funding opportunity (NOFO) for the NIJ FY 2026 Research on Gender Dysphoria and Violent Crime. This opportunity will support foundational research on gender dysphoria, its treatment, and the perpetration of violence and violent behavior. Available empirical evidence regarding this topic is limited, particularly in regard to underlying causal mechanisms. To address these gaps, NIJ is interested in retrospective, secondary data analyses that explore gender dysphoria, its treatment, and the perpetration of violence and violent behavior. Examples include, but are not limited to: • Prevalence rates of violent crime and behavior for this population, to include demographic information and crime type characteristics. • Post-conviction analyses, to include analyses based on individuals who have been incarcerated. • Analyses examining the relationship between violence and gender dysphoria diagnosis and/or treatment. • Research on the victim/offender overlap or other contextual factors to interpret trends. • Impact of comorbidities (e.g., substance use disorders and/or mental health disorders) on the relationship between violence and gender dysphoria diagnosis and/or treatment.

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes: Housing-led approaches [1] aligned with the NEB are made available to stakeholders involved in tackling homelessness [1] . Robust evidence on NEB-aligned housing-led approaches tackling homelessness (including people temporarily hosted by acquaintances and family) to inform the development and/or update of policies and services for prevention and early intervention in the context of the green transition [1] in neighbourhoods [1] . Scope: Social and affordable housing is being advanced in the EU, including through the Affordable Housing Initiative [5] . Despite efforts, current policies for the green transition are failing to adequately address the housing crisis. Homelessness remains a structural challenge across Europe, with negative impacts on both individuals experiencing it (e.g. physical and mental health, social and economic conditions) and neighbourhood communities [1] (e.g. pressure on public services, erosion of social fabric [1] , etc.). Research and innovation gaps in tackling homelessness range from data collection (i.e. the variety of approaches to defining,…

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes: Evidence of the structural social infrastructure [1] and services needed to address homelessness [1] at neighbourhood [1] level is made available to stakeholders involved in tackling homelessness. Improved availability and accessibility of key social infrastructure and services for homeless groups in the targeted neighbourhoods. Scope: Based on 2024 data, over 1.2 million people are estimated to experience homelessness in Europe [4] , with a significant proportion (45%) of surveyed homeless individuals finding themselves in a situation of chronic homelessness for over two years [5] . While housing-led approaches [1] are crucial to tackle homelessness, addressing the structural and multidimensional causes of homelessness also requires systemic interventions focusing on social infrastructure and services in neighbourhoods. Social infrastructure and services include the physical places as well as public and community [1] sector facilities and services that support and enable access to healthcare, employment, education, community integration, and other social services. They must be…

The purpose of this NOFO is to further the IHS mission and goals related to providing quality health care to the AI/AN community through outreach and education. Our focus is on promoting awareness, visibility, training, technical assistance, and education in the following components:Health education and outreach.Rural Health Transformation review and outreach and education on the Indian Health Care Improvement Act.Substance abuse and suicide prevention.Domestic violence prevention.Special diabetes program for American Indians.Tribal budget formulation activities.Tribal youth health advisory activities.

The National Institute for Occupational Safety and Health (NIOSH) supports research projects that address: (1) physical and mental health conditions related to the September 11, 2001, terrorist attacks; (2) diagnosing conditions for which there has been diagnostic uncertainty; and (3) treating conditions for which there has been treatment uncertainty. Conditions may have emerged since the treatment program began or since the WTC Health Program was established. This announcement solicits meritorious and scientifically rigorous applications that will: 1) improve diagnosis and treatment activities of the WTC Health Program; 2) expand knowledge about health effects related to the September 11, 2001, terrorist attacks; 3) answer critical questions about WTC-related physical and mental health conditions; and 4) apply lessons learned to improve response to future disasters. Potential projects may include, but are not limited to: (a) Screening research to evaluate current methods or facilitate the development of new or improved methods to detect disorders or health conditions; (b) Diagnostic research to evaluate current methods or facilitate the development of new or improved methods to identify diseases, disorders, or conditions; (c) Treatment research to evaluate or identify improved treatment interventions or methods, or to promote development of new or novel approaches; (d) Prevention research to identify or evaluate methods and interventions that prevent or mitigate the development or recurrence of diseases or disorders; (e) Quality of life research to identify, develop, or evaluate methods or interventions that improve comfort and quality of life for individuals with chronic illness or multimorbidity; (f) Omics research to improve methods for predicting disorders by identifying and understanding relationships between genes and illness (e.g., phenotypes and biomarkers), including how genetic factors influence disease development or response to treatment; (g) Epidemiologic or clinical research to identify patterns, causes, and control of adverse health effects among the 9/11-exposed population; (h) Health services research to examine access to care, cost of care, and outcomes associated with care delivery; (i) Implementation research to evaluate how research findings are disseminated, adopted, implemented, sustained, and scaled in real-world settings; and (j) Epidemiologic research to investigate emerging conditions where preliminary data suggest, but do not confirm, a causal relationship between 9/11 exposure and the condition. Examples can be found at https://www.cdc.gov/wtc/received.html.

This is a special Notice of Funding Opportunity Announcement (NOFO) sponsored by the Air Force Office of Scientific Research (AFOSR), which will hereafter generally be referred to as “we”, “us”, “our”, or “AFOSR.” The Fiscal Year 2027 Air Force Young Investigator Research Program (YIP) intends to support individual early career scientists and engineers who have received their Ph.D. or equivalent degrees by 01 April 2019 or later showing exceptional ability and promise for conducting basic research. The program objective is to foster creative basic research in science and engineering; enhance early career development of outstanding young investigators; and increase opportunities for the young investigators to recognize the Air Force and Space Force mission and related challenges in science and engineering. Individual awards are made to U.S. institutions of higher education, industrial laboratories, for- profit, or non-profit research organizations where the principal investigator (PI) is employed on a full-time basis and holds a regular, non-contractor position. A YIP PI must be a U.S. citizen, national, or permanent resident. Researchers working at a Federally Funded Research and Development Center (FFRDC), or a Department of War (DoW) Laboratory are not eligible for this competition. YIP awards are funded up to $150,000 per year for three years, for a total of $450,000. No single year may exceed $150,000. Please review the remainder of this announcement for additional information. Under this competition, an anticipated thirty-seven (37) traditionally funded YIPs and three (3) YIPs funded in partnership with the Laboratory for Physical Sciences (LPS) in the Quantum Information Sciences research discipline may be awarded. There may be potential for an additional 37 YIPs funded from other AFOSR research funding. All actions are based on the availability of funds. Proposers are encouraged to confer with the designated AFOSR Program Officer(s) prior to submitting a full proposal. We will evaluate proposals using an internal review panel. AFOSR reserves the right to select and fund all, some, or none of the proposals from any of the topics below. AFOSR provides no funding for direct reimbursement of proposal development costs. Technical and budget proposals (or any other material) submitted in response to this NOFO will not be returned. It is the policy of AFOSR to treat all white papers and proposals submitted under this NOFO as sensitive competitive information and to disclose their contents only for the purposes of evaluation. White papers briefly summarizing the proposed institution’s ideas are required . Submit white papers to our whitepaper portal, which is linked below. The topic points of contact (POCs) will coordinate to provide feedback on the white papers. The proposals will need to include a data management plan, outlining how samples and data collected in the program will be stored and managed. This includes but is not restricted to issues such as standards for data and metadata collection, content and format, data archiving, database management, and data sharing within, outside the awardee and beyond the lifetime of the grant. This precondition is modeled on the National Science Foundation Data Management Plan requirement (e.g., https://www.nsf.gov/eng/data-management-plans). IMPORTANT NOTE: Applicants should be alert for any amendments that may modify the announcement. Amendments to the original Notice of Funding Opportunity (NOFO) will be posted to the Grants.gov Webpage: https://www.grants.gov/. IMPORTANT DATES: Pre-proposal inquiries and questions, regarding white papers and the submission of those white papers, must be received in writing by electronic mail to the address(es) of this NOFO not later than 17 September 2026 at 11:59 PM Eastern Time to be considered. The Government will respond to any pre-proposal inquiries or questions via public posting, or individual responses, no later than COB on 24 September 2026. Whitepapers must be received by 09 October 2026 at 11:59 PM Eastern Time via submission to https://afosr.gov1.qualtrics.com/jfe/form/SV_eKuTqm9qezoDYep to be considered. White paper evaluation is meant to initially assess the capability of a proposed effort. White papers must be no more than five (5) pages in length. References and CV/bios will not count against the page limit. Please review this announcement in its entirety prior to submitting a white paper. The government will respond to the white paper determination before COB on 06 November 2026 . Proposals must be received electronically through Grants.gov by 04 December 2026 at 11:59 PM Eastern Time to be considered. We anticipate that we will notify proposers of selection or non-selection for award no later than 26 April 2027 . We anticipate awards to be made by 01 May 2027 , barring delays. 

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes: Improved protection of minors, including by more reliable age assessments and by minimising the use of intrusive age assessment methods; Improved adaptation, preparedness and cooperation of authorities in the fight against human trafficking; Expanded European-based knowledge on reliability, accuracy and effectiveness of age assessment methods. Scope: Many unaccompanied children and young persons arriving at the external EU borders and seeking asylum, lack official documents showing their identity and age. Age assessment methods are important as they contribute to the determination of, for example, where an individual will be initially housed and what services, supports, and legal processes they will receive to ensure protection and, if applicable, child protection. In other cases, minors are victim of trafficking of human beings (THB) criminal activities, either across the EU external borders, or within the EU borders. In other cases again, age assessment methods are necessary for law enforcement investigations on protecting children, forensic investigation, and/or the…

Expected Outcome: The action is expected to mature and demonstrate (TRL 6-8) innovative technologies in one of the key areas set out under the scope of the topic: developing and advancing the technology readiness of innovative individual components and/or integrated systems that perform the key functions of fusion power plants (FPPs), in line with the key area targeted; testing the innovative components and/or systems developed in close-to-real-life conditions, demonstrating the ability to deliver fusion-grade components and/or systems; providing a credible business case, clarifying the potential and perspectives for commercialisation of the components and/or systems developed, and showing the benefits for the competitiveness and growth of EU companies from the fusion field. Scope: to ensure a successful transition to commercially viable fusion power plants, the Commission is establishing a co-programmed public-private partnership, maximising the convergence of publicly funded action and privately led initiatives. This European Partnership on Fusion Energy is being established with the support of a coordination and support action funded under the Euratom programme. It will…

The World Trade Center (WTC) Health Program supports exploratory and developmental research projects (R21) that address issues related to diagnostic or treatment uncertainty among individuals receiving monitoring and/or treatment under Subtitle C of the James Zadroga 9/11 Health and Compensation Act of 2010, as amended. This R21 Notice of Funding Opportunity (NOFO) is intended to encourage exploratory/developmental research by supporting the early and conceptual stages of project development to assess the feasibility of new areas of investigation with the potential to improve treatment effectiveness and diagnostic practices. These studies may lead to breakthroughs in a particular area or to the development of new interventions, techniques, agents, methodologies, models, or approaches with potential clinical impact. They are expected to break new ground or extend prior discoveries in new directions or applications. Applicants are expected to propose research for which there is likely to be minimal or no preliminary data.

This Notice of Funding Opportunity (NOFO) invites applications for Diabetes Research Centers (DRCs) that are designed to support and enhance the national research effort in diabetes, its complications, and related endocrine and metabolic diseases. The purpose of this Centers program is to bring together basic and clinical investigators to enhance communication, multidisciplinary collaboration, and effectiveness of ongoing research in Diabetes Research Center topic areas. By providing shared access to specialized technical resources (research cores) and supporting a Pilot and Feasibility Program (P&F), DRCs are intended to create an environment that provides the capability for accomplishments greater than those that would be possible by individual research project grant support alone. New Center programs that bring in diverse perspectives, propose unique scientific themes, or provide innovative resources are encouraged. Emphasis will be placed on Center programs that propose enhanced synergies with other NIDDK-funded programs as well as providing a rich mentoring environment for future diabetes researchers.

Supports landowners and tenants within the National Forest or close to the boundary to create woodland, enhance habitats and deliver environmental, community and economic benefits through tree planting and forest creation projects. The grant uses standard-cost items with rates linked to nationally available tree-planting and agri-environment grants.

The objective of the program is to provide a basis for advancing science-based fisheries management for Atlantic bluefin tuna. Such advancement will depend upon improvements in understanding of the fisheries, total abundance, and biology of bluefin tuna, especially regarding the effects of mixing and movement between the eastern and western Atlantic populations. Contracting Parties to the International Commission for the Conservation of Atlantic Tunas (ICCAT), of which the US is one, and other partners have embarked upon a multi-year research program on bluefin tuna as a step toward improving ICCAT's science-based management of Bluefin fisheries. Research sponsored under this funding opportunity represents a contribution to this partnership. Proposals that demonstrate collaborations with the ICCAT Atlantic Bluefin Tuna Research Program and other ICCAT partners are strongly encouraged.

The Human Networks and Data Science program (HNDS) supports research that enhances understanding of human behavior by leveraging data and network science research across a broad range of topics. HNDS research will identify ways in which dynamic, distributed, or heterogeneous data can provide novel answers to fundamental questions about individual or group behavior. HNDS is especially interested in proposals that provide data-rich insights about human networks to support improved health, prosperity, and security. HNDS has two tracks: (1) Human Networks and Data Science – Infrastructure (HNDS-I). Infrastructure proposals will address the development of data resources and relevant analytic techniques that support fundamental Social, Behavioral and Economic (SBE) research. Successful infrastructure proposals will construct, within the financial resources provided by the award, databases or relevant analytic techniques and produce a finished product that will enable previously impossible data-intensive research in the social sciences. The databases or techniques should have significant impacts, either across multiple fields or within broad disciplinary areas, by making possible new types of data-intensive research in the SBE sciences. (2) Human Networks and Data Science – Core Research (HNDS-R). Core research proposals will advance theory in a core SBE discipline by the application of data and network science methods. This includes the leveraging of large data sets with diverse spatio-temporal scales of measurement and linked qualitative and quantitative approaches, as well as multi-scale, multi-level network data and techniques of network analysis. Supported projects are expected to yield results that will enhance, expand, and transform theory and methods, and that generate novel understandings of human behavior – particularly understandings that can lead to significant societal benefits or opportunities. HNDS-R encourages core research proposals that make innovative use of NSF-supported data networks, databases, centers and other forms of scientific infrastructure including those developed by HNDS-I (formerly RIDIR) projects .

The purpose of this Notice of Funding Opportunity (NOFO) is to advance the development of novel informatics and data science approaches that can help individuals understand and improve their health through actionable insights. NLM seeks applications that further the science of personal health informatics by providing meaningful and actionable insights to individuals through innovative personal health data collection, integration, analysis, and personalized risk assessments and interpretation. Applications seeking to advance the understanding of how informatics tools, systems, and platforms can best present the results, interpretation, and limitations of personalized assessments for the benefit of individuals are encouraged. Applications should include end user engaged approaches and real-world evaluation to inform the design of generalizable, reusable, and scalable personal health informatics tools, systems, and platforms for the benefit of individuals in understanding and improving their health.

This grant program provides competitive grants to non-Federal researchers working to benefit U.S. fishermen and fisheries, including aquaculture, through the development of improved fishing practices and innovative gear technologies. The Magnuson-Stevens Fishery Conservation and Management Act, as amended (MSA), 16 U.S.C. 1865, requires that NOAA’s conservation and management measures minimize bycatch to the extent practicable and established the Bycatch Reduction Engineering Program (BREP) to support the development of technological devices and other conservation engineering changes to minimize bycatch and reduce post-release mortality of non-target species in our nation’s fisheries. Bycatch reduction is a priority for the National Marine Fisheries Service (NMFS), as outlined in the NMFS National Bycatch Reduction Strategy (https://www.fisheries.noaa.gov/national/bycatch/national-bycatchreduction-strategy). Fisheries bycatch can contribute to overfishing, population declines for threatened and endangered species, and can result in commercial fishery closures. This Program seeks to support the development and testing of fishing gears and approaches that can be applied in commercial and recreational fisheries to reduce bycatch and post-release mortality and address the MSA requirements to minimize bycatch and habitat impacts.  

The purpose of this Funding Opportunity Announcement (FOA) is to support high priority research at the intersection of HIV and substance use. This FOA invites innovative research projects with the potential to open new areas of HIV/AIDS research and/or lead to new avenues for prevention, treatment and cure of HIV among people who use drugs (PWUD). Applications submitted under this FOA are required to have a detailed research plan, preliminary data, and a clear description of the nexus with substance use. This FOA is open to both individual researchers and research teams and includes all areas of research from basic science to clinical and implementation research. All studies must focus on NIH HIV/AIDS Research Priorities: NOT-OD-20-018: UPDATE: NIH HIV/AIDS Research Priorities and Guidelines for Determining HIV/AIDS Funding.

INL announces a funding opportunity for qualified individuals to provide expert advisory and mentoring support to specialized anti-organized crime and corruption departments in Bosnia and Herzegovina, covering both the Federation of Bosnia and Herzegovina and Republika Srpska. Criminal networks in Bosnia and Herzegovina have documented links to Western Hemisphere cartels that launder drug proceeds and shield corrupt officials, directly threatening U.S. security and economic interests. Bosnia and Herzegovina sits on the Balkan Route, a key corridor for narcotics, weapons, and migrant smuggling.The selected expert or experts will strengthen prosecutorial capacity within the Federation of Bosnia and Herzegovina's Specialized Department for Corruption and Organized Crime, known as POSKOK, and its Republika Srpska counterpart by delivering structured advisory sessions, participating in legal reform working groups, and providing case-based mentoring to prosecutors, judges, and investigators. Key objectives include strengthening prosecutorial methodology aligned with the Federation of Bosnia and Herzegovina 2014 Law on the Suppression of Corruption and Organized Crime, and developing a structured case prioritization framework to help departments manage complex, high-level caseloads and identify cases with a U.S. nexus.

Society’s most important advances have stemmed from those willing to think differently about what might be possible. ARIA is an R&D funding agency built to unlock scientific and technological breakthroughs that benefit everyone. Created by an Act of Parliament, and sponsored by the Department for Science, Innovation, and Technology, ARIA funds breakthrough R&D in under explored areas to catalyse new paths to prosperity for the UK and the world.

The NIH Cardiovascular Repository for Type 1 Diabetes (CaRe-T1D) was created to improve research on type 1 diabetes (T1D) and cardiovascular disease (CVD). Cardiovascular complications remain the top cause of death among people with T1D and greatly shorten lifespan. The mechanisms underlying atherosclerosis, cardiomyopathy, endothelial dysfunction, and cardiac autonomic neuropathy in T1D remain poorly understood. While managing traditional risk factors—such as high blood glucose, high blood pressure, and elevated cholesterol lower cardiovascular risk, a significant residual risk remains even with optimal control. In addition to atherosclerosis, both diastolic and systolic diabetic cardiomyopathy play a major role in morbidity and mortality among these patients. Currently, no therapies are specifically approved to prevent or treat these common and severe cardiovascular issues in T1D. The purpose of this NOFO is to promote collaborative and interdisciplinary research aimed at enhancing the understanding of the development of CVD in individuals with T1D and the differences with CVD in T1D by continuing the efforts of the CaRe-T1D consortium.This NOFO is associated with the Special Diabetes Program (https://www.niddk.nih.gov/about-niddk/research-areas/diabetes/type-1-diabetes-special-statutory-funding-program/about-special-diabetes-program) which funds research on the prevention, treatment, and cure of type 1 diabetes and its complications, including unique, innovative, and collaborative research consortia and clinical trials networks.

The Cladding Safety Scheme (CSS) will meet the cost of addressing life safety fire risks associated with cladding on residential buildings over 11m in height (11-18m in London).

This NOFO is modified. Changes are made to Step 1: Review the Opportunity. The Office of Refugee Resettlement (ORR) provides temporary housing and care for children who arrive in the United States alone. These are children who are under 18 years old, don't have legal permission to be in the U.S., and don't have a parent or legal guardian in the U.S. who can take care of them. ORR runs the Home Study and Post-Release Services Program to help these children. Before placing a child with a sponsor, ORR carefully checks potential homes to make sure they're safe and appropriate. After placement, ORR provides ongoing support to help children and their sponsors succeed. This support helps children adjust to living with their sponsor, connect with their community, stay safe and healthy, and navigate the immigration court process. The goal is to make sure children are placed in safe homes and have the support they need to thrive while their immigration cases move forward.

Grants for projects that repair, conserve and care for historic places including buildings, structures, monuments, landscapes and areas.

FindBusinessSupport.gov.scot gives an overview of grants, loans, funding, advice and other support available to businesses in Scotland, offered by over 100 Scottish public sector organisations, conveniently in one place. Information is available for businesses of all sizes and sectors, from start-ups and sole traders to large enterprises and includes support for social enterprises.

Commissioned Rehabilitative Services General Grant Scheme for support for people with shared protected characteristics or shared experiences or to promote rehabilitation and desistance to support the aims of Her Majesty’s Prison and Probation Service (HMPPS) to protect the public and reduce reoffending. This includes the aims to improve people’s engagement in, and experience of, probation and other rehabilitative activities; to support an individual’s rehabilitation and desistance journey; and to improve HMPPS’ knowledge of which activities work to support people and to encourage rehabilitation and desistance.

The People and Research Scheme offers grants for activities that help people understand and champion the historic environment through, engagement, skills, training, education and heritage project-based posts. It also offers grants for research activities related to the historic environment sector including scientific and technical conservation, surveys and investigations, publication, archiving, toolkits and guidance. https://historicengland.org.uk/advice/grants/what-we-fund/people-activities/ https://historicengland.org.uk/advice/grants/what-we-fund/research-activities/

England Woodland Creation Offer (EWCO) supports the establishment of new woodlands and is administered by the Forestry Commission. The ‘Find a grant’ tool requires a ‘closing date’ to be specified – 31 March 2030 reflects the period EWCO funding is currently confirmed until, rather than a known closure date. EWCO is funded through the Defra Trees Programme.

Improving Oversight of Federal Grantmaking VA is required to ensure compliance with all applicable statutes, regulations, and Executive Orders when evaluating and awarding grants. In accordance with Executive Order 14332, Improving Oversight of Federal Grantmaking, aside from the evaluation criteria published in this announcement, VA has discretion to remove from consideration any applicant VA deems does not clearly advance the President's or VA's priorities. VA will not fund activities that use racial preference for eligibility criteria or promote gender ideology. VA will not fund activities that promote or facilitate violations of immigration laws or are sources of waste, fraud, or abuse. VA will not tolerate activity or conduct by grant recipients that constitute acts of moral turpitude, are scandalous, or bring the recipient, the project funded by this grant, or VA into public disrepute, contempt, or ridicule. These grants support the President's priority to increase the excellence of and options for care, benefits, and services for veterans, as demonstrated in  Executive Order 14332 . Program is subject to Public Law 117-58 Build America, Buy America Act. Recipients of an award of Federal financial assistance from a program for infrastructure are hereby notified that none of the funds provided under this award may be used for a project for infrastructure unless:(1) all iron and steel used in the project are produced in the United States--this means all manufacturing processes, from the initial melting stage through the application of coatings, occurred in the United States; (2) all manufactured products used in the project are produced in the United States—this means the manufactured product was manufactured in the United States; and the cost of the components of the manufactured product that are mined, produced, or manufactured in the United States is greater than 55 percent of the total cost of all components of the manufactured product, unless another standard for determining the minimum amount of domestic content of the manufactured product has been established under applicable law or regulation; and (3) all construction materials44 are manufactured in the United States—this means that all manufacturing processes for the construction material occurred in the United States. The Buy America preference only applies to articles, materials, and supplies that are consumed in, incorporated into, or affixed to an infrastructure project. As such, it does not apply to tools, equipment, and supplies, such as temporary scaffolding, brought to the construction site and removed at or before the completion of the infrastructure project. Nor does a Buy America preference apply to equipment and furnishings, such as movable chairs, desks, and portable computer equipment, that are used at or within the finished infrastructure project, but are not an integral part of the structure or permanently affixed to the infrastructure project. Grants are available to State and Tribal Governments for construction or renovations of State/Tribal owned and operated Veterans Extended Care Facilities. The Department of Veterans Affairs participation may not exceed 65% of the total project costs. Review governing regulation before submitting an application (38 CFR Part 59). If the state is submitting a  new  grant application, it must submit a  complete  initial application (Section A of the project checklist) on Grants.gov by April 15th in order to be eligible for listing on the Priority List for the next fiscal year. Once the  complete  initial application is retrieved from Grants.gov by Program Staff, the grant applicant will receive 1) an automated notification from Grants.gov confirming receipt by the Program and 2) an email from Program Staff indicating the application's FAI number and corresponding project page in MAX.gov for submission of subsequent items. Note that Grants.gov is used only once to submit a  new  grant application. Applicants must submit  complete initial applications on Grants.gov in order to be considered. Please contact Program Staff prior to submission if you need assistance understanding the requirements pertaining to an initial grant application, or if you need general assistance. Renovation or Life Safety initial grant applications require items A.1.-A.7. in Section A of the project checklist. Grant applicants,  do not  submit items A.8.-.A.13 for Renovation of Life Safety grants. Adult Day Health Care, New Home Construction or Bed Replacement initial grant applications require all items in Section A (A.1.-A.13) of the project checklist. Required for ALL applications  A.1.A Project Scope  A.1.B Form SF424 A.1.C Form SF424D A.1.D Form SF424C A.1.E Budget Justification Worksheet (must align with SF424C budget form) A.2. Governor's designation of authorized state official and contact person A.3. Needs assessment (as outlined in VA Form 10-0388-1) A.4. State Clearinghouse Comments (E.O. 12372) single point of contact and compliance statement A.5. Schematics A.6. Signed Initial Application Certification VA Form 10-0388-1  A.7. Safety citation/letter (Only Life Safety projects need to submit this). Required for Adult Day Health Care, Bed Replacement or New Construction - Items A1-A6 and the below items A.8. Space program analysis (NHC use Form 10-0388-3, ADHC use Form 10-0388-4)  A.9. Five-year capital plan for state's entire state home program A.10. Financial plan for state facility's first three years of operation A.11. Documentation that there is a reasonable basis to conclude that the facility when complete will be fully occupied A.12. Authorized state official's certification of the total number of state-operated nursing home and domiciliary beds and occupancy rate A.13. Authorized state official's certification that the number of state home beds does not exceed the requirement in 38 CFR 59.40 or justification for number of state home beds exceeding 38 CFR 59.40 based on travel distance

Responding to the needs of the scientific community to bolster a vibrant and sustainable research workforce, the Division of Kidney, Urologic, and Hematologic Diseases (KUH) at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) has incorporated additional flexibilities for institutional training programs serving the mission interests of non-malignant kidney, urologic, and hematologic diseases, encompassing both adult and pediatric conditions. The purpose of this notice of funding opportunity is to invite applications for Institutional Network Awards (U2C-TL1) to recruit, train, and retain the next generation of researchers and provide them with the coordinated support, resources, and networks they need to succeed and lead. To maximize integration and promote a highly connected trainee community, institutions are invited to submit a single, unified U2C-TL1 application. Representation across all kidney, urologic, and hematologic disciplines is not expected or required. If feasible, applications may include multiple departments within and across institutions. It is expected that each U2C-TL1 award will actively participate in the Kidney, Urology and Hematology Research-Training Network (KUHR-TN), a nationwide coalition of individual U2C-TL1 awards.

Subject to the availability of funds, awards made under this NOFO will help communities and regions devise and implement long-term economic recovery strategies through a variety of non-construction and construction projects, as appropriate, to address economic challenges in areas where a Presidential declaration of a major disaster was issued under the Robert T. Stafford Disaster Relief and Emergency Assistance Act (42 U.S.C. § 5121 et seq.) (Stafford Act) “as a result of Hurricanes Ian and Fiona, and of wildfires, flooding, and other natural disasters occurring in calendar years 2021 and 2022….” EDA is excited to announce the launch of its new grants management platform: the  Economic Development Grants Experience (EDGE).  EDGE was developed to streamline the application and grants management process by implementing a  single platform  with increased transparency, improved user experience, higher data quality, and more efficiency throughout the entire grant lifecycle.    Starting April 6, 2023, applications will no longer be accepted on Grants.gov , and will ONLY be accepted through EDGE ( sfgrants.eda.gov ) . To apply for the FY 2023 Disaster Supplemental NOFO, please access the portal here . More information on how to apply is provided in the full NOFO. 

PLEASE FIND THE NOFO IN THE 'DOCUMENTS' SECTION OF THIS POST This opportunity has been updated as of May 11, 2026 Program Overview: EDA has authority to provide grants to meet the full range of communities’ and regions’ economic development needs from planning and technical assistance to construction of infrastructure. These grants are made through a series of Notices of Funding Opportunity (NOFOs) that can be found on EDA’s website at https://www.eda.gov/funding/funding-opportunities and are designed to support the economic development activities most useful to a community based on its needs and circumstances. EDA funds community or regionally generated ideas and assists communities to advance to the next level of economic development. This NOFO sets out EDA’s application submission and review procedures for two of EDA’s core economic development programs authorized under the Public Works and Economic Development Act of 1965, as amended (42 U.S.C. § 3121 et seq.) (PWEDA): (1) Public Works and Economic Development Facilities (Public Works) and (2) Economic Adjustment Assistance (EAA). EDA supports bottom-up strategies that build on regional assets to spur economic growth and resiliency. EDA encourages its grantees throughout the country to develop initiatives that present new ideas and creative approaches to advance economic prosperity in distressed communities. Through this NOFO EDA intends to advance general economic development in accordance with EDA’s investment priorities, which can be found on EDA's website here: Investment Priorities | U.S. Economic Development Administration

The Tree Health Pilot (THP) scheme is testing different ways of slowing the spread of pests and diseases affecting trees in England. It expands on support available through the Countryside Stewardship Woodland Tree Health grant. The THP supports owners and managers of trees in woodland or trees outside woodland to deal with tree health issues. Funding from the pilot can go towards a range of measures including: felling and treating diseased or infested trees and necessary infrastructure improvements; restocking with new trees and capital items to assist this; maintenance of newly planted trees biosecurity items. he Tree Health Pilot guidance on GOV.UK sets out the aims of the pilot in detail including eligibility and application details.

Through this Disaster NOFO, EDA will award investments in regions experiencing severe economic distress or other economic harm resulting from hurricanes, wildfires, tornadoes, floods, and other natural disasters occurring in calendar years 2023 and 2024. EDA’s goal under this NOFO is to assist communities recovering from a disaster by realizing opportunities to recover and change the economic trajectory of the community for the better. In other words, EDA funding seeks to help communities recover and set them on a path to exceed their previous pre-disaster baseline. EDA seeks projects that are responsive to community needs post-disaster by engaging all aspects of the community, with special focus on private industry partners. This Disaster NOFO provides funding through three pathways: Readiness Path – Standalone non-construction projects designed to increase a community’s readiness to apply for or implement disaster recovery funding from private and public sources including, but not limited to, future EDA NOFOs and the Implementation or Industry Transformation Paths under this NOFO. Projects will fund strategy development, capacity building, and/or predevelopment costs necessary for future recovery projects. Implementation Path – Standalone construction or non-construction projects designed to address the economic challenges faced by a community recovering from a natural disaster and improve economic trajectories beyond pre-disaster economic conditions. Industry Transformation Path – Led by a coalition of regional stakeholders, a portfolio of large-scale, multicomponent construction and non-construction projects designed to fundamentally transform the economic trajectory of a region through the development or acceleration of an industry.

The Fishing Safety Research Grant Program established by The Coast Guard Authorization Act of 2010 (P.L. 111-281), as amended by the Howard Coble Coast Guard and Maritime Transportation Act of 2014 (P.L. 113-281), is intended to provide funding to individuals in academia, members of non-profit organizations and businesses involved in fishing and maritime matters, and other persons with expertise in commercial fishing safety. The funding will be used to support research on improving the occupational safety of workers in the commercial fishing industry. This includes: improving vessel design; developing and improving emergency and survival equipment; enhancing vessel monitoring systems; improving communication devices, de-icing technology, and severe weather detection. In order to support and administer the grant program, the Coast Guard and NIOSH signed a Memorandum of Understanding on May 17, 2018. While the Coast Guard, along with the Occupational Safety and Health Administration (OSHA), provides regulatory oversight for safety and health matters within the commercial fishing industry, NIOSH is an agency operating under the Centers for Disease Control and Prevention (CDC) with the mission of generating new knowledge in occupational safety and health and transferring that knowledge into practice to prevent worker injury, illness and death. NIOSH conducts and funds scientific research, develops methods to prevent occupational hazards, develops guidance and authoritative recommendations, translates scientific knowledge into products and services, disseminates information, identifies factors underlying work-related disease and injury and responds to requests for workplace health hazard evaluations. NIOSH has an extensive history of conducting research to understand and to reduce hazards in the commercial fishing industry. This research has largely been conducted in close collaboration with crews, industry and the US Coast Guard. To learn more about NIOSH’s work in commercial fishing safety and health, visit https://www.cdc.gov/niosh/topics/fishing/default.html. Research objectives supported by NIOSH include, but are not limited to, the following: identification and investigation of the relationships between hazardous working conditions and associated occupational injuries and fatalities; development of more sensitive means of evaluating hazards at work sites; development of methods for measuring early markers of injuries and fatalities; development of new protective equipment and engineering control technology to reduce work-related injuries and fatalities; development of work practices that reduce the risks of occupational hazards; and evaluation of the technical feasibility or application of a new or improved occupational safety procedure, method, technique, or system, including assessment of economic and other factors that influence their diffusion and successful adoption in workplaces.

This grant provides landlords with support towards the cost of the purchase and installation of electric vehicle chargepoints at residential properties.

The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. The purpose of this Notice of Funding Opportunity (NOFO) is to solicit Transformative Research Award applications to support individual scientists or groups of scientists proposing groundbreaking, exceptionally innovative, original, and/or unconventional research that has the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies related to Down syndrome. Applications are welcome in all topics relevant to Down syndrome-related research or its co-occurring conditions. No preliminary data are required. Projects must clearly demonstrate, based on the strength of the logic, a compelling potential to produce a major impact in research related to Down syndrome.

This Notice of Funding Opportunity Announcement (NOFO) invites R25 applications to support the development and implementation of research education programs for recent baccalaureates from all backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences. It is essential to expand and broaden the skilled Alzheimers Disease (AD) and Alzheimers Disease and Related Dementias (ADRD) research workforce and provide exposure to AD/ADRD research to individuals early in their careers. The proposed research education programs will support intensive research experiences in the AD/ADRD field with the goal of preparing recent baccalaureates to transition into strong, research-focused advanced degree programs or competitive private sector research careers in AD-related disciplines.

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this R25 program is to support educational activities that help recruit individuals with specific specialty or disciplinary backgrounds to research careers in biomedical, behavioral and clinical sciences.

The National Library of Medicine (NLM) seeks applications for research projects that drive groundbreaking innovation and advanced development in the fields of bioinformatics, translational bioinformatics, and computational biology. The primary goal of this initiative is to support the creation and implementation of cutting-edge methods, tools, and approaches that can transform the landscape of biomedical data science. This NOFO aims to address the growing need to leverage transformative technologies — such as artificial intelligence (AI), machine learning, and large-scale computational platforms — to extract actionable knowledge from vast, diverse, and complex biological datasets. By enabling more effective interpretation and integration of multi-dimensional biological and biomedical data, this research will ultimately contribute to improving individual and population health outcomes.

The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. This Notice of Funding Opportunity (NOFO) invites researchers to submit applications for support of new exploratory and developmental research projects that address critical needs for Down syndrome projects, as articulated in the INCLUDE Project objectives. For example, such projects could assess the feasibility of a novel area of investigation or a new experimental system that has the potential to enhance health-related research. Another example could include the unique and innovative use of an existing methodology to explore a new scientific area. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research.

This Notice of Funding Opportunity (NOFO) invites R25 applications to support the development and implementation of summer research education programs for high school students, undergraduates, or science teachers from all backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences. It is essential to expand and broaden the skilled Alzheimer's Disease (AD) and Alzheimers Disease Related Dementias (ADRD) research workforce and provide exposure to AD/ADRD research to individuals early in their careers. The proposed research education programs will support intensive summer research experiences in the AD/ADRD field with the goal of exposing participants to AD/ADRD research and encourage further study or participation in biomedical and behavioral research. This NOFO does not allow participants to lead an independent clinical trial, but does allow them to obtain research experience in a clinical trial led by a mentor or co-mentor.

Supporting UK screen content businesses across film, TV, animation and interactive narrative video games to enhance their international activities.

This announcement supports Executive Order 14276, Restoring America’s Seafood Competitiveness, by soliciting projects that support: workforce development for marine-related professions in marine science, aquaculture/mariculture, and maritime operations; enhancing seafood safety and management through training in seafood best practices, marketing, and fishery management; technological innovation in fishing practices; outreach and education for consumers on quality and sustainability of wild caught fish or products farmed through aquaculture/mariculture; enhanced regionally-specific management of fishery resources based on local knowledge; and strengthening the seafood supply chain through partnerships with industry, researchers, and community organizations to build relationships that increase the sustainability and competitiveness of the marine community in Alaska. Proposed projects must be conducted in Alaska. 

The Woodland Creation Planning Grant (WCPG) offers funding of up to £30,500 for the production of a UKFS-compliant woodland creation design plan. Landowners, land managers and public bodies can apply. WCPG is open for applications year-round. The ‘Find a grant’ tool requires a ‘closing date’ to be specified, however 31 March 2030 reflects the period WCPG funding is currently confirmed until, rather than a known closure date. The scheme was re-launched in autumn 2020 to enable more people to apply and help proposals move more quickly through the Environmental Impact Assessment process and future planting and establishment grant funding.

This is an Annual Program Statement, outlining our funding priorities, the strategic themes we focus on, and the procedures for submitting requests for funding. Purpose of Small Grants: The Austrian-American Partnership Fund (AAPF) is organized to fund projects advancing collaboration and dialogue and expand cooperation between Austria and the United States. AAPF accepts applications for funding for innovative projects that seek to bring American perspectives to Austria or connect Americans and Austrians in the following priority areas: • Promote understanding of U.S. global foreign policy and economic priorities and interests among Austrian publics, particularly young people, and support U.S.-Austrian initiatives that advance these priorities. • Contribute to strengthening U.S.-Austria efforts to combat shared transnational threats, such as terrorism, illegal migration, antisemitism, or drug trafficking. • Enhance understanding of the United States and U.S.-Austrian shared history and celebrate American arts, film, sports, and music, particularly among youth, including in connection with America’s 250th anniversary in 2026. • Highlight American technological and scientific innovation and economic dynamism and create opportunities for U.S.-Austria collaboration in these fields. Proposals will be considered on a rolling basis and subject to the availability of Public Diplomacy funds for Fiscal Year 2026. The selection process can take up to two - three months. ELIGIBILITY The Public Diplomacy Section encourages applications from Austria, European or, U.S.-based organizations and individuals with proven experience of executing programs. Proposals that demonstrate the long-term sustainability of the proposed project will receive priority. The following organizations are eligible to apply: • Not-for-profit organizations, including think tanks and civil society/non-governmental organizations • Public and private educational institutions • Individuals

The Wheelchair Accessible Vehicle (WAV) grant is available into financial year (FY) 2025/26 with price cap of £50,000, with grant rates up to £2,500 for an eligible vehicle. The recent price cap increase to £50,000 will bring more vehicles into scope, widening customer choice and removing barriers for disabled passengers by ensuring they can get around more easily and with peace of mind.

The Boiler Upgrade Scheme (BUS) supports the decarbonisation of homes and small and medium non-domestic buildings in England and Wales. The scheme provides upfront capital grants of up to £7,500 to encourage property owners to replace existing fossil fuel heating with more efficient, low carbon heating systems including heat pumps and biomass boilers.

The grant provides electric vehicle (EV) drivers with support towards the costs of the purchase and installation of EV chargepoints at residential properties when also installing a cross-pavement charging solution.

The grant provides electric vehicle (EV) drivers who are renters or own a flat with support towards the costs of the purchase and installation of EV charge points.

The Electric Car Grant will support the industry and drivers by reducing the prices of new, eligible EVs priced at or under £37,000.

Spruce Site Assessment can help to evaluate costs involved in felling spruce in the proactive spruce removal area and identify funding available to help with the cost.

Payments are available for farmers in England for vet visits and diagnostic testing to reduce endemic diseases, improve productivity, and raise welfare standards across herds and flocks. It is part of the wider Animal Health and Welfare Pathway. The grant provides direct payments to livestock keepers to cover the cost of these vet visits.

Skills Bursaries provide grants of up to £1,000 for people seeking to grow their expertise in community heritage work. Open to applicants at any stage of their personal or professional journey, these bursaries can be used for training, mentoring, attending workshops, or other professional development activities related to heritage and community engagement to be determined by you. Offered on a rolling basis, Skills Bursaries are designed to be accessible and responsive, helping to build confidence and capacity across the sector—particularly among those who may not have had access to such opportunities before.

Funds may be used to pay expenses associated with providing technical assistance and/or training (TAT) to: Identify and evaluate solutions to water problems relating to source, storage, treatment, or distribution; identify and evaluate solutions to waste problems relating to collection, treatment, or disposal: assist applicants, that have filed a pre-application with RUS, in the preparation of water and/or waste loan and/or grant applications; and/or provide technical assistance and/or training to water/wastewater system personnel that will improve the management, operation and maintenance of water and waste disposal facilities. Grant funds may not be used to duplicate current services, such as those performed by an association’s consultant in developing a project; fund political or lobbying activities; pay for capital assets; purchase real estate or vehicles; improve or renovate office space, or repair and maintain privately owned property; pay the costs for construction, improvement, rehabilitation, modification or operation and maintenance of water, wastewater, and solid waste disposal facilities; and pay costs incurred prior to effective date of grant.

Amendment 0008 The purpose of this amendment is to extend the due date for acceptance of White Papers. All other terms and conditions remain unchanged. -------------------------------------------------------------- Amendment 0007 The purpose of this amendment is to add Summary Topic 61-24-06 - AFFF ALTERNATIVE PROGRAM COMPATIBILITY OF FLUORINE-FREE FOAM (F3) WITH NON-ASPIRATING SPRINKLER NOZZLES to Appendix 1 in it’s entirety. All other terms and conditions remain unchanged. -------------------------------------------------------------- Amendment 0006 The purpose of this amendment is to extend the due date for acceptance of White Papers. All other terms and conditions remain unchanged. -------------------------------------------------------------- Amendment 0005 The purpose of this amendment is to provide a searchable list of Summary Topics contained in Appendix 1. Expanded descriptions of each topic can be found in the full announcement pdf. APPENDIX 1 – RESEARCH DESCRIPTION - SUMMARY TOPICS   II. Detailed information about the funding opportunity   The Naval Research Laboratory (NRL) is the Navy's corporate laboratory. NRL conducts basic and applied research for the Navy in a variety of scientific and technical disciplines. The basic research program is driven by perceptions about future requirements of the Navy. The Navy's operational effectiveness depends on its ability to keep pace with rapidly developing technologies. NRL contributes to this requirement by conducting research in the following areas, organized into NRL'S three research directorates and Naval Center for Space Technology: Systems Directorate Code 5000 Materials Science and Component Technology Directorate Code 6000 Ocean and Atmospheric Science and Technology Directorate Code 7000 Naval Center for Space Technology Code 8000 A.   SYSTEMS DIRECTORATE - CODE 5000 53-24-01 - HIGH FREQUENCY RADAR 53-24-01C - HIGH FREQUENCY RADAR (CLASSIFIED) 53-24-02 - LOW-COST WIDEBAND ANTENNA ARRAY TECHNOLOGIES 53-24-03 - ADVANCED COMPUTATIONAL ELECTROMAGNETICS 55-24-01 - INFORMATION AND DECISION SCIENCES 55-24-02 - MATHEMATICAL FOUNDATIONS OF HIGH ASSURANCE COMPUTING 55-24-03 - HIGH ASSURANCE ENGINEERING AND COMPUTING 55-24-04 - ADVANCED NAVAL NETWORK SOLUTIONS 55-24-05 - FEDERATED, DISTRIBUTED COMPUTING/NETWORK INFRASTRUCTURE 56-24-01 - OPTICAL SCIENCES R&D 57-24-01  - ELECTROMAGNETIC TECHNIQUES AND TECHNOLOGY RESEARCH AND DEVELOPMENT 57-24-02  ​ - SHIPBOARD ELECTRONIC WARFARE   B. MATERIALS SCIENCE AND COMPONENT TECHNOLOGY DIRECTORATE CODE 6000 60-24-01 - HIGH PERFORMANCE COMPUTING ON MASSIVELY PARALLEL ARCHITECTURES 61-24-01 - ELECTROCHEMICAL ENERGY STORAGE, CONVERSION AND COMMAND/CONTROL 61-24-02 - CORROSION PROCESSES, CONTROL, MITIGATION, AND TECHNOLOGY 61-24-03 - APPLICATIONS OF MOLECULAR BIOLOGY, BIOCHEMISTRY, ANALYTICAL CHEMISTRY AND ADVANCED LASER TECHNIQUES 61-24-04 - MULTIECHELON DIAGNOSTICS (MEDx) TECHNOLOGY DEVELOPMENT AND TIERED EVALUATION 63-24-01 - MATERIALS PERFORMANCE, PROCESSING, AND MODELING 67-24-01 - BASIC AND APPLIED RESEARCH IN PLASMA SCIENCE 68-24-01 - RADIATION EFFECTS RESEARCH 68-24-02 - PHOTOVOLTAICS FOR PORTABLE POWER   C.   OCEAN AND ATMOSPHERIC SCIENCE AND TECHNOLOGY DIRECTORATE CODE 7000 71-24-01 - ACOUSTIC SIMULATION AND TACTICS 72-24-01 - LOW FREQUENCY RADIO INTERFEROMETRY 72-24-02 - OPTICAL REMOTE SENSING OF THE COASTAL REGIME 72-24-03 - REMOTE SENSORS AND IMAGING SYSTEMS 72-24-04 - AIRBORNE, SHIPBOARD, AND OVERHEAD DATA ACQUISITION AND ANALYSIS 73-24-01 - OCEAN DYNAMICS AND PREDICTION OCEANOGRAPHY 73-24-02 - SEAFLOOR SCIENCES 73-24-03 - GEOSPATIAL SCIENCES AND TECHNOLOGY 75-24-01 - ATMOSPHERIC EFFECTS, ANALYSIS, AND PREDICTION 76-24-01 - RESEARCH INTO SPACE, BACKGROUNDS, IMAGING AND MODELING   D.   NAVAL CENTER FOR SPACE TECHNOLOGY CODE 8000 82-24-01 - SPACECRAFT & SPACE SYSTEMS TECHNOLOGY -------------------------------------------------------------- Amendment 0004 The purpose of this amendment is to extend the due date for acceptance of White Papers and revise Appendix 1 Summary Topics and email addresses in it’s entirety. -------------------------------------------------------------- Amendment 0003 The purpose of this amendment is to extend the due date for acceptance of White Papers. All other terms and conditions remain unchanged. ------------------------------------------------------------- Amendment 0002 The purpose of this amendment is to extend the due date for acceptance of White Papers. All other terms and conditions remain unchanged. ------------------------------------------------------------- Amendment 0001 The purpose of this amendment is to extend the due date for acceptance of White Papers. All other terms and conditions remain unchanged. -------------------------------------------------------------- The Naval Research Laboratory is interested in receiving innovative proposals that offer potential for advancement and improvement in the technical topic areas listed. This notice constitutes a Broad Agency Announcement (BAA) as contemplated in FAR 6.302(d) that provides for the competitive selection of research proposals. The Government reserves the right to select for award all, some, or none of the proposals received. Awards under this BAA are expected to take the form of Contracts, Grants, Cooperative Agreements and Other Transactions may also be awarded if appropriate. NRL encourages Educational Institutions, Small Businesses (SBs), Small Disadvantaged Business Concerns (SDBs) and Historically Black Colleges and Universities (HBCUs) and Minority Institutions (MIs) to submit proposals under this BAA. In order to conserve valuable offeror and Government resources, prospective offerors shall first submit a White Paper (WP) to the email address identified in the individual Summary Topics contained in Appendix 1, to include a rough cost estimate. If there is interest in the proposed research the offeror will be invited to submit a Formal Proposal. The selection of proposals for award will be based on a scientific review of proposals submitted in response to each BAA Summary Topic. The major purpose of the evaluation will be to determine the relative merit of the technical approach of each proposal. Business and contractual aspects, including proposed cost and cost realism, will also be considered as part of the evaluation. Selection of proposals for award will be based on the potential benefits to the Government weighed against the cost of the proposals, in view of the availability of funds. The complete BAA including proposal preparation instructions, award considerations, and evaluation criteria is also available at https://www.nrl.navy.mil/Doing-Business/Contracts/Broad-Agency-Announcements/ .

The purpose of this Notice of Funding Opportunity (NOFO) is to invite applications that bundle independent protocols for phase 1 clinical trials with phase 1b/phase 2a clinical trials to streamline the early-stage evaluation of promising pharmacological interventions for Alzheimer's disease (AD) and Alzheimer's disease-related Dementias (ADRD). Candidate interventions evaluated through this program, which can include small molecules or biologics for example, must engage non-amyloid/non-tau mechanisms and aim to address cognitive and/or neuropsychiatric symptoms in individuals across the spectrum from pre-symptomatic to more severe stages of disease. This NOFO uses the UG3/UH3 phased award mechanism and proposals must include prespecified, go/no-go safety and tolerability milestones that gate the advance from phase 1 to latter stages of clinical development.

This Notice of Funding Opportunity (NOFO) announces the renewal of the NIH Research Evaluation and Commercialization Hub (REACH) program, established to facilitate and accelerate the translation of academic biomedical discoveries into products that improve patient care and public health. Through this program, NIH will provide the qualifying institutions with the funds to seed the creation of academic entrepreneurship Hubs. Hubs will be responsible for providing innovators with both the initial investment and resources to support the proof-of-concept work and the mentorship in product development and commercialization needed to develop high priority technologies within the NIH's mission. Funded Hubs are intended to work as a consortium to enable: (1) the infrastructure for identifying the most promising technologies, (2) funding for product definition studies (e.g. feasibility studies, prototype development, proof-of-concept studies) provided to individual researchers, (3) access to resources and expertise in areas required for early stage technology development (including scientific, regulatory, reimbursement, business, legal, and project management), and (4) skills development and hands-on experience in entrepreneurship. Establishing public-private partnerships and providing additional non-federal funds will be critical for success. This is a Notice of Funding Opportunity (NOFO) for a Limited Competition that will invite applications from eligible organizations to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.

The purpose of this NOFO is to continue the Physiology of the Weight Reduced State (POWERS) clinical trial. The goal of POWERS is to understand the physiological processes underlying individual variability in weight regain following weight loss due to a lifestyle intervention. The continuation of POWERS will allow for the completion of the ongoing clinical trial and to conduct analysis of collected data and biospecimens. This NOFO invites a single source application from the Data Coordinating Center for the POWERS consortium.  Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application will be peer-reviewed, and only meritorious application(s) will be considered for funding.

Expected Outcome: The main objective of this call is to develop employees’ involvement in undertakings by raising awareness and contributing to the application of European Union law and policies in this area. The call aims at supporting projects which seek to help accompany through social dialogue at company level the significant changes driven by industry transitions and, in particular, the take-up and effective functioning of European Works Councils. The call shall focus on one or a limited number of topical challenges with a view to maximise both the individual and aggregated impact of the selected projects. Scope: Actions to promote European level and strengthened transnational cooperation between social partners that address the following themes would be expected: - to promote exchange and wider dissemination of knowledge and good practices and to launch actions aimed at supporting the setting up and good functioning of European Works Councils, including the promotion of gender balanced European Works Councils; - to support workers’ involvement in the anticipation and management of change and the prevention and resolution of disputes in the event of various forms of…

Proposals in the area of plasma physics submitted to the Division of Physics that are not governed by another solicitation (such as CAREER), should be submitted to the Division-wide solicitation: Division of Physics: Investigator-Initiated Research Projects . The Plasma Physics program participates in multiple NSF meta-programs such as the ECosytem for Leading Innovation in Plasma Science and Engineering (ECLIPSE) , Windows on the Universe: The Era of Multi-Messenger Astrophysics (WoU-MMA) , and Computational and Data-enabled Science and Engineering (CDS&E) . Topically appropriate proposals may also be submitted to the Plasma Physics program in response to NSF Dear Colleague Letters such as Critical Aspects of Sustainability (CAS): Innovative Solutions to Sustainable Chemistry (CAS-SC) . When permitted under an MOU between NSF and another funding agency or private foundation, NSF may share information from proposals submitted to this solicitation for consideration of joint funding, and may invite employees of such organizations to attend merit review panels as observers. MOUs of relevance to the Plasma Physics program presently exist with the Department of Energy/Office of Science, National Nuclear Security Administration, the Air Force Office of Scientific Research, the US-Israel Binational Science Foundation, the Czech Science Foundation, Deutsche Forschungsgemeinschaft (DFG, German Research Foundation), and the Swiss National Science Foundation. Plasma Physics is a study of matter and physical systems whose intrinsic properties are governed by collective interactions of large ensembles of free charged particles. 99.9% of the visible Universe is thought to consist of plasmas. The underlying physics of the collective behavior in plasmas has applications to space physics and astrophysics, materials science, applied mathematics, fusion science, accelerator science, and many branches of engineering. The Plasma Physics program supports research that can be categorized by several broad, sometimes overlapping, sub-areas of the discipline, including: magnetized plasmas in the laboratory, space, and astrophysical environments; high energy density plasmas; low temperature plasmas; dusty, ultra-cold, and otherwise strongly coupled plasmas; non-neutral plasmas; and intense field-matter interaction in plasmas. The focus of the Plasma Physics program is to generate an understanding of the fundamental principles governing the physical behavior of a plasma via collective interactions of large ensembles of free charged particles, as well as to improve the basic understanding of the plasma state as needed for other areas of science and engineering. Principal Investigators (PIs) are encouraged to consider including specific efforts to increase diversity of the plasma physics community and broaden participation of under-represented groups in Science, Technology, Engineering, and Mathematics (STEM) as Broader Impacts of proposed work. Development of new undergraduate and graduate plasma physics curricula, or curricula enhancement to include plasma physics topics in other courses, at institutions lacking such coursework is similarly encouraged. NSF recognizes that some research projects within this Program may require more than three years to realize demonstrable research outcomes. For such projects, PIs are encouraged to consult the above Program Director to discuss the possibility of submitting a proposal of 4- or 5-year duration. Some Plasma Physics-related activities are supported primarily by other NSF Programs. Proposals focused on the physical properties of individual or a small number of atoms or molecules, or optical physics, should be directed to the Atomic, Molecular, and Optical Physics Program within the Division of Physics. Proposals focused on understanding astrophysical systems should be directed to the Division of Astronomical Sciences. Proposals focused on understanding the Geospace environment or the Sun-Earth interactions should be directed to an appropriate program within the Geospace Section of the Division of Atmospheric and Geospace Sciences. Proposals focused on development of new materials using plasmas should be directed to an appropriate program in the Division of Materials Research. Proposals focused on plasma-assisted manufacturing should be directed to the Division of Civil, Mechanical and Manufacturing Innovation. Finally, proposals focused on use of plasmas for environmental and reaction engineering, environmental sustainability, combustion systems, or engineering of biomedical systems should be directed to an appropriate program within the Division of Chemical, Bioengineering, Environmental and Transport systems.

Summary: The intent of the fiscal year 2026 (FY26) Toxic Exposures Research Program (TERP) Translational Research Award (TRA) is to support translational research that will accelerate the movement of promising ideas in military-related toxic exposure research into clinical applications, including health care products, interventions, technologies and/or clinical practice guidelines. Translational research may be defined as an integration of basic science and clinical observations. New Approach Methodologies may also be used. Applications should provide evidence for the reciprocal transfer of information between basic and clinical science, or vice versa, in developing and implementing the research plan.   Distinctive Features: To encourage applications that include meaningful and productive collaborations, the FY26 TERP TRA includes a Partnering Principal Investigator Option (PPIO). One Principal Investigator (PI) is identified as the initiating PI, and an additional PI may be identified as a Partnering PI. If recommended for funding, each PI will be named on separate awards. The intent is to support interdisciplinary partnerships, such as those between clinicians and research scientists, that will accelerate the movement of promising ideas into clinical applications. Partnering should significantly advance the research beyond what would be possible through individual efforts. https://cdmrp.health.mil/pubs/press/2026/terppreann

The Astronomy and Astrophysics Research Grants (AAG) Program is an inclusive and flexible funding opportunity to support research in the astronomical sciences. The Program provides individual investigator and collaborative research grants for observational, theoretical, laboratory, and archival data studies in astronomy and astrophysics. The Program also considers proposals for projects and tools that enable or enhance astronomical research. Proposals may span multiple disciplines and/or areas of study and may utilize multiple techniques.

The goal of this NOFO is to support applications for novel theory and methods development that enable better understanding of how genetic and non-genetic factors contribute to complex trait variation across individuals, families, and populations. Approaches should be interdisciplinary drawing from the natural and social sciences, account for interdependencies across scales of biological, social, and ecological organization, and make extensive use of theory, modeling, and validation with available large-scale datasets.

Expected Outcome: The primary aim of this action is to create the conditions for a sustained dialogue between policymakers and individuals with lived experience of poverty, ensuring that those directly affected by poverty and/or social exclusion have a real and influential voice in the decisions that shape their lives. A core objective is to empower participants by providing them with the tools, confidence, and platforms needed to engage effectively in discussions on challenges related to combating poverty and social inclusion. This will come together with building trust and breaking down barriers between institutions and marginalised communities. The action will create a more inclusive and respectful exchange , where power imbalances are acknowledged and mitigated giving participants a clearer understanding of how policies are formed. Finally, the action will champion intersectionality : efforts will be made to amplify the voices of the most marginalised groups, ensuring that policies account for the diverse and overlapping challenges they face. By doing so, the initiative aims to create more equitable and inclusive solutions ; ones that reflect the complexities of poverty and…

The goal of this NOFO is to support R21 applications for novel theory and methods development that better delineate how genetic and non-genetic factors contribute to complex trait variation across individuals, families, and populations. Approaches should be interdisciplinary across the natural and social sciences, account for interdependencies across scales of biological, social, and ecological organization, and make extensive use of theory, simulations, and validation using available large-scale datasets

The Advanced Technologies and Instrumentation for the Astronomical Sciences (ATI) program provides individual investigator and collaborative research grants for the development of new technologies and instrumentation for use in ground-based astronomy and astrophysics.The program supports achieving the science objectives of the Division of Astronomical Sciences. The development of innovative, potentially transformative, technologies and instruments are sought, even at high technical risk.Supported categories include (but are not limited to):advanced technology development, concept feasibility studies, and specialized instrumentation to enable new observations that are difficult or impossible to obtain with existing means.Proposals may include hardware and/or software development and/or analysis to enable new types of astronomical observations. Access to the ATI supported technology and instrumentation development efforts by the US astronomical community is viewed as an important metric of success. An annual Principal Investigators meeting is planned to disseminate information between the funded research efforts.

Summary: The Orthopaedic Research Program (ORP) Applied Research Award (ARA) seeks applied research applications focused on advancing optimal treatment and restoration of function for individuals with orthopaedic injuries sustained during combat or service-related activities. Distinctive Features:  • Applied research is defined as work that refines concepts and ideas into potential solutions with a view toward evaluating technical feasibility of promising new knowledge products, pharmacologic agents, behavioral and rehabilitation interventions, diagnostic and therapeutic techniques, clinical guidance and/or emerging approaches and technologies. • Preliminary data is required. • Military relevance : the ORP expects that research findings benefit Service Members, their families, Veterans and the general public. • Clinical research is not allowed.

Summary: The fiscal year 2026 (FY26) Rare Cancers Research Program (RCRP) Resource and Community Development Award (RCDA) supports the development of research resources and clinical or preclinical datasets that will advance the field of rare cancers research and ultimately improve outcomes for individuals with rare cancers. Research supporting this funding opportunity should fill one of the following major gaps: Lack of research and clinical resources, including patient tissues, cell and tumor models. Lack of communication and dissemination strategies within scientific and patient communities for sharing rare cancers research and clinical findings. Lack of infrastructure for sharing data and other resources. Lack of therapeutics and mechanistic research to inform treatment development. Distinctive Features: Documentation of plans for engagement and partnerships with Patient Advocates throughout the life cycle of the research study from development of the research question through execution of the study. Community building and enhancement are key components. A description of the dissemination and sustainability of the platform for scientific and/or clinical and patient community is required. Preliminary data are not required but may be included to address feasibility.

The National Institutes of Health (NIH) intends to renew the Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR) research network. This renewed network will include several individual research projects supported by one central Coordination Center. The goal of the network is to test new and improved approaches for people who have both chronic pain (CP) and opioid use disorder (OUD). These approaches should lead to meaningful improvements in how health systems deliver care. The network will be part of the NIH’s Helping to End Addiction Long-term (HEAL®) Initiative to speed the development and implementation of scientific solutions to the national opioid public health crisis. The NIH HEAL Initiative will bolster research across NIH to (1) improve treatment and prevention of opioid misuse and OUD and (2) enhance pain management.

The National Institutes of Health (NIH) intends to renew the Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR) research network. This renewal consists of individual research projects, which will be supported by a single Coordination Center. This network is intended to test new innovations that integrate evidence based treatments for chronic pain (CP) and opioid use disorder (OUD). This research will characterize or modify factors that impact wide-scale adoption and sustained use of effective treatments at this intersection. The network will be part of the NIH’s Helping to End Addiction Long-term (HEAL®) Initiative to speed the development and implementation of scientific solutions to the national opioid public health crisis. The NIH HEAL Initiative will bolster research across NIH to (1) improve treatment and prevention of opioid misuse and OUD and (2) enhance pain management. This notice of funding opportunity (NOFO) seeks applications for a single Building Engagement, Assistance, Capacity, Outreach, and Networks (BEACON) Center. The BEACON Center will provide overall network coordination support; research education activities to build capacity at the intersection of CP, OUD, and implementation science; annual survey/qualitative activities to understand different barriers and attitudes impacting access and sustained use of integrated CP and OUD service delivery; and develop key resources for stakeholders that can inform/improve sustainability and scalability of evidence-based practices, including findings and resources from IMPOWR Phase I.

The purpose of the Tribal Undergraduate to Graduate Research Training and Leadership Experiences (TURTLE) program is to fund federally recognized American Indian/Alaska Native (AI/AN) Tribes, tribal colleges or universities, Tribal health programs, or Tribal organizations (collectively termed, eligible Tribal Entities) to identify and develop a pool of scientists to conduct research on AI/AN health and health disparities. Through this Notice of Funding Opportunity (NOFO), NIGMS will provide support for a phased award to eligible AI/AN Tribal Entities to develop (UE5) and implement (T32) effective training and mentoring activities for research-oriented individuals earning a doctoral degree in a biomedical research field at a variety of institutions across the United States and territories. The overall purpose is to support the development of individuals who have the technical, operational, and professional skills required to conduct AI/AN health research in a culturally appropriate, ethically responsible and rigorous manner, to complete Ph.D.s in a biomedical field, and to transition into careers in the biomedical research workforce.

Since 1990, CDC's Division of Cancer Prevention and Control (DCPC) has been working with national organizations, state, territory, freely associated state, and tribal health agencies, and other key groups to develop, implement, and promote effective strategies for preventing and controlling cancer. DCPC's overall mission is to work toward having all people free of cancer while improving health outcomes through prevention, screening, and ongoing care for cancer survivors. DCPC supports comprehensive cancer control, a philosophical approach that brings together partners and other organizations to collectively address a community's cancer burden in a much more impactful way than any one organization could accomplish alone. This NOFO will fund eligible applicants to facilitate collaborative planning and implementation of evidence-based cancer surveillance, prevention, and control strategies in communities that improve the provision of clinical preventive services, and cancer survivorship. Ultimately, a successful implementation of the work described in this NOFO will demonstrate that by the three programs working together through partnerships, coordination of resources and efforts, consistent communication, and community involvement, we will come that much closer to the division's mission of "All People Free of Cancer." This program takes a comprehensive, coordinated approach to achieve these goals. It supports breast and cervical cancer screening and diagnostic services, cancer control plan implementation by coalitions, and surveillance programs to monitor and report cancer burden. These goals will be accomplished by funding three national programs: Program 1: National Breast and Cervical Cancer Early Detection Program (NBCCEDP) supports clinical services for women with low incomes who do not have adequate insurance and implementation of evidence-based interventions in the clinics that serve them. Component A: Supports breast and cervical cancer screening and diagnostic follow-up for women with low incomes who do not have adequate insurance. Component B: (Optional) Supports implementation of evidence-based interventions (EBIs) shown to increase breast and cervical cancer screening. Program 2: National Comprehensive Cancer Control Program (NCCCP) supports cancer coalition efforts that use their individual and collective resources to plan and implement evidence-based strategies as described in jurisdiction-wide cancer plans. Program 3: National Program of Cancer Registries (NPCR) supports the implementation of a population-based central cancer registry program.

The purpose of the Tribal Undergraduate to Graduate Research Training and Leadership Experiences (TURTLE) program is to fund federally recognized American Indian/Alaska Native (AI/AN) Tribes, tribal colleges or universities, Tribal health programs, or Tribal organizations (collectively termed, eligible Tribal Entities) to identify and develop a pool of scientists to conduct research on AI/AN health and health disparities. Through this Notice of Funding Opportunity (NOFO), NIGMS will provide support for a phased award to eligible AI/AN Tribal Entities to develop (UE5) and implement (T34) effective training and mentoring activities for research-oriented individuals earning a bachelor's degree in a biomedically-relevant field at a variety of institutions across the United States and territories. The overall purpose is to support the development of individuals who have the technical, operational, and professional skills required to conduct AI/AN health research in a culturally appropriate, ethically responsible and rigorous manner, to complete a bachelor's degree in a biomedical field, and ultimately to transition into careers in the biomedical research workforce.

Summary: The fiscal year 2026 (FY26) Autism Research Program (ARP) Idea Development Award supports the development of innovative, high-risk/high-reward research that could lead to critical discoveries or major advancements that will accelerate progress in improving outcomes for Autistic individuals. This award mechanism is designed to support innovative ideas with the potential to yield impactful data and new avenues of investigation. Distinctive Features: Applications are strongly encouraged to address one of the FY26 ARP Idea Development Award Areas of Interest or provide justification that the proposed research addresses a critical problem, question, or need in autism. Partnering Principal Investigator (PI) Option: The Partnering PI Option is structured so that two investigators, each of whom will be designated as a PI, will work synergistically on a single project. The results of this partnering project should significantly advance the research beyond what would be possible through individual efforts.

Summary: The fiscal year 2026 (FY26) Autism Research Program (ARP) Clinical Trial Award supports the rapid implementation of clinical trials with the potential to have a significant impact on the treatment or management of autism. Clinical trials may be designed to evaluate promising new products, pharmacologic agents (drugs or biologics), devices, clinical guidance and/or emerging approaches and technologies. Proposed projects may range from small proof-of-concept trials (e.g., pilot, first-in-human, phase 0) to demonstrate the feasibility or inform the design of more advanced trials through large-scale trials to determine efficacy in relevant patient populations. Distinctive Features: Applications are strongly encouraged to address one of the FY26 ARP Clinical Trial Award Areas of Interest. Partnering Principal Investigator (PI) Option for Early-Career Investigator: The FY26 Clinical Trial Award mechanism is offering a higher level of funding for applications that propose to partner an experienced PI (i.e., Initiating PI) with an Early-Career Investigator (i.e., Partnering PI) wishing to pursue a career in autism clinical trial research. FY26 Clinical Trial Award submissions are required to include community collaborations to optimize research impact. Research teams are therefore required to establish and utilize effective and equitable collaborations and partnerships with community members to maximize the translational and impact potential of the proposed research. Applications to the FY26 ARP Clinical Trial Award are expected to name at least one community partner (e.g., Autistic individual or caregiver, representatives of community-based organizations) who will provide advice and consultation throughout the planning and implementation of the research project. Interactions with other team members should be well integrated and ongoing, not limited to attending seminars and semi-annual meetings (see Attachment 12, Community Collaboration Plan).

Summary: The fiscal year 2026 (FY26) Military Burn Research Program (MBRP) Technology/Therapeutic Development Award (TTDA) is a burn-focused, product-driven award mechanism intended to provide support for the translation of promising preclinical findings into burn products for clinical application in an austere, resource-limited, distributed operational environment. Distinctive Features: The technology or therapeutic product(s) to be developed must be product-oriented (e.g., medical device, drug, or clinical practice guidelines involving a therapeutic or technology). The product(s) to be developed may be tangible or knowledge supporting the development of a tangible product and must address one or more of the FY26 MBRP TTDA focus areas. Knowledge products are allowable, provided that the knowledge is applicable to a technology or therapeutic under development. (A “knowledge product” is a non-tangible, non-materiel product that results from research with the potential to improve individual or public health.) ·         New for FY26: The FY26 MBRP TTDA offers a Mentorship Option at a higher funding level to support a synergistic relationship between an experienced researcher (Mentor) and one to two junior researchers (Mentees). The dual purpose of this award is to fund a primary research study addressing a critical gap in combat burn care while simultaneously fostering the development of the next generation of military burn research leaders.

Summary: The fiscal year 2026 (FY26) Autism Research Program (ARP) Career Development Award supports early-career, independent investigators and/or the transition of established investigators from other research fields to conduct innovative, high-impact ideas or early-phase, proof-of-principle clinical trials with the potential to have a major impact on autism. Distinctive Features: Applications are strongly encouraged to address one of the FY26 ARP Career Development Award Areas of Interest or provide justification that the proposed research addresses a critical problem, question, or need in autism. FY26 Career Development Award submissions with a pilot clinical trial component are required to include community collaborations to optimize research impact. Applications are expected to name at least one community partner (e.g., an Autistic individual or caregiver, representatives of community-based organizations) who will provide advice and consultation throughout the planning and implementation of the research project.

The Linguistics Program supports basic science in the domain of human language, encompassing investigations of the grammatical properties of individual human languages, and of natural language in general. Research areas include syntax, semantics, morphology, phonetics and phonology. The program encourages projects that are interdisciplinary in methodological or theoretical perspective, and that address questions that cross disciplinary boundaries, such as (but not limited to): What are the psychological processes involved in the production, perception, and comprehension of language? What are the computational properties of language and/or the language processor that make fluent production, incremental comprehension or rapid learning possible? How do the acoustic and physiological properties of speech inform our theories of natural language and/or language processing? What role does human neurobiology play in shaping the various grammatical properties of language? How does language develop in natural learning contexts across the life-span? What social and cultural factors underlie language variation and change? Because NSF's mandate is to support basic research, the Linguistics Program does not fund research that takes as its primary goal improved clinical practice or applied policy, nor does it support work to develop or assess pedagogical methods or tools for language instruction. The Linguistics Program accepts proposals for a variety of project types: research proposals from scholars with PhDs or equivalent degrees, proposals for Doctoral Dissertation Research Improvement (LING-DDRI) awards, and CAREER proposals. We will also consider proposals for conferences. Funding requests for conference support should be submitted in accordance with the Conference Proposals section of Chapter II of NSF's Proposal & Award Policies & Procedures Guide (PAPPG) . NSF's Division of Behavioral and Cognitive Sciences (BCS), in partnership with the National Endowment for the Humanities and in collaboration with programs in other NSF Directorates, supports efforts to develop and advance knowledge and infrastructure that will enable the analysis of languages that are both understudied and at risk of falling out of use. In recognition of the critical relevance of these languages to understanding the range and limits of human linguistic and cultural variation, BCS accepts research and dissertation proposals in response to solicitations NSF Dynamic Language Infrastructure - NEH Documenting Endangered Languages (DLI-DEL) and Dynamic Language Infrastructure - Doctoral Dissertation Research Improvement Grants (DLI-DDRI) . For more information about Multidisciplinary Research and Training Opportunities, please visit the SBE Office of Multidisciplinary Activities web site.

The Decision, Risk and Management Sciences Program (DRMS) supports scientific research directed at increasing understanding and effectiveness of decision making by individuals, groups, organizations and society. DRMS supports research with solid foundations in theories and methods of the social and behavioral sciences. This social and behavioral science research should advance knowledge, address fundamental scientific and societal issues and have strong broader impacts. DRMS funds disciplinary and interdisciplinary research, doctoral dissertation research improvement grants (DDRIGs) and conferences in the following areas: judgment and decision making; decision analysis and decision aids; risk analysis, perception and communication; societal and public-policy decision making; management science and organizational design. The program supports the use of the RAPID funding mechanism for research that involves ephemeral data, typically tied to disasters or other unanticipated events. Much less frequently, the program also supports highly unusual, proof-of-concept, high-risk projects that are potentially transformational (Early Concept Grants for Exploratory Research – EAGER). For detailed information concerning RAPID and EAGER grants, please review Chapter II.E of the  NSF PAPPG . All research must be grounded in theory and generalizable. Purely algorithmic management-science proposals should be submitted to the  Operations Engineering (OE)  Program rather than to DRMS. Decision, Risk and Management Sciences offers Doctoral Dissertation Research Improvement Grants (DDRIGs) to improve the quality of dissertation research. For detailed guidelines on preparing a DDRIG proposal, consult the separate   DRMS-DDRIG solicitation .

The primary aim of the Mathematical Sciences Infrastructure Program is to foster the continuing health of the mathematical sciences research community as a whole. In addition, the program complements the Workforce Program in the Mathematical Sciences in its goal to increase the number of well-prepared U.S. based individuals who successfully pursue careers in the mathematical sciences and in other professions in which expertise in the mathematical sciences plays an increasingly important role. The DMS Infrastructure program invites projects that support core research in the mathematical sciences, including: 1) novel projects supporting research infrastructure across the mathematical sciences community; 2) training projects complementing the Workforce Program, and 3) conference, workshop, and travel support requests that include cross-disciplinary activities or have an impact at the national scale.  Proposals under this solicitation submitted to DMS Infrastructure must show engagement in developing or enhancing the mathematical sciences research infrastructure in the U.S., including, but not limited to, broadening participation activities; professional development training; or involvement of students and early career researchers. Proposals must explain the regional or national scale impact of the activity that goes substantially beyond the submitting institution or the location of the event. Full proposals (with exception of conference proposals, which are subject to lead-time requirements) must be submitted close to one of the Full Proposal Target Dates. See below for more information about each category of Infrastructure projects. (1)  Novel projects that serve to strengthen the research infrastructure: The DMS Infrastructure Program will consider novel projects that support and strengthen the research infrastructure across the mathematical sciences community. These projects most often cut across multiple sub-disciplines supported by DMS or involve interdisciplinary collaborations. The main goal of these projects should be to create a new research infrastructure or substantially enhance or transform an existing infrastructure with regional or national impact that goes substantially beyond the submitting institution or the location of the project.   Full proposals must be submitted by the Full Proposal Target Date. (2)  Training projects: Training proposals submitted to DMS Infrastructure must not fit into one of the areas covered by solicitations in the Workforce Program in the Mathematical Sciences ; they must be submitted by the Full Proposal Target Date; and they must: A. Include a core research component for trainees in mathematical sciences; B. Demonstrate promise for an impact at the regional or national scale that goes substantially beyond the submitting institution or the location of the project; C. Satisfy at least one of the following criteria: i. Serve as models to be replicated, ii. Promote partnerships with non-academic entities, minority-serving institutions, or community colleges, or  iii. Include a substantial broadening participation initiative. In addition, all proposals of this type must clearly identify: Goals to be achieved; Specific new activities to be conducted, the way in which these address the goals, and the way in which the activities significantly differ from or enhance common practice; Measurable outcomes for the project; Plans and methods for assessment of progress toward the goals to be achieved, and for evaluation of the success of the activity; Recruitment, selection, and retention plans for participants, including members of underrepresented groups; Sustainability plans to continue the pursuit of the project's goals when funding terminates; and A budget commensurate with the proposed activity. 3) Conferences, Symposia, Working Research Sessions, Travel Support Requests : Principal Investigators should carefully read the program solicitation  Conferences and Workshops in the Mathematical Sciences  to obtain important information regarding the substance of proposals for conferences, workshops, summer/winter schools, international travel support, and similar activities. Conference/workshop proposals that concern topics within a particular subdiscipline of mathematics or statistics should be submitted to the appropriate DMS disciplinary program(s). These submissions are subject to the lead-time requirements specified by the disciplinary program(s); see the program web pages listed on the  DMS home page . Conference/workshop proposals may be submitted to the DMS Infrastructure program only if the intended topical areas span a wide range of the mathematical sciences and are consequently not within the scope of DMS disciplinary programs. The required lead time for submission of such proposals is: 6 months in advance of the meeting date for proposals requesting no more than $50,000 to support a domestic meeting; 9 months in advance of the meeting date for proposals requesting more than $50,000 to support a domestic meeting; 12 months in advance of the meeting date for proposals requesting support for participation in a meeting taking place outside the United States.       

The purpose of this Funding Opportunity Announcement (FOA) is to support high priority research at the intersection of HIV and substance use. This FOA invites innovative research projects with the potential to open new areas of HIV/AIDS research and/or lead to new avenues for prevention, treatment and cure of HIV among people who use drugs (PWUD). Applications submitted under this FOA are required to have a detailed research plan, preliminary data, and a clear description of the nexus with substance use. This FOA is open to both individual researchers and research teams and includes all areas of research from basic science to clinical and implementation research. All studies must focus on NIH HIV/AIDS Research Priorities: NOT-OD-20-018: UPDATE: NIH HIV/AIDS Research Priorities and Guidelines for Determining HIV/AIDS Funding.

Science of Learning and Augmented Intelligence (SL) supports potentially transformative research that develops basic theoretical insights and fundamental knowledge about principles, processes and mechanisms of learning, and about augmented intelligence — how human cognitive function can be augmented through interactions with others or with technology, or through variations in context.  The program supports research addressing learning in individuals and in groups, across a wide range of domains at one or more levels of analysis, including molecular and cellular mechanisms; brain systems; cognitive, affective and behavioral processes; and social and cultural influences.  The program also supports research on augmented intelligence that clearly articulates principled ways in which human approaches to learning and related processes, such as in design, complex decision-making and problem-solving, can be improved through interactions with others or through the use of artificial intelligence in technology. These could include ways of using knowledge about human functioning to improve the design of collaborative technologies that have the capacity to learn to adapt to humans. For both aspects of the program, there is special interest in collaborative and collective models of learning and intelligence that are supported by the unprecedented speed and scale of technological connectivity. This includes emphasis on how people and technology working together in new ways and at scale can achieve more than either can attain alone. The program also seeks explanations for how the emergent intelligence of groups, organizations and networks intersects with processes of learning, behavior and cognition in individuals.    Projects that are convergent or interdisciplinary may be especially valuable in advancing basic understanding of these areas, but research within a single discipline or methodology is also appropriate. Connections between proposed research and specific technological, educational and workforce applications will be considered as valuable broader impacts but are not necessarily central to the intellectual merit of proposed research. The program supports a variety of approaches, including experiments, field studies, surveys, computational modeling, and artificial intelligence or machine learning methods. Examples of general research questions within scope of Science of Learning and Augmented Intelligence (SL) include: What are the underlying mechanisms that support transfer of learning from one context to another or from one domain to another? How is learning generalized from a small set of specific experiences? What is the basis for robust learning that is resilient against potential interference from new experiences? How is learning consolidated and reconsolidated from transient experience to stable memory? How do human interactions with technologies, imbued with artificial intelligence, provide improved human task performance? What models best describe the interplay of the individual and collaborative processes that lead to co-creation of knowledge and collective intelligence? In what ways do the capacities and constraints of human cognition inform improved methods of human-artificial intelligence collaboration?  How can we integrate research findings and insights across levels of analysis, relating understanding of cellular and molecular mechanisms of learning in the neurons, to circuit and systems-level computations of learning in the brain, to cognitive, affective, social and behavioral processes of learning? What is the relationship between assembly of new networks (development) and learning new knowledge in a maturing or mature brain? What concepts, tools (including Big Data, machine learning, and other computational models) or questions will provide the most productive linkages across levels of analysis? How can insights from biological learners contribute and derive new theoretical perspectives to artificial intelligence, neuromorphic engineering, materials science and nanotechnology? How can the ability of biological systems to learn from relatively few examples improve efficiency of artificial systems? How do learning systems (biological and artificial) address complex issues of causal reasoning? How can knowledge about the ways in which humans learn help in the design of human-machine interfaces?

This Notice of Funding Opportunity Announcement (NOFO) invites grant applications for Environmental Health Sciences Core Centers (EHSCC). As intellectual hubs for environmental health science research, the EHSCC's are expected to be the thought leaders for the field and advance the goals of the 2025-2029 NIEHS Strategic Plan (http://www.niehs.nih.gov/about/strategicplan/). The Core Centers provide critical research infrastructure, shared facilities, services and/or resources, to groups of investigators conducting environmental health sciences research. An EHSCC enables researchers to conduct their independently-funded individual and/or collaborative research projects more efficiently and/or more effectively. The overall goal of an EHSCC is to identify and capitalize on emerging issues that advance improving the understanding of the relationships among environmental exposures, human biology, and disease. The EHSCC supports community engagement and translational research as key approaches to improving public health.

The objectives for the use of cooperative agriculture in the National Wildlife Refuge System (NWRS) are: production or modification of specific cover types or growing methods that meet the life history requirements of species for which we have established objectives (e.g., waterfowl production); production of foods for wildlife species for which we have established objectives; and/or maintenance, rehabilitation, or reestablishment of natural habitat. Cooperative agriculture is when a person or entity conducts agricultural practices on NWRS lands in support of the Service’s conservation and resource management objectives and there is substantial involvement between the Service and that person or entity. The NWRS uses cooperative agreements, known as Cooperative Agriculture Agreements (CAAs), as the legal instruments to formalize the agreement between the Service and the program participant. The cost-sharing of a person or entity in cooperative agricultural on NWRS lands can vary depending on the needs and objectives of the particular NWRS land. For example, the Service may provide the cooperator with the right to perform agricultural practices on NWRS land and a percentage of any resulting crop yield, as well as the ability to use Service water, equipment, and/or refuge staff. In exchange, the cooperator may provide the Service with labor, equipment, and materials; a percentage of any resulting crop yield; and/or maintenance, rehabilitation, or reestablishment of specific habitat conditions on NWRS lands. In addition to or instead of cost-sharing, the Service may accept bids for payment for the person or entity’s agriculture use (e.g. haying or grazing) on NWRS lands in compliance with the Refuge Revenue Sharing Act. This is a nonfinancial assistance program. No Federal funds are obligated or awarded to program participants. Because a CAA is not a financial assistance award, it is not subject to the regulations at 2 CFR 200 or policy in parts 515 and 516 of the Fish and Wildlife Service Manual.

The purpose of the NHLBI Emerging Investigator Award (EIA) is to promote scientific productivity and innovation by providing long-term support and increased flexibility to experienced Program Directors/Principal Investigators (PDs/PIs) who are currently PDs/PIs on at least two NHLBI R01-equivalent awards and whose outstanding record of research demonstrates their ability to make major contributions to heart, lung, blood and sleep (HLBS) research. The EIA is intended to support a research program, rather than a research project, by providing the primary and most likely sole source of NHLBI funding on individual grant awards. The EIA will support the research program of NHLBI-funded investigators for up to seven years. The EIA will provide investigators increased freedom to conduct research that breaks new ground or extends previous discoveries in new directions. It will also allow PDs/PIs to take greater risks and to pursue research that requires a longer timeframe. Research supported by the EIA must be within the scope of the NHLBI mission (http://www.nhlbi.nih.gov/about/org/mission).

The purpose of the NHLBI Outstanding Investigator Award (OIA) is to promote scientific productivity and innovation by providing long-term support and increased flexibility to experienced Program Directors/Principal Investigators (PDs/PIs) who are currently PDs/PIs on at least two NHLBI R01-equivalent awards and whose outstanding record of research demonstrates their ability to make major contributions to heart, lung, blood and sleep (HLBS) research. The OIA is intended to support a research program, rather than a research project, by providing the primary and most likely sole source of NHLBI funding on individual grant awards. The OIA will support the research program of NHLBI-funded investigators for up to seven years. The OIA will provide investigators increased freedom to conduct research that breaks new ground or extends previous discoveries in new directions. It will also allow PDs/PIs to take greater risks and to pursue research that requires a longer timeframe. Research supported by the OIA must be within the scope of the NHLBI mission (https://www.nhlbi.nih.gov/about/mission-statement). It is anticipated that the OIA will: Provide a stable funding environment, thereby improving productivity and facilitating nimble, ambitious, creative research; Accelerate scientific innovation by enabling flexibility in pursuing new research directions as they arise, since PDs/PIs will not be bound to specific aims proposed in advance of the studies; Reduce the time researchers spend writing grant applications and managing multiple grant awards, thereby allowing more time to be devoted to conducting research; Facilitate commitment of PDs/PIs to research through increased stability of funding; and Enable PDs/PIs to devote more time and energy to mentoring students and junior scientists and providing scientific service.

The purpose of the NIH Mentored Research Scientist Development Award (K01) is to provide support and protected time (three to five years) for an intensive, supervised career development experience in the biomedical, behavioral, or clinical sciences leading to research independence. Although all of the participating NIH Institutes and Centers (ICs) use this support mechanism to support career development experiences that lead to research independence, some ICs use the K01 award for individuals who propose to train in a new field or for individuals who have had a hiatus in their research career because of illness or pressing family circumstances. Other ICs use the K01 to support career development in specific fields.This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or a separate ancillary clinical trial. Applicants to this FOA are permitted to propose research experience in a clinical trial led by a mentor or co-mentor. Applicants proposing a clinical trial or an ancillary clinical trial as lead investigator, should apply to the companion NOFO.

The purpose of the NIH Mentored Patient-Oriented Research Career Development Award (K23) is to support the career development of individuals with a clinical doctoral degree who have made a commitment to focus their research endeavors on patient-oriented research.

The primary purpose of the NIH Mentored Clinical Scientist Research Career Development Awards (K08) program is to prepare qualified individuals for careers that have a significant impact on the health-related research needs of the Nation. This program represents the continuation of a long-standing NIH program that provides support and "protected time" to individuals with a clinical doctoral degree for an intensive, supervised research career development experience in the fields of biomedical and behavioral research, including translational research.

The purpose of the NIH Independent Scientist Award (K02) is to foster the development of outstanding scientists and enable them to expand their potential to make significant contributions to their field of research. The K02 award provides three to five years of salary support and "protected time" for newly independent scientists who can demonstrate the need for a period of intensive research focus as a means of enhancing their research careers. Each independent scientist career award program must be tailored to meet the individual needs of the candidate.This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing to serve as the lead investigator of an independent clinical trial, a clinical trial feasibility study, or a separate ancillary clinical trial, as part of their research and career development. Applicants not planning an independent clinical trial, or proposing to gain research experience in a clinical trial led by another investigator, must apply to companion FOA

The purpose of the NIH Independent Scientist Award (K02) is to foster the development of outstanding scientists and enable them to expand their potential to make significant contributions to their field of research. The K02 award provides three to five years of salary support and "protected time" for newly independent scientists who can demonstrate the need for a period of intensive research focus as a means of enhancing their research careers. Each independent scientist career award program must be tailored to meet the individual needs of the candidate.This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or a separate ancillary clinical trial. Applicants to this FOA are permitted to propose research experience in a clinical trial led by another investigator. Applicants proposing a clinical trial or an ancillary clinical trial as lead investigator, should apply to the companion FOA

The purpose of the NIH Mentored Research Scientist Development Award (K01) is to provide support and protected time (three to five years) for an intensive, supervised career development experience in the biomedical, behavioral, or clinical sciences leading to research independence. Although all of the participating NIH Institutes and Centers (ICs) use this support mechanism to support career development experiences that lead to research independence, some ICs use the K01 award for individuals who propose to train in a new field or for individuals who have had a hiatus in their research career because of illness or pressing family circumstances.

The primary purpose of the NIH Mentored Clinical Scientist Research Career Development Awards (K08) program is to prepare qualified individuals for careers that have a significant impact on the health-related research needs of the Nation. This program represents the continuation of a long-standing NIH program that provides support and "protected time" to individuals with a clinical doctoral degree for an intensive, supervised research career development experience in the fields of biomedical and behavioral research, including translational research.

The purpose of the NIH Mentored Patient-Oriented Research Career Development Award (K23) is to support the career development of individuals with a clinical doctoral degree who have made a commitment to focus their research endeavors on patient-oriented research.

The Office of Disease Prevention (ODP) and participating National Institutes of Health (NIH) Institutes, Centers, and Offices (ICOs) are issuing this notice of funding opportunity (NOFO) seeking applications to test innovative approaches to implementing SBIRT/P for alcohol, tobacco, and other drugs (ATOD) use and misuse in adult populations that experience health disparities. SBIRT/P, (a term used for purposes of this funding announcement), involves screening individuals for risk of ATOD use and misuse, briefly intervening with a conversation about harmful substance use, and referring individuals for treatment or preventive services, as needed.  Proposed research should include prospective tests of SBIRT/P and should leverage collaborations with healthcare and community partners. Specific research interests of participating NIH ICOs are detailed within.  

The goal of this notice of funding opportunity (NOFO) is to address the opioid crisis and/or overdose events by supporting action-oriented research, accelerating the translation of addiction epidemiology, prevention, treatment services, and recovery research to practice. Proposed studies may target the individual, provider, organizational, community, or system level. This initiative prioritizes replicable and scalable approaches for accelerating the routine use of effective, evidence-based prevention, treatment and recovery interventions and services. The translation of research to practice and research relevant to chronic pain comorbid with substance use is also a priority. Research may deploy a variety of methods and approaches, including but not limited to identifying and characterizing malleable factors, developing and testing interventions and implementation strategies, deploying and testing collaborative data science approaches, and/or developing and testing approaches that integrate the collaboration of researchers and decision-makers at any levels (e.g., clinical-, health system-, public health- or policy-level).

The Maximizing Investigators' Research Award (MIRA) provides support for individual investigators for research within the scientific mission of NIGMS via a single grant to achieve the following:Increase the stability of funding for NIGMS-supported investigators, which could enhance their ability to take on ambitious scientific projects and approach problems more creatively;Increase flexibility for investigators to follow important new research directions within the NIGMS mission as opportunities arise, rather than being bound to specific aims proposed in advance of the studies;More widely distribute funding among the nation's highly talented and promising investigators to increase overall scientific productivity and the chances for important breakthroughs;Reduce the time spent by researchers writing and reviewing grant applications, allowing them to spend more time conducting research;Reduce the administrative burden associated with a PD/PI managing multiple NIGMS research grants; andEnable PD(s)/PI(s) to devote more time and energy to mentoring junior scientists in a more stable research environment.This NOFO invites applications from eligible NIGMS-funded investigators and from New Investigators proposing research that is aligned with NIGMS' scientific mission. The NOFO also allows renewal applications from all current MIRA grantees (including those previously funded as Early-Stage Investigators). Current Early-Stage Investigators (ESIs) should apply through the ESI MIRA NOFO, not this NOFO.

This funding opportunity supports transformative, mechanistic research aimed at understanding how the human brain functions. Applications should seek to reveal how the dynamic activity of individual neurons and ensembles of neurons within spatially organized brain networks gives rise to internal experiences, such as sensations, perceptions, emotions, thoughts, and memories, as well as to observable motor and social behaviors.  To achieve fundamental mechanistic insights into human brain function, proposed studies are expected to leverage opportunities made possible by invasive surgical procedures in humans, such as intracranial recording or stimulation. These investigations may be enhanced by incorporating complementary experimental models or systems that provide access to knowledge, techniques, or resources not otherwise available in human neuroscience research. Such integration is encouraged to strengthen the mechanistic understanding of human brain function and to connect discoveries across species and biological scales. This program builds on cutting-edge advances enabled by the BRAIN Initiative and the broader neuroscience community. Projects supported through this opportunity are expected to produce transformative outcomes by the end of the funding period. Approaches should be rigorous, mechanistic, and innovative by (1) maximizing opportunities to conduct innovative in vivo human neuroscience research made available by direct access to the human brain from invasive surgical procedures, (2) employing approaches guided by specified theoretical constructs and/or quantitative, mechanistic models. Funded investigators will join a consortium working group, coordinated by the NIH, to identify consensus standards of practice, including neuroethical considerations, to collect and provide data for ancillary studies, and to aggregate and standardize data for dissemination among the wider scientific community.

The National Center for Advancing Translational Sciences (NCATS) will award Ruth L. Kirschstein National Research Service Award (NRSA) Postdoctoral Institutional Research Training Grants for the Clinical and Translational Science Awards (CTSA) Program (T32) to eligible institutions to create, provide, and disseminate clinical and translational science training and career support programs that enhance postdoctoral research training of individuals with doctoral degrees (these include, but are not limited to, the following: D.M.D., DC, DO, DVM., OD, DPM, ScD, EngD, DrPH, DNSc, DPT, PharmD, ND [Doctor of Naturopathy], DSW, PsyD, as well as a doctoral degree in nursing research) and help ensure a heterogenous pool of clinical and translational scientists trainees who are equipped with the knowledge, skills and abilities to advance diagnostics, therapeutics, clinical interventions, and behavioral modifications that improve health and support meaningful translational science research projects that address demonstrable needs among stakeholder communities.

This Notice of Funding Opportunity (NOFO) will support students at institutions with NIH-funded institutional predoctoral dual-degree training programs. The purpose of the Kirschstein-NRSA, dual-doctoral degree, predoctoral fellowship (F30) is to enhance the integrated research and clinical training of promising predoctoral students, who are matriculated in a combined MD/PhD or other dual-doctoral degree training program (e.g. DO/PhD, DDS/PhD, AuD/PhD, DVM/PhD), and who intend careers as physician/clinician-scientists. Candidates must propose an integrated research and clinical training plan and a dissertation research project in scientific health-related fields relevant to the missions of the participating NIH Institutes and Centers. The fellowship experience is expected to clearly enhance the individual's potential to develop into a productive, independent physician/clinician-scientist. This Notice of Funding Opportunity (NOFO) is designed specifically for candidates proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or an ancillary clinical trial, but does allow candidates to propose research experience in a clinical trial led by a sponsor or co-sponsor.

The purpose of the Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral (Parent F31) award is to enable promising predoctoral students will obtain individualized, mentored research training from outstanding faculty sponsors while conducting dissertation research projects in scientific health-related fields relevant to the missions of the participating NIH Institutes and Centers. The proposed mentored research training must reflect the candidates dissertation research project and is expected to clearly enhance the individuals potential to develop into a productive, independent research scientist. This Notice of Funding Opportunity (NOFO) does not allow candidates to propose to lead an independent clinical trial but does allow candidates to propose research experience in a clinical trial led by a sponsor or co-sponsor.

The National Institutes of Health (NIH) awards senior individual research training fellowships to experienced scientists who wish to make major changes in the direction of their research careers or who wish to broaden their scientific background by acquiring new research capabilities as independent investigators in research fields relevant to the missions of participating NIH Institutes and Centers.

The National Institutes of Health (NIH) Research Education Program supports research education activities in the mission areas of the NIH. The overarching goal of the Research Education program is to:Support educational activities that complement and/or enhance training of a workforce to meet the nation's biomedical, behavioral and clinical research needs;Help recruit individuals with specific specialty or disciplinary backgrounds to research careers in biomedical, behavioral and clinical sciences; andFoster a better understanding of biomedical, behavioral and clinical research and its implications.

The National Center for Advancing Translational Sciences (NCATS) will award Ruth L. Kirschstein National Research Service Award (NRSA) Predoctoral Institutional Research Training Grants for the Clinical and Translational Science Awards (CTSA) Program (T32) to eligibleinstitutions to create, provide, and disseminate clinical and translational science training and career support programs for individuals seeking a PhD or an equivalent research health professional degree and help ensure a heterogenous pool of clinical and translational scientist trainees who are equipped with the knowledge, skills and abilities (KSAs) to advance diagnostics, therapeutics, clinical interventions, and behavioral modifications aimed at improving health and support meaningful translational science research projects that address demonstrable needs among stakeholder communities.

This Notice of Funding Opportunity (NOFO) supports interdisciplinary research teams of three to six Program Directors/Principal Investigators (PDs/PIs) to address ambitious and challenging research questions. Collaborative program teams are expected to be integrated, working together to tackle a single focused scientific goal that requires considerable synergy and meaningful team interaction. Program goals should not be achievable through individual efforts or a collection of projects. Teams are encouraged to consider far-reaching objectives that will produce major advances in their fields.

The National Institutes of Health (NIH) Research Education Program supports research education activities in the mission areas of the NIH. The overarching goal of the Research Education program is to:Support educational activities that complement and/or enhance training of a workforce to meet the nation's biomedical, behavioral and clinical research needs;Help recruit individuals with specific specialty or disciplinary backgrounds to research careers in biomedical, behavioral and clinical sciences; and Foster a better understanding of biomedical, behavioral and clinical research and its implications.

The purpose of this Notice of Funding Announcement (NOFO) is to encourage innovative research that will inform and support the delivery of high-quality, continuously improving mental health services to benefit the greatest number of individuals with, or at risk for developing, a mental illness. This announcement invites applications for non-clinical trial R01-level projects that address NIMH strategic priorities for mental health services research.

The purpose of this announcement is to encourage investigators to pursue translational activities and clinical feasibility studies to advance the development of therapeutic, and diagnostic devices for disorders that affect the nervous or neuromuscular systems. Activities supported in this program include implementation of clinical prototype devices, non-clinical safety and efficacy testing, design verification and validation activities, obtaining an Investigational Device Exemption (IDE) for a Significant Risk (SR) study or Institutional Review Board (IRB) approval for a Non-Significant Risk (NSR) study, as well as a subsequent clinical feasibility study. The clinical study is expected to provide information about the device function or final design that cannot be practically obtained through additional non-clinical assessments (e.g., bench top or animal studies) due to the novelty of the device or its intended use. This FOA is a milestone-driven cooperative agreement program and will involve participation of NIH program staff in negotiating the final project plan before award and monitoring of research progress. Participants in Blueprint MedTech receive funding for all activities to be conducted in their own laboratories. In addition, applicants will collaborate with NIH-funded consultants to receive assistance with specialty areas including regulatory, reimbursement, intellectual property, commercialization, and strategic partnerships. Participants can also augment their project with NIH contract research organizations that specialize in large animal testing, sterilization testing, biocompatibility assessment, manufacturing, and medical monitoring. Individuals, institutions, or businesses developing their own devices or that already have established collaborations with device manufacturers are welcome to apply directly to this NOFO or any of the companion opportunities. For more information see BP MedTech website.

The purpose of the Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32) is to support research training of highly promising postdoctoral candidates who have the potential to become productive, independent investigators in scientific health-related research fields relevant to the missions of the participating NIH Institutes and Centers. Applications are expected to incorporate exceptional mentorship.

The goal of the Institutional Biomedical Undergraduate Research Training (BURT) program is to strengthen research training environments and develop a pool of well-trained students who:Complete their baccalaureate degrees in biomedically-related fields, andTransition into and complete biomedical, research-focused higher degree programs (such as Ph.D. or M.D./Ph.D.).Specifically, this funding announcement provides support to eligible, domestic organizations to develop and implement effective, evidence-informed approaches to biomedical undergraduate training and mentoring to help build a strong biomedical research workforce for the nation.Applicant organizations must enroll undergraduate students and have received NIH Research Project Grant (RPG) funding averaging less than $50 million in total costs (direct and F&A/indirect) per year over the last three fiscal years (FY). To promote undergraduate research training opportunities across a range of eligible organizations, the program will accept applications in two tracks:Single Site: To support trainees from a single baccalaureate-degree granting organization.Community College Partnerships: To support community college trainee development through strong collaborations between at least one associate-degree granting organization (that is, a community college) and at least one baccalaureate-degree granting organization.The proposed research training programs will incorporate didactic, research, and career development elements to prepare trainees for careers that will have a significant impact on the health-related research needs of the nation.

This Notice of Funding Opportunity (NOFO) will support students at institutions without NIH-funded institutional predoctoral dual-degree training programs. The purpose of the Kirschstein-NRSA, dual-doctoral degree, predoctoral fellowship (F30) is to enhance the integrated research and clinical training of promising predoctoral students, who are matriculated in a combined MD/PhD or other dual-doctoral degree training program (e.g. DO/PhD, DDS/PhD, AuD/PhD, DVM/PhD), and who intend careers as physician/clinician-scientists. Candidates must propose an integrated research and clinical training plan and a dissertation research project in scientific health-related fields relevant to the missions of the participating NIH Institutes and Centers. The fellowship experience is expected to clearly enhance the individual's potential to develop into a productive, independent physician/clinician-scientist. This NOFO is designed specifically for candidates proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or an ancillary clinical trial, but does allow candidates to propose research experience in a clinical trial led by a sponsor or co-sponsor.

Rapid advances in genotyping and next generation sequencing technologies have led to the identification of genetic variants that are associated with a wide variety of congenital defects including human congenital anomalies (HCAs), intellectual developmental disabilities (IDDs) and inborn errors of metabolism (IEMs). Large quantities of genomic data collected from pediatric congenital anomalies cohorts are available to the research community through several databases such as the Database of Genotypes and Phenotypes (dbGaP), the Gabriella Miller Kids First Data Resource Portal, the European Genome-Phenome Archive and Clinical Genome Resource (ClinGen). The purpose of this initiative is to promote the screening, functional validation and characterization of congenital anomaly-associated genetic variants identified through public facing databases and individual efforts using in-silico tools, appropriate animal models, in vitro systems or multi-pronged approaches. This initiative addresses a challenging gap between identifying sequence variations of potential interest and recognizing which of those variations have functional effects on the phenotype of interest.

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this NIH Science Education Partnership Award (SEPA) program is to support educational activities that increase understanding of biomedical research among pre-college (pre-kindergarten to grade12) individuals, and to encourage awareness of and continued interest in careers in science, technology, engineering, and mathematics (STEM).

The National Institutes of Health (NIH) Research Education Program supports research education activities in the mission areas of the NIH. The overarching goal of the Research Education program is to:Support educational activities that complement and/or enhance training of a workforce to meet the nation's biomedical, behavioral and clinical research needs;Help recruit individuals with specific specialty or disciplinary backgrounds to research careers in biomedical, behavioral and clinical sciences; andFoster a better understanding of biomedical, behavioral and clinical research and its implications.

The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. The purpose of this Notice of Funding Opportunity (NOFO) encourages Exploratory/Developmental Phased Innovation (R61/R33) grant applications to support development of clinical trials to treat critical and co-occurring health conditions in individuals with Down syndrome. The proposed research aims should be milestone-driven. The total project period for an application submitted in response to this NOFO may not exceed five years. This NOFO provides support for up to two years (R61 phase) for preliminary/developmental/planning studies, followed by possible transition to clinical trial support (R33) of up to three years, although the total duration of the award may not exceed five years. This NOFO requires measurable R61 milestones.

The Economics program supports research designed to improve the understanding of the processes and institutions of the U.S. economy and of the world system of which it is a part. This program also strengthens both empirical and theoretical economic analysis as well as the methods for rigorous research on economic behavior. It supports research in almost every area of economics, including econometrics, economic history, environmental economics, finance, industrial organization, international economics, labor economics, macroeconomics, mathematical economics, and public finance. The Economics program welcomes proposals for individual or multi-investigator research projects, doctoral dissertation improvement awards, conferences, symposia, experimental research, data collection and dissemination, computer equipment and other instrumentation, and research experience for undergraduates. The program places a high priority on interdisciplinary research. Investigators are encouraged to submit proposals of joint interest to the Economics Program and other NSF programs and NSF initiative areas. The program places a high priority on broadening participation and encourages proposals from groups and regions that traditionally have not participated fully in science, mathematics, and engineering. The program also funds conferences and interdisciplinary research that strengthens links among economics and the other social and behavioral sciences as well as mathematics and statistics. The Doctoral Dissertation Research Improvement Grants (DDRIG) funding opportunity is designed to improve the quality of dissertation research. DDRIG proposals are submitted by a faculty member on behalf of the graduate student. DDRIG awards provide funds for items not normally available through the student's university such as enabling doctoral students to undertake significant data-gathering projects and to conduct field research in settings away from their campus. DDRIGs do not provide cost-of-living or other stipends or tuition. Outstanding DDRIG proposals specify how the knowledge to be created advances economics science.  Proposals for Doctoral Dissertation Research Improvement Grants (DDRIGS) in Economics should follow the directions for submissions in the PAPPG . Please contact an Economics program officer if you plan to submit a DDRIG proposal.   For additional funding opportunities, we invite you to also look at the  SBE Office of Multidisciplinary Activities web site .

ATTENTION: This announcement will be revised regularly to incorporate country specific narratives (Attachment 1 of the announcement) with information vital to the content of application. Potential applicants interested in applying to this announcement should click 'Subscribe' to be notified of future revisions.    DoD HIV/AID Prevention Program's (DHAPP) objective, through the PEPFAR program, is to save lives, prevent HIV infections, and accelerate progress toward achieving HIV/AIDS epidemic control and to support the development of interventions and programs in military health systems that address these issues. DHAPP works with militaries of foreign countries to devise plans based on the following process: Meet with key partners in country to determine provisional major program areas and other technical assistance needs. Adapt DHAPP support to a country’s need for prevention, care and/or treatment of its HIV/AIDS situation based on an assessment of the country’s epidemic, and more specifically, in that country’s military. Strengthen the military capacity for ownership and behavioral changes over the long term. Consider program design by leveraging assets with other country partners who have/had successful prevention, care, and/or treatment efforts. Focus on prevention, care and/or treatment impact aligned with national implementation plans. Implement and monitor programs to ensure accountability and sustainability. Countries and their militaries need strong evidenced based HIV programs with measurable courses of action that demonstrate the following specific attributes. Priorities for DHAPP include the following but are subject to change. Support and ownership from the military sector. Development of plans of action and support for military policies that further HIV epidemic control. Alignment with PEPFAR and national strategies and priorities. Testing and treatment expansion to meet 2020 goals of 90-90-90 and 2030 goals of 95-95-95 for people living with HIV. (The first goal is identifying 90/95 percent of all HIV-positive individuals in the population; the second goal is linking 90/95 percent of all those identified HIV positive people to consistent antiretroviral treatment; and the last goal is reaching 90/95 percent of all those on antiretroviral treatment to attain viral suppression.) Care and treatment plans should use the “Treat All” approach with differentiated models of care including tuberculosis (TB), hepatitis, cervical cancer in HIV positive women, other sexually transmitted infections (STI) other opportunistic infections, and care for those with advanced HIV disease. Reduction of mother-to-child transmission of HIV. Combination prevention using biomedical, behavioral and structural support for sexual transmission of HIV and other STI. Prevention packages for specific populations including a comprehensive package for Key Populations (KP), Priority Populations, and prevention interventions for young people. Stigma and discrimination reduction associated with HIV infection. Program monitoring to collect and report on PEPFAR indicators, ensure quality of service delivery using clinical and laboratory monitoring tools and to take rapid corrective action based on results. Strengthen HIV data collection systems for improved clinical decision making and program management. Promoting sustainability through capacity building of the military partner. Transition to Local Partners: Local partners are encouraged to apply to this announcement . To sustain epidemic control, it is critical that the full range of HIV prevention and treatment services are owned and operated by local institutions, governments, and community-based and community-led organizations – regardless of current antiretroviral (ARV) coverage levels. The intent of the transitioning to local partners is to increase the delivery of direct HIV services, along with non-direct services provided at the site, and establish sufficient capacity, capability, and durability of these local partners to ensure successful, long-term, local partner engagement and impact.

Organizations -- private and public, established and entrepreneurial, designed and emergent, formal and informal, profit and nonprofit -- are critical to the well-being of nations and their citizens. They are of crucial importance for producing goods and services, creating value, providing jobs, and achieving social goals. The Science of Organizations (SoO) program funds basic research that yields a scientific evidence base for improving the design and emergence, development and deployment, and management and ultimate effectiveness of organizations of all kinds. SoO funds research that advances our fundamental understanding of how organizations develop, form and operate. Successful SoO research proposals use scientific methods to develop and refine theories, to empirically test theories and frameworks, and to develop new measures and methods. Funded research is aimed at yielding generalizable insights that are of value to the business practitioner, policy-maker and research communities. SoO welcomes any and all rigorous, scientific approaches that illuminate aspects of organizations as systems of coordination, management and governance.  In considering whether a particular project might be a candidate for consideration by SoO, please note: Intellectual perspectives may involve (but are not limited to) organizational theory, behavior, sociology or economics, business policy and strategy, communication sciences, entrepreneurship, human resource management, information sciences , managerial and organizational cognition, operations management, public administration, social or industrial psychology, and technology and innovation management. Phenomena studied may include (but are not limited to) structures, routines, effectiveness, competitiveness, innovation, dynamics, change and evolution. Levels of analysis may include (but are not limited to) organizational, cross-organizational collaborations or relationships, and institutional and can address individuals, groups or teams. Research methods may be qualitative and quantitative and may include (but are not limited to) archival analyses, surveys, simulation studies, experiments, comparative case studies, and network analyses.  Consistent with NSF merit review criteria, each SoO proposal should discuss both the intellectual merit and the potential broader impacts of the proposed research. SoO values basic research that has the potential to provide broader societal benefits. However, the majority of space in any proposal will need to be dedicated to the explication of theory, methods, and specific contribution to the evidence base about organizational effectiveness. Projects that aim to implement and subsequently evaluate particular organizational training, effectiveness or change programs, rather than to advance fundamental, generalizable knowledge, are not appropriate for SoO. Researchers who seek to conduct SoO-appropriate research in an industrial site and/or via an industry-university collaboration are invited to also look at the Grant Opportunities for Academic Liaisons with Industry (GOALI) program web site .

The Sociology Program supports basic research on all forms of human social organization  — societies, institutions, groups and demography  — and processes of individual and institutional change. The program encourages theoretically focused empirical investigations aimed at improving the explanation of fundamental social processes. This includes research on organizations and organizational behavior, population dynamics, social movements, social groups, labor force participation, stratification and mobility, family, social networks, socialization, and the sociology of science and technology. The program supports both original data collection and secondary data analysis that use the full range of quantitative and qualitative methodological tools. Theoretically grounded projects that offer methodological innovations and improvements for data collection and analysis are also welcomed.  Principal Investigators should select PD 98-1331 in the program announcement/solicitation block on the proposal cover sheet for submission of regular research projects to the sociology program. Projects are evaluated using the two foundation-wide criteria, intellectual merit and broader impacts . In assessing the intellectual merit of proposed research, four components are key to securing support from the Sociology Program: (1) the issues investigated must be theoretically grounded; (2) the research should be based on empirical observation or be subject to empirical validation or illustration; (3) the research design must be appropriate to the questions asked; and (4) the proposed research must advance our understanding of social processes, structures and methods. NSF also offers a number of specialized funding opportunities through its crosscutting and cross-directorate activities; some of the sociology-related opportunities are listed below. Crosscutting Research & Training Opportunities: ADVANCE: Increasing the Participation and Advancement of Women in Academic Science and Engineering Careers Faculty Early Career Development (CAREER) Program Graduate Research Fellowship Program (GRFP) Major Research Instrumentation (MRI) Program Mid-scale Research Infrastructure Programs SBE Postdoctoral Research Fellowships (SPRF) Research Experiences for Undergraduates (REU) Research at Undergraduate Institutions (RUI) Small Business Innovation Research (SBIR) Program To get information about these programs and others, please visit the  cross-cutting and NSF-wide active funding opportunities  search page. NSF's mission calls for the broadening of opportunities for and expanding participation of groups, institutions and geographic regions that are underrepresented in STEM disciplines, which is essential to the health and vitality of science and engineering. NSF is committed to this principle of diversity and deems it central to the programs, projects and activities it considers and supports.  NSF is also committed to public access to publications and data, unless there are countervailing interests that prohibit or limit public access to data, including matters of personally identifiable information of research participants, privacy or other issues of vulnerability such as economic, social or other security interests, etc.). See  Public Access to Results of NSF-Funded Research  and  Data Management for NSF SBE Directorate Proposals and Awards for more information.

NSF GRANTED supports innovative models of research enterprise administrative development and workforce training infrastructure that promote sustainable research capacity and opportunities for economic impact in U.S. organizations. The research enterprise, broadly defined, includes research development and administration, research analytics, technology transfer and commercialization, corporate relations/public-private partnerships, research integrity, compliance and security, research policy, administration of student research training, and research leadership. Strengthening and transforming this administrative infrastructure is necessary to fully utilize the Nation's research talent and capabilities and empower America's organizations that engage in or support research and its outcomes, to participate in a globally competitive research enterprise. Program Description Maintaining U.S. global leadership demands a research enterprise that is competitive, effective, sustainable a nd contributes to the Nation's economic growth goals. A strong national research enterprise relies on more than funding for the research itself. It also requires robust administrative support-and-service infrastructure, which is often unseen, yet includes critical components to ensure a competitive research environment regardless of organization or location. Research enterprise infrastructure enables the development of proposals and management of awards and supports research translation through technology transfer and public-private partnerships. Research compliance enables the security and integrity of research approaches. Research analytics and communication, managing the training of the U.S. scientific workforce, and harnessing the creativity and drive of research leadership, and more, are also fundamental components of the infrastructure. The  GRANTED initiative  provides unique opportunities to realize a broad and collaborative vision for research enterprise infrastructure. Proposals in response to this GRANTED program description should engage the professional, administrative research support-and-service workforce in project leadership roles described within proposals. Proposed projects should look beyond individual and discipline-specific research needs and focus on activities that create organization-wide impact and potential for regional and national impact. Projects should propose scalable approaches and models to build and sustain research enterprise infrastructure. Competitive proposals will recognize structural and organizational challenges and include goals to implement interventions, solutions, and/or strategies that will mitigate the challenges. Proposals must be centered around one or more of the three main themes of GRANTED: Innovating and enhancing practices and processes within the research enterprise; Developing and strengthening human capital within the research enterprise; and Translating effective practices related to the research enterprise into a broad range of organizational contexts. The GRANTED program utilizes general proposal requirements, including eligibility, as outlined in the current NSF Proposal and Award Policies and Procedures Guide (PAPPG). Prospective PIs are strongly encouraged to contact GRANTED initiative personnel ( GRANTED@nsf.gov ) with inquiries prior to developing and submitting a proposal to this program description. The project budget and duration should be determined by the scope of the proposed activities and presented in accordance with the PAPPG. GRANTED is not intended to fund discipline-specific STEM research and training projects. Collectively, proposals funded through this Program Description will advance transformation of the national research enterprise, measured through 1) generating scalable models that improve research capacity and competitiveness, 2) creating collaborations, partnerships, and communities centered around strengthening the Nation's research enterprise, 3) increasing the range of project leadership, organizations, ideas, and approaches that NSF funds, especially related to developing areas aligned to agency priorities, and 4) strengthening engagement across the Nation’s research enterprise.

The Accountable Institutions and Behavior (AIB) Program supports basic scientific research that advances knowledge and understanding of issues broadly related to attitudes, behavior, and institutions connected to public policy and the provision of public services. Research proposals are expected to be theoretically motivated, conceptually precise, methodologically rigorous, and empirically oriented. Substantive areas include (but are not limited to) the study of individual and group decision-making, political institutions (appointed or elected), attitude and preference formation and expression, electoral processes and voting, public administration, and public policy. This work can focus on a single case or can be done in a comparative context, either over time or cross-sectionally. The Program does not fund applied research. The Program also supports research experiences for undergraduate students and infrastructural activities, including methodological innovations. In addition, we encourage you to examine the websites for the National Science Foundation’s Law and Science (LS) ,   Security and Preparedness (SAP) and Research Infrastructure in the Social and Behavioral Sciences (RISBS) programs.

The Science of Science:Discovery, Communication and Impact (SoS:DCI) program is designed to advance theory and knowledge about increasing the public value of scientific activity. Science of Science draws from multiple disciplinary and field perspectives to advance theory and research about scientific discovery, communication and impact. SoS:DCI welcomes proposals applying rigorous empirical research methods to advance theory and knowledge on: The social and structural mechanisms of scientific discovery. Theories, frameworks, models and data that improve our understanding of scientific communication and outcomes. The societal benefits of scientific activity and how science advances evidence-based policy making and the creation of public value. The SoS:DCI program, which expands upon the formerScience of Science and Innovation Policy (SciSIP)program, funds research that builds theoretical and empirical understanding of the social science of science. SoS:DCI welcomes proposals to conduct research at the individual, organizational and institutional levels or from micro, meso and macro scales and complex system levels. SoS:DCI encourages multiple disciplinary perspectives, interdisciplinary research and diverse methodological approaches in the pursuit of new knowledge to advance the science of science and evidence-based policy making. With these goals in mind, proposals should: Draw from and advance theory, knowledge and frameworks on the science of science. Develop models, data, indicators and associated analytical tools that constitute and enable transformative advances rather than incremental change. Provide credible rigorous assessments of the proposed project’s impact and social and policy implications. Include robust data management plans with the goal of advancing open science and increasing public access to usable, valid and reliable scientific materials. Of particular interest are proposals with the potential to strengthen America’s global leadership in science and increase national competitiveness across a broad range of domains. These include proposals that analyze strategies for strengthening and expanding the scientific workforce, as well as ways to cultivate high-impact discovery across sectors.The program strongly encourages convergent research and collaboration. In addition to intellectual merit, the program strongly encourages potential PIs to carefully consider the broader impacts of their work. The broader impacts criterion encompasses the potential to benefit society and contribute to the achievement of specific, desired policy outcomes.The Social, Behavioral and Economic Sciences Directorate has released additional guidance on broader impacts for SBE proposals . The SoS:DCI program places a high priority on broadening participation in the sciences. It encourages proposals from early-career researchers and from researchers who represent groups and regions that have historically participated at disproportionately low rates in science, mathematics, and engineering. SoS:DCI supports the following types of proposals: Standard Research Grants and Grants for Collaborative Research A Science of Science Approach to Analyzing and Innovating the Biomedical Research Enterprise (SoS:BIO) Conference Grants SoS:DCI also participates in certain specialized funding opportunities through NSF’s cross-cutting and cross-directorate activities .

Large-scale simulations and the ability to accumulate massive amounts of data have revolutionized science and engineering. The goal of the Computational and Data-enabled Science and Engineering (CDS&E) meta-program is to identify and capitalize on opportunities for major scientific and engineering breakthroughs through new computational and data-analysis approaches and best practices. The CDS&E meta-program supports projects that harness computation and data to advance knowledge and accelerate discovery above and beyond the goals of the participating individual programs. The intellectual drivers may be in an individual discipline or cut across more than one discipline in various Divisions and Directorates. A CDS&E proposal should enable and/or utilize the development and adaptation of advances in research and infrastructure in computational and data science. The CDS&E meta-program encourages research that pushes the envelope of science and engineering through computation and data, welcoming proposals in any research area supported by the participating divisions. A proposal may address topics that develop or enable interactions among theory, computing, experiment, and observation to achieve progress on hitherto intractable science and engineering problems. Areas of emphasis for CDS&E vary by program. PIs are advised to consult the "related programs" links below before submitting. The CDS&E meta-program is not intended to replace existing programs that support projects involving computation or the analysis of large or complex data sets using established methods. Rather, proposals submitted to the CDS&E meta-program must have a significant component of computational or data science that goes well beyond what would typically be included in these programs.Any proposal submitted to the CDS&E program that is not responsive to this Program Description may be transferred to or reviewed within the context of an individual program. A proposal requesting consideration within the context of CDS&E should begin the title with the identifying acronym "CDS&E:". Supplement requests to existing awards may also be considered. A CDS&E proposal should include substantive science, engineering, or computing research. Algorithm and pilot software development supporting science and engineering may also be appropriate, depending on the program. Proposers who seek to implement proven, existing methods into robust cyberinfrastructure are referred instead to the program on Cyberinfrastructure for Sustained Scientific Innovation (CSSI). A CDS&E proposal should be submitted to one of the "Related Programs" or Divisions by the associated submission window, deadline, or target date listed in the table below. In picking the most relevant program, PIs are advised to read program descriptions and solicitations carefully and consult with cognizant Program Officers before proposal preparation. Proposal submissions outside the receiving program's scientific scope may be transferred to a different program or returned without review. Due Dates Directorate Division and Program Submission Window or Target Date ENG Division of Chemical, Bioengineering, Environmental, and Transport Systems September 01, 2024 - September 16, 2024 September 01- September 15, Annually Thereafter ENG Division of Civil, Mechanical and Manufacturing Innovation September 01, 2024 - September 16, 2024 September 01- September 15, Annually Thereafter MPS Division of Chemistry - Chemical Catalysis (CAT), Chemical Mechanism, Function, and Properties (CMFP), Chemical Synthesis (SYN) September 01, 2024 - September 30, 2024 September 01 - September 30, Annually Thereafter MPS Division of Materials Research October 15, 2024 October 15, Annually Thereafter MPS Division of Astronomical Sciences - Advanced Technologies and Instrumentation October 01, 2024 - November 15, 2024 October 01 - November 15, Annually Thereafter MPS Division of Chemistry - Chemical Measurement and Imaging (CMI), Environmental Chemical Sciences (ECS), and Macromolecular, Supramolecular and Nanochemistry (MSN) October 01, 2024 - October 31, 2024 October 1 - October 31, Annually Thereafter MPS Division of Mathematical Sciences October 15, 2024 - October 31, 2024 October 15 - October 31, Annually Thereafter MPS Division of Astronomical Sciences - Astronomy and Astrophysics Research Grants October 01, 2024 - November 15, 2024 October 01 - November 15, Annually Thereafter MPS Division of Physics: Investigator-Initiated Research Projects – Plasma Physics program November 20, 2024, Third Monday in November, Annually Thereafter MPS Division of Chemistry - Chemistry of Life Processes (CLP), Chemical Structure and Dynamics (CSD), Chemical Theory, Models and Computational Methods (CTMC) Full proposals accepted anytime

The Biosensing program is part of the Engineering Biology and Health cluster, which also includes 1) the Biophotonics program; 2) the Cellular and Biochemical Engineering program; 3) the Disability and Rehabilitation Engineering program; and 4) the Engineering of Biomedical Systems program. The Biosensing program supports fundamental engineering research in the monitoring, identification and/or quantification of biological analytes and phenomena using innovations that exist at the intersection of engineering, life sciences, and information technology. Projects submitted to the program must advance both engineering and life sciences. The Biosensing program encourages proposals that, in addition to advancing biosensing technology, address critical sensor needs in biomedical research, public health, food safety, agriculture, forensics, environmental protection, and homeland security. Proposals are especially encouraged in areas of critical need: sensing technologies that can enable monitoring and surveillance of the environment and/or individuals for novel infectious agents; platform technologies that can readily be modified as soon as new agents are detected, sequenced, and/or otherwise characterized to enable rapid deployment of sensors in clinics and the environment; and adaptive and/or multiplex sensing technologies that can help the nation prevent the spread of the next global pandemic. Major areas of interest for the program include: Novel signal transduction principles and mechanisms that enable sensitive and specific biosensors, suitable for measurements in multiple areas; Design of novel biorecognition elements and appropriately designed transducing systems to enable adaptable and/or reconfigurable operating parameters in response to environmental changes or application needs at levels of device, system, or data analysis; Development of adaptive and/or evolvable biosensing systems for detection of novel target analytes or analytes under novel conditions; Novel synthetic biology approaches for the development of cell-free and cell-based biosensors; and Combining biosensors with artificial intelligence (AI) methods to improve sensor specificity and response time. Innovative ideas outside of the above specific interest areas may be considered. However, prior to submission, it is recommended that the PI contact the program director to avoid the possibility of the proposal being returned without review. The Biosensors program does not encourage proposals addressing circuit design for signal processing and amplification, computational modeling, and microfluidics for sample separation and filtration. Medical imaging-based measurements are outside of the scope of the program interests. Proposals that rely heavily on descriptive approaches are given lower priority. Proposals for optimizing and/or utilizing established methods for specific applications should be directed to programs focused on the application of sensor technology. NOTE: Projects related to water and/or soil quality may be jointly supported with the Environmental Engineering program (CBET 1440). Photonic devices with medical imaging and/or optogenetics should be submitted to the Biophotonics program (CBET 7236). Applications of devices for tissue engineering or organ-on-chip systems should be submitted to the Engineering of Biomedical Systems program (CBET 5345). Basic chemical/biochemical sensing mechanisms should be submitted to the Chemical Measurement and Imaging program (CMI 6880) in the Division of Chemistry. Proposals for dynamic biosensing systems, including circuit design for signal/data processing and amplification, and sensing systems through communication and machine learning should be submitted to the Communications, Circuits, and Sensing-Systems program (CCSS 7564) in the Division of Electrical, Communications, and Cyber Systems. INFORMATION COMMON TO MOST CBET PROGRAMS Proposals should address the novelty and/or potentially transformative nature of the proposed work compared to previous work in the field.Also, it is important to address why the proposed work is important in terms of engineering science, as well as to also project the potential impact on society and/or industry of success in the research.The novelty or potentially transformative nature of the research should be included, as a minimum, in the Project Summary of each proposal. The duration of unsolicited proposal awards in CBET is generally up to three years. Single-investigator award budgets typically include support for one graduate student (or equivalent) and up to one month of PI time per year(awards for multiple investigator projects are typically larger). Proposal budgets that are much larger than typical should be discussed with the program director prior to submission. Proposers can view budget amounts and other information from recent awards made by this program via the ?What Has Been Funded (Recent Awards Made Through This Program, with Abstracts)? link towards the bottom of this page. Faculty Early Career Development(CAREER)program proposals are strongly encouraged.Award duration is five years.The submission deadline for Engineering CAREER proposals is in July every year. Learn more in the CAREER program description . Proposals for Conferences, Workshops, and Supplements: PIs are strongly encouraged to discuss their requests with the program director before submission of the proposal. Grants forRapid Response Research(RAPID)andEArly-concept Grants for Exploratory Research(EAGER)are also considered when appropriate. Please note that proposals of these types must be discussed with the program director before submission. Grant Opportunities for Academic Liaison with Industry (GOALI)proposals that integrate fundamental research with translational results and are consistent with the application areas of interest to each program are also encouraged. Please note that RAPID, EAGER, and GOALI proposals can be submitted anytime during the year. Details about RAPID, EAGER, and GOALI are available in the Proposal & Award Policies & Procedures Guide(PAPPG), Part 1, Chapter II, Section E: Types of Proposals. Compliance: Proposals that are not compliant with the Proposal & Award Policies & Procedures Guide (PAPPG) will be returned without review.

The Accountable Institutions and Behavior (AIB) Program supports basicscientific research that advances knowledge and understanding of issues broadly related to attitudes, behavior, and institutions connected to public policy and the provision of public services.Research proposals are expected to be theoretically motivated, conceptually precise, methodologically rigorous, and empirically oriented. Substantive areas include (but are not limited to) the study of individual and group decision-making, political institutions (appointed or elected), attitude and preference formation and expression, electoral processes and voting, public administration, and public policy. This work can focus on a single case or can be done in a comparative context, either over time or cross-sectionally.The Program does not fund applied research.The Program also supports research experiences for undergraduate students and infrastructural activities, including methodological innovations. In addition, we encourage you to examine the websites for the National Science Foundation’s Law and Science(LS), Security and Preparedness (SAP) and Research Infrastructure in the Social and Behavioral Sciences (RISBS) programs.

Organizations -- private and public, established and entrepreneurial, designed and emergent, formal and informal, profit and nonprofit -- are critical to the well-being of nations and their citizens. They are of crucial importance for producing goods and services, creating value, providing jobs, and achieving social goals. The Science of Organizations (SoO) program funds basic research that yields a scientific evidence base for improving the design and emergence, development and deployment, and management and ultimate effectiveness of organizations of all kinds. SoO funds research that advances our fundamental understanding of how organizations develop, form and operate. Successful SoO research proposals use scientific methods to develop and refine theories, to empirically test theories and frameworks, and to develop new measures and methods. Funded research is aimed at yielding generalizable insights that are of value to the business practitioner, policy-maker and research communities. SoO welcomes any and all rigorous, scientific approaches that illuminate aspects of organizations as systems of coordination, management and governance. In considering whether a particular project might be a candidate for consideration by SoO, please note: Intellectual perspectives may involve (but are not limited to) organizational theory, behavior, sociology or economics, business policy and strategy, communication sciences, entrepreneurship, human resource management, information sciences, managerial and organizational cognition, operations management, public administration, social or industrial psychology, and technology and innovation management. Phenomena studied may include (but are not limited to) structures, routines, effectiveness, competitiveness, innovation, dynamics, change and evolution. Levels of analysis may include (but are not limited to) organizational, cross-organizational collaborations or relationships, and institutional and can address individuals, groups or teams. Research methods may be qualitative and quantitative and may include (but are not limited to) archival analyses, surveys, simulation studies, experiments, comparative case studies, and network analyses. Consistent with NSF merit review criteria, each SoO proposal should discuss both the intellectual merit and the potential broader impacts of the proposed research. SoO values basic research that has the potential to provide broader societal benefits. However, the majority of space in any proposal will need to be dedicated to the explication of theory, methods, and specific contribution to the evidence base about organizational effectiveness. Projects that aim to implement and subsequently evaluate particular organizational training, effectiveness or change programs, rather than to advance fundamental, generalizable knowledge, are not appropriate for SoO. Researchers who seek to conduct SoO-appropriate research in an industrial site and/or via an industry-university collaboration are invited to also look at the Grant Opportunities for Academic Liaisons with Industry (GOALI) program web site .

NSF GRANTED supports innovative models of research enterprise administrative development and workforce training infrastructure that promote sustainable research capacity and opportunities for economic impactin U.S. organizations. The research enterprise, broadly defined, includes research development and administration, research analytics, technology transfer and commercialization, corporate relations/public-private partnerships, research integrity, compliance and security, research policy, administration of student research training, and research leadership. Strengthening and transforming this administrative infrastructure is necessary to fully utilize the Nation's research talent and capabilities and empower America's organizations that engage in or support research and its outcomes, to participate in a globally competitive research enterprise. Program Description Maintaining U.S. global leadership demands a research enterprise that is competitive, effective, sustainable a nd contributes to the Nation's economic growth goals. A strong national research enterprise relies on more than funding for the research itself. It also requires robust administrative support-and-service infrastructure, which is often unseen, yet includes critical components to ensure a competitive research environment regardless of organization or location. Research enterprise infrastructure enables the development of proposals and management of awards and supports research translation through technology transfer and public-private partnerships. Research compliance enables the security and integrity of research approaches. Research analytics and communication, managing the training of the U.S. scientific workforce, and harnessing the creativity and drive of research leadership, and more, are also fundamental components of the infrastructure. The GRANTED initiative provides unique opportunities to realize a broad and collaborative vision for research enterprise infrastructure. Proposals in response to this GRANTED program description should engage the professional, administrative research support-and-service workforce in project leadership roles described within proposals.Proposed projects should look beyond individual and discipline-specific research needs and focus on activities that create organization-wide impact and potential for regional and national impact. Projects should propose scalable approaches and models to build and sustain research enterprise infrastructure.Competitive proposals will recognize structural and organizational challenges and include goals to implement interventions, solutions, and/or strategies that will mitigate the challenges. Proposals must be centered around one or more of the three main themes of GRANTED: Innovating and enhancing practices and processes within the research enterprise; Developing and strengthening human capital within the research enterprise; and Translating effective practices related to the research enterprise into a broad range of organizational contexts. The GRANTED program utilizes general proposal requirements, including eligibility, as outlined in the current NSF Proposal and Award Policies and Procedures Guide (PAPPG). Prospective PIs are strongly encouraged to contact GRANTED initiative personnel ( GRANTED@nsf.gov ) with inquiries prior to developing and submitting a proposal to this program description. The project budget and duration should be determined by the scope of the proposed activities and presented in accordance with the PAPPG.GRANTED is not intended to fund discipline-specific STEM research and training projects. Collectively, proposals funded through this Program Description will advance transformation of the national research enterprise, measured through 1) generating scalable models that improve research capacity and competitiveness, 2) creating collaborations, partnerships, and communities centered around strengthening the Nation's research enterprise, 3) increasing the range of project leadership, organizations, ideas, and approaches that NSF funds, especially related to developing areas aligned to agency priorities, and 4) strengthening engagement across the Nation’s research enterprise.

Many of the most pressing challenges in research and innovation require collaboration across national and disciplinary boundaries to achieve important advances. A growing number of topics are best addressed on a multilateral basis, building partnerships that leverage diverse expertise, data, infrastructure, and perspectives to advance understanding on critical topics of regional or global importance. At the same time, funders, research organizations, and researchers alike typically have limited experience with multilateral partnerships. The Office of International Science and Engineering’s MultiPLEx program seeks to support visionary, and ambitious international multilateral research partnerships that are required to hasten progress in addressing grand challenges by leveraging research excellence in the U.S. and around the globe. The program also seeks to advance understanding of effective multilateral collaboration. MultiPLEx welcomes proposals that Address urgent research and/or societal challenge of global importance (including but not limited to critical and emerging technology research) and require an inherently international multilateral approach to achieve impactful research results, partnering with at least two countries other than the U.S. Proposals that engage partners across distinct geographic regions are an area of interest. Make clear how the proposed international collaboration will enable research advances and broader impacts that go beyond what can be accomplished by a narrower team. Include a diverse group of U.S. institutions and/or individuals, leveraging the full range of talent that society has to offer MultiPLEx funds support the U.S. research team. Research partners should seek funding from their own national funding agencies or from other sources. A typical MultiPLEx award will be up to three years in duration. The MultiPLEX program is not intended to replace existing OISE or directorate programs. Proposals submitted to MultiPLEX must fall outside the scope of existing OISE or directorate programs. Any proposal submitted to MultiPLEx that is not responsive to this Program Description may be transferred to another OISE program or returned without review. OISE may periodically issue a Dear Colleague Letter inviting MultiPLEx proposals in specific priority areas. PIs interested in submitting proposals that do not respond to a DCL are strongly encouraged to consult a MultiPLEx program director prior to submission to confirm appropriateness. Unless specified in a DCL, MultiPLEx proposals may be submitted any time.

Infrastructure systems comprise complex connections between physical components, organizational structures and operational methods that support the needs of people and communities at the local, regional, national, and global scales. Such systems form the backbone of society, providing essential services as well as ensuring public health and welfare, economic prosperity and national security, and are expected to function under all operational conditions. Meanwhile, infrastructure systems are capital intensive and vulnerable to disruptions from extreme events, including natural disasters, social crises, and malicious attacks. Disruptions in one system can have cascading impacts on others in space and over time. Moreover, short- versus long-term trade-offs, unintended consequences, and maladaptation are not often accounted for. How systems function at the “extreme,” which can be due to disruptors from the introduction of innovation, the convergence of technologies, sudden changes to their utilization and access, dramatic changes in operating environments, and changes to demand during crises are of particular interest. To ensure the efficiency, sustainability, resilience, and fair use of infrastructure systems, it is important to continuously improve and optimize their design, operations, system monitoring and performance assessment in dynamic, uncertain and sometime unknown environments. While functioning at extremes is of interest, the program also supports infrastructure systems research under the full range of operating conditions, across a variety of hazards, and in urban, suburban, and rural communities. The program particularly encourages interdisciplinary and multidisciplinary exploration that will open new research frontiers and significantly expand and transform relevant research communities. The program welcomes research that addresses novel system integration, user-inspired system and service design, data analytics, and socio-technical studies focused on engineering and system innovation during normal and extreme conditions. The program also values innovative research efforts focused on collecting, standardizing, and sharing large-scale databases of real-world infrastructure systems and people-infrastructure interactions during normal and extreme operating conditions, which can be instrumental in providing benchmarks for model verification and validation and for advancing future research innovation in ISP. The ISP program supports research on lifeline systems and communities that contributes to the National Science Foundation’s role in the National Earthquake Hazards Reduction Program (NEHRP) and the National Windstorm Impact Reduction Program (NWIRP). Principal Investigators are encouraged to leverage NSF’s investments in the Natural Hazards Engineering Research Infrastructure (NHERI) experimental, computational modeling and simulation, and data resources (https://www.designsafe-ci.org/) in their research to accelerate advances needed for reducing the impacts of natural hazards on infrastructures and people. While physics-based subject-matter knowledge may be crucial in many research efforts, the program does not support research whose primary methodological contribution focuses on individual infrastructure components without a systems research perspective whose primary methodological focus is on geotechnical and structural engineering, material sciences, architectural engineering, wireless communication and sensor technology, human factors, and/or hydrologic or environmental engineering. Proposers are actively encouraged to email a one-page project summary to the ISP Program Officers before submitting a full proposal for guidance on whether the proposed research topic falls within the scope of the ISP program; this guidance should especially be requested for multi-disciplinary research proposals, and proposals for which research and/or development on the subject infrastructure(s) are also supported by other federal and/or state agencies.