Research grants for Researchers

Expected Outcome: This action will establish a strategic European initiative to develop scalable, modular, and interoperable photonic quantum computing platforms. Proposals for this topic are expected to address and provide credible solutions to at least two major technical roadblocks currently limiting the advancement of photonic quantum computing such as: The lack of deterministic, high-efficiency photonic entanglement and loss-tolerant architectures suitable for fault-tolerant scaling The absence of a standardised, integrated control stack combining photonic hardware, firmware, and system software with reliable benchmarking across platforms Project results are expected to contribute to the following expected outcomes: By 2028, demonstration of a photonic NISQ processor with ≥100 photonic qubits, integrating deterministic single-photon sources, low-loss waveguides, on-chip detectors, and a firmware stack (scheduler, controller, compiler), validated via hardware-agnostic benchmarks and hybrid photonic-HPC applications demonstrating classical-quantum crossover By 2030, delivery of a full-stack, high-connectivity photonic quantum computer, with modular scalability, integrated…

Expected Outcome: Excellent capacities in research management are essential for institutions and national R&I systems to enhance their research excellence and capitalize on their R&I activities in a knowledge-based economy and society. The Research Management Facility aims at providing institutions in Widening countries that want to establish or upgrade their research management capacities with tailored support. The Research Management Facility also advises on an implementation strategy to introduce changes in the institutional set-up, in line with the ERA priorities. However, the action does not provide support for the implementation of the strategy. Strong research management ensures effective grant acquisition, resource allocation, compliance with funding regulations, and strategic planning. It supports high-quality research by streamlining administrative processes, facilitating interdisciplinary collaborations, attracting and retaining international high-profile researchers, and optimizing the use of research infrastructures. Proposals are expected to contribute to the following outcomes: Encourage the establishment of stronger research management capacities in Widening…

Expected Outcome: Activities under this topic will help progress towards the objectives and targets of the Mission Soil and the EU Soil Strategy for 2030 . Activities should also contribute to the implementation of the Soil Monitoring and Resilience Directive after its adoption. Project results are expected to contribute to all the following expected outcomes: enhanced adoption of impactful sustainable soil management solutions and strategies supported by AI-powered decision support systems by land managers; harmonised, standard, robust, interoperable and accessible methods, protocols and logical architecture for long-term field experiments (LTEs) data collection and integration (including with other datasets) are in place; scientists, policymakers, and land managers gain enhanced access to comprehensive, high-quality soil data, enabling better research, informed decision-making, and effective land management practices. Scope: Long-term field experiments (LTEs) can be defined as “agricultural experiments for monitoring soil and crop properties under changing climate conditions and different management with a minimum duration of 20 years” [1] , [2] . LTEs are typically owned or…

Expected Outcome: The Synergy action for Teaming Centres of Excellence (CoE) responds to the need to ensure the sustainability of CoE funded under the Teaming calls [1] . The establishment of CoE in Widening countries, supported by a significant investment in Horizon 2020 and Horizon Europe, has created new opportunities for scientific, societal, and economic impact. However, to fully capitalise on this investment and enhance the sustainability and international competitiveness of these CoE, it is essential to facilitate stronger collaboration and strategic joint initiatives among them. Proposals are expected to contribute to all the following outcomes: Stronger long-term collaboration among Teaming CoE through structured joint initiatives and clustering efforts to enhance mutual learning, resource sharing, and collective research and innovation capacity; Strategic transformation of R&I systems by enhancing institutional cooperation and supporting structural reforms at national and regional levels; Promotion of multidisciplinary and transnational cooperation that will enable CoE to address critical European and global challenges, and EU policy priorities; Promote ERA priorities…

Expected Outcome: the project results are expected to contribute to all of the following outcomes: access to cutting-edge infrastructure for researchers and research teams from Euratom and Associated Countries to EU and international state-of-the-art nuclear research infrastructures; enhancing the network developed under the OFFERR project for optimised use of nuclear research infrastructures identified in the EU, thus supporting the implementation of the Euratom programme’s objectives and the establishment of the European Research Area (ERA) in the nuclear safety and radiation protection field; strengthened cross-border collaboration in nuclear safety and radiation protection research in the EU, a significant increase in transnational nuclear research and the fostering of shared expertise and resources; preservation of critical facilities, possibly increasing their number to ensure the long-term availability of key experimental facilities for research into safety, security, safeguards, radioactive waste management and radiation protection (e.g. materials testing research reactors in operation, irradiation infrastructure, hot cells and laboratories, mechanical and thermal…

Treasury is publishing multiple funding opportunity notices for its RESTORE Act grant programs. This announcement applies only to the Centers of Excellence Research Grants Program.Trust Fund amounts are available to establish one or more Centers of Excellence through competitive subawards to nongovernmental entities and consortia in the Gulf Coast Region, including institutions of higher education. Funds may be used to establish Centers of Excellence, and by those Centers of Excellence for science, technology, and monitoring in one or more of the following disciplines as described in the RESTORE Act and Treasury’s implementing regulations at 31 CFR 34.704: 1) Coastal and deltaic sustainability, restoration, and protection, including solutions and technology that allow citizens to live in a safe and sustainable manner in a coastal delta in the Gulf Coast Region. 2) Coastal fisheries and wildlife ecosystem research and monitoring in the Gulf Coast Region. 3) Offshore energy development, including research and technology to improve the sustainable and safe development of energy resources in the Gulf of Mexico. 4) Sustainable and resilient growth, economic and commercial development in the Gulf Coast Region. 5) Comprehensive observation, monitoring, and mapping of the Gulf of Mexico.Eligible applicants issuing subawards to Center(s) of Excellence must establish and implement a program to monitor compliance with its subaward agreements.

Expected Outcome: Expected outcomes: A sustained pipeline of highly qualified semiconductor graduates, with shorter time-to-readiness for industry roles; greater inflow of diverse talent including women and underrepresented groups; improved intra- and extra-EU student mobility; and strong complementarity with existing Chips Act infrastructure such as pilot lines, design platforms, and Competence Centres. Scope: This call funds the creation of specialised academic "Hubs of Excellence" in critical semiconductor technology areas (e.g. chip design, manufacturing, photonics, power electronics). Projects should build industry-aligned Bachelor, Master, and PhD programmes.

Expected Outcome: Proposals are expected to contribute to all following points: Significantly reduced EU dependency on imported battery-grade raw materials, specifically emerging technologies and carbon-based electrode materials. Established European value chains for next-generation battery materials, enhancing the EU's technological leadership and strategic autonomy. Scope: Proposals under this topic are expected to address all aspects for one of the following categories: 1. Sustainable Processing and Refining of next generation batteries-grade Material, delivering all of the following: Development and validation of innovative, environmentally friendly refining technologies for producing battery-grade metals and materials suitable for next-generation battery chemistries. This covers raw and advanced electrode materials for the components of sodium-ion batteries or beyond generation 3 [1] lithium-ion batteries Development of processes achieving significant reductions in carbon and ecological footprint, emissions of pollutants, energy usage, and chemical inputs. The selected processes should not negatively impact any of the aspects above or cause significant harm. Validation of…

Expected Outcome: this topic is a continuation for the co-funded European partnership for research in nuclear materials (CONNECT-NM) and constitutes the EU’s contribution to the 2026-2027 budgetary period. This action aims to provide additional funding to the co-funded European partnership on nuclear materials that brings together European entities that have a national mandate for research in materials science and deal with nuclear materials. It aims to pool their resources in order to achieve critical mass and improve safety, as well as efficiency and effectiveness, when implementing materials solutions in the nuclear domain across Europe. The scope of the partnership on nuclear materials covers the research interests of all Member States and Associated Countries dealing with nuclear materials research. It is not limited to countries that generate nuclear power. The grant to the partnership will contribute to the expected outcomes specified in topic HORIZON-EURATOM-2023-NRT-01-04. The consortium that won the grant under topic HORIZON-EURATOM-2023-NRT-01-04 is uniquely placed to submit a proposal to continue the envisioned partnership. The consortium for the present topic may…

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes: impacts of continuous and impulsive underwater noise levels on marine organisms and ecosystems, and the related ecosystem services they provide, including cumulative impacts with other pressures, are well understood, taking into account regional differences; environmental authorities have access to advanced methods, tools and indicators enabling them to comprehensively monitor and assess the impacts of underwater noise pollution on marine species and ecosystems and to devise strategies for protecting the ecosystems services they provide. Scope: Proposals should: develop new, or improve upon existing, scientific methods and tools for comprehensively monitoring the impacts of anthropogenic underwater noise pollution on marine ecosystems and species populations at different trophic levels and taking into account regional differences; develop new, or improve upon existing, indicators for the assessment of the effects of noise exposure as well as their cumulative effects on marine organisms and ecosystems, and the services they provide, in line with methods (including threshold…

Expected Outcome: Battery recycling is of strategic importance for both Europe and India, not only to keep raw materials in the respective territories but also to reduce the environmental impact of the recycling process. R&I in this area has been identified as a priority by the EU-India Trade and Technology Council’s Working Group on Green and Clean Energy Technology to reinforce bilateral cooperation. Project results are expected to contribute to all of the following expected outcomes: Battery recyclers based in the EU and India benefit from of the improved sustainability, safety, and affordability of innovative recycling processes. Stakeholders on battery recycling based in the EU and India benefit from each other’s experience on recycling logistics, including the informal processes and supply chain constraints. The cooperation between EU and India key researchers, institutions and industries which are active in battery recycling is supported and strengthened. Scope: Projects are expected to build a jointly operated recycling pilot line on Indian soil demonstrating innovative recycling processes for lithium-ion batteries going beyond the current state of the art in terms of…

Expected Outcome: Successful proposals will contribute to the Circular Economy Action Plan, the Chemicals Strategy for Sustainability and the Ecodesign for Sustainable Products Regulation. Projects results are expected to contribute to the following expected outcomes: Wider availability of bio-based films and coatings for packaging products. Improved technical performances of packaging products compared to fossil based and/or bio-based benchmarks. Improved circularity of packaging products against specified market benchmarks taking into account production, use and EoL. Scope: Many research projects have focused on developing and piloting bio-based coatings and films for application in food and non-food packaging. When targeting packaging, a primary challenge is achieving adequate barrier properties (against oxygen, moisture, grease and volatiles), as bio-based materials are typically more hydrophilic than conventional plastics like PE or PET. Processing methods, including bio-based coating deposition, face scalability and reproducibility issues. Coatings must adhere well to substrates while maintaining technical properties and not hindering sustainable EoL. Printability is another…

Expected Outcome: Successful proposals will contribute to the implementation of the EU initiative on Biotechnology and Biomanufacturing and the EU Life Sciences Strategy as well as the updated EU Bioeconomy Strategy, the Clean Industrial Deal, the European Chemical Industry Action Plan, the upcoming EU Biotechnology and Circular Economy Acts. Projects results are expected to contribute to the following expected outcomes: Increased added value of residual biomass for biorefinery applications. Availability of a wider portfolio of sustainable bio-based products via industrial biotech. Robust, scalable and efficient biotech process(es) applicable to residual biomass. Scope: Diversifying biomass feedstock resources for bio-based products is key to contribute to resilience and strategic autonomy of bio-based operations. Industrial biotechnologies have showcased that they can play a key role to address residual biomass into valuable bio-based products. However, scaling up from research to demo scale requires addressing systemic and technical challenges. This entails the integration of adequate pretreatment and conversion processes, tailored to the targeted residual biomass and its…

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes: Member States and Associated Countries contribute to the implementation of area-based management tools, such as protection targets and adaptive management approaches for deep-sea regions under the Treaty on Biodiversity Beyond National Jurisdiction (BBNJ) and the Kunming-Montreal Global Biodiversity Framework (GBF), for Regional fisheries Management Organisations (RFMOs) and for transitions areas with the EU exclusive economic zone notably by identifying Ecologically and biologically significant marine areas (EBSAS), and informing the next Global Assessment of Biodiversity and Ecosystem Services; Public Authorities prioritise deep sea areas for inclusion in their 30% protection target while enhancing maritime spatial planning achieved through science-based information, habitat mapping and ecosystem-based approach, aligned with the EU strategies for biodiversity and climate adaptation by 2030. Scope: The deep sea represents 90% of the Ocean volume and remains the least explored biome of the planet. Nevertheless, we know that the deep sea forms an extensive and complex ensemble of…

Expected Outcome: This action will strengthen Europe's strategic autonomy in quantum-secure communications by advancing core QKD technologies and integration capabilities. Expected results include: Development and demonstration of next-generation QKD systems, with a focus on cost-effectiveness and integration, with specific measurable improvements in one of the following parameters or features: (i) key rate (>1 Mbps over metropolitan distances), (ii) operational coverage of a network at the regional scale, >300 km for fibre-based QKD, including e.g. twin field and free-space links also for non-wired segments and for redundancy, (iii) development and demonstration of advanced quantum cryptographic protocols beyond QKD with provable security advantage over classical cryptographic systems. Implementation of hybrid quantum-classical cryptographic frameworks combining QKD and post-quantum cryptography (PQC), tested on clearly defined real-world applications. Integration of quantum communication components with network equipment and orchestration systems (e.g., software-defined networking). Validation of QKD-based security in high-priority use cases beyond EuroQCI infrastructure,…

Expected Outcome: Projects should contribute to all of the following expected outcomes: Deepened understanding and comprehensive evaluation of cultural policy models, creative industry ecosystems, and strategies for promoting creative industries across world regions, identifying good practices, success stories and replicable models. Innovative practices, policy approaches, shared challenges, and opportunities for cross-regional collaboration and global development of creative industries are identified. International equal partnerships and collaborations are established to exchange cultural policy approaches, boost creative industries, and/or support collaborative production or co-creation, facilitating knowledge transfer and capacity building among participating actors. Actionable strategies are available to policymakers, businesses, and stakeholders, for cross-regional collaborations that strengthen cultural ties, leverage creative industries, culture, and the arts as central to Global Europe, and support global culture- and creativity-driven innovation and resilience. Scope: This topic explores how international partnerships can strengthen cultural policies and creative…

Expected Outcome: Projects should contribute to all of the following expected outcomes: The concept of sustainable competitiveness is analysed taking into account the shifts in geopolitics, global trade patterns, as well as changes in climate, the environment (including biodiversity loss [1] ), technology and demography. Policymakers are provided with recommendations and innovative solutions, including a toolbox to boost Member States and Associated Countries (labour) productivity while ensuring high social and environmental standards and increasing competitiveness within planetary boundaries. Scope: The Future of European competitiveness report (also known as the Draghi report) [2] analysed and discussed the reason for European declining competitiveness, productivity and growth vis-a-vis its main competitors. A competitive economy is defined as an economy whose sustained rate of productivity is able to drive growth and, consequently, income and welfare. Both the economy and the European social model have to adapt to the great drivers of change, including demography, technology, global trade patterns, climate, and geopolitical shifts. From its side, the European social model is…

Expected Outcome: Projects should contribute to all of the following expected outcomes: Policymakers are made aware and are equipped with the knowledge and tools to integrate inclusive and intersectional perspectives into their policymaking, which strengthens their capacity to promote and protect democracy, fundamental rights, and EU values. Researchers gain insights on how to translate their findings on intersectional inequalities and democracy into actionable, evidence-based recommendations, enabling them to effectively inform policy and practice at local, regional, national, and EU levels. Innovative solutions developed under Horizon Europe and other EU-funding programmes empower equally all citizens, to participate in democratic processes and decision-making. Scope: This call topic aims to establish a Research and Innovation Network for a Union of Equality. The proposed network should bring together academic institutions, public bodies and civil society organisations to collaborate and promote the advancement of inclusive, equal, and resilient democratic societies. The proposed network should contribute to the development of a comprehensive approach to democracy, fostering a…

Expected Outcome: Projects should contribute to all of the following expected outcomes. Country government innovation info sheets, trends, inspiring good practices, the most innovative solutions recently developed or work in progress for next-generation governance and future-informed public decision making in EU Member States and Associated Countries (MS/AC). Policy recommendations for both EU level and MS/AC level actions on adopting new governance paradigms, and strategies for enhanced (technical and financial) support for internal government innovation efforts. Publication of lessons learned to enlighten government officials and the public about the often-invisible internal innovation strategies and impactful solutions in national governments. A comprehensive MOOC (Massive Online Open Course) for government officials with relevant examples and cases. Fostering of closer ties and collaboration among MS/AC (and any other relevant actors) to leverage national capabilities in innovative governance and maintain peer learning through e.g. relevant networks and knowledge exchange platforms. Scope: In an era characterized by numerous concurrent crises, accelerated technological…

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes: Reinforcing EU strategic autonomy by reducing non-EU dependencies on critical space EEE components and related technologies across their entire supply chain; Providing unrestricted access to critical space EEE components and related technologies relevant for EU space missions (Galileo, EGNOS, Copernicus, IRIS 2 and EU pilot missions on In-Orbit Space Operations and Quantum Gravimetry); Developing or regaining capacity to operate independently in space by developing resilient space EEE components and related technologies supply chains, relying on EU supply chains and/or trustable and reliable supply chains not affected by non-EU export restrictions; Enhancing competitiveness by developing products and capabilities reaching equivalent or superior performance level than those from outside the EU and compete at worldwide level. Scope: Unrestricted access to state-of-art space EEE components and related technologies is a pre-requisite for the EU space industry responding to EU space missions. However, especially for some families of components, the available solutions in EU do not…

Expected Outcome: The targeted outcomes reflect the above challenges and cover a comprehensive Front End module design which: Covers the FR3 range as defined by the relevant Agenda Item of WRC 27 (7 to 15 GHz range) with possible extension up to 24 GHz if required by some regional implementations, with inherent tuning capabilities to accommodate potential regional variations. Mitigates interferences with incumbent FR3 band users and maximises sharing capabilities across the band in line with the European regulatory approach on spectrum sharing. Enables integration of a large number of antenna elements beyond the State of the Art and support massive MIMO implementation with compensation of increased path loss compared to 5G FR1 implementations. Enables at least an order-of-magnitude increase in RF processing compared to 5G FR1 implementations. Enables 5G cell site reuse and minimises deployment complexity on top of 5G sites deployment. Enables low-cost and low energy implementation of the elementary constituent modules, efficient packaging and is mainly based on the integration of microelectronics heterogeneous technologies where European industry has strong expertise and…

Expected Outcome: Project results are expected to contribute to all the following expected outcomes: Assessment of Europe’s CCAM position in global competition, identifying strategic vulnerabilities, dependencies and opportunities across business models, supply chains, critical components, technological capabilities, infrastructure, and regulatory frameworks, supported by advanced AI-driven analytics and innovation mapping tools. Stakeholder-driven, participatory future scenarios and strategic pathways that define Europe’s leading role in the evolving geopolitical, technological, and economic landscape of CCAM. These should be developed using advanced foresight methods ( e.g. qualitative scenarios, horizon scanning, technology roadmapping, etc.), complemented by iterative validation through a minimum of 3 dedicated Living Labs selected to represent diverse European regions, urbanisation levels, and governance capacities, ensuring a structured, robust, and anticipatory approach to long-term decision-making. A data-driven understanding of the socioeconomic effects of different CCAM deployment pathways, based on a quantified assessment across Member States and Associated Countries,…

Expected Outcome: This action will establish a pan-European open-access testing and experimentation infrastructure for quantum technologies, enabling systematic validation and certification of quantum components and systems. Expected outcomes include: Deployment of distributed quantum testing facilities accessible across Europe, including remote access and standardized test protocols. Provision of certification services aligned with future standardisation efforts, ensuring trust, quality, and interoperability of quantum technologies. Support for SMEs, start-ups, and research institutions in validating quantum components and sub-systems. Strengthening of Europe’s competitiveness by ensuring robust quality assurance mechanisms and accelerating the time-to-market of emerging quantum products. Scope: The proposal should implement the testing-related part of the action plan established under the Framework Partnership Agreement for Qu-Test. The action must include: Expansion and interconnection of open-access testing facilities in multiple Member States, covering a range of quantum technologies (e.g., processors, sensors, photonics, control systems). Development and deployment of…

Expected Outcome: This action will consolidate Europe’s position in superconducting quantum computing through: Establishment of a full-stack superconducting quantum computer aiming at 1.000 physical qubits and QPU architecture based on chiplet technology. The system should feature a scalable and user-adjustable architecture, T1 coherence time above 100 us, gate fidelities (both one- and two-qubit gates, and read-out) of at least 99.9%, read-out speed below 300 ns, two-qubit gate speed below 20 ns. Demonstration of quantum advantage on selected industrial use cases, validated through benchmarking with best-in-class classical methods. Deployment of a cloud-accessible quantum system integrated with high-performance computing environments. Maturation of fault-tolerant quantum computing protocols, including effective quantum error correction and noise mitigation schemes. Delivery of a comprehensive, standardised software stack supporting system bring-up, calibration, control, benchmarking, and user access. Strengthened supply chains and industrial capacity in Europe for superconducting quantum technologies. Scope: The proposal should contribute to the scale-up and practical deployment…

Expected Outcome: This action will strengthen Europe's leadership and strategic autonomy in quantum technologies by advancing experimental pilot line capacities as a vital stepping stone toward future industrial-scale quantum hardware production. Qu-Pilot serves as the critical intermediary between academic research and the stable pilot lines under the Chips Joint Undertaking, offering a testbed for technological innovation, reproducibility, and manufacturability. Expected outcomes include: Deployment of experimental quantum pilot lines addressing diverse platforms and materials, laying the groundwork for broader integration into Chips JU pilot lines. Establishment of scalable and reproducible quantum fabrication processes, advancing TRL 4–6 technologies and addressing early-stage certification, standardisation, and quality control. Reinforcement of a pan-European quantum hardware ecosystem through shared infrastructure and open-access models, fostering participation from SMEs, startups, and research institutes. Demonstrated ability to accelerate technology maturity and feed critical feedback loops into future Chips JU stability pilot lines. Enhanced synergies with testing…

Expected Outcome: This action will advance Europe’s leadership in trapped-ion quantum computing by achieving the following key outcomes: Establishment of a full-stack ion-trap quantum computer aiming at more than 1.000 qubits, fully integrated into high-performance computing (HPC) systems, and accessible via the cloud. Demonstration of quantum advantage for selected real-world applications, validated against benchmarks. Strengthened European capabilities to develop modular, interoperable, and scalable quantum computing architectures. Implementation and demonstration of advanced error correction and fault-tolerant quantum computing techniques. Integration of full-stack hardware-software systems with standardised and certified interfaces. Engagement with industry and academia through open access to quantum computing resources and co-design of applications. Scope: The action should support the scale-up of European trapped-ion quantum computing platforms, aiming at technological maturity and usability for industrial and scientific applications. In particular, the action must address at least two major technical roadblocks defined in the Strategic Research and Industry Agenda (SRIA…

Expected Outcome: The actions funded under this topic should support communities, land managers, local administrators, policy makers, and researchers to deploy solutions contributing to the goals of the EU Nature Restoration Regulation and the new EU bioeconomy strategy, through techniques aligned to the Strategy for European Life Sciences and the EU Biotech Act. Project results are expected to contribute to all of the following expected outcomes: innovative biotechnology and Nature-based Solutions (NbS) [1] are developed and made available to communities, land managers, local administrators and policy makers in Ukraine to progress towards the targets of biodiversity protection and the clean environment and zero-pollution ambition; contribution to the reconstruction, recovery, circularity and upgrading of economy and environment of Ukraine is provided through the remediation of severe ecosystems pollution - due to conflicts - and restoration of ecosystem services. Scope: The recent wars are causing severe environmental degradation across ecosystems – besides the disruption of human lives and dignity - with concentrations of contaminants affecting the quality of air, water, soil,…

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes: improved collection, sorting and recycling technologies that enhance significantly the recovery rates of strategic and critical raw materials from waste from electrical and electronic equipment, reducing the dependence on imported secondary and primary materials, and mitigating the climate and environmental impacts associated with their extraction, including biodiversity loss, by reducing the need for primary raw material extraction and minimising waste; strengthened waste market creation through the development of economically viable and environmentally sound recovery and recycling practices and technologies, with a particular emphasis on secondary strategic raw materials of lower costs and sufficiently high quality and/or purity, promoting a circular economy for electrical and electronic equipment. Scope: As Europe seeks to reduce its dependence on imported critical raw materials and mitigate climate and environmental impacts from extraction, there is a pressing need for innovative and economically viable recycling processes. With the rapid increase in electronic waste,…

Expected Outcome: The successful proposal will contribute to the implementation of the EU Mission on Adaptation to Climate Change and the upcoming European Climate Adaptation Plan. Proposals are expected to contribute to all of the following outcomes: The wide range of solutions tested and deployed in the context of the Adaptation Mission and the good practices emerged in its Community of Practice are harvested, assessed, structured and systematised to support the implementation of the Mission. Regional and local authorities can access, in the local language, the latest and most actionable solutions for climate adaptation relevant to their (climatic) conditions. Adaptation solutions stemming from research and innovation are ready for replication and scale-up, contributing to the delivery of the Adaptation Mission and acceleration of adaptation efforts across Europe. Legacy of the knowledge created by the Mission is also ensured. Knowledge and understanding of the policy implications of adaptation solutions is increasingly utilised in the policy cycles at EU, national, and regional and local levels. Scope: Rationale Grounded in Research and Innovation, EU Missions aim to mobilise…

The Department of Defense (DoD) announces the Fiscal Year 2027 Defense University Research Instrumentation Program (DURIP). DURIP is designed to improve the capabilities of accredited United States (U.S.) institutions of higher education to conduct research and to educate scientists and engineers in areas important to national defense, by providing funds for the acquisition of research equipment or instrumentation. For-profit organizations are not eligible for DURIP funding.

Expected Outcome: Projects should contribute to all of the following expected outcomes: EU, national and local policymakers possess the necessary knowledge to inform the development of election regulations, standards and tools that address the use of digital technologies in elections and political campaigns, ensuring their integrity, inclusiveness, accessibility, fairness, transparency, and security. Organisations involved in electoral processes develop and implement guidelines for the responsible use of digital technologies in elections and political campaigns, aligned with EU and national regulations. Enhanced transparency and accountability in AI-powered political campaigns, achieved through requirements for AI system audits, data disclosure, transparency regarding algorithms and sources of Large Language Models (LLMs), and responsible AI development. Scope: The integrity of electoral processes in Europe is facing challenges in the digital age. The digital transformation of democratic processes has created new avenues for citizen engagement, but it also poses significant risks from disinformation to the integrity of electoral and other democratic processes. Concerns about…

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes: higher and more robust industrial European competitiveness, decarbonisation and strategic autonomy, advancing the lead market for bio-based industry; improved environmental sustainability, with positive impact on climate, pollution and biodiversity, via the standardization of the bio-based sector and products. Scope: Proposals should address the following activities: aiming at overall high sustainability and environmental benefits, and considering the economic feasibility, for high quality of final products, select a bio-based sector/industry [1] to develop or improve knowledge, technology, product, process, service or solution related to Ecodesign applicable to the chosen sector; identify specific gaps in standardization research pipeline, for bio-based products, followed by pre-normative R&D tasks, aiming at high socio-economic and positive environmental impact, allowing the development and deployment of safe and sustainable, circular bio-based value chains/products, with reduced pressure on biological resources and ecosystems, leading to the consistent improvement of their…

Expected Outcome: Successful proposals will contribute to the updated EU Bioeconomy Strategy, the Circular Economy Act, the Clean Industrial Deal, the European Chemical Industry Action Plan and the Chemicals Strategy for Sustainability. Projects results are expected to contribute to the following expected outcomes: Enhancing competitiveness, efficiency, sustainability, circularity and safety of industrial biorefineries. Efficient, selective and scalable separation and purification technology platform(s) with high potential to be integrated within existing and/or new biorefineries. Purity and stability of targeted intermediates/product(s) compatible with further conversion requirements. Scope: While significant advancements have been made in recent years in the development of core biorefinery processes, challenges remain in separation and purification steps. Separation and purification, both upstream and downstream of biorefinery processes, play a key role in determining quality and purity of the intermediates and products. They usually account for a significant share of the whole process costs and are often a relevant bottleneck towards full-scale deployment and commercialisation…

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes: Reinforcing EU strategic autonomy by reducing non-EU dependencies on critical space EEE components and related technologies across their entire supply chain; Providing unrestricted access to critical space EEE components and related technologies relevant for EU space missions (Galileo, EGNOS, Copernicus, IRIS 2 and EU pilot missions on In-Orbit Space Operations and Quantum Gravimetry); Developing or regaining capacity to operate independently in space by developing resilient space EEE components and related technologies supply chains, relying on EU supply chains and/or trustable and reliable supply chains not affected by non-EU export restrictions; Enhancing competitiveness by developing products and capabilities reaching equivalent or superior performance level than those from outside the EU and compete at worldwide level. Scope: Unrestricted access to state-of-art space EEE components and related technologies is a pre-requisite for the EU space industry responding to EU space missions. However, especially for some families of components, the available solutions in EU do not…

Expected Outcome: Objectives and profile of the ERC Plus Grant Principal Investigator The ERC Plus Grant supports outstanding Principal Investigators who address a major scientific challenge. Applications for ERC Plus Grants should be for projects that could not be carried out with a regular ERC grant. Applicants should explain how the proposed project aims go beyond those of a regular ERC project, for example, because they have a vision to transform their field or open a new field of research. Scholars at all career stages can apply for an ERC Plus Grant if they have an outstanding record of scientific achievement at the forefront of their field. Their intellectual leadership will be evaluated in comparison to peers at their own career stage. It is expected that a researcher may be the Principal Investigator of only one ERC Plus Grant in their lifetime. Applicants should be aware that every year, only some 30 ERC Plus Grants can be awarded across all fields and all career stages, compared to approximately 1000 Starting, Consolidator and Advanced Grants. This level of competitiveness should be taken into account when considering whether to submit an application. Size of ERC Plus…

Expected Outcome: The topic encompasses actions within the scope of the co-programmed European Partnership on Globally Competitive Space Systems (‘Space Partnership’) in the areas of satellite communication (SatCom), Earth Observation (EO) and New Commercial Space Transportation Solutions and is part of cohesive activities in the domain of digital developments under the grand heading of “digitalisation for commercial space solutions”. Digitalisation is a major enabler for enhancing the value of an End-to-End EO and SatCom system. Under the area of Using Space on Earth related to SatCom and EO, below this topic focus on the fast increment of the Low to Mid TRL level building blocks for key technologies [1] required to strengthen competitiveness in these domains. Projects are expected to contribute to one or several of the following outcomes: New commercial services and applications enabled by increased digitalisation of space solutions; Favouring a competitive and sustainable European Space Sector; Enable the European Space Industry to maintain a significant share of the global connectivity market; Next generation Earth observation and SatCom payloads, technologies and processing…

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes: significant advance in the development of innovation in biotechnology, life sciences and/or biomanufacturing concepts, preparing future deployment of bio-based and bio-inspired processes, products and materials, as a basis for sustainable, fair, safe and circular value chains, contributing to decarbonisation, industrial competitiveness and the strategic autonomy of the EU and Associated Countries; improved environmental sustainability of the developed innovative bio-based solutions, with positive and quantifiable impact on climate and biodiversity, and circularity of the European bioeconomy via enhanced resource efficiency, including of biological feedstocks, water and energy, integrating bio-based sector to minimize and remediate waste production. Scope: Actions funded under this topic are relevant to the EU policies related to the European Commission communication on ‘Building the future with nature: Boosting Biotechnology and Biomanufacturing in the EU’, the Life Sciences Strategy, the upcoming EU Biotech Act, and Circular Economy Act, the EU strategy on research and…

Expected Outcome: Projects should contribute to all of the following expected outcomes: Greater integration of SSH and STEM [1] research and innovation in R&I initiatives funded at EU level, national and/or regional level, as well as in R&I policies by promoting dialogue, mutual learning and strategic cooperation among research funders and policy makers in the EU. Developing and maintaining a new, common, comprehensive ‘Monitoring and Impact Evaluation Framework’ for SSH integration in current and future EU R&I initiatives. Enhanced facilitation of knowledge exploitation and support to the cooperation between projects and stakeholders, as well as R&I policies involved in projects and other types of cross-border networks dealing with SSH and STEM research and innovation. Scope: As mentioned in the Report ‘Align, Act, Accelerate: Research, Technology and Innovation to boost European Competitiveness’ [2] , European RD&I can provide a new understanding of and solutions to tackle societal challenges. Social sciences and humanities (SSH) and Science, Technology, Engineering and Maths (STEM) improve the research activities, outcomes and impacts of Horizon Europe, because they enable a…

Expected Outcome: The project results are expected to contribute to some of the following expected outcomes: research into safety of innovative reactors, small modular reactors (SMRs) – both light water SMRs (LW-SMRs) and Gen-IV-based advanced modular reactors (AMRs); design or demonstration of SMRs and fuel cycles’ viability; and efficient integration within low-carbon and smart energy systems; research support towards a shared and consistent approach among regulators’ TSOs to safety requirements for different advanced energy systems and applications (e.g. industrial heat, district heat and the maritime sector), supported by regular exchanges and reviews and workshops with licensees, SMR developers, and research organisations, thereby further improving safety across the EU; emphasis on innovation in the safety aspects of LW-SMRs and AMRs; establishment of operating rules for specific services for innovative reactors, incorporating emerging instrumentation and digital technologies that offer potential improvements for in-service operation; research into fuel cycles (including their key features: inherently safe design, generation of less high-level waste and improved use of…

Expected Outcome: The focus needs to be on areas where Digital Partnership countries bring strong complementary expertise, including advanced packaging, heterogeneous integration, and photonic chip technologies. The topic would aim to foster collaboration between European and Digital Partnership countries’ R&I communities. Projects are expected to contribute to the following outcomes: • Innovative design and integration concepts for neuromorphic computing systems supporting very low energy consumption, connectivity, embedded functions for mobile applications. • Alternative manufacturing process technologies for semiconductor chips including frontend or backend for heterogenous integration. The technologies should sustain in the mid- and long-term the fast-paced evolution of device performance, miniaturisation and cost, while reducing the environmental footprint. • Very advanced packaging solutions aiming heterogeneous integration of multiple functions and materials for applications in communication (RF, mmW or THz), sensing, actuating, power management and active/passive integration.

Expected Outcome: The project’s results are expected to contribute to some of the following expected outcomes. Continuing safety assessment and long-term operation compliance that address technical challenges, regulatory expectations and economic competitiveness goals. Licence-holders and regulators will ensure the successful implementation of the requirements of the Nuclear Safety Directive  [1] , Basic Safety Standards Directive  [2] , Radioactive Waste Management Directive  [3] and topical peer reviews  [4] for current and planned nuclear power plants and research reactors. Safety assessment of ageing management programmes and optimisation of safety solutions; as well as the development and validation of advanced tools for ageing management and evaluation of reactors’ safety margins. The aim is to prevent and mitigate risks (including those associated with severe accidents) by using innovative cross-cutting technologies (applicable to multiple reactor technologies), digital upgrades, digital twins, AI/ML-assisted defect detection, advanced multi-physics (including fluid structure interaction) and/or multiscale modelling and simulation, as well as PSA updates for extended…

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes: most Member States and regions [1] have established the bioeconomy as an important policy field. Effective bioeconomy policies and strategies are developed and implemented with specific impact targets in mind; policies and action plans and roadmaps are coordinated across parts of government (e.g. Ministries) and across the quadruple helix (government, sectors, research & innovation, society) to take into account the cross-sectoral and place-based character of the bioeconomy, and the need for a whole of government approach. Platforms are established to facilitate dialogue, experimentation, learning and coordination; all actors of the quadruple helix (e.g. policy makers, NGOs, economic sectors) are aware of the bioeconomy, as well as of the potential and challenges that are specific for their perspective and context. The bioeconomy concept, its principles and its solutions and innovations are mainstreamed by sectors (e.g. food, textiles, chemicals, energy, agriculture, forestry). Scope: Proposals should: establish a European Bioeconomy Policy Support Hub to provide innovative…

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes: Public authorities, industry, technology providers, energy producers and consumers profit from de-risking of cost-effective essential value chains of those renewable fuel technologies that can contribute to domestic commercial fuel production beyond 2030 customized to their needs, from improved access to better financing exploiting synergies across funding schemes, and from more effective market uptake, business models, increased competitiveness, and commercialization opportunities. Energy producers, clean tech manufacturing industries, researchers and consumers benefit from improved performance, lower environmental impact, security and competitiveness of ad-hoc renewable fuel technologies compared to existing ones, as well as new market opportunities. Community, public authorities and industry benefit from sharing the de-risking cost and reducing it by engaging several competing solution suppliers/technology providers in parallel, boosting transnational public and private investments in de-risking and attracting new players to tackle supplier lock-in issues The implementation…

The Office of Science (SC) of the Department of Energy (DOE) hereby announces its continuing interest in receiving applications for support of work in the following program areas: Advanced Scientific Computing Research, Basic Energy Sciences, Biological and Environmental Research, Fusion Energy Sciences, High Energy Physics, Nuclear Physics, and Isotope R&D and Production. On September 3, 1992, DOE published in the Federal Register the Office of Energy Research Financial Assistance Program (now called the Office of Science Financial Assistance Program), 10 CFR 605, as a Final Rule, which contained a solicitation for this program. Information about submission of applications, eligibility, limitations, evaluation and selection processes and other policies and procedures are specified in 10 CFR 605.   This NOFO is our annual open solicitation that covers all research areas in SC and is open throughout the Fiscal Year. Any research within SC’s Congressionally authorized mission may be proposed under this NOFO.   This NOFO will remain open until September 30, 2026, 11:59 PM Eastern Time, or until it is succeeded by another issuance, whichever occurs first. This NOFO succeeds DE-FOA-0003432, which was published September 30, 2024.

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes: Reinforcing EU strategic autonomy by reducing non-EU dependencies on critical space Equipment and related technologies across their entire supply chain; Providing unrestricted access to critical space Equipment and related technologies relevant for EU space missions and pilots (e.g. In-Orbit Space Operations); Developing or regaining capacity to operate independently in space by developing resilient space Equipment and related technologies supply chains, relying on EU supply chains and/or trustable and reliable supply chains not affected by non-EU export restrictions; Enhancing competitiveness by developing products and capabilities reaching equivalent or superior performance level than those from outside the EU and compete at worldwide level. Scope: Unrestricted access to state-of-art space equipment and related technologies is a pre-requisite for the EU space industry responding to EU space missions. However, especially for some families of equipment, the available solutions in EU do not meet the current high-performance space requirements. Currently, alternative products…

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes: Police Authorities in Europe are equipped with specialised skills and technologies to counter an increase in illegal activities related to the climate change and the emergence of new (opportunistic) criminal patterns; Improved understanding by policymakers of the effects of climate change on law enforcement with a view of developing related effective European policies; improved knowledge of the impacts of climate change phenomena on social dynamics which can raise demands from public authorities to keep public order, moving beyond traditional perspectives about crime and terrorism. Scope: Global climate change is a megatrend expected to affect our societies over the next decade. As stated in “Germany: National interdisciplinary climate risk assessment” [1] , “We are already living in the climate crisis. This brings substantial security risks at global and national levels. (...) Anyone thinking about security needs to think about climate as well”. Climate change will affect European law enforcement in various ways [2] , [3] . Notably, it is likely to create new…

Expected Outcome: Project results are expected to contribute to some or all of the following outcomes: Identification and analysis of potential new security risks related to innovative technologies being deployed in the urban and peri-urban environments; Innovative and modern tools to identify and measure changes in urban and peri-urban areas caused by the green transition, insofar as they concern security and possible resilience approaches; Verification of measures countering potential safety and security risks, hazards and challenges arising in areas hosting green technologies; Contribution to building awareness and societal acceptance for the safety and security aspects of the green transition; Impacts of incidents involving new and emerging technologies are examined, including environmental and climate risks; Security, safety and resilience aspects of the supply chains of green technologies are analysed, including the technological and resource dependencies, and their aligning with the European strategic autonomy principle; Authorities and critical infrastructure operators are equipped with efficient evaluation methodologies for safe and secure deployment and integration of…

Expected Outcome: Deep sedimentary/basement reservoirs are usually characterized by low permeability, high drilling cost and a scarcity of data, as they are typically ignored by hydrocarbon exploration. Major exploration challenges relate to predicting deep sedimentary and basement reservoir structures and properties to identify suitable locations for reservoir-independent approaches, capable of overcoming the low permeability obstacle, such as Enhanced Geothermal Systems (EGS) or closed-loop geothermal systems. Project results are expected to contribute to all of the following expected outcomes: Increased knowledge base for developers to unlock unexploited geothermal resources, increase drilling success rate, increase geothermal sources performance and reduce the risk of induced seismicity and deploy geothermal energy in a sustainable way in environmental (notably on biodiversity and pollution) and socioeconomic terms. Citizens and local communities are engaged and benefit from local, more secure and affordable renewable energy sources. Scope: Advanced methods, technologies and conceptual models, for different geological settings, to identify suitable conditions for geothermal…

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes: Development of innovative tools and methodologies to monitor and improve risk awareness across society, integrating diverse community perspectives and leveraging advanced technologies; Development and uptake solutions and tools for the successful increase of safety culture and societal resilience of communities with concrete material, while considering also the inclusion and protection of marginalized populations in disaster scenarios; Creation of comprehensive, inclusive preparedness plans that involve all societal sectors and governance levels, ensuring coordinated and effective responses to disasters (such as from early warning to early action), including scarcity of resources; Establishment of a resilient, adaptive response framework that enhances collaboration between public authorities, communities, and private sectors, improving overall disaster resilience. Scope: Building on the whole-of-society and whole-of-government approach, this topic should contribute to enhancing risk awareness and disaster preparedness through the development of innovative tools,…

As the home of the United Nations Office for Outer Space Affairs (UNOOSA) and the United Nations Committee on the Peaceful Uses of Outer Space (COPUOS), Vienna provides a unique multilateral platform for fostering these partnerships. Building upon the successful inaugural U.S. Space Forum in 2025, the U.S. Mission to the International Organizations in Vienna (UNVIE) is launching Project Constellation: Building a Constellation of Outer Space Partners at the United Nations as a long-term international partnership platform that strengthens collaboration among governments, industry, academia, entrepreneurs, and international organizations while supporting capacity building in emerging space economies that advances practical implementation of international obligations and non-binding guidelines and best practices adopted through COPUOS. Consistent with the objectives of Economic Support Funds (ESF), Project Constellation seeks to strengthen innovation ecosystems, promote entrepreneurship and commercial engagement, build institutional and workforce capacity, and expand economic opportunities through sustainable international partnerships. To be considered for funding under this opportunity, applicant SHALL: - Have demonstrated previous experience designing and delivering international training, capacity building, workforce development, educational exchanges, or public diplomacy programming on U.S. civil and/or commercial space activities. This should be addressed withing the project narrative section of your application.   - The capacity to complete grant signing by September 31, 2026 and begin supporting the 2026 U.S. Space Forum (October 15-16).

Expected Outcome: Project results are expected to contribute to the following expected outcomes: European space science breakthroughs fostered by data analysis and exploitation of European missions (incl. low-cost/small satellite) and instruments, in conjunction, when relevant, with international missions. This data may also originate from European in-orbit validation experiments with a focus on space science and exploration. A higher number of European scientific publications based on space data, high-level data products made available through appropriate archives, and tools and methods developed for the advanced processing of data. Increased collaboration of scientific teams both within and outside Europe across different domains, adding value to existing activities on European and international levels and enhancing and broadening research partnerships. European scientific excellence and development of leading-edge scientific research in Europe. Scope: The aim of this topic is the analysis (including validation) and exploitation of acquired and available data provided by scientific and exploration instruments and missions in their pre-operative, operative, post-operative or data…

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes: Increased understanding of European policy makers, research community, biotech companies, and relevant security practitioners of the threat of bioterrorism and of synthetic biology, including a thorough lawful analysis of what needs to be monitored in this context, what needs to be regulated and how; Awareness raised within the related scientific community how research in synthetic biology can be used for malicious purposes. Scope: The rising threat of bioterrorism is driven by recent scientific advancements, notably by growing accessibility of synthetic biology, genetic engineering, related commercial services and public databases, which in turn enhance their obtainability to non-state actors and individuals with malicious intentions. The proliferation of do-it-yourself biohacking and community laboratories, including gene editing and sequencing technology, dropping costs of equipment and increased simplicity of use may inadvertently facilitate knowledge and skills dissemination about biological threats and open new pathways for bioterrorism. Challenges in detection,…

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes: Accelerated adoption of high-TRL (Technology Readiness Level) disaster risk solutions across diverse sectors; Facilitated integration of innovative technologies into existing disaster prevention, preparedness, response, and recovery frameworks; Promoted collaboration among stakeholders to scale proven solutions and enhance resilience; Addressed barriers to deployment, ensuring accessibility and usability of advanced DRS technologies; Strengthened evidence-based decision-making through demonstration and validation of high-TRL solutions in real-world scenarios; Promoted visibility of civil security research results. Scope: This topic aims to foster the widespread adoption and integration of high-TRL (Technology Readiness Level) disaster risk solutions (DRS) across multiple sectors, enhancing societal resilience to various hazards, including climate. The focus is on overcoming barriers to deployment, ensuring accessibility, and strengthening collaboration among stakeholders to drive innovation uptake. Projects should promote the adoption of high-TRL solutions by public and…

The EDU Core Research (ECR) program offers this ECR:Core solicitation and invites proposals for fundamental research (curiosity-driven basic research and use-inspired basic research) that contributes to the general, explanatory knowledge that underlies STEM education in one or more of the three broadly conceived Research Areas: Research onSTEM Learning and Learning Environments, Research on Broadening Participation in STEM fields, andResearch on STEM Workforce Development. Within this framework, the ECR program supports a wide range of fundamental STEM education research activities, aimed at learners of all groups and ages in formal and informal settings. Fundamental researchgenerates knowledge and understanding with the potential for broad relevance. The potential implications of ECR fundamental research for improving STEM education practice may be indirect and long-term rather than direct and immediate. Moreover, whether they include basic or use-inspired basic research, all successful ECR:Core proposals focus on the advancement or refinement of foundational knowledge for STEM education. The amount of funding and duration requested in proposals submitted to the ECR:Core solicitation should align with the maturity of the proposed work and the size and scope of the empirical effort. The solicitation has three levels of funding with a range of budget sizes, and proposals may request a duration of 3 to 5 years for any level: (1)Level I proposals may request up to $500,000; (2)Level II proposals may request up to $1,500,000; (3)Level III proposalsmay request up to $2,500,000. All proposals should justify the level of funding and duration in the project description.

Apply for funding to work with overseas researchers in the State of São Paulo, Brazil. Submit a collaborative research grant application within the remit of Arts and Humanities Research Council (AHRC) and State of São Paulo Research Foundation (FAPESP). You must be based at a UK research organisation eligible for AHRC funding. There is no limit on the value of the grant, the value specified within the summary page is an example.

Apply for Arts and Humanities Research Council (AHRC) standard research grant funding to support well-defined collaborative projects across the arts and humanities, in areas covered by our remit. You must be based at a UK research organisation eligible for AHRC funding. There is no limit on the value of the grant, the value specified within the summary page is an example.

Apply for funding to work with overseas researchers in Luxembourg. Submit a collaborative research grant application within the remit of Arts and Humanities Research Council (AHRC) and Fonds National de la Recherche (FNR). You must be based at a UK research organisation eligible for AHRC funding. There is no limit on the value of the grant, the value specified within the summary page is an example.

Apply for funding to pursue an adventurous, ambitious, curiosity-driven project in environmental research. You must be: • based at a UK research organisation eligible for Natural Environment Research Council (NERC) funding • in a role that meets the individual eligibility requirements There is no limit on the value of the grant, the value specified within the summary page is an example.

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes: Integrated single-hazard systems into multi-hazard next generation predictive models to assess cascading effects (e.g., heatwave, floods, droughts, landslides, heavy rain) and interactions across meteorological, geophysical, and technological hazards; Enhanced hazard forecasting and response through research on model integration and platform interoperability; Development of holistic risk and resilience metrics to support multi-hazard prevention strategies, encompassing main physical, economic and social effects; Improvement of analysis models considering evolving vulnerability state, due to cascading and cumulative effects, through numerical simulations and experimental tests, possibly also supported by AI applications; Collected reliable data (same granularity and format) and ways to share and analyse it. The interoperability of all kinds of systems and information sharing is crucial, based on the need-to-know principle; Improved knowledge/experience-sharing from past emergencies to cope with future emergencies, also strengthening trans-national knowledge and data…

COE for Technical Training and Human Performance

Expected Outcome: Project results are expected to contribute to some or all of the following expected outcomes: Improved preparedness, evidence-based approaches and response capabilities, along with a strengthened ability to mitigate risks from diverse threats, by integrating validated disruptive technologies into real-world operations; Accelerated adoption of innovative solutions by reducing barriers through rigorous testing and validation, fostering collaboration among public authorities, industry, and researchers to align technologies with real-world needs. Scope: This topic aims to support the integration of disruptive technological innovations [1] into civil security by strengthening research and innovation activities that enhance preparedness, response capabilities, and risk mitigation. A key focus is bridging the gap between early-stage, low Technology Readiness Level (TRL) research and applied security solutions, ensuring that emerging technologies are effectively transitioned into operational use. Proposals should prioritize disruptive solutions that address diverse security threats while improving the efficiency and effectiveness of civil security operations. Emphasis…

Expected Outcome: Project results are expected to contribute to all of the following expected outcomes: Demonstrated approaches aligned with NEB allow architects, designers, spatial planners and neighbourhood [1] decision makers to ensure an efficient and effective integration of user perspectives in the spatial design and/or transformation of public spaces. The demonstrated approaches deliver positive climate, environmental, social and cultural impact (such as addressing inequalities and enhancing social cohesion, community [1] resilience, civic engagement and a sense of security, ownership and belonging). Scope: The design of neighbourhood public spaces defines their functionality, but also other aspects such as power dynamics and sense of belonging. A fair green transition [1] calls for neighbourhood public spaces to be designed and managed for diverse users. Integrating new methods (such as research-by-design, security-by-design [4] , or life-centric design) in the architectural design and spatial planning of public space can help reflect on the values, practices and stakeholder relations that underpin the design of public spaces; rethink how public spaces are understood;…

Expected Outcome: The Hop-on Facility allows for legal entities from Widening countries to join already funded Horizon Pillar II ‘main’ work programme and EIC Pathfinder collaborative R&I actions, subject to the agreement of the respective consortium and provided that legal entities from such countries are not yet participating as beneficiary, associated partner, or affiliated entity. The scheme aims to improve the inclusiveness of Horizon Europe. Selected consortia will be invited to submit a grant agreement amendment request of the eligible already funded action. Project results are expected to contribute to the following outcomes: At system level, mobilise excellence in the Widening countries, increase visibility of the beneficiaries from the widening countries, improve knowledge circulation, and boost their participation in specific thematic domains; At consortium level, open up established networks to new connections and partnerships, improve research excellence of the Widening country’s institutions in specific fields, enlarge outreach of the participants’ R&I actions and provides access to new talent pools; At the level of the Widening beneficiary, develop new competencies…

The DOE Office of Science (SC), Office of Critical Minerals and Energy Innovation (CMEI), Office of Environmental Management (EM), Office of Nuclear Energy (NE), Office of Electricity (OE), and Hydrocarbons and Geothermal Office (HGEO) hereby announce interest in receiving applications from interdisciplinary teams addressing the Genesis Mission National Science and Technology Challenges to accelerate scientific discovery and research and development (R&D) workflows using novel artificial intelligence (AI) models and frameworks. By achieving AI advantage, these teams will advance the DOE's mission and ensure America’s security and prosperity by addressing energy, environmental, and nuclear challenges through science and technology. Teams are encouraged to leverage the extensive scientific and data resources of the DOE/National Nuclear Security Administration (NNSA), the National Laboratories, U.S. industry, and academia. The resulting AI models and workflows, if successful, may be integrated into the American Science Cloud.   DOE is soliciting new FY26 Phase I small team and Phase II large team applications in the following topic areas: advanced manufacturing, biotechnology, critical materials, nuclear fission, nuclear fusion, quantum information science, semiconductors and microelectronics, discovery science, and energy (see specific focus areas in Section III Program Descriptions).   In addition, this RFA will remain available to allow the recipients of FY26 Phase I awards to apply for larger team Phase II awards. In a few weeks, DOE plans to amend the RFA to clarify the LOI and application guidelines for FY26 Phase II awards. In FY27, DOE plans to amend the RFA or to issue an alternative funding opportunity to update the topic and focus areas to allow a second competition of Phase I small team applications and Phase II large team applications.

The U.S. Army Corps of Engineers (USACE) Engineer Research and Development Center (ERDC) is issuing this announcement for various research and development topic areas. The ERDC consists of the Coastal and Hydraulics Laboratory (CHL), the Geotechnical and Structures Laboratory (GSL), the Environmental Laboratory (EL) and the Information Technology Laboratory (ITL) in Vicksburg, Mississippi, the Cold Regions Research and Engineering Laboratory (CRREL) in Hanover, New Hampshire, the Construction Engineering Research Laboratory (CERL) in Champaign, Illinois, and the Geospatial Research Laboratory (GRL) in Alexandria, Virginia. The ERDC is responsible for conducting research in the broad fields of hydraulics, dredging, coastal engineering, instrumentation, oceanography, remote sensing, geotechnical engineering, earthquake engineering, soil effects, vehicle mobility, self-contained munitions, military engineering, geophysics, pavements, protective structures, aquatic plants, water quality, dredged material, treatment of hazardous waste, wetlands, physical/mechanical/ chemical properties of snow and other frozen precipitation, infrastructure and environmental issues for installations, computer science, telecommunications management, energy, facilities maintenance, materials and structures, engineering processes, environmental processes, land and heritage conservation, and ecological processes. This announcement is continuously open; pre-proposals may be submitted and will be reviewed at any time throughout the year. The availability of funds may limit the ability of the U.S. Government to make awards in specific areas, nevertheless pre-proposals are sought under this announcement for all research areas identified. For additional details on the research topic areas and how to submit pre-proposals, please go to: https://www.erdcwerx.org/u-s-army-engineer-research-and-development-center-broad-agency-announcement/

The Division of Mathematical Sciences (DMS)in the Directorate for Mathematical and Physical Sciences (MPS) at the National Science Foundation (NSF)and the National Institute of General Medical Sciences (NIGMS) at the National Institutes of Health (NIH)plan to support fundamental research in mathematics and statistics necessary to answer questions in the biological and biomedical sciences. Both agencies recognize the need to promote research at the interface between mathematical and life sciences. This program is designed to encourage new collaborations, as well as to support innovative activities by existing teams. The joint DMS/NIGMS initiative offers two submission tracks: Track 1 - for projects with a total budget of up to $600,000 for an award duration of 3 years, and Track 2 - for projects with a total budget of up to $1,200,000 for an award duration of 3-4 years.

AHRC awards to support researchers without prior experience of leading a significant research project to accelerate their trajectory as independent researchers, to unlock their potential and build leadership and convenor experience. You must be based at a UK research organisation eligible for AHRC funding. There is no limit on the value of the grant, the value specified within the summary page is an example.

Objective: The ERC Proof of Concept Grants aim at facilitating exploration of the commercial and social innovation potential of ERC funded research and are therefore available only to Principal Investigators whose proposals draw substantially on their ERC funded research. Scope: Size of ERC Proof of Concept Grants : The financial contribution will be awarded as a single lump sum of EUR 150 000 for a period of eighteen months . Extensions of the duration of Proof of concept projects may be granted only exceptionally. The lump sum will cover the beneficiaries' direct and indirect eligible costs for the project: if the project is implemented properly the amounts will be paid regardless of the costs actually incurred. The lump sum is designed to cover the beneficiaries’ personnel costs, subcontracting costs, purchase costs, other cost categories, and indirect costs. Profile of the ERC Proof of Concept Eligible Principal Investigator The ERC Proof of Concept Grant is open to Principal Investigators whose ERC main frontier research grant is ongoing, or Principal Investigators whose ERC main frontier research grant ends on or after 1 January 2025. For further information please see the…

Supports mathematical research in areas where computation plays a central and essential role, emphasizing analysis, development, and implementation of theoretically justified and efficient algorithms. The combination of these elements resulting in innovative computational methods is a hallmark of the program. Proposals ranging from single investigator to interdisciplinary team projects that not only create and analyze new computational mathematics techniques but also implement them to model, study, and solve important application problems are strongly encouraged, as is providing opportunities for rigorous mathematical training of junior computational mathematicians through research involvement. Conferences Proposals to the Computational Mathematics Program for conferences or workshops must be submitted through the program solicitation "Conferences and Workshops in the Mathematical Sciences" (link below). Principal Investigators should carefully read the solicitation to obtain important information regarding the substance of proposals for conferences, workshops, and similar activities. Unless an exception from the program is granted, to facilitate timely notification of the availability of support, the following requirements are in effect: Proposals for conferences, workshops, etc., to be held in the US must be submitted at least 6 months in advance of the conference start date; Proposals to support group travel to meetings outside the US must be submitted at least 8 months in advance of the meeting start date; Proposals for conferences, workshops, etc., whose budget request exceeds $50,000 must be submitted during the annual Computational Mathematics Program submission window. Conference proposals to the Computational Mathematics Program whose submission dates do not conform with the requirements described above will be returned without review.

Flexible awards to fund fundamental research that leads to new research agendas, networking activity and idea generation, which enables the development of further research opportunities and new research agendas. There is no limit on the value of the grant, the value specified within the summary page is an example.

Expected Outcome: Excellence Hubs allow innovation ecosystems in Widening countries and beyond, to team up and create better linkages between academia, business, government and society. This will foster a place-based innovation culture in Widening countries based on a strategic agenda aligned with regional or national smart specialisation strategies, and clearly identified expectations for economic and societal impacts. Projects should contribute to the following outcomes: Excellent and sustainable regional R&I ecosystems in Widening countries and beyond in relevant domains of cutting-edge science and innovation; Long term joint R&I strategies underpinned by concrete action plans of European relevance; Common investment plans for R&I, including infrastructures, leveraging national, regional and European funds as well as private capital in a synergetic manner; R&I pilot projects alongside a joint strategy and in line with regional and national strategies, notably regional innovation strategies for smart specialisation (RIS3); New competencies and skills for researchers, entrepreneurs and professionals in R&I intensive domains; Strengthened linkages between science, businesses and…

The National Science Foundation (NSF) and the National Institutes of Health (NIH) are interested in proposals that will propel our understanding of the biomedical research enterprise by drawing from the scientific expertise of the science of science policy research community. NSF promotes the progress of science by maintaining the general health of research and education across all fields of science and engineering. The Social, Behavioral and Economic Sciences (SBE) Directorate within NSF supports basic research on people and society. The SBE sciences focus on human behavior and social organizations; how social, economic, political, cultural and environmental forces affect the lives of people from birth to old age; and how people in turn shape those forces. SBE's Science of Science: Discovery, Communication and Impact Program (SoS:DCI) supports research designed to advance the scientific basis of science and innovation policy. The NIH is the U.S. federal agency charged with supporting biomedical research in the U.S.The National Institute of General Medical Sciences (NIGMS) within the NIH supports basic biomedical research that increases understanding of biological processes and lays the foundation for advances in disease diagnosis, treatment and prevention. Both NSF and NIH believe that there are opportunities and needs for building and supporting research projects with a focus on the scientific research enterprise. The two agencies also recognize that when programmatic goals are compatible, coordinated management and funding of a research program can have a positive synergistic effect on the level and scope of research and can leverage the investments of both agencies. Therefore, NIGMS and SBE are partnering to enable collaboration in research between theSoS:DCI program and NIGMS. This partnership will result in a portfolio of high-quality research to provide scientific analysis of important aspects of the biomedical research enterprise and efforts to foster a diverse, innovative, productive and efficient scientific workforce, from which future scientific leaders will emerge. Prospective investigators are strongly encouraged to discuss theirproposals with the program officers before submission to determine project relevance to the priorities of both SBE and NIGMS. Specific questions pertaining to this solicitation can also be directed to the SBE and NIGMS program officers.

Expected Impact: The prize will boost public awareness of the potential, importance and contribution of women to the EU innovation ecosystem and create strong role models, inspiring more women to become innovators themselves. Expected Outcome: The prize will boost public awareness of the potential, importance and contribution of women to the EU innovation ecosystem and create strong role models, inspiring more women to become innovators themselves. Objective: The European Prize for Women Innovators celebrates the women entrepreneurs behind Europe’s game-changing innovations, so that they may inspire other women and girls realise their full potential as the EU’s future scientists, innovators, and tech leaders. This prize supports a culture within research and innovation organisations and companies allowing women to become the innovators and entrepreneurs of tomorrow. The prize is awarded every year to women from across the EU and countries associated to Horizon Europe, who have transformed their ideas into disruptive innovations to benefit people and the planet and who are inspiring leaders. As for the previous edition, the 2027 European Prize for Women Innovators is organised in…

Expected Impact: The prize will boost public awareness of the potential, importance and contribution of women to the EU innovation ecosystem and create strong role models, inspiring more women to become innovators themselves. Expected Outcome: The prize will boost public awareness of the potential, importance and contribution of women to the EU innovation ecosystem and create strong role models, inspiring more women to become innovators themselves. Objective: The European Prize for Women Innovators celebrates the women entrepreneurs behind Europe’s game-changing innovations, so that they may inspire other women and girls realise their full potential as the EU’s future scientists, innovators, and tech leaders. This prize supports a culture within research and innovation organisations and companies allowing women to become the innovators and entrepreneurs of tomorrow. The prize is awarded every year to women from across the EU and countries associated to Horizon Europe, who have transformed their ideas into disruptive innovations to benefit people and the planet and who are inspiring leaders. As for the previous edition, the 2027 European Prize for Women Innovators is organised in…

Under this FY26 grant agreement, academic partners will establish the National Center for Narrative Intelligence (NCNI) by executing RDT&E tasks across the following four pillars: workforce development, applied research infrastructure, collaborative networks, and strategic analysis for DoW leadership.

The FY23 -FY28 Broad Agency Announcement for Extramural Biomedical Research and Development - HT9425-23-S-SOC1.

Apply for funding for a research grant in any area within the remit of the Biotechnology and Biological Sciences Research Council (BBSRC). You must be based at a UK research organisation eligible for BBSRC funding. There is no limit on the value of the grant, the value specified within the summary page is an example.

Apply for funding for a research grant in any area within the remit of the Biotechnology and Biological Sciences Research Council (BBSRC). You must be based at a UK research organisation eligible for BBSRC funding. There is no limit on the value of the grant, the value specified within the summary page is an example.

The USAFA invests in an active research program for three main reasons. First and foremost, research significantly enhances the cadet learning experience. Our research is done by, for and with cadets who work alongside fellow cadets and faculty mentors. Research provides cadets with rich independent learning opportunities as they tackle ill-defined problems and are challenged to apply their knowledge and abilities. Second, our research program provides opportunities essential for faculty development. Research broadens and deepens the experience base of the faculty. This infuses current, relevant, state-of-the-art and cutting-edge applications and examples into the curriculum. This also helps our faculty remain current in their respective fields. Third, at USAFA we strive to conduct research to enhance the ability of the Air Force to perform its mission. There are ongoing research projects spanning topics as diverse as super hypersonics, cyber security, spatial disorientation, athletic performance and homeland defense. This BAA offers a vehicle for research to be performed to satisfy these three objectives, while also meeting research needs of industry counterparts/serve a public purpose. USAFA’s partnerships with non-Government firms enables development in the public arena, stimulating the studies in the greater technical community. All awards issued against this BAA must serve to benefit the objectives identified above.

Apply for funding to work with overseas researchers in the Unites States (US). Submit a collaborative research grant application within the remit of AHRC and US National Science Foundation, Social, Behavioural and Economic Sciences Directorate (NSF-SBE). You must be based at a UK research organisation eligible for AHRC funding. There is no limit on the value of the grant, the value specified within the summary page is an example.

The Air Force Office of Scientific Research manages the basic research investment for the Department of the Air Force. Conferences and workshops constitute key forums for research and technology interchange. We provide partial support for conferences and workshops as defined in the DoW Joint Travel Regulations in special areas of science that bring experts together to discuss recent research or educational findings, or to expose other researchers or advanced graduate students to new research and educational techniques in our areas of research interest. Our research interests are described in the most recent version of our general Broad Agency Announcement titled, “Research Interests of the Air Force Office of Scientific Research” posted on Grants.gov. We can only consider funding requests from U.S. institutions of higher education (IHE) or nonprofit organizations as described in 2 CFR 200.1, including foreign public entities and foreign organizations operated primarily for scientific, educational, service, charitable, or similar purposes in the public interest. We do not award grants to organizations with a for-profit organization type. Our support for a workshop or conference is not an endorsement of any organization.

The  Chemical Oceanography  Program supports research into the chemistry of the oceans and the role of the oceans in global geochemical cycles. Areas of interest include chemical composition, speciation, and transformation; chemical exchanges between the oceans and other components of the Earth system; internal cycling in oceans, seas, and estuaries; and the use of measured chemical distributions as indicators of physical, biological, and geological processes.

The Research Infrastructure in the Social and Behavioral Sciences Program (RISBS) supports projects that create computational tools and data to facilitate basic research in the social and behavioral sciences that can lead to improved health, prosperity and security. Projects should be aimed at creating computational tools and data to enable research by social scientists. Examples include, but are not limited to, data collection or assembly efforts that result in new resources for a community of researchers or software platforms that facilitate data collection efforts by others. RISBS does not support research by PIs except in service of creation of the infrastructure. Innovation is especially encouraged. RISBS directly supports three key longitudinal surveys and panel studies that provide researchers with data on how American society functions and changes over time (and in 2010 were recognized as among the 60 most significant "discoveries or advances that... have had a large impact or influence on every American’s life... call[ed] the ‘Sensational 60’, in honor of NSF’s 60th anniversary”): The American National Election Study , which started in 1948 and has been funded by NSF since 1977, provides “gold standard” data on voting, public opinion, and political participation in U.S. national elections. The General Social Survey , a nationally representative interview survey of the U.S. adult population, collects data on a wide range of topics and has been funded by NSF since its inception in 1972. The Panel Study of Income Dynamics , a longitudinal survey of a nationally representative sample of U.S. families begun in 1968 (with NSF taking over most of its funding in 1980) collects data on a wide array of economic, social and health factors. The RISBS program administers separate solicitations for the American National Election Study (ANES), the General Social Survey (GSS) and the Panel Study of Income Dynamics (PSID). These solicitations have specific requirements and submission deadlines. Other infrastructure proposals may be submitted directly to the RISBS program at any time or transferred from other SBE programs following the respective program’s submission guidelines. RISBS also collaborates with other programs in the social and behavioral sciences through a co-funding process to support projects that create especially valuable tools for researchers in those fields or are furthering innovations in research infrastructure. Prospective PIs may also be interested in the Human Networks and Data Science Program — Infrastructure(HNDS-I) , which supports proposals addressing the development of data resources and relevant analytic techniques that support research in the social, behavioral and economic sciences.Prospective PIs are strongly encouraged to contact the RISBS program officers and/or program officers from other SBE programs that may be applicable to the proposal before submitting to RISBS and to refer to the NSF Proposal & Award Policies & Procedures Guide (PAPPG) policies on duplicate or substantially similar proposals.

The Cyberinfrastructure for Public Access and Open Science (CI PAOS) program within the Office of Advanced Cyberinfrastructure (OAC) aims to catalyze new and transformative socio-technical partnerships supporting research data infrastructure ecosystems across d omains through early-stage collaborative activities between cyberinfrastructure researchers, scie ntists , research computing experts, data management experts , research labs , university libraries , and other communities of practice. The CI PAOS program supports the NSF Public Access Initiative by encouraging innovation across the CI ecosystem t o address accessibility, discoverability, reliability, reproducibility, sustainability, and utility of data products in alignment with NSF and national goals for public access and open science [ See: NSF Public Access Initiative , Office of Science and Technology Policy Memorandum on Ensuring Free, Immediate, and equitable Access to Federally funded Research , and Desirable Characteristics of Data Repositories for Federally Funded Research ] . CI PAOS builds on previous investments including those through Dear Colleague Letters NSF 19-069 , NSF 20 -068 , NSF 23-018 , and the FAIROS R esearch C oordination N etworks ( RCN ) p rogram solicitation ( NSF 22-553 ) . NSF accepts proposals pursuant to this Program Description year-round. From time to time , NSF may also issue Dear Colleague Letters to encourage proposals on special thema tic interests and opportunities related to this progra m . GUIDANCE TO POTENTIAL PROPOSERS A primary feature of successful CI PAOS projects is a robust, synergistic collaborative team comprising skills from across communities of science/engineering, research data science, and information science discipline(s) and expertise in leveraging connections between cyberinfrastructure researchers and providers and data specialists . Leveraging international collaboration to build shared norms and address c hallenges related to developing and implementing PAOS policies and practices is encouraged . Research and education in science and engineering benefit immensely from international cooperation. P roposals with an international component are also welcome [See: International Collaborations Opportunities at NSF ] . Proposers must target one or more of th e following themes/pathways: Competency Building, Capability Building, and /or Community Building. Competency Building Open s cience /engineering-driven collaboration . A socio -technical collaborative approach in addressing disciplinary , interdisciplinary , domestic, and international data lifecycle challenges is critical to informing and guiding the development of principles, requirements , and standards of a CI ecosystem that fosters pipelines to good data management and pathways to access. Propos al s should clearly describe the goals, challenges, and rationale for the proposed data science and engineering project and include an explanation of the potential for transformative research and broader impacts on the open science ecosystem [ See: U.S. NSF Broader Impacts ] . Successful proposals will also clearly identify utilization science scenarios and use cases . C apability Building Exploratory and pilot activities. <span class="TextRun SCXW92189242 BCX4" lang="EN-US" xml:lang="EN-US" d

The Biomechanics and Mechanobiology (BMMB) program is part of the Mechanics of Materials cluster within the Division of Civil, Mechanical, and Manufacturing Innovation. The BMMB program supports fundamental and transformative research that advances our understanding of engineering biomechanics and/or mechanobiology. The program emphasizes the study of biological mechanics across multiple domains, from sub-cellular to whole organism. Distinct from conventional engineering materials, the program encourages the consideration of diverse living tissues as smart materials that are self-designing. BMMB projects must have a clear biological component, a clear mechanics component, and must improve our understanding of the mechanical behavior of a living system. Investigations of the mechanical behavior of biological molecules, cells, tissues, and living systems are welcome. An important concern is the influence of in vivo mechanical forces on cell and matrix biology in the histomorphogenesis, maintenance, regeneration, repair, and aging of tissues and organs. The program is also interested in efforts to translate recent biomechanical and mechanobiological discoveries into engineering science. Multiscale mechanics approaches are encouraged but not required. Projects may include theoretical, computational, or experimental approaches, or a combination thereof. NSF does not support clinical trials; however, feasibility studies involving human volunteers or animal subjects may be supported if appropriate to the scientific objectives of the project. Proposals should address the novelty and/or potentially transformative nature of the proposed work compared to previous work in the field. Also, it is essential to address why the proposed work is important in terms of engineering science, and to state the potential impact of success in the research on society and/or industry. Innovative proposals outside of these specific areas of biomechanics and mechanobiology will be considered. However, prior to submission of particularly unique topics, it is strongly recommended that Principal Investigators (PIs) contact the program director to discuss how the proposed work fits within the scope of the program and avoid the possibility of the proposal being returned without review. Related programs also fund certain aspects of biomechanics and mechanobiology research, and PIs are encouraged to examine these to find the appropriate program for submission. Proposals with a heavy emphasis on tissue engineering or developing validated models of tissue and organ systems should consider the Engineering of Biomedical Systems (EBMS) program.Projects addressing biological questions about the physiological mechanisms and structural features of organisms should consult the Physiological Mechanisms &amp; Biomechanics (PMB) program.Projects elucidating aspects of neural control may consider the Perception, Action, &amp; Cognition (PAC) program or the Mind, Machine, and Motor Nexus (M3X) program if the project contains work relevant to human-machine interaction. Projects in rehabilitation engineering should consider the Disability and Rehabilitation Engineering (DARE) program. Projects focused on fundamental research related to design, characterization, and modification of biomaterials should consider the Biomaterials (BMAT) program. Manufacturing systems proposals should consider the Advanced Manufacturing (AM) program. Work on the interplay between structure, dynamics, and function of biomolecules without advancing our understanding of the mechanics of a living system should consider the Molecular Biophysics program. Researchers who believe their work may span multiple programs are particularly encouraged to contact the cognizant program directors well in advance of submission. The duration of unsolicited proposal awards is generally up to three years; proposals for a shorter duration are welcome. Single-investigator award budgets typically include support for one graduate student (or equivalent trainee) and up to one month of PI time per year (awards for multiple investigator projects are typically larger). Proposal budgets or durations that are much larger than typical should be discussed with the program director prior to submission. Proposers can view budget amounts and other information from recent awards made by this program via the &ldquo;What Has Been Funded (Recent Awards Made Through This Program, with Abstracts)&rdquo; link towards the bottom of this page.

The objective of this Agreement is to advance historic preservation at the local level by establishing a task agreement between the National Park Service and the National Alliance of Preservation Commissions (NAPC) to provide training opportunities, promote the Federal Certified Local Government program, and strengthen local preservation commissions by providing bi-annual State Certified Local Government Coordinator Training

Anthropological research may be conducted under unusual circumstances, often in distant locations. As a result the ability to conduct potentially important research may hinge on factors that are impossible to assess from a distance and some projects with potentially great payoffs may face difficulties in securing funding. This program gives small awards that provide investigators with the opportunity to assess the feasibility of an anthropological research project. It is required that the proposed activity be clearly high risk in nature. The information gathered may then be used as the basis for preparing a more fully developed research program. Investigators must contact the cognizant NSF Program Director before submitting an HRRBAA proposal. This will facilitate determining whether the proposed work is appropriate for HRRBAA support.

Amendment 0007 The purpose of this amendment is to add Summary Topic 61-24-06 - AFFF ALTERNATIVE PROGRAM COMPATIBILITY OF FLUORINE-FREE FOAM (F3) WITH NON-ASPIRATING SPRINKLER NOZZLES to Appendix 1 in it’s entirety. All other terms and conditions remain unchanged. -------------------------------------------------------------- Amendment 0006 The purpose of this amendment is to extend the due date for acceptance of White Papers. All other terms and conditions remain unchanged. -------------------------------------------------------------- Amendment 0005 The purpose of this amendment is to provide a searchable list of Summary Topics contained in Appendix 1. Expanded descriptions of each topic can be found in the full announcement pdf. APPENDIX 1 – RESEARCH DESCRIPTION - SUMMARY TOPICS &nbsp; II. Detailed information about the funding opportunity &nbsp; The Naval Research Laboratory (NRL) is the Navy's corporate laboratory. NRL conducts basic and applied research for the Navy in a variety of scientific and technical disciplines. The basic research program is driven by perceptions about future requirements of the Navy. The Navy's operational effectiveness depends on its ability to keep pace with rapidly developing technologies. NRL contributes to this requirement by conducting research in the following areas, organized into NRL'S three research directorates and Naval Center for Space Technology: Systems Directorate Code 5000 Materials Science and Component Technology Directorate Code 6000 Ocean and Atmospheric Science and Technology Directorate Code 7000 Naval Center for Space Technology Code 8000 A.&nbsp;&nbsp;&nbsp;SYSTEMS DIRECTORATE - CODE 5000 53-24-01 - HIGH FREQUENCY RADAR 53-24-01C - HIGH FREQUENCY RADAR (CLASSIFIED) 53-24-02 - LOW-COST WIDEBAND ANTENNA ARRAY TECHNOLOGIES 53-24-03 - ADVANCED COMPUTATIONAL ELECTROMAGNETICS 55-24-01 - INFORMATION AND DECISION SCIENCES 55-24-02 - MATHEMATICAL FOUNDATIONS OF HIGH ASSURANCE COMPUTING 55-24-03 - HIGH ASSURANCE ENGINEERING AND COMPUTING 55-24-04 - ADVANCED NAVAL NETWORK SOLUTIONS 55-24-05 - FEDERATED, DISTRIBUTED COMPUTING/NETWORK INFRASTRUCTURE 56-24-01 - OPTICAL SCIENCES R&amp;D 57-24-01 &nbsp;- ELECTROMAGNETIC TECHNIQUES AND TECHNOLOGY RESEARCH AND DEVELOPMENT 57-24-02&nbsp;&nbsp;​ - SHIPBOARD ELECTRONIC WARFARE &nbsp; B.&nbsp;MATERIALS SCIENCE AND COMPONENT TECHNOLOGY DIRECTORATE CODE 6000 60-24-01 - HIGH PERFORMANCE COMPUTING ON MASSIVELY PARALLEL ARCHITECTURES 61-24-01 - ELECTROCHEMICAL ENERGY STORAGE, CONVERSION AND COMMAND/CONTROL 61-24-02 - CORROSION PROCESSES, CONTROL, MITIGATION, AND TECHNOLOGY 61-24-03 - APPLICATIONS OF MOLECULAR BIOLOGY, BIOCHEMISTRY, ANALYTICAL CHEMISTRY AND ADVANCED LASER TECHNIQUES 61-24-04 - MULTIECHELON DIAGNOSTICS (MEDx) TECHNOLOGY DEVELOPMENT AND TIERED EVALUATION 63-24-01 - MATERIALS PERFORMANCE, PROCESSING, AND MODELING 67-24-01 - BASIC AND APPLIED RESEARCH IN PLASMA SCIENCE 68-24-01 - RADIATION EFFECTS RESEARCH 68-24-02 - PHOTOVOLTAICS FOR PORTABLE POWER &nbsp; C.&nbsp;&nbsp;&nbsp;OCEAN AND ATMOSPHERIC SCIENCE AND TECHNOLOGY DIRECTORATE CODE 7000 71-24-01 - ACOUSTIC SIMULATION AND TACTICS 72-24-01 - LOW FREQUENCY RADIO INTERFEROMETRY 72-24-02 - OPTICAL REMOTE SENSING OF THE COASTAL REGIME 72-24-03 - REMOTE SENSORS AND IMAGING SYSTEMS 72-24-04 - AIRBORNE, SHIPBOARD, AND OVERHEAD DATA ACQUISITION AND ANALYSIS 73-24-01 - OCEAN DYNAMICS AND PREDICTION OCEANOGRAPHY 73-24-02 - SEAFLOOR SCIENCES 73-24-03 - GEOSPATIAL SCIENCES AND TECHNOLOGY 75-24-01 - ATMOSPHERIC EFFECTS, ANALYSIS, AND PREDICTION 76-24-01 - RESEARCH INTO SPACE, BACKGROUNDS, IMAGING AND MODELING &nbsp; D.&nbsp;&nbsp;&nbsp;NAVAL CENTER FOR SPACE TECHNOLOGY CODE 8000 82-24-01 - SPACECRAFT &amp; SPACE SYSTEMS TECHNOLOGY -------------------------------------------------------------- Amendment 0004 The purpose of this amendment is to extend the due date for acceptance of White Papers and revise Appendix 1 Summary Topics and email addresses in it’s entirety. -------------------------------------------------------------- Amendment 0003 The purpose of this amendment is to extend the due date for acceptance of White Papers.&nbsp;All other terms and conditions remain unchanged. ------------------------------------------------------------- Amendment 0002 The purpose of this amendment is to extend the due date for acceptance of White Papers.&nbsp;All other terms and conditions remain unchanged. ------------------------------------------------------------- Amendment 0001 The purpose of this amendment is to extend the due date for acceptance of White Papers.&nbsp;All other terms and conditions remain unchanged. -------------------------------------------------------------- The Naval Research Laboratory is interested in receiving innovative proposals that offer potential for advancement and improvement in the technical topic areas listed. This notice constitutes a Broad Agency Announcement (BAA) as contemplated in FAR 6.302(d) that provides for the competitive selection of research proposals. The Government reserves the right to select for award all, some, or none of the proposals received. Awards under this BAA are expected to take the form of Contracts, Grants, Cooperative Agreements and Other Transactions may also be awarded if appropriate. NRL encourages Educational Institutions, Small Businesses (SBs), Small Disadvantaged Business Concerns (SDBs) and Historically Black Colleges and Universities (HBCUs) and Minority Institutions (MIs) to submit proposals under this BAA. In order to conserve valuable offeror and Government resources, prospective offerors shall first submit a White Paper (WP) to the email address identified in the individual Summary Topics contained in Appendix 1, to include a rough cost estimate. If there is interest in the proposed research the offeror will be invited to submit a Formal Proposal.&nbsp;The selection of proposals for award will be based on a scientific review of proposals submitted in response to each BAA Summary Topic. The major purpose of the evaluation will be to determine the relative merit of the technical approach of each proposal. Business and contractual aspects, including proposed&nbsp;cost and cost realism, will also be considered as part of the evaluation. Selection of proposals for award will be based on the potential benefits to the Government weighed against the cost of the proposals, in view of the availability of funds. The complete BAA including proposal preparation instructions, award considerations, and evaluation criteria is also available at https://www.nrl.navy.mil/Doing-Business/Contracts/Broad-Agency-Announcements/ .

Scope: Air-to-air refuelling enhances military operations by enabling long-range missions. Refuelling currently requires manual coordination between tanker operators and receiving pilots, which is complex and labour-intensive. Automated air-to-air refuelling solutions are expected to reduce workload and increase safety for both crews, while also being essential for future unmanned aerial systems. The objective of this topic is to explore the development of sensor systems, in particular hardware and sensor fusion, to enable accurate relative navigation between tanker, receiver and refuelling systems, even in adverse conditions. In addition, enhanced optical sensors, advanced image processing, flight control algorithms and pilot assistance interfaces will play a crucial role in improving the docking and refuelling process, increasing safety and time efficiency. This topic contributes to the STEP objectives as defined in the STEP Regulation in the target investment area of defence technologies. Targeted types of activities: Integrating knowledge, studies and design, not excluding upstream activities eligible for research actions. Indicative budget: EUR 20 000 000 for this topic under…

Specific Challenge: The “EU Award for Gender Equality Champions” is a recognition prize scheme designed as a booster and a complement to the Gender Equality Plans (GEP) eligibility criterion in Horizon Europe [1] , and as a tool for advancing inclusive GEPs and policies within the framework of the ERA Policy Agenda. Expected Outcomes : Recognition of organisations with the most significant impact resulting from the implementation of their GEP, serving as role models for others; Strengthened gender equality and inclusiveness in the European Research Area. The Prize will be awarded to four organisations, and contestants can apply to one of the following three prize categories: Sustainable Gender Equality Champions: Organisations that can demonstrate a significant and sustained record of activity and a high level of achievement through the implementation of their GEP(s); Newcomer Gender Equality Champions: Organisations without a sustained record of activity in gender equality that have recently completed the implementation of their first GEP and can demonstrate the most progress achieved through its implementation; Inclusive Gender Equality Champions: Organisations that have…

Scope: The automatic analysis of tactical situations using fleets of robots, drones and AI is an important research topic that lacks standardised benchmarks and objective evaluation campaigns. This call topic aims to set up a testing environment and organise a technological challenge in which research teams will participate, supported by another topic (EDF-2024-LS-RA-CHALLENGE-DIGIT-AISAP-STEP) and possibly other sources of funding. The testing environment should enable objective comparisons between different approaches. Data should be collected during field tests, annotated and shared to enable the validation of the system performances based on precise evaluation criteria and plans, to be provided as part of the call document. Targeted types of activities: Integrating knowledge, not excluding upstream and downstream activities eligible for research actions. Indicative budget: EUR 7 000 000 for this topic under the EDF-2026-LS-RA-CHALLENGE call. Indicative number of proposals to be funded: One proposal is to be funded for this topic.

Specific Challenge: The “EU Award for Gender Equality Champions” is a recognition prize scheme designed as a booster and a complement to the Gender Equality Plans (GEP) eligibility criterion in Horizon Europe [1] , and as a tool for advancing inclusive GEPs and policies within the framework of the ERA Policy Agenda. Expected Outcomes : Recognition of organisations with the most significant impact resulting from the implementation of their GEP, serving as role models for others; Strengthened gender equality and inclusiveness in the European Research Area. The Prize will be awarded to four organisations, and contestants can apply to one of the following three prize categories: Sustainable Gender Equality Champions: Organisations that can demonstrate a significant and sustained record of activity and a high level of achievement through the implementation of their GEP(s); Newcomer Gender Equality Champions: Organisations without a sustained record of activity in gender equality that have recently completed the implementation of their first GEP and can demonstrate the most progress achieved through its implementation; Inclusive Gender Equality Champions: Organisations that have…

Scope: The proposals must demonstrate their disruptive impact on defence applications and address innovative technologies and solutions for defence, including those that can improve the readiness, deployability, reliability, safety and sustainability of forces in defence tasks and missions, for example in terms of operations, equipment, infrastructure, energy solutions, surveillance systems or digital solutions. Proposals must address disruptive knowledge, products and technologies in any area of defence interest (8 ) reaching at least TRL 4 (9 ).In addition, to best complement R&D efforts that already target civil applications and encourage the efficient spinning-in of knowledge, innovation and technological development to the defence sector, this topic also welcomes proposals for add-on research actions to adapt solutions originally developed for civilian applications and previously not applied in defence. Management mode : Action implemented in indirect management by the European Defence Agency. Targeted types of activities: Any activities eligible for a research action. However, proposals must not be limited to studies. Indicative budget: EUR 35 000 000 to support this…

Scope: The high speed and significant manoeuvrability of hypersonic vehicles, particularly hypersonic glide vehicles, create difficult conditions for target detection and tracking, which are exacerbated by changes in radar cross section characteristics. Radar waveforms and signal processing become essential to counter the effects induced by hypersonic threat dynamics. In addition, the last decade has seen a global increase in the use of unmanned aerial vehicles (UAVs) for battlefield intelligence gathering and reconnaissance. Anti-UAV radars therefore need to be developed to detect, identify and track such systems. Innovative approaches (e.g. AI and cognitive methods) can provide the means to select the best waveform receiver filter combination to maximise radar detection and tracking performance also using a feedback loop between the received and transmitted signal characteristics. This topic therefore focuses on the development of an engineering development model (i.e. demonstrator) capable of supporting tasks such as demonstrating the maturity of innovative technologies in the radar domain and supporting the feasibility of implementing such technologies in terms of time,…

Scope: This topic aims to improve the protection of seabed infrastructure through a comprehensive system, including unmanned assets, advanced sensors, underwater observation, detection, acquisition and communication systems, and integrated command and control. This initiative focuses on the development and validation of such a system for future operations, integrated with maritime command centres for coordinated responses. The approach combines operational levels and innovative technologies to effectively mitigate risk and ensure continuity of operations. Beyond defence technologies, this topic also contributes to the STEP objectives as defined in the STEP Regulation in the target investment area of deep and digital technologies. Targeted types of activities: Studies and design, not excluding upstream activities eligible for research actions. Indicative budget: EUR 30 000 000 for this topic under the EDF-2026-RA-SI call. Range of financial contribution of the EU per proposal : The requested funding cannot exceed EUR 15 000 000. The proposals need to build upon or integrate results that have been achieved within one or several projects funded following an EU programme call with a…

Scope: There is a need for a new multirole light aircraft that can bridge the gap between today’s battlefield and modern technology, as most of the fleet in this segment across the EU is ageing. The future multirole light aircraft (FMLA) concept must not duplicate or create fragmentation of existing systems of turboprop and tactical military transport aircraft and associated electronic systems. By exploiting the existing platforms, technologies and innovations in Europe, this research topic can reduce the risks associated with the development of FMLA capabilities for air-to-ground operations. FMLA should also be effective in specific combat roles such as light attack, anti-drone interception and close air support. The objective of this topic is therefore to develop a low-cost, single-engine (turboprop) aircraft capable of operating in a variety of operational environments, providing direct air support, ground targeting, intelligence, surveillance and reconnaissance with combat elements, and air strike coordination and reconnaissance with air traffic control support in a forward position in hostile environments during counter-terrorism missions. This topic contributes to the STEP…

Scope: Assisting soldiers with robots and drones that can provide accurate tactical situational awareness by using AI becomes essential for soldier protection. This call topic aims to follow on and complement previous activities in the field of hidden threat detection and explore solutions involving various combinations of intelligent robots, drones and sensing technologies for advanced detection and recognition of threats, in view of their avoidance or neutralisation. These solutions should be tested under realistic scenarios in a comparable and objective manner to reach up to Technical Readiness Level (TRL) 6. For that purpose, each consortium supported through this call topic will benefit from a common testing environment set up as part of a technological challenge and will have to participate in the experiment campaigns organised with this objective. Beyond defence technologies, this topic also contributes to the STEP objectives as defined in the STEP Regulation in the target investment area of deep and digital technologies. Targeted types of activities: Generating knowledge, not excluding upstream and downstream activities eligible for research actions. Indicative budget: EUR…

Specific Challenge: The “EU Award for Gender Equality Champions” is a recognition prize scheme designed as a booster and a complement to the Gender Equality Plans (GEP) eligibility criterion in Horizon Europe [1] , and as a tool for advancing inclusive GEPs and policies within the framework of the ERA Policy Agenda. Expected Outcomes : Recognition of organisations with the most significant impact resulting from the implementation of their GEP, serving as role models for others; Strengthened gender equality and inclusiveness in the European Research Area. The Prize will be awarded to four organisations, and contestants can apply to one of the following three prize categories: Sustainable Gender Equality Champions: Organisations that can demonstrate a significant and sustained record of activity and a high level of achievement through the implementation of their GEP(s); Newcomer Gender Equality Champions: Organisations without a sustained record of activity in gender equality that have recently completed the implementation of their first GEP and can demonstrate the most progress achieved through its implementation; Inclusive Gender Equality Champions: Organisations that have…

Expected Outcome: At a general level, the project should achieve a strong, visible and recognised impact in scaling, facilitating and accelerating research and analytical efforts focussing on the information environment and information integrity. The main outcomes of the awarded project will be: The technical solutions created or supported The insights generated from supported research and monitoring projects The proof of concept and lessons learnt for the support of shared infrastructures to support research on the information environment Project applications will formulate their own deliverables in accordance with their needs analyses and proposed means to address them. At the minimum, deliverables should include: A suite or network of solutions capable of addressing Specific Objectives 1 and 2 (c.f. section 2 ‘Scope – Specific Objectives 1 and 2’) A methodology and dissemination plan for creating access to the created resources (c.f. section 2 ‘Scope – Specific Objective 3) A sub-granting methodology in line with the scope set forth in the section above (c.f. section 2 ‘Scope – Specific Objective 5’) A final report detailing lessons learnt and identifying clear paths for future…

Scope: The next generation of tactical military networks are being developed using software defined radio solutions and software defined network solutions to provide secure and resilient communications against cyberattacks. More agile and flexible than traditional approaches, these solutions make it much easier to integrate additional devices, including mobile devices, and innovative technologies into military networks such as quantum key distribution, post-quantum cryptography and physical unclonable functions. In particular, quantum key distribution aims to provide a higher level of trust in information sharing and cyber defence operations by ensuring that all intrusions and hacking attempts are detected in real time using quantum principles. Building on previous and ongoing EDF R&D activities in this area, this topic aims to develop software defined network technologies and solutions for a network architecture framework based on quantum technologies that will provide EU armed forces with a technological edge in secure tactical networks. Beyond defence technologies, this topic also contributes to the STEP objectives as defined in the STEP Regulation in the target investment area…

Scope: Current military decontamination processes are manual and time-consuming, while automation could improve efficiency, safety and control. Clearance decontamination, which ensures that equipment is safe for transport and disposal, is a challenging process that may require advanced technologies. A new approach to CBRN decontamination is needed that is simple, safe, reliable and uses minimal water. New technologies such as catalysts and UV radiation are being considered to neutralise agents without damaging equipment. Decontamination is also critical in the management of biological emergencies, including epidemics and pandemics, and is not limited to military scenarios. Solid sorbents, including nanosorbents, are promising, with advantages such as low toxicity and non-corrosiveness. Clearance decontamination should conform to nationally established standards and guidelines so that the equipment can be transported through non-EU countries and/or returned to its country of origin or final destination. This topic aims to explore solutions for the thorough decontamination of large military equipment, in particular for post-mission decontamination. It focuses on the development of…

Scope: Objectives The Starting Grant supports excellent Principal Investigators starting or having recently started their own independent research team or programme. A Starting Grant Principal Investigator should have already shown evidence of the potential for research independence, for example, by having produced at least one important publication as its main author or a publication without the participation of their PhD supervisor. A researcher may be the Principal Investigator of only one ERC Starting Grant in their career. Size of ERC Starting Grants Starting Grants may be awarded up to a maximum of EUR 1 500 000 for a period of 60 months . The maximum amount of the grants is reduced pro rata temporis for proposals of shorter duration. Additional funding up to EUR 1 000 000 *1 can be requested to cover further eligible costs for any cost category when these are necessary to carry out the proposed work. The request for additional funding must be duly justified in the proposal. The maximum amount of the grant is reduced pro rata temporis for proposals of shorter duration. Additional funding is not subject to pro rata temporis reduction for projects of shorter duration. Both the…

Objective: The objective of this call is to modernise transport infrastructure and enhance the digitalisation of road transport on the TEN-T network. Scope: Works related to: Projects fostering the deployment of new technologies and innovation by supporting test-beds / infrastructure for autonomous vehicles [1]. The focus will be specifically on investments in infrastructure for commercial (pre-) deployment of autonomous vehicles, implementing sufficiently mature technology that do not include Research & Innovation activities. The projects to be financed shall contribute to the deployment of highly automated vehicles on the road for real operation, requiring investment in infrastructure to ensure the efficient operation of autonomous vehicles, in two areas: Establishing control centers (IT equipment for remote supervision of highly automated vehicles, offering support in challenging or unexpected situations). Support is not provided to the construction of actual buildings (such as TMC building). Deploying digital infrastructure for accurate vehicle positioning and communication with the surrounding environment (including interaction with emergency services). Particular attention…

Expected Impact: Accompanying measures are expected to ensure a balanced representation, within the consortium, of relevant academia, research centres, industry and/or industry associations, including just transition actors. They should also involve stakeholders required for the just transition of coal regions. In addition, accompanying measures may provide suggestions for policy initiatives that contribute to the digital, green and circular transformation of the coal communities, in line with the European Green Deal. Objective: Proposals submitted under this topic should relate to one or more of the RFCS objectives for coal, as set out in Council Decision 2008/376/EC . Scope: Accompanying measures aim to promote the use of knowledge gained or the organisation of dedicated workshops or conferences in connection with projects or priorities of the RFCS.

Expected Impact: Each proposal must include an assessment of the expected industrial, economic, social and environmental benefits (Article 26 of Council Decision 2008/376/EC). Objective: Proposals submitted under this topic should relate to one or more of the RFCS objectives for steel as set out in Council Decision 2008/376/EC . Scope: Research projects focus on investigative or experimental work aiming to acquire knowledge to facilitate the attainment of specific practical objectives. Research project activities are expected to start at TRL 1-3 and achieve TRL 4-5 by the end of the project.

Expected Impact: Each proposal must include an assessment of the expected industrial, economic, social and environmental benefits (Article 26 of Council Decision 2008/376/EC). Objective: Proposals submitted under this topic should relate to one or more of the RFCS objectives for coal as set out in Council Decision 2008/376/EC . Scope: Pilot projects target the construction, operation and development of installations on an appropriate scale. Demonstration projects cover the construction and/or operation of industrial-scale installations.Both pilot and demonstration projects aim to bridge the gap between research and innovation. Pilot and demonstration activities are expected to start at TRL 4-5 and achieve TRL 7-8 by the end of the project.

Scope: This topic aims to improve the design of underwater platforms and the proper integration of sonars, including the verification of existing tools and the development of better tools for modelling underwater flow-generated noise that can support the placement of sonars and the simulation of radiated noise from underwater platforms. The models to be developed for both sonar design and radiated noise will include the generation of high-quality verification data and would support the design of underwater platforms and the placement and design of sonars. Targeted types of activities: Generating knowledge, integrating knowledge and studies, not excluding downstream activities eligible for research actions. Indicative budget: EUR 10 000 000 for this topic under the EDF-2026-RA call. Indicative number of proposals to be funded: One proposal is to be funded for this topic. However, depending on the quality of the proposals submitted and the budget available, more than one proposal may ultimately be funded for this topic.

Expected Impact: Accompanying measures are expected to ensure balanced representation, within the consortium, of relevant academia, research centres, industry and/or industry associations, including just transition actors. They should also involve stakeholders required for the just transition of the steel industry. In addition, accompanying measures may provide suggestions for policy initiatives that contribute to the digital, green and circular transformation of steel communities, in line with the European Green Deal. Objective: Proposals submitted under this topic should relate to one or more of the RFCS objectives for steel as set out in Council Decision 2008/376/EC . Scope: Accompanying measures aim to promote the use of knowledge gained or the organisation of dedicated workshops or conferences in connection with projects or priorities of the RFCS.

Expected Impact: Each proposal must include an assessment of the expected industrial, economic, social and environmental benefits (Article 26 of Council Decision 2008/376/EC). Objective: Proposals submitted under this topic should relate to one or more of the RFCS objectives for steel as set out in Council Decision 2008/376/EC . Scope: Pilot projects target the construction, operation and development of installations on an appropriate scale. Demonstration projects cover the construction and/or operation of industrial-scale installations. Both pilot and demonstration projects aim to bridge the gap between research and innovation and commercialisation. Pilot and demonstration activities are expected to start at TRL 4-5 and achieve TRL 7-8 by the end of the project.

Expected Impact: Each proposal must include an assessment of the expected industrial, economic, social and environmental benefits (Article 26 of Council Decision 2008/376/EC). Objective: Proposals presented under this topic should relate to one or more of the RFCS objectives for coal as set out in Council Decision 2008/376/EC . Scope: Research projects focus on investigative or experimental work aiming to acquire knowledge to facilitate the attainment of specific practical objectives.Research project activities are expected to start at technology readiness level (TRL) 1-3 and achieve TRL 4-5 by the end of the project.

Summary: The fiscal year 2026 (FY26) Pancreatic Cancer Research Program (PCARP) Focused Pilot Award supports the exploration and development of impactful and innovative concepts under a patient-centered focus area of pancreatic cancer research that could ultimately lead to major advancements that will have a profound effect on patients’ overall quality of life. The research this award supports should strive to produce robust preliminary data that can serve as a foundation for future clinical or real-world research application. Distinctive Features: This award mechanism allows, but does not require, preliminary data. Applications can support clinical research studies; however, this mechanism does not allow clinical trials. Preclinical animal studies do not meet the intent of this mechanism.

Summary: The fiscal year 2026 (FY26) Traumatic Brain Injury and Psychological Health Research Program (TBIPHRP) Health Services Research Award (HSRA) intends to fund high-impact research that bridges the gap between research, practice and policy by building real-world evidence on how interventions, clinical practices/guidelines, or policies can be deployed to targeted populations at the appropriate time. In order to meet this intent, the mechanism supports health services research approaches. Distinctive Features: ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The HSRA will support health services research approaches that include comparative effectiveness research; implementation of interventions, diagnostics and clinical practices/guidelines; and validation of data science insights. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Applications must include clinical research or clinical trials . Prospective or retrospective clinical research or clinical trials involving human subjects, human subject data/records, and human anatomical substances are allowed. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Preliminary data are required. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Basic, preclinical and animal research are prohibited. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;For research prospectively enrolling human subjects, inclusion of community-based participatory research (CBPR) approaches is required. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Early-Career Investigator Partnering Option : This option accommodates two Principal Investigators (PIs), one of which is an Early-Career Investigator. If recommended for funding, each PI will receive a separate award.

Summary: The fiscal year 2026 (FY26) Traumatic Brain Injury and Psychological Health Research Program (TBIPHRP) Clinical Trial Award (CTA) intends to support clinical trials with the potential to have a significant impact on psychological health conditions and/or traumatic brain injury (TBI) through clinical applications, including health care products, technologies and/or practice guidelines. &nbsp; Distinctive Features: Funding from this award mechanism must support a clinical trial. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Clinical trials may be designed to evaluate a wide range of interventions, including new drugs, biologics, medical devices, diagnostics, therapies and behavioral health strategies. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Preliminary data are required. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The inclusion of community-based participatory research (CBPR) approaches is required. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The CTA offers funding for two Research Levels. The applicant is responsible for selecting the Research Level based on the scope of the research. ○&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Research Level 1: Supports proof-of-principle pilot studies, as well as phase 1 and phase 2 clinical trials. ○&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Research Level 2: Supports larger-scale and advanced clinical trials that evaluate effectiveness in relevant patient populations. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Early-Career Investigator Partnering Option ( available for both Research Levels ): This option accommodates two Principal Investigators (PIs), one of which is an Early-Career Investigator. If recommended for funding, each PI will receive a separate award.&nbsp;

Summary: The fiscal year 2026 (FY26) Pancreatic Cancer Research Program (PCARP) Idea Development Award supports the development of innovative, high-risk/high-reward research that could lead to critical discoveries or major advancements that will accelerate progress in improving outcomes for individuals with pancreatic cancer. This award mechanism supports innovative ideas with the potential to yield impactful data and new avenues of investigation. All applications must address at least one of the FY26 PCARP Focus Areas . Distinctive Features: This award mechanism requires preliminary data relevant to the proposed project. Applications can support clinical research studies; however, this mechanism does not allow clinical trials. Partnering Principal Investigator (PI) Option for Early-Career Investigator: This funding mechanism offers a higher level of funding for applications that propose to partner an experienced PI (i.e., Initiating PI, who will serve as the mentor) with an Early-Career Investigator (i.e., Partnering PI) wishing to pursue a career in pancreatic cancer research. For this option, only the Initiating PI will submit a pre-application, but both PIs will need to submit at the full application stage. The partnering PI’s application is an abbreviated package specific to their distinct portion of the research project. Be advised, all associated applications for a research project may be withdrawn if the initiating or partnering application is rejected or administratively withdrawn.

Summary: The fiscal year 2026 (FY26) Peer Reviewed Cancer Research Program (PRCRP) Clinical Trial Award (CTA) supports the rapid implementation of clinical trials with the potential to have a significant impact on the treatment or management of cancer within at least one of the FY26 PRCRP Topic Areas. Clinical trials proposed may evaluate promising new products, pharmacologic agents (drugs or biologics), devices, clinical guidance, and/or emerging approaches and technologies. Proposed projects may range from small proof-of-concept trials (e.g., pilot, first-in-human, phase 0) that evaluate the effects of interventions or inform the design of more advanced trials to large-scale trials (up to phase III) to determine efficacy in relevant patient populations. Distinctive Features: • Applications to this award mechanism must include a clinical trial. • Projects can range from phase 0 to phase III. • If an Investigational New Drug (IND) application, Investigational Device Exemption (IDE), or equivalent, is required, a regulatory application must be submitted to the relevant regulatory agency by the Clinical Trial Award application submission deadline. The regulatory application should be specific to the product and indication to be tested in the proposed clinical trial. • Applications are required to include patient advocates. • Animal studies are NOT allowed under this award mechanism. All preclinical work must be completed prior to the award start date.

Summary: The fiscal year 2026 (FY26) Melanoma Research Program (MRP) Idea Award supports innovative, exploratory, high-risk/potentially high-reward research. Novelty and innovation are expected to be key aspects of the proposed project. By the end of the Idea Award funding period, the anticipated outcomes of successful efforts should establish proof of principle and obtain preliminary data to secure follow-on funding. Distinctive Features: • Preliminary data are discouraged. • After submitting the required pre-application, investigators must receive an invitation to submit a full application.

Summary: The Translational Research Award (TRA) intends to accelerate the conversion of scientific findings into impactful clinical applications. The TRA prioritizes innovative approaches over purely iterative or incremental research. Submissions focusing on minor modifications to existing standards without the intent or potential to significantly improve clinical care or patient outcomes do not meet the intent of the mechanism. Distinctive Features: Basic research and clinical trials are prohibited. Preliminary data are required. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;For animal research, applications must describe the choice of model and its relevance to the human clinical condition. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;For research prospectively enrolling human subjects, the inclusion of community-based participatory research (CBPR) approaches is required. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The Translational Research Award offers funding for two Research Levels. The applicant is responsible for selecting the Research Level based on the scope of the research. ○&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Research Level 1: Supports the refinement of mature ideas and concepts into tangible and knowledge products positioned for further evaluation. ○&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Research Level 2: Supports the rigorous evaluation of tangible and knowledge products in preparation for first-in-human studies or clinical trials. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Early-Career Investigator Partnering Option ( available for both Research Levels ): This option accommodates two Principal Investigators (PIs), one of which is an Early-Career Investigator. If recommended for funding, each PI will receive a separate award.&nbsp;

Summary: The fiscal year 2026 (FY26) Melanoma Research Program (MRP) Focused Program Award – Rare Melanomas, supports a multidisciplinary research program of at least two, but not more than three, distinct but complementary research projects addressing an overarching question relevant to rare melanomas. Distinctive Features: ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; *Updated for FY26* Investigators must include at least one rare melanoma survivor or patient advocate as part of the project team who will provide advice and consultation throughout planning, implementation, and results dissemination to maximize research impact. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; This is a partnering mechanism, requiring an Initiating Principal Investigator (PI) and at least one, but not more than two, Partnering PIs, see Figure 1 . &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Each named PI is expected to be a Project Leader for one of the proposed research projects. If recommended for funding, each PI will be named on separate awards to the recipient organization(s). ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;After submitting the required pre-application, investigators must receive an invitation to submit a full application . &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Only the Initiating PI will submit a pre-application. All PIs must submit full applications. The Partnering PI(s)’s application is an abbreviated package specific to their proposed research project. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Clinical trials are allowed.

Summary: The fiscal year 2026 (FY26) Melanoma Research Program (MRP) Team Science Award supports a broad range of hypothesis-driven, multidisciplinary studies that have a short-term goal of advancing the state of the science in melanoma research and/or patient care. Team science is a synergistic effort that harnesses techniques, approaches and perspectives from multiple disciplines and/or therapeutic areas to address complex, multi-dimensional problems that will impact patient outcomes. Distinctive Features: ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;This funding mechanism requires multiple Principal Investigators (PIs). At least two and up to three PIs should partner to jointly design and execute a single research project ; multi-institutional partnerships are encouraged. If recommended for funding, each PI will be named on separate awards to the recipient organization(s). ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Consumer Collaboration Option: Investigators are encouraged, but not required, to form collaborative relationships with the melanoma consumer community to maximize the impact and translatability of the research for the benefit of the intended community(ies). ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;After submitting the required pre-application, investigators must receive an invitation to submit a full application . &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Only the Initiating PI will submit a pre-application. All PIs must submit full applications. The Partnering PI(s)’s application is an abbreviated package specific to their proposed research effort.

Summary: The fiscal year 2026 (FY26) Melanoma Research Program (MRP) Survivorship Research Award addresses the relatively new and underfunded area of melanoma-specific survivorship by supporting a broad range of innovative and impactful research that has the intended outcome of improving the health and well-being of melanoma survivors, their families and/or their care partners in the near term. Proposed studies focusing exclusively on animal models or considering survival only without consideration of quality of life, overall health and/or function are not responsive to this funding opportunity. Distinctive Features: ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The application must include at least one melanoma consumer collaborator , defined as a melanoma survivor, family member and/or care partner who can provide lived experience expertise to the research project team, or a melanoma-community supporting organization to support the planning, execution, and implementation of the proposed research. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Clinical trials are allowed.

Summary: The fiscal year 2026 (FY26) Peer Reviewed Cancer Research Program (PRCRP) Impact Award supports mature research that will have a near-term impact on clinical cancer care in one of the congressionally directed FY26 PRCRP Topic Areas. Applicants must consider how the research project will lead to the advancement of knowledge in cancer research, patient care and/or treatment options in the Military Health System (MHS). Distinctive Features: • Applications must include preliminary data to support feasibility of the study. • Projects must have strong potential to result in a near-term impact in cancer. • The funding mechanism allows clinical trials. • This funding mechanism allows for a single Principal Investigator (PI), or two partnering PIs referred to as the Initiating PI and the Partnering PI. Only the Initiating PI will submit a pre-application, but both PIs will need to submit full applications. The Partnering PI’s application is an abbreviated package specific to their distinct portion of the research project. Be advised, both applications for a research project may be withdrawn if the initiating or partnering application is rejected or administratively withdrawn.

Summary: The fiscal year 2026 (FY26) Peer Reviewed Cancer Research Program (PRCRP) Idea Award (IA) supports innovative, untested, high-risk/potentially high-reward concepts, theories, paradigms, and/or basic cancer research. The advancement of knowledge in cancer research, patient care, and/or treatment options in the Military Health System (MHS) is critical to Service Members, Veterans, other military beneficiaries and the American public. Distinctive Features: The proposed project should demonstrate creative thinking and innovation. • Incremental advances, the next logical step, or switching a model system from one cancer to another cancer are not appropriate for this award. • Inclusion of preliminary data is not required; however, the project must be based on strong scientific rationale. • New for FY26: Early Career Investigator Option: The Early Career Investigator option is designed to support the continued development of promising independent investigators that are early in their faculty appointments.

Summary: Supports the addition of independent, early career investigators (Scholars) who are no more than seven years from their initial faculty appointment to the Melanoma Research Program (MRP) Melanoma Academy. The Melanoma Academy is a unique, interactive virtual academy focused on bringing together established investigators and Scholars to develop a network of successful, highly productive melanoma researchers in a collaborative research and career development environment. Distinctive Features: This award mechanism focuses on both the Scholar’s research and career potential in the melanoma field. Scholars must designate a Career Guide. The Career Guide must have a track record of successful mentorship coupled with a strong record of funding and publications in melanoma. Preliminary data are not required.

The Mathematical Biology Program supports research in all areas of mathematical sciences with relevance to the biological sciences. Successful proposals must demonstrate mathematical innovation, biological relevance and significance, and strong integration between mathematics and biology. Some projects of interest to the Mathematical Biology Program may include development of mathematical theories, methodologies, and tools traditionally seen in other disciplinary programs within the Division of Mathematical Sciences. In general, if a proposal is appropriate for review by more than one NSF program, it is advisable to contact the program officers handling each program to determine when and where the proposal should be submitted and to facilitate the review process. The Mathematical Biology Program regularly seeks joint reviews of proposals with programs in the Directorates of Biological Sciences and other relevant programs. Investigators are encouraged to discuss their project with program officers in relevant areas to determine whether it could be considered by more than one program. Research in Undergraduate Institutions (RUI) Investigators submitting an RUI proposal should read the RUI solicitation (link below), as the rules for proposal format may deviate from the Proposal &amp; Award Policies &amp; Procedures Guide (PAPPG). EAGER and RAPID Proposals Prior to submitting proposals for EArly-concept Grants for Exploratory Research (EAGER) or Rapid Response Research (RAPID), Investigators must contact the cognizant program directors. Requests for Award Supplements Principal Investigatorsare encouraged to contact the cognizant program director prior to submission of a proposal for an award supplement. See the PAPPG for more information. Conferences Investigators should carefully read the program solicitation, "Conferences and Workshops in the Mathematical Sciences," (link below) to obtain important information regarding the substance of proposals for conferences, workshops, summer/winter schools, and similar activities. To facilitate timely notification of the availability of support: proposals for conferences, workshops, etc., to be held in the US must be submitted 8 months in advance of the conference date; proposals to support group travel to meetings outside the US must be submitted 12 months in advance of the meeting date.

The Algebra and Number Theory program supports research in algebra, algebraic and arithmetic geometry, number theory, and representation theory. Conference proposals The Algebra and Number Theory program also provides support for conferences, workshops, summer/winter schools, and similar activities. Proposals should be submitted to PD 20-1264 using the "Conference" proposal type in research.gov. Proposals with budgets not exceeding $50,000, which in accordance with NSF policy can be reviewed internally, should be submitted: in May for events that will take place in January through April of the following year in October for events that will take place in May through December of the following year. In order to allow time for external review, proposals with budget requests exceeding $50,000 should be submitted nine to twelve months before the event is scheduled to take place.

Summary: The fiscal year 2026 (FY26) Pancreatic Cancer Research Program (PCARP) Translational Research Partnership Award supports partnerships between clinicians, population scientists, applied scientists and/or basic scientists that will accelerate the movement of promising ideas in pancreatic cancer toward clinical applications. The partnership must include at least one member with expertise in pancreatic cancer research or pancreatic cancer patient care. All applications must address at least one of the FY26 PCARP Focus Areas . ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;This award mechanism requires preliminary data to support feasibility of the research hypothesis(es) and research approaches. However, these data do not necessarily need to originate from studies of pancreatic cancer. Applications can support retrospective tissue analysis, correlative studies and pilot clinical trials; however, this mechanism does not allow large-scale clinical trials. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The Translational Research Partnership Award requires two Principal Investigators (PIs) referred to as the Initiating PI and the Partnering PI . Only the Initiating PI will submit a pre-application, but both PIs will need to submit at the full application stage. The partnering PI’s application is an abbreviated package specific to their distinct portion of the research project. Be advised, all associated applications for a research project may be withdrawn if the initiating or partnering application is rejected or administratively withdrawn.

Summary: The fiscal year 2026 (FY26) Amyotrophic Lateral Sclerosis Research Program (ALSRP) Therapeutic Idea Award (TIA) supports new, innovative, high-risk, high-gain ideas aimed at amyotrophic lateral sclerosis (ALS) drug or therapy discovery. The studies supported by this award mechanism are expected to be hypothesis-driven and generate preliminary data for future avenues of therapeutic investigation. Distinctive Features: Potential impact and innovation are important features of the TIA. Applications may demonstrate the ability to achieve interpretable results in the absence of preliminary data supporting the hypothesis. While the inclusion of preliminary data is not prohibited, the strength of the application should rely on the approach.

Summary: The fiscal year 2026 (FY26) Autism Research Program (ARP) Clinical Trial Award supports the rapid implementation of clinical trials with the potential to have a significant impact on the treatment or management of autism. Clinical trials may be designed to evaluate promising new products, pharmacologic agents (drugs or biologics), devices, clinical guidance and/or emerging approaches and technologies. Proposed projects may range from small proof-of-concept trials (e.g., pilot, first-in-human, phase 0) to demonstrate the feasibility or inform the design of more advanced trials through large-scale trials to determine efficacy in relevant patient populations. Distinctive Features: Applications are strongly encouraged to address one of the FY26 ARP Clinical Trial Award Areas of Interest. Partnering Principal Investigator (PI) Option for Early-Career Investigator: The FY26 Clinical Trial Award mechanism is offering a higher level of funding for applications that propose to partner an experienced PI (i.e., Initiating PI) with an Early-Career Investigator (i.e., Partnering PI) wishing to pursue a career in autism clinical trial research. FY26 Clinical Trial Award submissions are required to include community collaborations to optimize research impact. Research teams are therefore required to establish and utilize effective and equitable collaborations and partnerships with community members to maximize the translational and impact potential of the proposed research. Applications to the FY26 ARP Clinical Trial Award are expected to name at least one community partner (e.g., Autistic individual or caregiver, representatives of community-based organizations) who will provide advice and consultation throughout the planning and implementation of the research project. Interactions with other team members should be well integrated and ongoing, not limited to attending seminars and semi-annual meetings (see Attachment 12, Community Collaboration Plan).

Summary: The fiscal year 2026 (FY26) Rare Cancers Research Program (RCRP) Concept Award (CA) supports highly innovative, untested, potentially groundbreaking novel concepts in rare cancers. Applications must describe how the new idea will be innovative and present as a novel course of investigation in the field of rare cancers. Distinctive Features: Preliminary data are not required. Due to the blinded nature of the review process, identifying or making references to the Principal Investigator (PI), collaborator(s), or their organization(s) in the proposal Project Narrative, Supporting Documentations, Impact Statement, Justification Statement, and Statement of Work (SOW) is prohibited and will result in administrative rejection of the application.

Summary: Initially created in fiscal year 2019 (FY19), the Kidney Cancer Research Program (KCRP) Academy of Kidney Cancer Investigators (AKCI) is a unique interactive virtual academy providing intensive mentoring, national networking, collaborations, and a peer group for junior faculty. The Academy pairs Early Career Scholars (ECS) with established investigators (Designated Mentors) under the oversight of the AKCI Leadership Team, a Designated Mentor Panel, and the Kidney Cancer Patient Advocates Panel. The AKCI’s overarching goal is to conduct innovative and impactful kidney cancer research while also developing a vital resource, a network of highly productive kidney cancer researchers conducting cutting edge research that advances the state of the field in kidney cancer and leads to new treatments for individuals living with kidney cancer. Distinctive Features: ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Early-Career Scholar: The FY26 KCRP AKCI-ECSA focuses on both the Scholar’s research and their career potential in the kidney cancer field. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Designated Mentor: The Designated Mentor must have a strong record of successful mentorship coupled with a strong record of funding (past and present) and publications in kidney cancer research. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Preliminary Data: Preliminary data to support the feasibility of the research and approaches are required; however, these data do not need to be derived from the kidney cancer research field.

Summary: The fiscal year 2026 (FY26) Alzheimer’s Research Program (AZRP) Transforming Research Award (TrRA) supports non-incremental, robust, well-designed research that drives transformative advancements in reducing risk and preventing the development of Alzheimer’s disease and/or Alzheimer's disease related dementias (AD/ADRD). Distinctive Features: • Applications must address at least one of the following focus areas: ○ Risk Factor Knowledge: Research that advances understanding, identification, and/or validation of risk and/or protective factors, with research outcomes/products focused on accelerating solutions. Projects may include, but are not limited to, research on environmental, epigenetic, genetic, lifestyle, occupational, or other risks not listed here. ○ Risk Reduction Solutions: Research that describes methods, technologies, and strategies that contribute to reducing risk and preventing AD/ADRD. • Clinical research is allowed, however clinical trials and animal research are prohibited. • Preliminary data are required. • Community collaboration is required for research prospectively enrolling human subjects. • Career Initiation or Transition (CIT) Partnership Option: The TrRA includes an option for more than one PI and supports both new and existing collaborative partnerships. If recommended for funding, each PI will be named on separate awards to the recipient organization(s). If utilizing this option, at least one independent investigator must meet

Summary: The fiscal year 2026 (FY26) Arthritis Research Program (ATRP) Translational Research Award (TRA) supports high-impact translational research that will accelerate critical findings into clinically relevant solutions. Research funded under this award mechanism will be hypothesis-driven, high-impact applied research that is relevant to Service Members, Veterans, their Families and the American public. Research addressing any and all types of arthritis is encouraged. Distinctive Features: The FY26 ATRP TRA mechanism is intended to support preclinical or animal research and may not be used for clinical research or clinical trials. Basic research, as defined in Section 3.1.2, is not allowed. A key aspect of this award mechanism is impact. The application should explicitly state how outcomes of the proposed research will significantly advance arthritis research, particularly in accelerating critical findings into clinically relevant solutions. Preliminary and/or published data, originating from research conducted by the applicant(s) or others, is required.

Summary: The intent of the fiscal year 2026 (FY26) Tick-Borne Disease Research Program (TBDRP) Idea Development Award (IDA) is to support conceptually innovative research that could lead to impactful discoveries or significant advancements that will accelerate progress toward reducing the burden of Lyme disease and/or other tick-borne diseases and conditions, and improving patient care and/or the quality of life. Applications should propose research that is conceptually innovative, introduces a new concept or question, challenges existing paradigms, approaches issues from a new perspective, or exhibits other uniquely creative qualities; and should not merely be a next logical step or an incremental advance on published data or ongoing research. Distinctive Features: A Career Development Option is available to eligible early-career investigators who propose to conduct impactful mechanism-relevant research under the mentorship of an experienced tick-borne disease researcher(s). Applications submitted under the IDA – Career Development Option (IDA-CDO) will be reviewed using separate, career development-specific evaluation criteria by a separate, dedicated peer review panel; and are subject to a lower cost limit than those submitted under the standard IDA. https://cdmrp.health.mil/pubs/press/2026/tbdrppreann

Summary: The fiscal year 2026 (FY26) Breast Cancer Research Program (BCRP) Transformative Breast Cancer Consortium Award supports collaborations and ideas that will transform the lives of individuals with, and/or at risk for, breast cancer and will significantly accelerate progress toward ending breast cancer. Applications must propose a synergistic, highly integrated, multidisciplinary and multi-institutional consortium of leading scientists, clinicians and breast cancer consumer advocates that will address a major problem in a way that a single investigator or group could not accomplish. The consortium’s collaborative efforts must make a transformative impact in breast cancer. All applications must address at least one of the FY26 BCRP overarching challenges or provide adequate justification for exception. If the application addresses a different fundamental issue, the application must couple it with at least one of the overarching challenges. Distinctive Features: This funding mechanism allows for up to five Principal Investigators (PIs) which includes the Consortium Director and three or four Project Team PIs. Applications must include at least one breast cancer consumer advocate per project team. Only the Consortium Director will submit a pre-application, but all PIs will need to submit at the full application stage. Be advised, failure to submit all associated (Consortium Director and Project Team PIs) applications by the full application deadline may result in administrative withdrawal.

Summary: Despite significant research investment in combat-relevant burn care, a disparity exists between newly discovered knowledge in burn care and its implementation into clinical practice across the distributed operational battlespace. The fiscal year 2026 (FY26) Military Burn Research Program (MBRP) Patient-Centered Research Award (PCRA) seeks to bridge the gap between research, practice, and policy by developing a knowledge base that provides clinically useful findings about how interventions, clinical practices, guidelines, tools, and policies can be deployed to burn patients in an austere, resource-limited, military operational environment. Distinctive Features: ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;This award mechanism must support clinical research or clinical trials but cannot support preclinical or animal research . Applications may propose prospective or retrospective research involving human subjects or human subject data. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; New for FY26: The FY26 PCRA offers a Mentorship Option at a higher funding level to support a synergistic relationship between an experienced researcher (Mentor) and one to two junior researchers (Mentees). The dual purpose of this award is to fund a primary research study addressing a critical gap in combat burn care while simultaneously fostering the development of the next generation of military burn research leaders.

Summary: The fiscal year 2026 (FY26) Amyotrophic Lateral Sclerosis Research Program (ALSRP) Pilot Clinical Trial Award (PCTA) supports the rapid implementation of clinical trials with the potential to have a significant impact on the treatment or management of amyotrophic lateral sclerosis (ALS). Projects may range from phase 1 to small-scale phase 2 trials. Applications must address one of the following focus areas: ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Biomarker-Driven Interventions: Disease-modifying interventions, with mechanism-specific biomarkers to predict which clinical trial participants are likely to respond, demonstrate target engagement, and effects on the intended biological pathway. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Clinical Care: Improving aspects of clinical care and symptom management for ALS. Distinctive Features: Funding from this award mechanism must support a clinical trial. The clinical trial should begin no later than 12 months after the award date or 18 months for U.S. Food and Drug Administration (FDA)-regulated studies. Projects proposing a therapeutic intervention (drug, biologic, and/or device) must incorporate biomarkers specific to the intervention into the trial design. All pre-applications and applications are required to incorporate community collaboration, as described in Section 3.2.2, to optimize research impact. Applications must include a detailed Regulatory Strategy plan that outlines the approach for obtaining regulatory approvals, if required, specifically for the funded portion of the study. In addition, applications must provide a separate Transition Plan that describes how the outcomes of the study will be advanced to the next phase of development, beyond the scope of the funded work.

Summary: The fiscal year 2026 (FY26) Military Burn Research Program (MBRP) Discovery Award supports innovative, untested, groundbreaking research that provides new insights and explores early concepts in combat-relevant burn care that provide the foundation for future translational and/or clinical research. The proposed project may be exploratory, hypothesis-driven, or hypothesis-generating research, but must be novel and must be based on a strong scientific rationale and a well-developed study design. Distinctive Features: The focus of this award mechanism is innovation. Proposed research should lay the groundwork for future avenues of scientific investigation or product development in the area of combat-relevant burn care. The outcome of research supported by this award should be the generation of robust preliminary data that can be used as a foundation for groundbreaking future research projects.

Summary: The Ovarian Cancer Research Program (OCRP) Investigator-Initiated Research Award is intended to support high-impact research that addresses a critical need and has the potential to make an important contribution to ovarian cancer or patient/survivor care. Distinctive Features: Application must contain strong research plan with sound scientific rational and logical reasoning. Preliminary data are required. Research projects may focus on any phase of research, from basic laboratory research through translational research, excluding clinical trials. Partnering Principal Investigator (PI) Option: The Partnering PI Option is structured so that two investigators, each of whom will be designated as a PI, will work synergistically on a single project. The results of this partnering project should significantly advance the research beyond what would be possible through individual efforts.

Summary: Created in FY23, the Ovarian Cancer Clinical Trial Academy (OCCTA) supports the next generation of Early-Career Investigators (ECIs) in clinical trial research to produce effective treatments and cures for ovarian cancer. The OCCTA, through its Leadership, provides for professional and leadership development of the ECIs to include skills and competencies needed to execute clinical trials, providing intensive mentoring, national networking, collaborations, and a peer group for junior clinical trialists. The OCCTA will bring together established investigators (the Academy Dean and Assistant Dean), established Career Guides (mentors), and a group of ECIs/Scholars to conduct successful, highly productive clinical trials in ovarian cancer. Distinctive Features: Research funded under this FY26 funding opportunity will support translational research and small-scale, early-phase clinical trials in ovarian cancer. Preliminary data are required, however, these data do not necessarily need to be derived from the ovarian cancer research field. The ECI must be within 12 years of their last postdoctoral research position (Ph.D.), clinical fellowship (M.D.), or equivalent at the time of full application submission deadline. The ECI must commit no less than 25% effort to this award and/or OCCTA activities for the first two years. The Designated Mentor must be a clinical trialist with a strong record of mentoring and training early-career investigators.

Summary: The fiscal year 2026 (FY26) Kidney Cancer Research Program (KCRP) Idea Development Award (IDA) supports the development of high-impact ideas that advance the understanding of kidney cancer and ultimately lead to improved patient outcomes. The research project should include a well-formulated, testable hypothesis based on strong scientific rationale and a well-developed and articulated research approach. Personnel on the proposed team should have a strong background in kidney cancer research. Distinctive Features: ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Partnering Principal Investigator Option: Supports meaningful and productive partnerships between two investigators, termed the Initiating Principal Investigator (PI) and Partnering PI, collaborating on a single application. Only the Initiating PI will submit a pre-application, but all PIs will need to submit full applications. The Partnering PI’s application is an abbreviated package specific to their distinct portion of the research project. Be advised, all associated applications for a research project may be withdrawn if the initiating or partnering application is rejected or administratively withdrawn.

Summary: The intent of the fiscal year 2026 (FY26) Tick-Borne Disease Research Program (TBDRP) Therapeutic/Diagnostic Research Award (TDRA) is to support product-driven therapeutic and diagnostic development research aimed at reducing the burden of Lyme disease and/or other tick-borne diseases and conditions, and improving patient care and/or quality of life. Treatment-focused applications should be therapeutic evaluation studies designed to advance new ideas aimed at drug or treatment discovery that are still in the early/preclinical stages of development. Diagnosis-focused applications should propose diagnostic approaches that will be readily integrated into clinical settings. &nbsp; https://cdmrp.health.mil/pubs/press/2026/tbdrppreann

Summary: The fiscal year 2026 (FY26) Alzheimer’s Research Program (AZRP) Transforming Care Award (TrCA) supports clinical research or clinical trials evaluating interventions, innovations, and solutions in critical areas for dementia care for individuals with Alzheimer’s disease and Alzheimer’s disease related dementia (AD/ADRD) and their care partner(s). Distinctive Features: Clinical research and clinical trials are allowed; however, clinical trials solely testing or evaluating pharmacological interventions do not meet the intent of this funding opportunity. Studies utilizing animal models do not meet the intent of the mechanism and are not allowed. Preliminary data are required. Community collaboration is required for research prospectively enrolling human subjects. The AZRP encourages studies to leverage existing cohorts/datasets. Cohorts consisting of individuals 65 years or younger are also encouraged. Career Initiation or Transition (CIT) Partnership Option: The TrCA includes an option for more than one PI and supports both new and existing collaborative partnerships. If recommended for funding, each PI will be named on separate awards to the recipient organization(s). If utilizing this option, at least one independent investigator must meet the CIT Partnership Option eligibility requirements at the time of application submission.

Summary: The fiscal year 2026 (FY26) Breast Cancer Research Program (BCRP) Breakthrough Award mechanism supports promising research with high potential to lead to or make breakthroughs in breast cancer. All applications must address at least one of the FY26 BCRP overarching challenges or provide adequate justification for exception. Applications must address the challenge in a way that can lead to a breakthrough and have major impact. The FY26 Breakthrough Award mechanism contains four different funding levels designed to support major (but not all) stages of research that will lead to clinical application. Each level specifies a distinct research scope. This program announcement discusses the Breakthrough Award Level 4. Distinctive Features: ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Clinical trials are required. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The research team must include two or more breast cancer consumer advocates. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; This funding mechanism allows for a single Principal Investigator (PI), or two partnering PIs referred to as the Initiating PI and the Partnering PI. For the Partnering PI Option (PPIO), only the Initiating PI will submit a pre-application, but both PIs will need to submit at the full application stage. Be advised, failure to submit all associated (Initiating and Partnering PI) applications by the deadline may result in administrative withdrawal.

Plasma science is a transdisciplinary field of research where fundamental studies in many disciplines, including plasma physics, plasma chemistry, materials science, and space science, come together to advance knowledge for discovery and technological innovation.&nbsp; The primary goal of the EC osystem for&nbsp; L eading&nbsp; I nnovation in&nbsp; P lasma&nbsp; S cience and&nbsp; E ngineering (ECLIPSE) program is to identify and capitalize on opportunities for bringing fundamental plasma science investigations to bear on problems of societal and technological need within the scope of science and engineering supported by the participating NSF programs. The ECLIPSE meta-program has been created to foster an inclusive community of scientists and engineers, an ecosystem spanning multiple NSF Directorates, in the pursuit of translational research at the interface of fundamental plasma science and technological innovation.&nbsp; The ECLIPSE program builds on the long history of NSF leadership in supporting multi-disciplinary research in plasma science and engineering, and is intended to enhance organizational unity within NSF, and potentially with other funding agencies, in considering proposals and supporting projects that may otherwise struggle to find a natural home within the existing hierarchy of Directorates, Divisions, and programs within the Foundation. Examples of topical areas within the scope of the ECLIPSE program include but are not limited to: Plasma surface interactions, with applications to , e.g., advanced manufacturing, materials processing, and catalysis. Atmospheric pressure plasmas and microplasmas with applications to , e.g., microelectronics, plasma agriculture, environmental remediation, and other clean and decarbonized energy goals enabled by electrification of the chemical industry. Dusty plasmas with applications to , e.g., development of nanomaterials, aerosols, and functionalized surface coatings. Novel sensor development for highly non-equilibrium plasmas with applications to , e.g., cubesat-based geospace measurements and industrial plasma diagnostics. Novel computational modeling for multi-component and/or multi-phase plasma systems with applications to , e.g., space weather prediction and plasma reactor design. Novel studies of plasmons in nano-photonics and nano-optics with applications to , e.g., sub-THz wireless communication and photocatalytic chemical processes. New chemical measurement science for characterizing processes occurring in plasmas and using plasmas as part of measurement systems with applications to , e.g., analysis of environmental contaminants or identification of forensic evidence. Study of fundamental chemical reactions and mechanisms in plasmas with applications to , e.g., novel chemical synthesis. Proposals submitted for consideration by this program should address societal or technological needs within the scope of science and engineering supported by the National Science Foundation.&nbsp; Proposals addressing technology development primarily supported by other US government funding agencies are not eligible for consideration and may be returned without review.&nbsp; Proposers are strongly encouraged to contact the cognizant Program Officers if they are unsure of the suitability of a project to this program. Proposals submitted for consideration by the ECLIPSE program should satisfy the following criteria: (1) clearly articulate the fundamental scientific and/or engineering challenge in plasma science and engineering that may be relevant to more than one NSF program; and (2) provide a substantive discussion of how a resolution of the stated scientific and/or engineering challenge will address specific societal and/or technological needs identified as priorities by the research communities, policymakers and/or other stakeholders. Depending on the nature of the proposal, the latter may be described as the Intellectual Merit or the Broader Impact of the proposed activity.&nbsp;&nbsp; The program encourages inclusion of specific efforts to increase the diversity of the ECLIPSE community and to broaden participation of under-represented groups in Science, Technology, Engineering, and Mathematics (STEM) as Broader Impacts of proposed work.&nbsp; The program welcomes proposals from Historically Black Colleges and Universities (HBCUs), other Minority Serving Institutions (MSIs), and institutions in EPSCoR-eligible jurisdictions , along with collaborations between these institutions.&nbsp; Proposers are also encouraged to address how the proposed efforts may enhance workforce development towards STEM careers associated with the field of plasma science and engineering. The ECLIPSE program is not intended to replace existing programs.&nbsp; A proposal that is requesting consideration within the context of ECLIPSE should begin the title with the identifying acronym "ECLIPSE:" and should be submitted to one of the "Related Programs" listed below. In choosing the most relevant program, proposers are advised to read program descriptions and solicitations carefully and to consult with cognizant Program Officers in advance of proposal preparation. Proposal submissions outside of the scientific scope of the receiving program may be transferred to a different program or may be returned without review. Proposers should ask for consideration and review as an ECLIPSE proposal only if the proposal addresses both of the criteria listed above.&nbsp; Proposals marked for consideration by the ECLIPSE program that do not address both of these criteria may be returned without review or reviewed within the context of an individual program. Supplement requests to existing awards within a program that address both of the above criteria may also be considered. Information Sharing with other Funding Agencies When permitted under an MOU between NSF and another funding agency, NSF may share information from proposals for consideration of joint funding and may invite employees of such organizations to attend merit review panels as observers.

Summary: The fiscal year 2026 (FY26) Military Burn Research Program (MBRP) Technology/Therapeutic Development Award (TTDA) is a burn-focused, product-driven award mechanism intended to provide support for the translation of promising preclinical findings into burn products for clinical application in an austere, resource-limited, distributed operational environment. Distinctive Features: The technology or therapeutic product(s) to be developed must be product-oriented (e.g., medical device, drug, or clinical practice guidelines involving a therapeutic or technology). The product(s) to be developed may be tangible or knowledge supporting the development of a tangible product and must address one or more of the FY26 MBRP TTDA focus areas. Knowledge products are allowable, provided that the knowledge is applicable to a technology or therapeutic under development. (A “knowledge product” is a non-tangible, non-materiel product that results from research with the potential to improve individual or public health.) ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; New for FY26: The FY26 MBRP TTDA offers a Mentorship Option at a higher funding level to support a synergistic relationship between an experienced researcher (Mentor) and one to two junior researchers (Mentees). The dual purpose of this award is to fund a primary research study addressing a critical gap in combat burn care while simultaneously fostering the development of the next generation of military burn research leaders.

Summary: The Ovarian Cancer Pilot Award supports research that expands or modifies current thinking about and/or approaches in ovarian cancer, exploring innovative concepts or theories in ovarian cancer that could ultimately lead to critical discoveries or major advancements that will drive the field forward. Distinctive Features: Innovation is key. Research projects that demonstrate exceptional scientific merit but lack innovation do not meet the intent of the mechanism. Preliminary data are not required but are allowed for this mechanism. This mechanism includes a blinded pre-application component. Pre-applications to this funding opportunity will undergo a blinded pre-application screening. While preparing your pre-application, do not include any material that may identify the PI, a collaborator, or the organization of the PI or collaborator.

Summary: The fiscal year 2026 (FY26) Autism Research Program (ARP) Career Development Award supports early-career, independent investigators and/or the transition of established investigators from other research fields to conduct innovative, high-impact ideas or early-phase, proof-of-principle clinical trials with the potential to have a major impact on autism. Distinctive Features: Applications are strongly encouraged to address one of the FY26 ARP Career Development Award Areas of Interest or provide justification that the proposed research addresses a critical problem, question, or need in autism. FY26 Career Development Award submissions with a pilot clinical trial component are required to include community collaborations to optimize research impact. Applications are expected to name at least one community partner (e.g., an Autistic individual or caregiver, representatives of community-based organizations) who will provide advice and consultation throughout the planning and implementation of the research project.

Summary: Initially created in FY09, the OCRP Ovarian Cancer Academy (OCA) is a unique, interactive virtual academy providing intensive mentoring, national networking, collaborations, and a peer group for junior faculty. The overarching goal of the OCA is to conduct innovative and impactful ovarian cancer research while developing successful, highly productive ovarian cancer researchers in a collaborative research and career development environment. Distinctive Features: The OCA is a virtual career development and research training platform that consists of Early-Career Investigators (ECIs), their Designated Mentors, and an Academy Dean and Assistant Dean. The OCA-ECI Award is not a traditional career development award; the ECI is expected to participate in monthly webinars and annual workshops and to communicate and collaborate with other members of the Academy (other ECIs, Mentors, the Dean and Assistant Dean) as well as with the advocacy community.

The Analysis Program supports research in analysis. Areas of current activity include complex, harmonic, and real analysis; dynamical systems and ergodic theory; functional analysis; mathematical physics; operator theory and operator algebras; partial differential equations and calculus of variations. Conferences Proposals to the Analysis Program for conferences or workshops must be submitted through the program solicitation "Conferences and Workshops in the Mathematical Sciences" (link below). Principal Investigators should carefully read the solicitation to obtain important information regarding the substance of proposals for conferences, workshops, and similar activities. To facilitate timely notification of the availability of support, proposals for conferences, workshops, and similar activities should be submitted 8 months in advance of the start date of the proposed event.

Summary: The fiscal year 2026 (FY26) Breast Cancer Research Program (BCRP) Breakthrough Award mechanism supports promising research with high potential to lead to or make breakthroughs in breast cancer. All applications must address at least one of the FY26 BCRP overarching challenges or provide adequate justification for exception. Applications must address the challenge in a way that can lead to a breakthrough and have major impact. The FY26 Breakthrough Award mechanism contains four different funding levels designed to support major (but not all) stages of research that will lead to clinical application. Each level specifies a distinct research scope. This program announcement discusses the Breakthrough Award Level 3. Distinctive Features: ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; For this funding mechanism, small-scale clinical trials are allowed but not required. Applications proposing projects with a clinical trial should be submitted under the Clinical Trial option. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The research team must include two or more breast cancer consumer advocates. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; This funding mechanism allows for a single Principal Investigator (PI), or two partnering PIs referred to as the Initiating PI and the Partnering PI. For the Partnering PI Option (PPIO), only the Initiating PI will submit a pre-application, but both PIs will need to submit at the full application stage. Be advised, failure to submit all associated (Initiating and Partnering PI) applications by the deadline may result in administrative withdrawal.

Summary: The fiscal year 2026 (FY26) Amyotrophic Lateral Sclerosis Research Program (ALSRP) Clinical Outcomes and Biomarkers Award (COBA) supports the development and/or validation of clinical outcomes and biomarkers to enrich clinical trials in amyotrophic lateral sclerosis (ALS). Projects can be relevant to a specific therapy, a class of therapeutics, or to a specific ALS subtype (such as a particular genetic mutation) and do not have to broadly apply to all patients. Distinctive Features: To meet the intent of the funding opportunity, applications may address clinical biomarkers and/or clinical outcomes . This may include the identification, development, and/or validation of promising biomarkers for ALS, which may include, but are not limited to susceptibility/risk, diagnostic, monitoring/disease progression, prognostic, predictive, response, or safety biomarkers. Clinical Outcomes projects may focus on the identification, development, and/or validation of clinician-, observer-, or patient-reported, and/or performance outcome measures for ALS. Projects may include the optimization of current outcome measures already in use. Applications may utilize digital health measures, including wearable devices, smart-phone sensors, video or voice recordings, imaging studies, or other devices which record disease-relevant physiological data and/or outcomes. Community Collaboration is an important element of the FY26 ALSRP COBA. Applicants will be expected to articulate how the proposed research question or study design was informed by the ALS lived experience community.

Summary: The fiscal year 2026 (FY26) Arthritis Research Program (ATRP) Clinical Research Award (CRA) supports clinical research that evaluates disease-specific factors and interventions. Research is intended to generate clinically useful evidence with potential to optimize patient outcomes and inform clinical care or policy. Research addressing any and all types of arthritis is encouraged. Applications must address one of two FY26 ATRP CRA Focus Areas: Prevention and Early Diagnosis, or Treatment and Mitigation of Disease Progression/Burden. Distinctive Features: The FY26 ATRP CRA offers funding for two research levels. It is the responsibility of the applicant to select the level that aligns with the scope of the proposed research. • Research Level 1: Applications proposing clinical research or early-phase/pilot clinical trials, to include new or emerging research that is not ready for a full-scale randomized controlled clinical trial. • Research Level 2: Applications proposing a full-scale clinical trial. Applications should include a community collaborator (e.g., patient/care partner, community-based organization consultant) who will provide advice and consultation during study design and throughout study planning and implementation. The ATRP encourages a community collaborator for Research Level 1 applications and requires a community collaborator for Research Level 2 applications. Preliminary and/or published data are required.

Summary: The fiscal year 2026 (FY26) Autism Research Program (ARP) Idea Development Award supports the development of innovative, high-risk/high-reward research that could lead to critical discoveries or major advancements that will accelerate progress in improving outcomes for Autistic individuals. This award mechanism is designed to support innovative ideas with the potential to yield impactful data and new avenues of investigation. Distinctive Features: Applications are strongly encouraged to address one of the FY26 ARP Idea Development Award Areas of Interest or provide justification that the proposed research addresses a critical problem, question, or need in autism. Partnering Principal Investigator (PI) Option: The Partnering PI Option is structured so that two investigators, each of whom will be designated as a PI, will work synergistically on a single project. The results of this partnering project should significantly advance the research beyond what would be possible through individual efforts.

Summary: The fiscal year 2026 (FY26) Amyotrophic Lateral Sclerosis Research Program (ALSRP) Therapeutic Development Award (TDA) supports research ranging from preclinical validation of therapeutic leads through U.S. Food and Drug Administration (FDA) Investigational New Drug (IND)-enabling studies. The proposed studies are expected to be empirical in nature and product-driven. Applicants with limited amyotrophic lateral sclerosis (ALS) experience are strongly encouraged to include collaborators with substantial experience in the relevant ALS model systems, endpoints and pathophysiology. Applications supported by this award must begin with lead compounds in hand and must already demonstrate proof-of-concept efficacy data in at least one appropriate preclinical model system of ALS, including whole-animal and cellular model systems. Distinctive Features: Mechanism-specific , predictive/cohort-selective, target engagement and pharmacodynamic biomarker development, in parallel to the main therapeutic effort, is a critical component of the FY26 ALSRP Therapeutic Development Award . If appropriate mechanism-specific biomarkers are already available or currently in development, how the existing biomarkers will improve trial design, patient selection, and efficiency or interpretation of the proposed ALS therapeutic approach must be apparent in the application. Development of biomarkers for the purposes of diagnosis, prognosis, or measurement of general disease progression without consideration of the therapeutic development process will not be supported. Therapeutic candidates which have already been granted an IND are not appropriate for this mechanism.

Summary: The fiscal year 2026 (FY26) Alzheimer’s Research Program (AZRP) Transforming Diagnosis Award (TrDA) supports non-incremental, solutions-oriented research that reduces or overcomes important barriers to obtaining a diagnosis, meaningful disease monitoring and accurate prognosis. Distinctive Features: Clinical research is allowed, however clinical trials and animal research are prohibited. Preliminary data are required. Community collaboration is required for studies prospectively enrolling human subjects. Study Population: The AZRP encourages studies to leverage existing cohorts/datasets. Cohorts consisting of individuals 65 years or younger are also encouraged. Career Initiation or Transition (CIT) Partnership Option: The TrDA includes an option for more than one PI and supports both new and existing collaborative partnerships. If recommended for funding, each PI will be named on separate awards to the recipient organization(s). If utilizing this option, at least one independent investigator must meet the CIT Partnership Option eligibility requirements at the time of application submission.

The Universe is the ultimate laboratory, and we can now probe it as never before through several powerful and diverse windows &ndash; electromagnetic waves, high-energy particles, and gravitational waves. Each of these windows provides a different view. Together they reveal a detailed picture of the Universe that will allow us to study matter, energy, and the cosmos in fundamentally new ways. The &ldquo;Windows on the Universe&rdquo; Multi-Messenger Astrophysics (WoU-MMA) program identifies three categories of messengers - electromagnetic waves, high-energy particles including neutrinos and cosmic rays, and gravitational waves. The goals of WoU-MMA are to build the capabilities and accelerate the synergy between observations and theory to realize integrated, multi-messenger astrophysical explorations of the Universe. The WoU-MMA program welcomes proposals in any area of research supported through the participating divisions that address at least one of the following criteria: Coordination: Activities to coordinate observations involving more than one messenger. Observations: Observations of astrophysical objects or phenomena that are potentially sources of more than one messenger. Interpretation: Theory, experiment, simulations and other activities to understand or interpret observations of astrophysical objects that are sources of more than onemessenger. Competitive proposals will accelerate the progress in multi-messenger astrophysics and advance the community activities that have been developed during the initial five-year period of the WoU-MMA program. These build on observational and analysis capabilities at the intersection of the explorations enabled by each of the three windows. Efforts to integrate research communities to develop full interoperability between the three windows, and to develop a skilled new workforce in this field, are also encouraged. Proposals should be submitted to the relevant programs listed below (see Related Programs). The WoU-MMA program is not intended to replace existing programs that make awards that involve experimental or theoretical efforts related to each of the three messengers. Rather, the WoU-MMA program is meant to fund awards that have significant components of multi-messenger astrophysics. Priority will be given to proposals for dedicated efforts that significantly advance the WoU-MMA goals. A proposal that is requesting consideration within the context of WoU-MMA should begin the title with the identifying acronym "WoU-MMA:". PIs should ask for consideration and review as a WoU-MMA proposal only if the proposal addresses at least one of the criteria listed above. Proposals marked for consideration by the WoU-MMA program that do not address at least one of these criteria will be reviewed solely within the participating program(s) to which they were submitted. Supplement requests to existing awards within a program that address one of the above criteria will also be considered.

Summary: The fiscal year 2026 (FY26) Peer Reviewed Medical Research Program (PRMRP) Platform Clinical Translation Award supports the translational development and/or early-phase clinical trials for broadly applicable clinical technologies that will address urgent and complex needs related to two congressionally directed FY26 PRMRP topic areas. The platform product in development should address one of the FY26 PRMRP portfolio-specific strategic goals and address the health care needs of military Service Members, Veterans and their Families. Distinctive Features: Allows for multiple Principal Investigators (PIs). The proposed experiments may represent a single project led by a single PI, or it may consist of partnerships between principal investigators that will occur synergistically to advance a platform product. One PI will be identified as the Initiating PI and will be responsible for the majority of the administrative tasks associated with application submission. Up to two additional PIs can be identified as Partnering PIs. If recommended for funding, each PI will be named on separate awards to the recipient organization(s). Requires a PI-convened external advisory board with patient advocate participation. The patient advocate must be a person living with, or a family member or caretaker of someone with, a disease or condition addressed in one of the applicant-selected congressionally directed FY26 PRMRP topic areas. Funding Details: The Congressionally Directed Medical Research Programs (CDMRP) expects to allot roughly $30M to fund approximately two Platform Clinical Translation Award applications with total cost caps of $15M per award. The maximum period of performance is 4 years. It is anticipated that awards made from this FY26 funding opportunity will be funded with a maximum of $8M in FY26, with the remaining budget to be funded out of future fiscal years depending upon meeting performance-based milestones and availability of future funds, which will expire for use on September 30, 2032. Awards supported with FY26 funds will be made no later than September 30, 2027.

The Combinatorics program supports research on discrete structures and includes algebraic, enumerative, existential, extremal, geometric, and probabilistic combinatorics, including graph theory. Conferences Principal Investigators should carefully read the program solicitation &quot;Conferences and Workshops in the Mathematical Sciences&quot; (link below) to obtain important information regarding the substance of proposals for conferences, workshops, summer/winter schools, and similar activities. Conference proposals must be submitted at least six months in advance of the conference, and in the same fiscal year (which begins October 1) if possible.

The program in Foundations supports research in mathematical logic and the foundations of mathematics, including proof theory, recursion theory, model theory, set theory, and infinitary combinatorics. Conferences Principal Investigators should carefully read the program solicitation &quot;Conferences and Workshops in the Mathematical Sciences&quot; (link below) to obtain important information regarding the substance of proposals for conferences, workshops, summer/winter schools, and similar activities. Conference and workshop proposals should be submitted eight months before the requested start date.

The program in Geometric Analysis supports research on differential geometry and its relation to partial differential equations and variational principles; geometric methods in modern mathematical physics; symplectic geometry; geometric group theory; geometric data analysis; aspects of global analysis, including convex, complex, integral, and information geometries; and related geometric topics. Conferences Geometric Analysis proposals for conferences, workshops, summer/winter schools, and similar activities must be submitted to PD 22-1265 using the "Conference" or &ldquo;Travel&rdquo; proposal type in research.gov. The program&rsquo;s submission windows for conference/travel proposals are September 1-30 and April 1-30. Proposals with budgets not exceeding $50,000 should be submitted during a submission window that occursat least six months prior to the event. Proposals with budget requests that exceed $50,000 should be submitted during a submission window that occursat least eight months prior to the event. Principal Investigators should carefully read the relevant sections of the PAPPG to obtain important information regarding the substance of such proposals and note the additional requirements for travel support requests for international events.

The Topology program supports research on algebraic topology, including chromatic, equivariant, motivic, and (un)stable homotopy, homology and cohomology theories; bordism and K-theory; topological manifolds; knots and links; geometric topology; differential topology; transformation groups; topological quantum field theories; contact and symplectic structures; infinity and model categories; and topological data analysis. Conferences Topology proposals for conferences, workshops, summer/winter schools, and similar activities must be submitted to PD 22-1267 using the "Conference" or &ldquo;Travel&rdquo; proposal type in research.gov. The program&rsquo;ssubmission windows for conference/travel proposalsare September 1-30 and April 1-30. Proposals with budgets not exceeding $50,000 should be submitted during a submission window that occursat least six months prior to the event. Proposals with budget requests that exceed $50,000 should be submitted during a submission window that occursat least eight months prior to the event. Principal Investigators should carefully read the relevant sections of the PAPPG to obtain important information regarding the substance of such proposals and note the additional requirements for travel support requests for international events.

Summary: The fiscal year 2026 (FY26) Duchenne Muscular Dystrophy Research Program (DMDRP) Idea Development Award (IDA) promotes new ideas that are still in the early stages of development and have the potential to yield impactful data and new avenues of investigation. This award supports impactful, high-risk/high-reward research that could lead to critical discoveries or major advancements that will accelerate progress in improving outcomes for individuals with Duchenne muscular dystrophy (DMD) in the near term. Applications should include a well-formulated, testable hypothesis based on strong scientific rationale. The DMDRP strongly encourages research projects investigating therapies designed to demonstrate efficacy cross the life span, including infants, toddlers and nonambulatory individuals. Distinctive Features: The FY26 DMDRP IDA mechanism offers three eligibility career categories: • The Established Investigator category is for independent investigators at all academic levels, or equivalent • The New Investigator – Early-Stage category is for independent investigators early in their careers (i.e., within 10 years of their first faculty appointment or equivalent). Applicants in this category will be reviewed separately from Established Investigators. • The New Investigator – Transitioning category is for independent investigators at all academic levels, or equivalent, in an area other than muscular dystrophy who are seeking to transition to a career in DMD, thereby bringing their expertise to the field. Applicants in this category will be reviewed separately from Established Investigators. Preliminary data relevant to DMD that supports the feasibility of the research hypotheses and research approaches are required for all applications. Clinical trials or clinical trial aims are not allowed.

Summary: The fiscal year 2026 (FY26) Neurofibromatosis Research Program (NFRP) Synergistic Idea Award (SIA) supports new ideas that represent synergistic approaches to neurofibromatosis (NF) research involving two or three Principal Investigators (PIs). These investigators should utilize their complementary and synergistic perspectives to address a central problem or question in NF research. Applications must include preliminary and/or published data that are relevant to NF and the proposed research project. Distinctive Features: • Partnering Principal Investigators: One PI will be identified as the Initiating PI and will be responsible for the majority of the administrative tasks associated with application submission. An additional one or two PI(s) will be identified as a Partnering PI. Each partner will be recognized as a PI, submit a separate application (even if the partners are at the same organization), and receive an individual award.

Summary: The fiscal year 2026 (FY26) Neurofibromatosis Research Program (NFRP) Exploration-Hypothesis Development Award (EHDA) supports the initial exploration of innovative, high-risk, high-gain, and potentially groundbreaking concepts in neurofibromatosis (NF) research. Studies supported by this award mechanism should lay the groundwork for future avenues of scientific investigation. The proposed research project should include a well-formulated, testable hypothesis based on strong scientific rationale and study design. Distinctive Features: • Innovation: The proposed research project should be innovative. Innovative research may introduce a novel paradigm, challenge existing paradigms, examine existing problems from novel perspectives, or exhibit other highly creative qualities. • Preliminary Data: Preliminary and/or published data is encouraged but not required.

Summary: Supports studies that further develop mature ideas, expand upon key discoveries, and have the potential to make significant advances in bone marrow (BMF) failure research and/or patient care. Investigator-Initiated Research Award (IIRA) applications may involve translational and clinical research including studies in preclinical models, research with human data and/or anatomical substances, and research with human subjects, as well as correlative studies associated with a clinical trial(s); however, this award mechanism does not support clinical trials. IIRA applications may also support Investigational New Drug (IND)-enabling efforts such as lead compound characterization, and assessments of formulation and stability, absorption, distribution, metabolism and excretion, dose/response and toxicology. Distinctive Features: This funding mechanism allows for a partnering Principal Investigator (PI). Only the initiating PI will submit a pre-application, but both PIs will need to submit full applications. The partnering PI application is an abbreviated package specific to their distinct portion of the research project. Be advised, all associated applications for a research project may be withdrawn if the initiating or partnering application is rejected or administratively withdrawn. This award mechanism requires preliminary data relevant to the proposed project. Applications can support clinical research studies; however, this mechanism does not allow clinical trials.

Summary: The fiscal year 2026 (FY26) Neurofibromatosis Research Program (NFRP) Neurofibromatosis Research Academy – Scholar Award (NFRA-SA) supports early-career independent investigators (Scholars) joining the Neurofibromatosis Research Academy to pursue a neurofibromatosis project that may include basic, translational, and/or clinical research. The proposed research should address at least one of the FY26 NFRP Areas of Emphasis, under the leadership of the NFRA Director and Deputy Director. The overarching goal of the NFRA is to conduct innovative and impactful research in the field of neurofibromatosis disorders while developing successful, highly productive NF researchers in a collaborative research and career development environment. Distinctive Features: • Scholar: The Scholar, named as the Principal Investigator, must be less than 10 years of completion of their terminal degree by the time of the application deadline (excluding time spent in residency, clinical training, or on family medical leave). • Career Guide: This award mechanism requires each Scholar to designate a Career Guide for guidance. The Career Guide is not required to be at the same institution as the Scholar; however, if the (primary) Career Guide is from a different institution, the application must identify a secondary Career Guide at the Scholar’s institution.

Summary: The fiscal year 2026 (FY26) Neurofibromatosis Research Program (NFRP) Investigator-Initiated Research Award (IIRA) supports high-impact research that addresses a critical need and has the potential to make important contributions to the field of neurofibromatosis disorders or advance patient care. Research projects may focus on any phase of research, excluding clinical trials. The rationale for a research idea may be derived from laboratory discovery, population-based studies, a clinician’s firsthand knowledge of patients, or anecdotal data. Applications must include preliminary and/or published data that are relevant to NF and the proposed research project. Distinctive Features: This award mechanism offers two funding levels based on participation in two optional features: • Open Science Initiative: Catalyzes research for neurofibromatosis through early access to data and data sharing within the neurofibromatosis community. • Optional Qualified Collaborator: Encourages collaborative research between basic scientists and clinical researchers, and between academic and biotechnology scientists. The funding levels are defined as follows: • Level 1: Applications without an optional feature. • Level 2: Applications including one of the optional features.

Summary: The fiscal year 2026 (FY26) Peer Reviewed Medical Research Program (PRMRP) Clinical Trial Award supports the rapid implementation of clinical trials with the potential to have significant impact on the treatment and management of a disease or condition addressed in one of the congressionally directed FY26 PRMRP topic areas and FY26 PRMRP strategic goals. Distinctive Features: Must support a clinical trial. Supports two different application categories, based on the phase of planning for the clinical trial: Clinical Trial Only or Clinical Trial with Planning Phase. The Clinical Trial with Planning Phase option is intended to support the final phase of regulatory activities and planning activities that are necessary to be completed prior to initiation of the clinical trial. The planning phase cannot be used to finalize the intervention or support animal studies. Applications that already have regulatory approvals in place and are submitting to the Clinical Trial Only option may be prioritized over those requesting the Planning Phase option. Animal studies are not supported. Studies must complete all preclinical empirical laboratory work prior to the award start date. Supports three funding levels, each offered with and without a Planning Phase: Funding Level 1: Supports phase 0 or phase 1 clinical trials or non-phased trials with fewer than 100 participants. Funding Level 2: Supports phase 2 clinical trials or non-phased trials with fewer than 300 participants. Funding Level 3: Supports phase 3 clinical trials or non-phased trials with more than 300 participants. Funding Details: The Congressionally Directed Medical Research Programs (CDMRP) expects to allot roughly $94.5M to fund approximately 9 Clinical Trial Award applications with total cost caps of $800,000 for the planning phase of a Clinical Trial with Planning Phase, $6M for Funding Level 1, $10M for Funding Level 2, and $20M for Funding Level 3 per award. The maximum period of performance is 4 years for the clinical trial, and 12 months for the planning phase. It is anticipated that awards made from this FY26 funding opportunity will be funded with FY26 funds, which will expire for use on September 30, 2032. Awards supported with FY26 funds will be made no later than September 30, 2027.

Summary: The fiscal year 2026 (FY26) Bone Marrow Failure Research Program (BMFRP) Resource Development Award (RDA) supports the development of a multiomic atlas generated from well-annotated human bone marrow failure (BMF) samples, with omic data derived from marrow specimens. The resulting dataset should serve as an open-access, durable resource for the BMF research and clinical communities and is expected to facilitate key discoveries that advance the understanding of BMF diseases. Distinctive Features: The application must include a robust Data Resource Sharing Plan that describes the means and timeline by which the fully developed resource will be made available to the scientific and clinical community.

Summary: The fiscal year 2026 (FY26) Parkinson’s Research Program (PRP) Investigator-Initiated Research Award (IIRA) supports highly rigorous, multidisciplinary, high-impact research projects that have the potential to make an important contribution to Parkinson’s disease research. Research must address at least one of the four FY26 PRP Focus Areas . Distinctive Features: ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Partnering Principal Investigator (PI) Option: Allows for more than one PI. One PI will be identified as the Initiating PI and will be responsible for the majority of the administrative tasks associated with application submission. The other PI(s) will be identified as Partnering PI(s), with a maximum of two Partnering PIs. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Preliminary data are required. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Clinical trials are allowed.

Summary: The fiscal year 2026 (FY26) Parkinson’s Research Program (PRP) Early Investigator Research Award (EIRA) supports Parkinson’s disease (PD) research for investigators in the early stages of their careers. The FY26 EIRA offers two funding levels, which align to the research career stage of the Principal Investigator (PI). Funding Level 1 (for fellows) requires the investigator to receive guidance from a designated Mentor, whereas Funding Level 2 (for early-career independent investigators) does not. Proposed research must address at least one of the four FY26 PRP Focus Areas . Distinctive Features: ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The Early Investigator is considered the PI of the application and must exhibit strong potential for and commitment to pursuing a career as an investigator at the forefront of PD research; however, the PI is not required to have previous PD research experience. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Funding Level 1: Applications must include at least one Mentor appropriate to the proposed research project who has experience in PD research and mentoring, as demonstrated by a record of active funding, recent publications, and successful mentorship. The selected Mentor(s) should also demonstrate a clear commitment to the development of the PI toward independence as a PD researcher. Preliminary data are encouraged but not required . ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Funding Level 2: Mentor not required. Preliminary data are required . ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Clinical trials are not allowed.

Summary: The fiscal year 2026 (FY26) Reconstructive Transplant Research Program (RTRP) Concept Award supports the exploration of highly innovative new concepts or untested theories that address an important problem relevant to reconstructive transplantation. The Concept Award does not support clinical trials . Distinctive Features: ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Innovation: Innovative research may introduce a new paradigm, challenge existing paradigms, examine existing problems from new perspectives, or exhibit other highly creative qualities. Research that is an incremental advance upon published data is not considered innovative. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Relevance: Projects should address at least one of the FY26 RTRP Focus Areas. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Preliminary Data: Presentation of preliminary data is not allowed; however, applications should demonstrate the ability to achieve interpretable results. A rationale for the proposed work must be provided. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Early-Career Investigators: Early-career investigators are encouraged to apply. Investigators at or above the level of postdoctoral fellow are eligible to apply.

Summary: The fiscal year 2026 (FY26) Reconstructive Transplant Research Program (RTRP) Investigator-Initiated Research Award supports studies that have the potential to make an important contribution to reconstructive transplant research, patient care, and/or quality of life. All projects must demonstrate solid scientific rationale with military-relevant utility. The Investigator-Initiated Research Award does not support clinical trials . Distinctive Features: ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Scope: Applications may focus on any phase of research from basic through translational, including preclinical studies in animal models, and clinical research in human subjects or human anatomical substances. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Study Design and Feasibility: The study design should be rigorous and support maximal reproducibility and translational feasibility. A strong statistical plan with appropriate power analysis is important. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Impact: Project results should have the potential for long- and short-term impact on the reconstructive transplant research field and/or patient community. Projects should address at least one of the FY26 RTRP Focus Areas. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Preliminary Data: Preliminary and/or published data that are relevant to reconstructive transplantation and support the rationale for the proposed research must be included. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Military Relevance: All projects must be responsive to the health care needs of military Service Members and/or Veterans recovering from traumatic injury, and/or their Family members, caregivers, or clinicians, as well as the general public. Collaboration with military researchers and clinicians is encouraged but not required.

Summary: The fiscal year 2026 (FY26) Duchenne Muscular Dystrophy Research Program (DMDRP) Clinical/Translational Research Award (CTRA) supports advanced translational research to accelerate promising ideas in Duchenne muscular dystrophy (DMD) research toward clinical applications. Research must address at least one of the FY26 CTRA Focus Areas. Research projects investigating therapies that will be efficacious across the life span are strongly encouraged. Distinctive Features: The FY26 CTRA offers two funding levels: • Funding Level 1 to support smaller, less complex preclinical and/or clinical research. • Funding Level 2 to support larger, more complex preclinical and/or clinical research. The FY26 CTRA also offers a Partnering PI Option (PPIO) to support meaningful and productive partnerships between two investigators collaborating on the proposed research project. The PPIO has two eligibility categories: • Early-Career Partnering PI category for an independent, early-career investigator within 10 years of their first faculty appointment (or equivalent) by the time of application submission. • Established Interdisciplinary Partnering PI for independent investigators at all academic levels, or equivalent, in an area other than muscular dystrophy, seeking to transition to a career in DMD, thereby bringing their expertise to the field. Preliminary data are required for all applications. Pilot clinical trials and clinical trial readiness studies to better inform development of drugs, devices, and other interventions are allowed.

The Probability Program supports research on the theory and applications of probability. Subfields include discrete probability, stochastic processes, limit theory, interacting particle systems, stochastic differential and partial differential equations, and Markov processes. Research in probability which involves applications to other areas of science and engineering is especially encouraged. Conferences Principal Investigators should carefully read the program solicitation &quot;Conferences and Workshops in the Mathematical Sciences&quot; (link below) to obtain important information regarding the substance of proposals for conferences, workshops, summer/winter schools, and similar activities. Conference and workshop proposals should be submitted eight months before the requested start date.

Summary: The fiscal year 2026 (FY26) Vision Research Program (VRP) Investigator-Initiated Research Award (IIRA) supports basic through early translational research that will yield highly impactful discoveries or major advancements in the research and/or patient care of eye injury and/or visual dysfunction related to military exposure . The IIRA may be used to support preclinical studies and/or clinical research . Research must align with at least one of the FY26 VRP Focus Areas . The IIRA cannot be used to support clinical trials . Distinctive Features: ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The IIRA offers two Funding Levels to support research at different stages and the exploration/development of ideas of different maturity levels. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Funding Level 2 includes a Partnering Principal Investigator (PI) Option (PPIO) for two PIs, an Initiating PI and a Partnering PI. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Scored peer review criteria include Research Idea/Rationale, Research Strategy and Feasibility, Impact, and Personnel. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Programmatic review criteria include adherence to the intent of the IIRA, contribution to the VRP portfolio, relative impact, and relevance to military health. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The VRP may share FY26 IIRA applications and reviews with the National Eye Institute (NEI) for independent funding consideration. https://cdmrp.health.mil/pubs/press/2026/vrppreann

Proposals in the area of plasma physics submitted to the Division of Physics that are not governed by another solicitation (such as CAREER), should be submitted to the Division-wide solicitation: Division of Physics: Investigator-Initiated Research Projects . The Plasma Physics program participates in multiple NSF meta-programs such as the ECosytem for Leading Innovation in Plasma Science and Engineering (ECLIPSE) , Windows on the Universe: The Era of Multi-Messenger Astrophysics (WoU-MMA) , and Computational and Data-enabled Science and Engineering (CDS&amp;E) . Topically appropriate proposals may also be submitted to the Plasma Physics program in response to NSF Dear Colleague Letters such as Critical Aspects of Sustainability (CAS): Innovative Solutions to Sustainable Chemistry (CAS-SC) . When permitted under an MOU between NSF and another funding agency or private foundation, NSF may share information from proposals submitted to this solicitation for consideration of joint funding, and may invite employees of such organizations to attend merit review panels as observers. MOUs of relevance to the Plasma Physics program presently exist with the Department of Energy/Office of Science, National Nuclear Security Administration, the Air Force Office of Scientific Research, the US-Israel Binational Science Foundation, the Czech Science Foundation, Deutsche Forschungsgemeinschaft (DFG, German Research Foundation), and the Swiss National Science Foundation. Plasma Physics is a study of matter and physical systems whose intrinsic properties are governed by collective interactions of large ensembles of free charged particles. 99.9% of the visible Universe is thought to consist of plasmas. The underlying physics of the collective behavior in plasmas has applications to space physics and astrophysics, materials science, applied mathematics, fusion science, accelerator science, and many branches of engineering. The Plasma Physics program supports research that can be categorized by several broad, sometimes overlapping, sub-areas of the discipline, including: magnetized plasmas in the laboratory, space, and astrophysical environments; high energy density plasmas; low temperature plasmas; dusty, ultra-cold, and otherwise strongly coupled plasmas; non-neutral plasmas; and intense field-matter interaction in plasmas. The focus of the Plasma Physics program is to generate an understanding of the fundamental principles governing the physical behavior of a plasma via collective interactions of large ensembles of free charged particles, as well as to improve the basic understanding of the plasma state as needed for other areas of science and engineering. Principal Investigators (PIs) are encouraged to consider including specific efforts to increase diversity of the plasma physics community and broaden participation of under-represented groups in Science, Technology, Engineering, and Mathematics (STEM) as Broader Impacts of proposed work. Development of new undergraduate and graduate plasma physics curricula, or curricula enhancement to include plasma physics topics in other courses, at institutions lacking such coursework is similarly encouraged. NSF recognizes that some research projects within this Program may require more than three years to realize demonstrable research outcomes. For such projects, PIs are encouraged to consult the above Program Director to discuss the possibility of submitting a proposal of 4- or 5-year duration. Some Plasma Physics-related activities are supported primarily by other NSF Programs. Proposals focused on the physical properties of individual or a small number of atoms or molecules, or optical physics, should be directed to the Atomic, Molecular, and Optical Physics Program within the Division of Physics. Proposals focused on understanding astrophysical systems should be directed to the Division of Astronomical Sciences. Proposals focused on understanding the Geospace environment or the Sun-Earth interactions should be directed to an appropriate program within the Geospace Section of the Division of Atmospheric and Geospace Sciences. Proposals focused on development of new materials using plasmas should be directed to an appropriate program in the Division of Materials Research. Proposals focused on plasma-assisted manufacturing should be directed to the Division of Civil, Mechanical and Manufacturing Innovation. Finally, proposals focused on use of plasmas for environmental and reaction engineering, environmental sustainability, combustion systems, or engineering of biomedical systems should be directed to an appropriate program within the Division of Chemical, Bioengineering, Environmental and Transport systems.

Summary: The fiscal year 2026 (FY26) Spinal Cord Injury Research Program (SCIRP) Clinical Trial Award (CTA) supports the rapid implementation of clinical trials with the potential to have a significant impact on the treatment or management of spinal cord injury (SCI). Distinctive Features: This funding opportunity contains an Early-Career Partnership Option, which allows for two Principal Investigators (PIs). If this option is selected, at least one of the named PIs must be an early-career investigator. Only the Initiating PI will submit a pre-application, but all PIs will need to submit full applications. The Partnering PI’s application is an abbreviated package specific to their distinct portion of the research project. If recommended for funding, each PI will be named on a separate award to the recipient organization(s). Be advised, all associated applications for a research project may be withdrawn if the initiating or partnering application is rejected or administratively withdrawn. Applications to this funding opportunity must name at least two spinal cord injury (SCI) community partners (e.g., SCI Lived-Experience Consultants, representatives of community-based organizations) who will provide advice and consultation throughout the planning and implementation of the research project.

The Applied Mathematics program supports mathematics research motivated by and contributing to the solution of problems arising in science and engineering. Successful proposals must demonstrate mathematical innovation, as well as breadth and quality of impact on applications. Projects that additionally provide opportunities for rigorous mathematical training of junior applied mathematicians through their involvement in research are encouraged. The proposals considered by the Applied Mathematics program may range from single investigator to interdisciplinary team projects. Conferences Proposals to the Applied Mathematics program for conferences or workshops should be submitted through the program solicitation "Conferences and Workshops in the Mathematical Sciences" (link below). Principal Investigators should carefully read the program solicitation to obtain important information regarding the substance of proposals for conferences, workshops, summer/winter schools, and similar activities. To facilitate timely notification of the availability of support: Proposals for conferences, workshops, etc., to be held in the US must be submitted 8 months in advance of the conference date; Proposals to support group travel to meetings outside the US must be submitted 12 months in advance of the meeting date; Proposals for conferences, workshops, etc., whose budget request exceeds $50,000 must be submitted during the annual November submission window.

Summary: The fiscal year 2026 (FY26) Spinal Cord Injury Research Program (SCIRP) Clinical Translation Research Award (CTRA) supports high-impact, new, or emerging clinical research that requires additional preliminary studies, such as feasibility, pilot, or optimization, to prepare for future larger-scale clinical trials or implementation. Primary objectives of this mechanism include: • Accelerating the translation of current and emerging techniques or interventions into clinical use by addressing specific barrier(s) to clinical success for the purpose of de-risking or informing the design of definitive trials. • Identifying the most effective diagnosis, treatment and rehabilitation options to support critical decision-making for patients, clinicians, care partners and policymakers. Distinctive Features: • This funding opportunity contains an Early-Career Partnership Option, which allows for two principal investigators (PIs). If this option is selected, at least one of the named PIs must be an early-career investigator. Be advised, all associated applications for a research project may be withdrawn if the initiating or partnering application is rejected or administratively withdrawn. • Applications to this funding opportunity must name at least two spinal cord injury (SCI) community partners who will provide advice and consultation throughout the planning and implementation of the research project.

Summary: The fiscal year 2026 (FY26) Hearing Restoration Research Program (HRRP) Focused Research Award (FRA) supports promising research that accelerates drug discovery and therapeutic development for hearing restoration after military-relevant auditory system injury. The FRA may be used to support preclinical studies and/or clinical research. Research must align with at least one of the FY26 HRRP Focus Areas. The FRA cannot be used to support clinical trials, tinnitus research or vestibular research. Distinctive Features: • The FRA offers two Funding Levels to support research at different stages and the exploration/development of ideas of different maturity levels. • Funding Level 2 includes a Partnering Principal Investigator (PI) Option (PPIO) for two PIs, an Initiating PI and a Partnering PI. • Scored peer review criteria include Research Idea/Rationale, Research Strategy and Feasibility, Impact, and Personnel. • Programmatic review criteria include adherence to the intent of the FRA, contribution to the HRRP portfolio, relative impact, and relevance to military health.

The Advanced Technologies and Instrumentation for the Astronomical Sciences (ATI) program provides individual investigator and collaborative research grants for the development of new technologies and instrumentation for use in ground-based astronomy and astrophysics.The program supports achieving the science objectives of the Division of Astronomical Sciences. The development of innovative, potentially transformative, technologies and instruments are sought, even at high technical risk.Supported categories include (but are not limited to):advanced technology development, concept feasibility studies, and specialized instrumentation to enable new observations that are difficult or impossible to obtain with existing means.Proposals may include hardware and/or software development and/or analysis to enable new types of astronomical observations. Access to the ATI supported technology and instrumentation development efforts by the US astronomical community is viewed as an important metric of success. An annual Principal Investigators meeting is planned to disseminate information between the funded research efforts.

Summary: The fiscal year 2026 (FY26) Vision Research Program (VRP) Mentored Clinical Research Award (MCRA) supports patient-oriented vision injury research conducted by highly motivated military or civilian clinicians in training. The MCRA may be used to support a standalone study of high impact to vision injury care or the generation of clinical research data in preparation for a more expansive study. Research must align with at least one of the FY26 VRP Focus Areas . The MCRA may not be used to support preclinical research or clinical trials . Distinctive Features: ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Key personnel must include an established clinician or Ph.D. clinical scientist, who will serve as Principal Investigator (PI) and a clinician in training (e.g., a fellow, resident, junior clinician, clinician in a Ph.D. program), who will conduct the proposed research under mentorship of the PI, with support from supporting personnel as appropriate. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The clinician in training should have sufficient time remaining in their training program to complete the research proposed under the MCRA.&nbsp; ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Scored peer review criteria include Research Idea/Rationale, Research Strategy and Feasibility, Impact and Personnel. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Programmatic review criteria include adherence to the intent of the MCRA, contribution to program portfolio, relative impact and relevance to military health. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Applicants must submit documentation of Institutional Review Board (IRB)/Ethics Committee (EC) approval or exemption by January 1, 2027 , in order for the MCRA application to be considered for funding.&nbsp; https://cdmrp.health.mil/pubs/press/2026/vrppreann

The Astronomy and Astrophysics Research Grants (AAG) Program is an inclusive and flexible funding opportunity to support research in the astronomical sciences. The Program provides individual investigator and collaborative research grants for observational, theoretical, laboratory, and archival data studies in astronomy and astrophysics. The Program also considers proposals for projects and tools that enable or enhance astronomical research. Proposals may span multiple disciplines and/or areas of study and may utilize multiple techniques.

Summary: The fiscal year 2026 (FY26) Spinal Cord Injury Research Program (SCIRP) Translational Research Award (TRA) supports translational research that will accelerate the movement of promising ideas in spinal cord injury (SCI) research into clinical applications. Distinctive Features: • This funding opportunity contains an Early-Career Partnership Option, which allows for two principal investigators (PIs). If this option is selected, at least one of the named PIs must be an early-career investigator. Only the initiating PI will submit a pre-application, but all PIs will need to submit full applications. The partnering PI’s application is an abbreviated package specific to their distinct portion of the research project. If recommended for funding, each PI will be named on a separate award to the recipient organization(s). Be advised, all associated applications for a research project may be withdrawn if the initiating or partnering application is rejected or administratively withdrawn. • Applications to this funding opportunity must name at least one SCI community partner (e.g., SCI Lived-Experience Consultant, representative of community-based organizations) who will provide advice and consultation throughout the planning and implementation of the research project.

Summary: The fiscal year 2026 (FY26) Neurofibromatosis Research Program (NFRP) Neurofibromatosis Research Academy – Leadership Award (NFRALA) supports visionary, established neurofibromatosis (NF) investigators with documented history of neurofibromatosis funding, publications, strong mentorship and commitment to leadership to serve as Director and Deputy Director of the Neurofibromatosis Research Academy. The Academy Director and Deputy Director will execute a multi-institutional, interactive, virtual research academy that consists of scholars, who are early-career investigators, and their career guides, who serve as the scholars’ primary mentors. Distinctive Features: • Academy Director: Established NF investigators at or above the level of Associate Professor, or equivalent, at the full application submission deadline. • Academy Deputy Director: Investigators at or above the level of Associate Professor, or equivalent, at the full application deadline and affiliated with a different institution than the Academy Director. • Pilot Research Project: The Academy Director and Deputy Director will conduct one or more pilot research projects in collaboration with the academy scholars. Preliminary and/or published data relevant to NF and the proposed research project are encouraged but not required.

Summary: The fiscal year 2026 (FY26) Vision Research Program (VRP) Translational Research Award (TRA) supports translational research that transforms a promising discovery into new drugs, devices or clinical practice guidelines that are ready for definitive testing in clinical trials during or by the end of the period of performance. The TRA may be used to support preclinical studies, clinical research or a pilot clinical trial , but not a full-scale clinical trial . Research must align with at least one of the FY26 VRP Focus Areas . Distinctive Features: ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;If developing new drugs or device(s), the research team must include expertise in the regulatory approval process. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The TRA includes a Partnering Principal Investigator (PI) Option (PPIO) for two PIs, an Initiating PI and a Partnering PI. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Scored peer review criteria include Research Idea/Rationale, Research Strategy and Feasibility, Impact, Personnel and Post-Award Transition Plan. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Programmatic review criteria include adherence to the intent of the TRA, contribution to the VRP portfolio, relative impact and relevance to military health. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The VRP may share FY26 TRA applications and reviews with the National Eye Institute (NEI) for independent funding consideration. https://cdmrp.health.mil/pubs/press/2026/vrppreann

Summary: The fiscal year 2026 (FY26) Vision Research Program (VRP) Clinical Trial Award (CTA) supports the rapid implementation of clinical trials with the potential to have a significant impact on the treatment or management of service-connected eye injury and visual dysfunction. Research must align with at least one of the FY26 VRP Focus Areas . &nbsp; Distinctive Features: ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;For interventions that require Investigational New Drug (IND)/Investigational Device Exemption (IDE) or equivalent regulatory authorizations for clinical testing, the IND/IDE application or equivalent must be submitted to the relevant Regulatory Agency by the CTA application submission deadline. In addition, applicants must provide documentation of communication from the Regulatory Agency indicating that the IND/IDE or equivalent is active/safe to proceed by March&nbsp;1, 2027, in order for the CTA application to be considered for funding. Refer to Attachment&nbsp;7: Regulatory Strategy for further details. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Scored peer review criteria include Clinical Impact; Research Strategy and Feasibility; Recruitment, Accrual, Retention; Regulatory Strategy and Transition Plan; Statistical Plan and Data Analysis; Ethical Considerations; Personnel and Communication. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Programmatic review criteria include adherence to the intent of the CTA, contribution to program portfolio, relative impact and relevance to military health. https://cdmrp.health.mil/pubs/press/2026/vrppreann

Summary: The fiscal year 2026 (FY26) Joint Warfighter Medical Research Program (JWMRP) Military Medical Research and Development Award (MMRDA) mechanism is intended to fund the logical continuation of previous Department of War (DOW)-funded research and development efforts relevant to the FY26 JWMRP that augment and accelerate high-priority medical requirements to meet the needs of Service Members and other Military Health System beneficiaries. The MMRDA supports a wide range of research projects spanning late-stage preclinical studies, late-state technology development efforts, technology demonstration, translational, and clinical research. Projects must be relevant to at least one of the FY26 JWMRP focus areas. Distinctive Features: To be eligible for JWMRP funding, applicants/offerors must have already received DOD/DOW core or DOD/DOW Congressional Special Interest funding. An MMRDA Clinical Research or Clinical Trial Option (MMRDA-CRCTO) is available to specifically support clinical research/observational studies, all phases of clinical trials/interventional studies, and/or correlative studies in support of the development of promising pharmaceutical or biologic candidates, medical devices and technologies. Applicants/offerors should select MMRDA-CRCTO when the application/proposal involves research that includes any human subjects, human biological samples (prospective or retrospective) or human data sets. Note: If selecting this option, applicants must submit additional relevant application/proposal materials.

The U.S. National Science Foundation Directorate for Mathematical and Physical Sciences (NSF MPS) supports multiple research programs in the astronomical sciences. NSF MPS funds foundational astronomical sciences research and instrumentation focused on exploring space and advancing fundamental understanding of the universe. The programs covered by this funding opportunity are: Astronomical Sciences Core Research Astronomical Sciences Technology &amp; Instrumentation Astronomical Sciences Innovations Research supported by these programs is essential for ongoing discovery in a range of fields. The programs provide a strong scientific foundation for America's capabilities in multiple areas: predicting solar storms, discovering potentially habitable planets in other solar systems, understanding the physical workings of extreme astrophysical objects like black holes, and more. NSF MPS is particularly interested in intellectually ambitious and potentially transformative foundational research. Proposals need not promise a near-term product, deployment, or commercial outcome, nor need they address later-stage development to be competitive. &nbsp;

Summary: The fiscal year 2026 (FY26) Spinal Cord Injury Research Program (SCIRP) Investigator-Initiated Research Award (IIRA) supports studies that have the potential to make an important contribution to spinal cord injury (SCI) research, patient care and/or quality of life. May focus on any phase of research from basic through translational science, though studies that focus solely on identifying intervention targets are discouraged. Distinctive Features: • This funding opportunity contains an Early-Career Partnership Option, which allows for two Principal Investigators (PIs). If this option is selected, at least one of the named PIs must be an early-career investigator. Only the initiating PI will submit a pre-application, but all PIs will need to submit full applications. The partnering PI’s application is an abbreviated package specific to their distinct portion of the research project. If recommended for funding, each PI will be named on a separate award to the recipient organization(s). Be advised, all associated applications for a research project may be withdrawn if the initiating or partnering application is rejected or administratively withdrawn.

Summary: The fiscal year 2026 (FY26) Combat Readiness – Medical Research Program (CRRP) Translational Research Award (TRA) supports hypothesis-driven innovative, high-impact translational research that will accelerate the movement of promising ideas and/or technologies in trauma care into solutions to maximize casualty survivability, improve patient care closer to the point of injury and/or trauma care guidelines. Preliminary data are required. Research using well-validated animal models is allowed. Distinctive Features: • **NEW for FY26** An investigator may be named as the Principal Investigator (PI) on only one FY26 CRRP TRA application. • Research supported by the FY26 CRRP TRA must represent a mature, translational research effort with a minimum biomedical technology readiness level (TRL) of 4 or knowledge readiness level (KRL) of 4.

Summary: The fiscal year 2026 (FY26) Lung Cancer Research Program (LCRP) Translational Research Award (TRA) supports advanced translational research that will foster transformation of promising ideas in lung cancer into clinical applications. Research must address at least one of the FY26 LCRP areas of emphasis. Distinctive Features: This funding mechanism intends to support a broad range of translational studies and allows application submission under: Funding Level 1 – Advanced/late-stage preclinical work or correlative studies; or Funding Level 2 – Pilot clinical trials of novel interventions.

Summary: The fiscal year 2026 (FY26) Rare Cancers Research Program (RCRP) Resource and Community Development Award (RCDA) supports the development of research resources and clinical or preclinical datasets that will advance the field of rare cancers research and ultimately improve outcomes for individuals with rare cancers. Research supporting this funding opportunity should fill one of the following major gaps: Lack of research and clinical resources, including patient tissues, cell and tumor models. Lack of communication and dissemination strategies within scientific and patient communities for sharing rare cancers research and clinical findings. Lack of infrastructure for sharing data and other resources. Lack of therapeutics and mechanistic research to inform treatment development. Distinctive Features: Documentation of plans for engagement and partnerships with Patient Advocates throughout the life cycle of the research study from development of the research question through execution of the study. Community building and enhancement are key components. A description of the dissemination and sustainability of the platform for scientific and/or clinical and patient community is required. Preliminary data are not required but may be included to address feasibility.

Summary: The fiscal year 2026 (FY26) Lung Cancer Research Program (LCRP) Patient-Centered Outcomes and Survivorship Award (PCOSA) promotes evidence-based and patient-centered approaches to improve health and lung cancer related outcomes and enhance the patient experience in defined populations. Research must address at least one of the FY26 LCRP areas of emphasis in the Health Outcomes and Survivorship category. Distinctive Features: • This funding mechanism requires the research team to include an advocate who is a lung cancer patient/survivor or caregiver. • This funding mechanism allows proposed projects to include translational or clinical research, including pilot clinical trials.

Summary: The fiscal year 2026 (FY26) Prostate Cancer Research Program (PCRP) Data Science Award (DSA) supports research that develops or uses quantitative and analytical approaches, processes and/or systems to obtain knowledge and insight from large and/or complex sets of prostate cancer data in one or more of the following research areas: Analysis of clinically annotated datasets; analysis of -omics data; artificial intelligence and machine learning; bioinformatics; computational biology; digital pathology; epidemiology; and medical imaging. All applications must address one of the FY26 PCRP Overarching Challenges . Distinctive Features: This funding mechanism allows for multiple Principal Investigators (PIs). Only the initiating PI will submit a pre-application, but all PIs will need to submit full applications. The partnering PI application is an abbreviated package specific to their distinct portion of the research project. Be advised, all associated applications for a research project may be withdrawn if the initiating or partnering application is rejected or administratively withdrawn.

Summary: The fiscal year 2026 (FY26) Rare Cancers Research Program (RCRP) Idea Development Award (IDA) promotes ideas that are ready for further development and have the potential to yield high-impact findings and new avenues of investigation. Distinctive Features: The RCRP encourages applicants to include an exploratory aim or sub-aim to support any necessary discovery-driven research. Preliminary data with disease-specific rationale are required. However, these data do not necessarily need to originate from studies of the proposed rare cancer type(s)/subtype(s) under study. Research should have high potential impact on rare cancers and the patient community.

Summary: The fiscal year 2026 (FY26) Lung Cancer Research Program (LCRP) Idea Development Award (IDA) supports conceptually innovative, high-risk/high-reward research that could lead to critical discoveries or major advancements that will accelerate progress toward eradicating deaths and suffering from lung cancer. This mechanism promotes new ideas that are in the early stages of development and have the potential to yield impactful data and new avenues of investigation. Research must address at least one of the FY26 LCRP areas of emphasis. Distinctive Features: This FY26 LCRP IDA mechanism has a New Investigator category that is designed to allow applicants early in their faculty appointments to compete for funding separately from established investigators. Preliminary data to support the feasibility of the research hypotheses and research approaches are required; however, these data do not necessarily need to be derived from studies of lung cancer.

Summary: The fiscal year 2026 (FY26) Toxic Exposures Research Program (TERP) Clinical Trial Award (CTA) mechanism supports the advancement, execution, and analysis of clinical trials with the potential to have a significant impact on the prevention, treatment, or management of symptoms, diseases or conditions associated with or resulting from military-related toxic exposures. Proposed projects may range from small proof-of-concept clinical trials (e.g., pilot, first-in-human, phase 0) designed to demonstrate the feasibility or inform the design of more advanced trials, through large-scale trials (including pragmatic clinical trials) to determine efficacy in relevant patient populations. &nbsp; Distinctive Features: To encourage applications that include meaningful and productive collaborations, the FY26 TERP CTA includes a Partnering Principal Investigator Option (PPIO) . One Principal Investigator (PI) is identified as the initiating PI, and an additional PI may be identified as a Partnering PI. If recommended for funding, each PI will be named on separate awards. The intent is to support interdisciplinary partnerships, such as those between clinicians and research scientists, that will accelerate the movement of promising interventions/​knowledge products into clinical applications. Partnering should significantly advance the research beyond what would be possible through independent efforts. https://cdmrp.health.mil/pubs/press/2026/terppreann

Summary: The fiscal year 2026 (FY26) Prostate Cancer Research Program (PCRP) Physician Research Award (PRA) Supports a mentored research experience to prepare physicians with clinical duties for careers in prostate cancer research. All applications must address one of the FY26 PCRP Overarching Challenges . Distinctive Features: ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Early-Career Clinician Investigator: Serves as the Principal Investigator (PI). Includes investigators with clinical duties in the last year of an accredited medical residency or medical fellowship program, or within five years of initiating a faculty appointment. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Mentorship: Applications must include at least one mentor who demonstrates experience in prostate cancer research and successful mentorship. ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Researcher Development Plan: Applications must include a research development plan articulating an individualized strategy for acquiring necessary skills, competence and expertise to complete the projects and foster the PI’s career development. https://cdmrp.health.mil/pubs/press/2026/pcrppreann